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  6. 4ch/8ch Auto Patch Clamp Patchliner

4ch/8ch Auto Patch Clamp Patchliner

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Patchliner

last updated:Apr 30, 2025

ナニオンテクノロジーズジャパン 東京ラボ(東京大学内)
ナニオンテクノロジーズジャパン 東京ラボ(東京大学内)
  • Official site

No pipetting operations are required during the experiment. It is equipped with a benchtop dispensing device that can automatically measure up to 48 cells continuously in an auto patch clamp system.

This is a tabletop-sized auto patch clamp system that can simultaneously measure up to 8 cells with giga-seal formation. With easy experimental setup, stable whole-cell recordings, and sophisticated software, it enables highly efficient compound ion channel screening. ■ Equipped with a dispensing device, allowing for fully automated experiments (measurements) ■ Simultaneous measurement of 4 cells / 8 cells (up to 48 cells can be measured continuously) ■ 250 to 600 data points per day ■ Automation from giga-seal formation to whole-cell formation ■ Compatible with voltage-dependent and ligand-dependent channels ■ Measurement of action potentials using current clamp is also possible ■ Dynamic clamp capability (optional) ■ Temperature control and extracellular/intracellular perfusion possible ■ Cooling plate allows for cooling of cells and compounds ■ Borosilicate glass chips reduce compound adsorption ■ Comes with excellent analysis software

    Other physicochemical equipmentAnalytical EquipmentPatch clamp system
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4ch/8ch Auto Patch Clamp Patchliner

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PL.jpg
  • Related Link - https://www.youtube.com/watch?v=Nj6C7FYXNbw

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basic information

Measurement Performance ■ Accurate membrane potential stabilization ■ Application to primary cells ■ Inline heater integrated dispensing pipette ■ Fast solution exchange – short exposure to ligands ■ Automation of current clamp method, dynamic clamp ■ Intracellular perfusion Analysis Performance ■ Full dose/cell dose-response testing ■ Up to 100 dose-response curves per day (600 data points) ■ Analysis of up to 300 compounds per day ■ Batch analysis of multiple data files ■ Simple data analysis – only a few clicks

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Applications/Examples of results

Since the product release in 2006, over 100 Patchliners have been implemented worldwide in universities (46%), pharmaceutical companies (34%), and CROs (20%). *For more details, please refer to the PDF document or feel free to contact us. For inquiries about the product, requests for demos, catalog requests, or any other inquiries, please feel free to contact us directly. Mail: info@nanion.jp

catalog(14)

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Comprehensive Catalog: Electrophysiology Experimental Equipment Catalog vol. 6

Comprehensive Catalog: Electrophysiology Experimental Equipment Catalog vol. 6

CATALOG
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4ch/8ch Auto Patch Clamp System Patchliner

4ch/8ch Auto Patch Clamp System Patchliner

PRODUCT
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【Cell and Ion Channel Measurement Example】 Auto Patch Clamp System

【Cell and Ion Channel Measurement Example】 Auto Patch Clamp System

TECHNICAL
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[Measurement Example] Nav1.8 | Patchliner

[Measurement Example] Nav1.8 | Patchliner

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[Measurement Example] DRG Neurons | Patchliner

[Measurement Example] DRG Neurons | Patchliner

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[Measurement Example] NaV1.5 | Patchliner

[Measurement Example] NaV1.5 | Patchliner

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[Measurement Example] Dynamic Clamp | Patchliner

[Measurement Example] Dynamic Clamp | Patchliner

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[Measurement Example] TRPV3 | Patchliner

[Measurement Example] TRPV3 | Patchliner

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[Measurement Example] nAChR | Patchliner

[Measurement Example] nAChR | Patchliner

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[Measurement Example] AMPA | Patchliner

[Measurement Example] AMPA | Patchliner

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[Measurement Example] PIEZO1 | Patchliner

[Measurement Example] PIEZO1 | Patchliner

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[Measurement Example] P2X | Patchliner

[Measurement Example] P2X | Patchliner

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[Measurement Example] hERG | Patchliner

[Measurement Example] hERG | Patchliner

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Differences between Auto and Manual Patch Clamp

Differences between Auto and Manual Patch Clamp

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News about this product(18)

[Workshop Announcement] Electrophysiology Experiment Workshop 2025

  • Seminar・Event

You can experience actual measurements and demonstrations using our various products. For more details about the products, please refer to the related products below. *Capacity: Approximately 10 to 20 people *Due to limited lab space, depending on the number of participants, there may be a possibility of dividing into two sessions, morning and afternoon. *Participants who register for the workshop will be contacted again once the details are finalized.

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[Seminar Announcement] Membrane Physiology Symposium Japan 2025

  • Seminar・Event

We are pleased to announce that Nanion Technologies Japan Co., Ltd. will co-host the Membrane Physiology Symposium Japan 2025 in collaboration with Professor Hideaki Kato's laboratory at the University of Tokyo's Advanced Research Center. Following the symposium, we will also hold a modest networking event, and we warmly invite you to participate. For details on the program and other information, please refer to the related PDF documents. Speakers (in alphabetical order): - Dr. Kenji Akiyoshi | Keio University, Faculty of Pharmacy - Dr. Shuutarou Katsurabayashi | Fukuoka University, Faculty of Pharmacy - Dr. Hideaki Kato | University of Tokyo, Advanced Research Center - Dr. Tomoya Kubota | Osaka University Graduate School of Medicine - Dr. Shin Hamamoto | University of Tokyo Graduate School of Agricultural and Life Sciences - Dr. Yuichiro Miyaoka | Tokyo Metropolitan Institute of Medical Science - Dr. Chai-Ann Ng | Victor Chang Cardiac Research Institute - Dr. Alexandre Santinho | Oria Bioscience - Dr. Will Seibertz | Nanion Technologies GmbH - Dr. Martin Ziller | Nanion Technologies GmbH

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[Seminar Announcement] Ion Channel Forum 2023

  • Seminar・Event

We are pleased to announce that Nanion Technologies Japan Co., Ltd. will be hosting the Ion Channel Forum 2023 in person for the first time in four years, in collaboration with Tokyo Women's Medical University. Following the forum, we will hold a modest networking event at a hotel in Tokyo. Additionally, we plan to conduct a workshop on electrophysiology using our various products the following day. Scheduled speakers (in alphabetical order): Dr. Tadashi Kimura | Veneno Technologies Co., Ltd. Dr. Takaaki Sogabe | Center for Life Creation Research, Temperature Biology Research Group Dr. Kiyoshi Takasago, Dr. Hatsue Furukawa | Axcelead Drug Discovery Partners, Inc. Dr. Takuma Takada | Advanced Research Institute for Medical Science, Tokyo Women's Medical University Dr. Hiroyuki Takeda | ProteoScience Center, Ehime University, Department of Proteo-Drug Discovery Science Dr. Tomoya Tsukazaki | Nara Institute of Science and Technology, Graduate School of Advanced Science and Technology, Bioscience Area, Structural Life Science Dr. Masafumi Doi | Daiichi Sankyo RD Novare Co., Ltd., Biological Evaluation Research Department, Discovery ADMET Group

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Announcement of Catalog Publication: Electrophysiology Experimental Equipment Catalog vol. 6

  • Catalog news

We are pleased to announce the publication of the Electrophysiology Experimental Equipment Catalog vol. 6. 【Featured Products in the Catalog】 ■ Auto Patch Clamp System Ideal for evaluating the effects of compounds on ion channels and for functional and structural analysis of ion channels. From a compact system that allows you to check data immediately at hand to a high-throughput system for compound screening in pharmaceutical research and development. ■ Artificial Lipid Bilayer Experimental Device For functional and structural evaluation of target membrane proteins reconstituted into artificial lipid bilayers, as well as for evaluating drug actions. ■ Liposome Preparation Device Quickly and easily automates the preparation of liposomes without hassle. ■ Transporter Activity Measurement Device Enables label-free and real-time direct measurement of transporter currents without using fluorescent probes or radiolabeled ligands. ■ iPS-Derived Cardiomyocyte Measurement System For evaluating cardiotoxicity, contractility, and drug screening using iPS-derived cardiomyocytes. ■ Cell Monitoring Device Allows for label-free and real-time high-throughput measurement of cell kinetics (up to 6 x 96-well plates).

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Company information

ナニオンテクノロジーズジャパン

ナニオンテクノロジーズジャパン 東京ラボ(東京大学内)

Pharmaceuticals and Biotechnology

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Phone number/address

Nanion Technologies is a scientific instrument manufacturer founded in 2002 in Munich, Germany, specializing in the automation of electrophysiology experiments. We enable the automation of electrophysiology experiments, supporting not only ion channel research but also a wide range of membrane protein-related studies. We offer a broad product lineup, including our industry-leading automated patch clamp system, transporter activity measurement systems, artificial lipid bilayer experimental devices, liposome production devices, and impedance, extracellular potential, and contraction force measurement systems for iPS-derived cardiomyocytes. These systems have been adopted by many universities, pharmaceutical companies, and research institutions both domestically and internationally, and are highly regarded. For inquiries about our products, requests for introductions, demo requests, or catalog requests, please contact us or our authorized distributors. Additionally, feel free to consult us about visiting our Tokyo lab (Meguro Ward) to see the systems and experiments. Mail: info@nanion.jp

Product/Service List (49)

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  • Analytical Equipment
          

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