No pipetting operations are required during the experiment. It is equipped with a benchtop dispensing device that can automatically measure up to 48 cells continuously in an auto patch clamp system.
This is a tabletop-sized auto patch clamp system that can simultaneously measure up to 8 cells with giga-seal formation. With easy experimental setup, stable whole-cell recordings, and sophisticated software, it enables highly efficient compound ion channel screening. ■ Equipped with a dispensing device, allowing for fully automated experiments (measurements) ■ Simultaneous measurement of 4 cells / 8 cells (up to 48 cells can be measured continuously) ■ 250 to 600 data points per day ■ Automation from giga-seal formation to whole-cell formation ■ Compatible with voltage-dependent and ligand-dependent channels ■ Measurement of action potentials using current clamp is also possible ■ Dynamic clamp capability (optional) ■ Temperature control and extracellular/intracellular perfusion possible ■ Cooling plate allows for cooling of cells and compounds ■ Borosilicate glass chips reduce compound adsorption ■ Comes with excellent analysis software
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basic information
Measurement Performance ■ Accurate membrane potential stabilization ■ Application to primary cells ■ Inline heater integrated dispensing pipette ■ Fast solution exchange – short exposure to ligands ■ Automation of current clamp method, dynamic clamp ■ Intracellular perfusion Analysis Performance ■ Full dose/cell dose-response testing ■ Up to 100 dose-response curves per day (600 data points) ■ Analysis of up to 300 compounds per day ■ Batch analysis of multiple data files ■ Simple data analysis – only a few clicks
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Delivery Time
※The delivery date may vary depending on stock availability, so please feel free to contact us.
Applications/Examples of results
Since the product release in 2006, over 100 Patchliners have been implemented worldwide in universities (46%), pharmaceutical companies (34%), and CROs (20%). *For more details, please refer to the PDF document or feel free to contact us. For inquiries about the product, requests for demos, catalog requests, or any other inquiries, please feel free to contact us directly. Mail: info@nanion.jp
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Company information
Nanion Technologies is a scientific instrument manufacturer founded in 2002 in Munich, Germany, specializing in the automation of electrophysiology experiments. We enable the automation of electrophysiology experiments, supporting not only ion channel research but also a wide range of membrane protein-related studies. We offer a broad product lineup, including our industry-leading automated patch clamp system, transporter activity measurement systems, artificial lipid bilayer experimental devices, liposome production devices, and impedance, extracellular potential, and contraction force measurement systems for iPS-derived cardiomyocytes. These systems have been adopted by many universities, pharmaceutical companies, and research institutions both domestically and internationally, and are highly regarded. For inquiries about our products, requests for introductions, demo requests, or catalog requests, please contact us or our authorized distributors. Additionally, feel free to consult us about visiting our Tokyo lab (Meguro Ward) to see the systems and experiments. Mail: info@nanion.jp