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  6. Ultra High-Speed High-Resolution LC [ACQUITY UPLC PLUS]

Ultra High-Speed High-Resolution LC [ACQUITY UPLC PLUS]

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last updated:Jan 22, 2026

日本ウォーターズ(米国本社 Waters Corporation) 
日本ウォーターズ(米国本社 Waters Corporation) 
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Demonstrates excellent analytical skills. LC improves lab productivity, efficiency, and throughput simultaneously.

UltraPerformance LC (UPLC) is the result of a total system innovation that has redesigned all aspects of traditional HPLC, including packing material technology, column design, injectors, fluid delivery systems, and detectors. UPLC technology was developed to simultaneously enhance laboratory productivity, efficiency, and throughput for scientists seeking reliable technology. Its success has already been demonstrated through thousands of peer-reviewed papers, application notes, and significant process improvements, making UPLC a standard technology that delivers important scientific and business benefits in leading companies and research institutions around the world. We offer a diverse lineup that allows for effective use of this technology not only in research settings but also in production management. Since the launch of ACQUITY UPLC in 2004, Waters has continued to pursue further innovations, and the new ACQUITY UPLC PLUS series has been introduced, achieving even greater flexibility, performance, and ease of use.

    Separation deviceAnalytical Equipment and Devices
H-PLUS.jpg

Ultra High-Speed High-Resolution LC [ACQUITY UPLC PLUS]

H-PLUS.jpg
H-PLUS.jpg
  • Waters ACQUITY UPLC homepage
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[ACQUITY UPLC I-Class PLUS System] - Achieves high-efficiency and rapid separation with industry-leading ultra-low dispersion and low delay volume. - Demonstrates excellent analytical capability even for very complex and low-concentration samples, making it suitable as an MS inlet. [ACQUITY UPLC H-Class PLUS System] - A hybrid LC that can be used as both HPLC and UPLC. - A system that balances the performance of UPLC with the operability of HPLC. - Transforms existing standard analytical conditions into top-class performance. [UPLC 2D System] - A 2D chromatography system in UPLC mode. - Achieves separations that cannot be accomplished in standard HPLC/UPLC modes.

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Ultra-High-Performance Liquid Chromatography [ACQUITY I-Class System]

Ultra-High-Performance Liquid Chromatography [ACQUITY I-Class System]

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Ultra-high-speed high-resolution liquid chromatography [ACQUITY H-Class System]

Ultra-high-speed high-resolution liquid chromatography [ACQUITY H-Class System]

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Cosmetics & Personal Care Analysis Solution Catalog

Cosmetics & Personal Care Analysis Solution Catalog

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High-Sensitivity Quantification of Nitrosamines Application Note

High-Sensitivity Quantification of Nitrosamines Application Note

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News about this product(3)

LC Basic Course Available from Tomorrow, Total of 5 Sessions, Held in May-June [Live Webinar]

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Waters offers a wide range of products related to liquid chromatography, including analytical columns, mass spectrometers, sample preparation products, and informatics. We will be holding a basic LC course for those who are just starting to use LC. This content is ideal for new employees, those using LC for the first time, and anyone who wants to review the basics of LC. Additionally, since it will be in a live webinar format, there will be real-time Q&A sessions during each session, so please feel free to participate and ask questions. Date: Please refer to the table below Time: 15:00 - 16:00 Location: Online Capacity: 1000 participants per session Participation fee: Free May 12, 2026 (Tuesday) Session 1: Basics of Chromatography May 19, 2026 (Tuesday) Session 2: Basics of LC Columns May 26, 2026 (Tuesday) Session 3: Basics of Sample Preparation June 2, 2026 (Tuesday) Session 4: Basics of LC-MS June 16, 2026 (Tuesday) Session 5: LC Basics Q&A Collection

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[On-Demand Webinar] Pharmaceutical Analysis User Presentation 1: Kaigen Pharmaceutical Co., Ltd. "Development of Testing Methods Using the Analytical Method and Method Development Software Fusion"

  • Seminar・Event

In this seminar, we will introduce case studies of analytical method development using QbD software: Fusion, and present solutions that are helpful for developing robust analytical methods. ◆ Development of testing methods using the analytical method and method development software Fusion Dr. Taiki Kamiya, Kaken Pharmaceutical Co., Ltd. The analysis department of the CMC Center, to which the speaker belongs, has been developing testing methods using HPLC and introduced Fusion four years ago to improve operational efficiency. This time, we will explain the introduction environment, background, and overview of Fusion, and introduce the operational methods used in the department. Additionally, we will share impressions of using Fusion (advantages and challenges) as well as examples of testing method development (successes and failures). ◆ Waters Analytical Development Solutions, Waters Japan We will introduce mass spectrometers that can be used in conjunction with QbD software, LC systems that enable smooth development and transfer of analytical methods, and the quality of analytical columns, which is crucial for conducting robust analyses over the long term.

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[On-Demand Webinar] Chemical Analysis Course: From HALS/Lubricant Quantitative Analysis to Structural Analysis of Synthetic Resins

  • Seminar・Event

In recent years, with the advancement and enhancement of polymer materials, various additives for synthetic polymers with different functions have been used in optimized formulations. Among them, there are types of additives, such as hindered amine light stabilizers (HALS) and lubricants, that present challenges in solubility and detection methods, making analysis difficult. Additionally, when conducting structural analysis of multi-component polymers or terminal group analysis using pyrolysis gas chromatography-mass spectrometry (PyGC/MS), there are many pyrolysis products not registered in the EI method database, making analysis not straightforward. In this webinar, we will introduce two solutions to the challenges in the characterization of synthetic resins, along with practical examples. ■ Overview of additives for synthetic polymers ■ Actual quantitative analysis of HALS/lubricants ■ Examples of structural analysis of synthetic resins using PyGC/Q-Tof MS Target audience: Individuals handling organic compounds for the development and quality control of materials and industrial products.

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日本ウォーターズ(米国本社

日本ウォーターズ(米国本社 Waters Corporation) 

Testing, Analysis and Measurement

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Waters Corporation, headquartered in Milford, Massachusetts, USA, has played a pioneering role as a specialized manufacturer of liquid chromatography since its establishment in 1958. Actively engaged in the development of new products and technologies, it has grown into an international group company that supplies not only high-performance liquid chromatography but also mass spectrometers (MS) and thermal analysis instruments. Waters Japan started operations in 1973 (Showa 48) as the Japanese base of Waters Corporation. Inheriting the corporate ethos of the U.S. headquarters, we have made "Customer Success" our mission and continue to provide innovative technologies and lab solutions.

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