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  6. New Technology: Flow Chemistry

New Technology: Flow Chemistry

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last updated:Jul 30, 2024

日本理化学工業
日本理化学工業
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Would you like to try a reaction that cannot be done in a reaction vessel?

Research Scale YMC-made microreactor (two-liquid mixing, hydrogenation reaction, photoreaction) Saida FDS-made microwave flow reaction device Pilot Scale Nakamura Super Hard-made flow-type two-liquid reaction system (Hastelloy) Manufacturing Scale Kobe Steel-made stacked multi-channel reactor (SMCR)

    Chemicals
フローニトロ化01.jpg

New Technology: Flow Chemistry

フローニトロ化01.jpg
フローニトロ化01.jpg
  • Related Link - https://www.nichiri.co.jp/

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1. Saida FDS manufactured microwave flow reaction device Microwave oscillator output: maximum 100W Maximum reaction temperature: 230 ℃ Maximum pressure: 2.5 MPa Maximum liquid delivery rate: 20 mL/min Reaction tube volume: 1.0 to 3.8 mL 2. Nakamura Super Hard manufactured flow-type two-liquid reaction system (Hastelloy) Flow path: made of Hastelloy Acid pump: made of Hastelloy Normal liquid pump: made of SUS 16 Flow path shape: circular, Φ6.35mm, inner diameter 4.35mm Reaction chamber volume: 212.5 mL Design temperature: 200 ℃ Design maximum pressure: 13 MPa Maximum flow rate of acid pump: 150 mL/min Maximum flow rate of normal liquid pump: 150 mL/min 3. Kobe Steel manufactured stacked multi-channel reactor (SMCR) Made of SUS316 440W × 900L × 275H (mm) Empty weight: 760 kg Flow path shape: circular, Φ2.0mm Flow path length: 20m Number of flow paths: 144 Flow path volume: 9.0L Design temperature: -70℃ to 180℃

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1. Saida FDS manufactured microwave flow reaction device Equipped with multiple reaction tubes such as straight tubes and spiral tubes Reactions can also be conducted using 1/16 inch PTFE tubes Use of reaction tubes filled with solid catalysts is also possible 2. Nakamura Super Hard manufactured flow-type two-liquid reaction system (Hastelloy) Usable for acid-based reactions (nitrate and sulfuric acid can be used) 3. Kobe Steel manufactured stacked multi-channel reactor (SMCR) Capable of low-temperature reactions (production record at -50°C)

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日本理化学工業

日本理化学工業

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Our company was established in 1919 with the corporate philosophy of "contributing to society through chemistry that connects the flask to the plant." We have repeatedly engaged in the research and development of pharmaceutical intermediates, built our unique synthesis technology, and provided high-quality, custom-made products to meet our customers' needs as a research and development-oriented company. Moving forward, we will continue to base our business on fine chemicals, accelerate our efforts in the research and development of pharmaceutical intermediates, and promote the research and development of distinctive organic compounds by introducing new technologies.

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