I have summarized the challenges and solutions for nitrosamine analysis.

As the second installment of the highly acclaimed webinar "Latest Information on Nitrosamine Analysis" held in June last year, we will be hosting an online seminar that focuses on more practical analytical approaches and content directly related to quality control. In this webinar, we will discuss the latest application examples of nitrosamine analysis using the Agilent 6495D LC/TQ, as well as key points regarding data integrity, which has become increasingly important in the pharmaceutical industry. The content is designed to be immediately applicable to the work of those engaged in enhancing the sophistication and reliability of nitrosamine analysis. Target Audience - Pharmaceutical manufacturers considering or conducting nitrosamine analysis - Analysts and lab managers from contract analysis organizations Program - Introduction to the latest nitrosamine analysis techniques using LC/MS - Data integrity required for pharmaceutical impurity analysis

<June 21 (Wednesday) Special Lecture on Oligonucleotides> "Analysis of Impurities in Oligonucleotide Manufacturing" The techniques of HPLC and LC/MS have improved in recent years and have become essential methods for the analysis of oligonucleotides. This presentation will introduce examples of oligonucleotide analysis using 2D-LC/MS and the results of comparisons of the columns used for analysis. Ajinomoto Bio-Pharma Services Ms. Emi Saito, Research and Development Department, GeneDesign Inc. <Program> 1. [Special Lecture] Analysis of Impurities in Oligonucleotide Manufacturing 2. Oligonucleotide Purification 3. Automation and Labor-Saving of Oligonucleotide Analysis using 2D-LC/MS 4. Agilent's Enterprise & Consulting Services

<Special Lecture on Antibody Drugs and ADC> Ms. Eriko Numao, Kyowa Kirin Co., Ltd. "New Performance Evaluation Method of Multi-Attribute Method and Future Prospects: From Manufacturing Considerations to Quality Control" This presentation will introduce the results and challenges of performance evaluation using a new method of the Multi-Attribute Method, which has recently gained attention as a new tool for quality evaluation of biopharmaceuticals, as well as future prospects. ---------------- We will hold a three-part webinar series covering analysis fundamentals to applications, divided by modality. <Day 1. Program> Special Lecture "New Performance Evaluation Method of Multi-Attribute Method and Future Prospects: From Manufacturing Considerations to Quality Control" Ms. Eriko Numao, Kyowa Kirin Co., Ltd. Bioproduct Technology Research Institute "End-to-End Workflow for Characterization of Antibody Drugs and ADCs" "Case Studies of HPLC Columns and Multidimensional HPLC Applications for Antibody Drugs" "Automation of Antibody Preprocessing Using Dispensing Machines" "Proposal for Lab DX and Data Integrity Compliance" Agilent Technologies

Establishing a method to accurately analyze nitrosamine impurities, which are carcinogenic substances, is an important challenge. This demonstrates a method for detecting nitrosamines specified by organizations such as the Pharmaceuticals and Medical Devices Agency (PMDA) using Agilent's LC/MS and GC/MS.