It is possible to carefully select candidate compounds for wet screening! English version catalog available!
"INTENDD" is an in silico technology based on a concept different from the commonly used MD calculation-based docking methods. It demonstrates high performance in drug discovery research targeting protein-protein interactions (PPI). This is our proprietary in silico drug discovery technology, capable of narrowing down from a library of ten million compounds to about 200 hit candidate compounds. [Features] ■ Maximizes the success rate of small molecule drug discovery research ■ Creation of diverse compounds with unique scaffolds ■ Accurate activity prediction at the nanomolar level ■ Hit rate of up to 20% ■ Expansion of collaborative research opportunities * You can download the English version of the catalog. * For more details, please refer to the PDF materials or feel free to contact us.
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basic information
【Other Features】 ■ It is possible to carefully select candidate compounds for wet screening. ■ Based on a unique technological foundation, compounds with multiple unique structures are identified according to their binding mechanisms. ■ Using a unique technological foundation, compounds with high entropy activity are extracted. ■ Activity predictions are made considering that entropy accounts for about one-third of the total binding energy. ■ It is possible to obtain hit compounds with approximately 20% probability in the 1st screening and about 50% probability in the 2nd screening after extracting related compounds. ■ Different technologies can complement each other's weaknesses, resulting in more powerful outcomes. * You can download the English version of the catalog. * For more details, please refer to the PDF materials or feel free to contact us.
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*You can download the English version of the catalog. *For more details, please refer to the PDF document or feel free to contact us.
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Our company has the management philosophy of "contributing to the health and welfare of humanity by supplying pharmaceuticals to patients around the world" and aims to create "innovative, versatile pharmaceuticals that minimize the burden of medical expenses from the patient's perspective" as our management vision. We operate in two main areas: our core business of "drug discovery" and the "consulting business related to drug discovery," which handles advisory services such as business development and research and development.
