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  6. Analysis case: Evaluation of the mechanical properties of the pericardium using a planar biaxial testing machine.

Analysis case: Evaluation of the mechanical properties of the pericardium using a planar biaxial testing machine.

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last updated:Jul 10, 2025

TA Instruments Japan  (TAInstruments)
TA Instruments Japan (TAInstruments)
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This is an introduction to medical-related analysis cases by a specialist in analysis. This time, we will present measurement cases of mechanical properties and fatigue tests that are useful for evaluating the pericardium.

The planar biaxial testing machine (TestBench testing device) is designed to conduct tests similar to those performed on a load frame. This allows for the evaluation of the sample's stiffness, strength, and durability, as well as the measurement of yield strength, ultimate strength, and fatigue life. A modular approach that includes multi-channel and multi-axis options enables a wide range of configurations and performance. It uses 200N and 400N ElectroForce linear motors mounted on a horizontal base plate to accommodate various testing needs.

    Analytical Equipment and Devices
イプロス_サムネイル(心膜).jpg

Analysis case: Evaluation of the mechanical properties of the pericardium using a planar biaxial testing machine.

イプロス_サムネイル(心膜).jpg
イプロス_サムネイル(心膜).jpg
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This time, TA Instruments introduces the "ElectroForce Series," a fatigue testing machine. In this article, we will present a case study on the evaluation of the mechanical properties of pericardium using a planar biaxial testing machine, related to cell culture and medical applications. ❖ Evaluation of the Mechanical Properties of Pericardium Using a Planar Biaxial Testing Machine The pericardial tissue was attached to the planar biaxial testing machine, and equal displacements were applied to each axis to measure the load. It was found that the load at a larger displacement was greater on the 90° axis than on the 0° axis, indicating that the mechanical properties of the measured pericardial tissue exhibit anisotropy. ■ Load Capacity: 200N, 400N ■ Motor: ElectroForce Linear Motor ■ Displacement Range: 13mm ■ Control Functions: Load, Displacement, Strain Control ■ Mounting Options: Horizontal or Vertical ■ Accessories: Physiological Saline Bath, Multi-Axis Load Options ■ Test Profiles: Single push-to-failure, pull-to-failure, repetitive loading, creep/stress relaxation measurement

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Applications: ◆ Evaluation of sample rigidity, strength, and durability ◆ Measurement of yield strength, ultimate strength, and fatigue life ◆ Assessment of material anisotropy ◆ Testing of biomaterials and tissues ◆ Testing of polymers, elastomers, and thin films Examples of achievements: ◇ Fatigue testing of metallic materials (ISO 1099) ◇ Dynamic load testing of surgical implants (ISO 14801) ◇ Elongation cycle fatigue testing of rubber properties (ASTM D4482) ◇ Testing of bone plates (ASTM F382) ◇ Testing of medical metal bone screws (ASTM F543)

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[Analysis Case] Evaluation of the Mechanical Properties of the Pericardium Using a Plane Bi-Axial Testing Machine

[Analysis Case] Evaluation of the Mechanical Properties of the Pericardium Using a Plane Bi-Axial Testing Machine

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*Application Closed* April Online LIVE Seminar Held! ~Battery Seminar~

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On April 2nd (Friday), we will start an online seminar on batteries, inviting Mr. Yoshiyasu Saito from the National Institute of Advanced Industrial Science and Technology, Energy and Environment Division, Energy Conservation Research Department. We hope you find it useful for your research and development of batteries. Additionally, there will be a presentation from our group company, Japan Waters. We look forward to your applications. 【Participation Tool】Zoom *You can also participate via a web browser. (Participation is possible without downloading the Zoom application) Participation fee: Free Please refer to the detailed page for content and application information. We will notify you of the participation details via email one week before the event. Mr. Yoshiyasu Saito, National Institute of Advanced Industrial Science and Technology 【Title】Utilization of Thermal Measurement and Thermal Analysis in Research and Development of Lithium-Ion Batteries Others

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*Application Closed* February Online LIVE Seminar Held! ~Pharmaceutical Seminar~

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★ Announcement of Online Seminar on Pharmaceuticals to be Held on February 10 ★ On February 10, we will hold a seminar on the analysis and evaluation of pharmaceuticals, featuring Dr. Kawakami from the National Institute for Materials Science (Group Leader/Chief Researcher of the Medical Application Soft Matter Group, also a Professor in the Graduate School of Pure and Applied Sciences at Tsukuba University). Additionally, there will be a presentation from our group company, Waters Japan. We look forward to your applications. 【Participation Tool】Zoom *You can also participate via a web browser. (Participation is possible without downloading the Zoom application) Participation Fee: Free Please refer to the detailed page for content and application information. We will notify you of the participation details via email one week before the event. Dr. Wataru Kawakami, National Institute for Materials Science [Title] Thermal Analysis Equipment as a Research Tool for Pharmaceuticals: Advanced Utilization Beyond Mere Evaluation Methods Others

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*Application Closed* July Online LIVE Seminar Held! ~Solid Polymer~

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★ Online Seminar on Polymer Materials: <Fracture, Fatigue, and Viscoelasticity> ★ We will hold an online seminar on polymer materials focusing on <fracture, fatigue, and viscoelasticity>. This time, we are pleased to invite Professor Emeritus Yu Ishikawa from Yamagata University, who will give a lecture on the fracture mechanisms of solid polymers and toughening. Additionally, we will present measurement case studies from our company. Please feel free to join from your home or workplace. 【Participation Tool】Zoom *You can also participate via a web browser. (Participation is possible without downloading the Zoom application) Participation Fee: Free *Due to software specifications, there is a limit on the number of participants. Please apply early. For details on the content and registration, please see the detailed page. We will also notify you of the course details via email one week before the event.

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*Application Closed* July Online LIVE Seminar Held! ~Protein Analysis~

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★ Online Seminar on Protein Calorimetry & Antibody Engineering ★ We will be holding an online seminar on "Antibody Engineering." We are pleased to welcome Dr. Nagamori from the University of Tokyo's Institute of Medical Science, who will present cutting-edge information on protein calorimetry and antibody engineering research. Additionally, we will provide information on instruments such as isothermal titration calorimeters (ITC) and differential scanning calorimeters (DSC) for biomacromolecules, and our group company Waters will introduce HPLC and UPLC technologies specialized for antibody analysis. Please feel free to join from your home or workplace. 【Participation Tool】Zoom *You can also participate via a web browser. (Participation is possible without downloading the Zoom application) Participation Fee: Free *Due to software specifications, there is a limit on the number of participants. Please register early. For details on the content and registration, please refer to the detailed page. We will notify you of the course details via email one week before the event.

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TA Instruments Japan (TAInstruments)

Testing, Analysis and Measurement

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TA Instruments Japan is a wholly-owned subsidiary of TA Instruments in Japan. We sell and provide maintenance support for thermal analysis, rheology, microcalorimeters, and mechanical analysis equipment, conduct demonstration measurements, and hold technical seminars, offering the latest information on materials and engaging in the development of measurement technologies for materials. 【Main Equipment Handled】 ☆ Thermal Analysis / Differential Scanning Calorimeter (DSC), Thermogravimetric Analyzer (TGA), Simultaneous Differential Thermal Analysis (SDT/TG-DTA), Vapor Adsorption/Desorption Analyzer (Q5000SA) ☆ Viscoelastic Measurement (Rheology) / Rotational Rheometer (DHR・ARES), Dynamic Mechanical Analyzer (RSA・DMA・EF3200), Rubber Testing Cure Meter (RPA) ☆ Microcalorimetry / Isothermal Titration Calorimeter (ITC), Microcalorimeter (NanoDSC), Isothermal Calorimeter (TAM) ☆ Thermal Property Measurement Equipment / Thermal Conductivity Meter (DTC・FOX), Thermal Diffusivity Meter (DLF, DXF), Thermal Expansion Meter (TMA, DIL), Optical Thermal Expansion Meter (ODP, HM) ☆ Fatigue Testing Machines / ElectroForce Series, BioDynamic Series

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