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  6. Cosmetic ingredient 2-αGG 100% CICA cosmetic ingredient Glycoin

Cosmetic ingredient 2-αGG 100% CICA cosmetic ingredient Glycoin

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last updated:Nov 07, 2025

HIGUCHI INC.
HIGUCHI INC.
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Achieved 100% purity of 2αGG, the most active isomer of the miraculous resurrection plant, through our unique manufacturing technology. High moisturizing, wound healing, and cell revitalization functions.

Glycoin natural is a product composed of 100% unique structural isomers manufactured using patented biotechnology by Bitop AG in Germany. These structural isomers are found only in the miraculous resurrection plant Myrothamnus flabellifolia and blue-green algae (spirulina), which are known as the miracle plants of the desert that can revive green with just a small amount of water even after being dried for 50 years. Glycoin natural activates the rejuvenating power of tired skin, stressed skin, and aging skin. <Efficacy> Stimulates cell regeneration, growth factors, and ATP synthesis Activates antioxidant enzymes (SOD1, SOD2, CAT) Immediate moisturizing effect improved by 49% (after one application) Skin elasticity improved by 93% Skin smoothness improved by 61% Skin thickness increased by 9.9% Reduces sunburn and skin redness Tissue repair and wound healing effects maintained for 48 hours

    Cosmetic materials and raw materialsOther pharmaceutical intermediates and cosmetic ingredientsOther medical supplies and cosmetic manufacturing materials
Glycoin

Cosmetic ingredient 2-αGG 100% CICA cosmetic ingredient Glycoin

Glycoin natural 表紙_page-0001.jpg
Glycoin natural 表紙_page-0001.jpg
  • Related Link - https://premium.ipros.jp/higuchi-inc/product/categ…
  • Special site - Product/service details - https://pr.mono.ipros.com/higuchi-inc/product/

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The German company Bitop is the first in the world to develop Ectoin. It produces Ectoin using a patented manufacturing method (fermentation method) that utilizes the extremophilic microorganism Halomonas elongata. The company's Ectoin is used not only in cosmetics but also abroad as OTC pharmaceuticals in various formulations such as creams for atopic dermatitis, eye drops, nasal sprays, and mouthwashes, with established safety and efficacy. They hold various data for cosmetics. Bitop's product strategy is "to draw ideas from nature and add science." In addition to Ectoin, they also produce a natural glycerol glucoside, which is the most cell-activating structural isomer derived from the miraculous resurrection plant, synthesized 100% enzymatically.

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Skincare products Baby care products Sun care products (after sun) Wound care products etc.

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Cosmetic ingredients for cell activation, wound healing, and CICA cosmetics: Glycoin natural.

Cosmetic ingredients for cell activation, wound healing, and CICA cosmetics: Glycoin natural.

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Cosmetic ingredients: ultimate moisturizing, protection, femcare material Ectoin(R) natural.

Cosmetic ingredients: ultimate moisturizing, protection, femcare material Ectoin(R) natural.

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Cosmetic ingredient TanActine (natural polysaccharide)

Cosmetic ingredient TanActine (natural polysaccharide)

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Cosmetic Ingredients Bitop Corporation Formulation Guide -Skin Oasis-

Cosmetic Ingredients Bitop Corporation Formulation Guide -Skin Oasis-

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Cosmetic ingredients UV, BL, IR protection plant extract Soliberin (SOLIBERINE)

Cosmetic ingredients UV, BL, IR protection plant extract Soliberin (SOLIBERINE)

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Cosmetic ingredient Miracle Revival Plant Extract (Moisturizing & Anti-Stress) Jellisin

Cosmetic ingredient Miracle Revival Plant Extract (Moisturizing & Anti-Stress) Jellisin

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Cosmetic ingredient oil-soluble ectoine Ectoine Oil (ECTOinOIL)

Cosmetic ingredient oil-soluble ectoine Ectoine Oil (ECTOinOIL)

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News about this product(2)

Suppression of "inframaging" by natural multifunctional bioactive substances.

Cosmetics Development Exhibition - Cosmetics Technology/Solution Seminar - Suppression of Inflammation by Natural Active Substances

  • Seminar・Event

The globally discussed "inflammaging" in skincare refers to the inflammatory response associated with cellular aging. In this presentation, I will explain the causes, mechanisms, and latest research findings on inflammaging, as well as how bitop's Ectoin(R) natural alleviates it and the mechanisms behind this effect. Additionally, I will present data on the calming effects and repair benefits against inflammation (retinoid) reactions caused by retinol as an application example. <Ectoin(R) natural effectiveness> Anti-aging Wrinkle depth: -32%, flaking occurrence: -76%, roughness: -86%, skin elasticity: +82.4%, brightness improvement: +3%, pigmentation removal: -28%, hair follicles: 80% improvement Anti-pollution effect MMP1 inhibition (MP): -42%, etc. Light protection - Protects against light such as UVA/UVB/BL/IRA Others Long-term moisture retention (7 weeks): +200%, erythema suppression: -38%, barrier function recovery: -28%

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Report on the 10th COSME Tech 2020 Cosmetics Development Exhibition

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From January 20 to 22, 2020, we exhibited at the 10th COSME Tech 2020, organized by Reed Exhibitions Japan Co., Ltd., held at Makuhari Messe. Thank you very much for visiting our booth during the event. Thanks to your support, we were able to conclude the event successfully. During the exhibition, in addition to bitop's Ectoin, we introduced products from Mirexus: ultra-high molecular weight 3D dendritic polymers, among others. If you have any questions regarding the exhibited items or the products listed in our catalogs, please feel free to reach out to us. We will respond to the inquiries received during the event in due course. We look forward to your continued support. <Product Introduced During the Event> bitop: Ectoin, Glycoin Mirexus: Ultra-high molecular weight 3D dendritic polymers Contipro: Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, New Hyaluronic Acid Derivatives Odycea: Plankton Glass Flower, Marine Bamboo, etc.

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HIGUCHI

HIGUCHI INC.

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Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.

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