【Technology and Achievements Introduction】Solid form technology

We can also propose developed crystalline forms according to your requests! Introducing our active pharmaceutical ingredient crystallization technology!

The selection of the solid form of the active pharmaceutical ingredient is an essential process that cannot be avoided in the drug development process. To crystallize compounds that are difficult to crystallize, obtain solid forms with better physical properties, and comprehensively investigate polymorphism, it is necessary to examine crystallization under various conditions. At SpiraPharma, we conduct studies focused on primary nucleation using a well-plate type high-throughput device. Additionally, in cases where a mixture of polymorphs is likely to occur, we add the obtained seed crystals to each crystallization condition and use the competitive slurry conversion method to achieve a single crystal form. Furthermore, we can provide physical property evaluations, confirm thermodynamically stable crystal forms, and propose developed crystal forms according to your requests. 【Features】 ■ Conduct studies specialized in primary nucleation ■ Possible to propose developed crystal forms based on physical property evaluations and confirmation of thermodynamically stable crystal forms *For more details, please refer to the PDF document or feel free to contact us.

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