Olink Target 48 Neurodegenerative Diseases
Olink Proteomics Target 48 Neurodegeneration
Research on neurodegenerative diseases using PEA technology, pioneering with the latest markers and absolute quantification.
Olink Target 48 Neurodegeneration is a high-performance proteomics panel specialized in neurodegenerative disease research. It can simultaneously measure 41 types of proteins, including the latest and important central nervous system biomarkers such as Aß40, Aß42, pTau217, NfL, and GFAP, which are gaining attention in Alzheimer's and Parkinson's disease research. This panel enables the acquisition of absolute quantification (ng/mL) data, which is difficult with other technologies, allowing for data comparison between studies and institutions, as well as high reproducibility in long-term longitudinal studies. With just 1µL of plasma or cerebrospinal fluid, high-sensitivity measurements can be achieved, maximizing the use of valuable clinical samples. Furthermore, by combining analyses with Olink's cytokine panel, it comprehensively captures neurodegeneration and neuroinflammation, significantly enhancing analytical power. The standardized workflow using the Signature Q100 system contributes broadly from basic research to clinical and drug discovery research.
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basic information
Number of proteins: 41 (verified) Sample volume: 1 µL (plasma, serum, etc.) / panel Specificity: 99.5% (minimal cross-reactivity) Expression value: pg/mL absolute quantification Reading: quantitative PCR (Olink Signature Q100)
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- Researchers in neurobiology, neuropathology, and biomarker studies at universities and research institutions. Involved in the translational research departments and clinical development departments of pharmaceutical and biotechnology companies. - Research utilization for the exploration of early diagnostic markers for diseases, assessment of disease progression, patient stratification, and monitoring of treatment effects. - Provides highly reproducible quantitative data, making it easy to compare between studies, and is therefore used in longitudinal studies and large cohort studies.
Detailed information
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PEA technology is an application that can provide data close to true biology with high specificity and sensitivity. The target panel is read using quantitative PCR, allowing for absolute quantification.
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Thermo Fisher Scientific K.K., the Japanese subsidiary of Thermo Fisher Scientific Incorporated, is a sales company for comprehensive system analysis instruments, bio-related equipment, and research reagents. In Japan, it has bases in Yokohama, Tokyo, Osaka, Fukuoka, and Nagoya, handling various analytical instruments including mass spectrometers, various bio-related equipment, measuring instruments, medical devices, lab software, and research reagents.
