Optimization of CHO cell culture process based on DOE in Ambr15.

This webinar will focus on perfusion culture, which is gaining attention for process enhancement, and will introduce examples of utilizing Sartorius solutions. The bioreactors Ambr 15, Ambr 250 HT, and Biostat STR are compatible with perfusion culture. This time, we will explain the mechanisms and operational methods using Ambr 15 and Ambr 250 HT. Additionally, our CHO cell line development service utilizes the 4Cell SmartCHO medium, which can accommodate both fed-batch and perfusion cultures, and can also be used for suitable clone selection. Through examples that combine Ambr 15 and Ambr 250 HT with the same medium, we will convey the image of its application in process development. 【Seminar Overview】 ▪ Date: July 16 (Thursday) from 15:00 (approximately 30 minutes) ▪ Format: Webinar recorded broadcast [Japanese, Free] If you are unable to participate on the day, please register first. We will send you a URL for viewing later. *We kindly ask that participants refrain from registering with email addresses other than those from your own company or organization. Thank you for your understanding.

The Ambr 250 High Throughput is a high-throughput bioreactor that accelerates process development and process characterization analysis. It enables simultaneous cultivation of up to 24 samples while incorporating automated control via a robotic arm and integration with external analytical devices. The culture containers are single-use specifications of 100-250 mL and are compatible with perfusion culture and microcarrier culture. This device has been enhanced based on customer feedback and was launched as the second generation, Ambr 250 High Throughput Generation 2, starting in 2025 to demonstrate further performance as a scale-down model. In this webinar, we will introduce the device overview and the enhanced features in Generation 2. 【Seminar Overview】 ▪ Date: October 16 (Thursday) at 15:00 (approximately 30 minutes) ▪ Method: Webinar recorded broadcast [Japanese, Free] *We apologize, but participation from companies in the same industry and email addresses other than those of your organization is not permitted. Thank you for your understanding.

We will be exhibiting and presenting a luncheon seminar at BioJapan 2025, which will be held at Pacifico Yokohama from October 8 to 10, 2025. At our booth, we will introduce our cell line development services and media optimization services that achieve a scalable fed-batch process with a monoclonal antibody titer of up to 10 g/L in just 9 weeks, from DNA to RCB. We will also showcase single-use culture vessels for process development. In addition, during the luncheon seminar, we will provide a clear overview of Sartorius' CLD services, making it easy to understand for those who are new to the topic. If you are considering shortening timelines, optimizing product quality, or exploring flexible development strategies, please join us. We look forward to seeing you there. Event Overview: October 8 (Wed) - 10 (Fri), 2025, Pacifico Yokohama Exhibition Booth: Small Booth Number D-109 Luncheon Seminar: Title: Minimizing Risks in CHO Cell Line Development through Automation and Predictive Models Seminar Date and Time: October 9 (Thu) 11:30 AM - 12:30 PM