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  6. [Analysis Case] Observation of Fine Surface Morphology of Three-Dimensional Cultured Human Skin

[Analysis Case] Observation of Fine Surface Morphology of Three-Dimensional Cultured Human Skin

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last updated:Mar 13, 2025

一般財団法人材料科学技術振興財団 MST
一般財団法人材料科学技術振興財団 MST
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Visualization of nanoscale roughness on the skin surface using AFM.

In recent years, the development of alternative methods to animal testing for the efficacy and safety testing of pharmaceuticals and cosmetics has been progressing, with particular attention being paid to testing methods using three-dimensional cultured skin. In this case study, a percutaneous absorption test of a cosmetic (lotion) was conducted using three-dimensional cultured human skin, which was measured using AFM (Atomic Force Microscopy). This allows for a visual evaluation of the microstructure of the skin surface, and it is also possible to quantitatively assess the roughness of any specific area. By measuring under atmospheric conditions, it is possible to observe the samples while minimizing alterations that would occur under vacuum conditions.

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C0496.jpg

[Analysis Case] Observation of Fine Surface Morphology of Three-Dimensional Cultured Human Skin

C0496.jpg
C0496.jpg AFM像.png 測定方法.png プロファイルデータ.png データ表.png
  • Related Link - https://www.mst.or.jp/casestudy/tabid/1318/pdid/43…
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Analysis of biotechnology, pharmaceuticals, and cosmetics.

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[Analysis Case] Observation of Micro-Shape on the Surface of Three-Dimensional Cultured Human Skin_C0496

[Analysis Case] Observation of Micro-Shape on the Surface of Three-Dimensional Cultured Human Skin_C0496

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Technical information "Transdermal absorption evaluation using three-dimensional cultured human skin with TOF-SIMS and LC/MS/MS" and two other items have been released.

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We have published the following two analysis case studies on the MST website: - Evaluation of transdermal absorption using three-dimensional cultured human skin with TOF-SIMS and LC/MS/MS - Observation of the fine surface morphology of three-dimensional cultured human skin For more details, please visit the MST website. http://www.mst.or.jp/

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一般財団法人材料科学技術振興財団 MST

一般財団法人材料科学技術振興財団 MST

Testing, Analysis and Measurement

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MST is a foundation that provides contract analysis services. We possess various analytical instruments such as TEM, SIMS, and XRD to meet your analysis needs. Our knowledgeable sales representatives will propose appropriate analysis plans. We are also available for consultations at your company, of course. We have obtained ISO 9001 and ISO 27001 certifications. Please feel free to consult us for product development, identifying causes of defects, and patent investigations! MST will guide you to solutions for your "troubles"!

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