We have compiled a list of manufacturers, distributors, product information, reference prices, and rankings for HPLC columns.
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HPLC columns Product List and Ranking from 11 Manufacturers, Suppliers and Companies | IPROS GMS

Last Updated: Aggregation Period:Mar 04, 2026~Mar 31, 2026
This ranking is based on the number of page views on our site.

HPLC columns Manufacturer, Suppliers and Company Rankings

Last Updated: Aggregation Period:Mar 04, 2026~Mar 31, 2026
This ranking is based on the number of page views on our site.

  1. 東ソー バイオサイエンス事業部 計測分野 Tokyo//Chemical
  2. ADSTEC Corporation Bio Department Chiba//others
  3. メルク株式会社ライフサイエンス(シグマ アルドリッチ ジャパン合同会社) Tokyo//Testing, Analysis and Measurement
  4. 4 サーモフィッシャーサイエンティフィック株式会社/Thermo Fisher Scientific K.K. Tokyo//Testing, Analysis and Measurement
  5. 5 日本ウォーターズ(米国本社 Waters Corporation)  Tokyo//Testing, Analysis and Measurement

HPLC columns Product ranking

Last Updated: Aggregation Period:Mar 04, 2026~Mar 31, 2026
This ranking is based on the number of page views on our site.

  1. HPLC Column "GPC Column - Molecular Weight Marker" 東ソー バイオサイエンス事業部 計測分野
  2. HPLC column "Ion Chromatography" 東ソー バイオサイエンス事業部 計測分野
  3. HPLC column 日本ウォーターズ(米国本社 Waters Corporation) 
  4. HPLC column "Size Exclusion Chromatography" 東ソー バイオサイエンス事業部 計測分野
  5. 4 [Data] RP-Amide HPLC/UHPLC Column メルク株式会社ライフサイエンス(シグマ アルドリッチ ジャパン合同会社)

HPLC columns Product List

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HPLC column "Supel Carbon LC"

Usable at 11,500 psi! Porous graphite carbon HPLC column

"Supel Carbon LC" is a porous graphite carbon HPLC column suitable for the separation of water-soluble analog compounds. The maximum operating temperature is 250°C, and it is compatible with pH 1 to 14. It is effective for the separation of hydrophilic analog compounds. Patented porous graphite carbon (PGC) particles are used as the packing material. 【Features】 ■ For the separation of water-soluble analog compounds ■ Can be backwashed ■ Compatible with pH 1 to 14 ■ Maximum operating temperature of 250°C ■ Usable at 11,500 psi (800 bar) *For more details, please refer to the PDF document or feel free to contact us.

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[Data] Fully porous 3.5μm HPLC column

Ascentis and Discovery: A rich lineup of stationary phases!

This document introduces the "Ascentis and Discovery All-Porous 3.5μm HPLC Columns." It includes a stationary phase selection guide, usage guide, measurement examples, and a list of HPLC column products. Explanations are provided along with graphs and photos, so please take a moment to read it. [Contents] ■ Stationary Phase Selection Guide ■ Usage Guide ■ Measurement Examples ■ HPLC Column Product List *For more details, please refer to the PDF document or feel free to contact us.

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HPLC column

A lineup of HPLC columns that achieves outstanding chromatography.

Waters is developing a business based on chromatography. It is our customers who utilize this chromatography technology in their businesses. The innovative insights in your labs lead to the establishment of analytical/testing methods that contribute to business success. Our customers' "success" can be evaluated by continuously monitoring analytical methods and results, and it is essential that the chosen columns remain available for you to continue achieving "success" in the future. Many customers who fully understand the impact of column performance and innovation on "success" have chosen Waters' cutting-edge reversed-phase and HILIC HPLC column products. 【Features】 - Synthesis of silica and hybrid materials conducted in-house: Latest technology can be applied to particles. - All latest chromatography packing materials are consistently managed from starting monomers to final products. - Manufacturing facilities are certified cGMP, ISO9001, and ISO13485: Establishing analytical reliability through stringent quality control systems. - Most column hardware is also manufactured in-house from raw materials. - As a global company, we provide products of the same quality in countries around the world.

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ZORBAX Original Reverse Phase HPLC Column

It has a high activity level and helps in the separation of isomers and the improvement of selectivity!

We would like to introduce the "ZORBAX Original Reverse Phase HPLC Column" that we handle. Our lineup includes "ZORBAX C18," "ZORBAX C8," "ZORBAX-Phenyl," and others. These columns are manufactured using Type A silica and are useful for the separation of acidic or neutral compounds. Please feel free to consult us when you need assistance. 【ZORBAX C18 Specifications】 ■ZORBAX C18 - Pore Size: 70A - Surface Area: 300m²/g - Temperature Range: 60℃ - pH Range: 2.0-8.0 - End Cap: Yes - Carbon Content: 20% *For more details, please refer to the PDF document or feel free to contact us.

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PLRP-S for biomolecules

Chemically and physically stable and robust! LC column for biopharmaceutical analysis.

"PLRP-S for Biomolecules" is an HPLC column filled with macroporous styrene-divinylbenzene. It is a highly reproducible reverse-phase HPLC column, and there is no need for the attachment of alkyl chains (such as C18 or C8) to enhance hydrophobicity. Additionally, the surface of PLRP-S has no unnecessary activity, so there is no occurrence of separation inconsistency due to residual silanol or end-capping rates seen in silica-based fillers. 【Features (Specifications)】 ■ Polymer: Macroporous spherical styrene-divinylbenzene ■ Particle sizes: 3μm, 5μm, 8μm, 10μm, 30μm ■ Pore sizes: 100Å, 300Å, 1000Å, 4000Å ■ Functional groups: None ■ Usable organic solvent concentration: 1–100% (100% water is not allowed) *For more details, please refer to the related links or feel free to contact us.

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VariTide RPC

Developing a polymer-based HPLC column to economically enhance throughput and analyze and purify synthetic peptides!

We would like to introduce our LC column for biopharmaceutical analysis, 'VariTide RPC.' To efficiently retain peptides composed of 5 to 60 amino acids, we adjust the particle size and pore size. It can be used at various pH ranges, allowing for the separation and purification of acidic, basic, hydrophilic, and hydrophobic peptides with this product. 【Features (Specifications)】 ■ Polymer: Macroporous spherical styrene-divinylbenzene ■ Particle size: 6μm ■ Pore diameter: 200Å ■ Functional groups: None ■ Column size: Inner diameter: 4.6mm to 21.2mm / Length: 25cm *For more details, please refer to the related links or feel free to contact us.

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Biomonolith

Designed for the separation of macromolecular biomolecules! Polymer-based monolith HPLC column.

We would like to introduce our bio-pharmaceutical analysis LC column, "Bio Monolith." It enables high-speed, high-resolution separation of antibodies (IgG, IgM), plasmid DNA, viruses, phages, and other macro biomolecules. Strong cation exchange phases, strong and weak anion exchange phases, and Protein A phases are available. It is compatible with HPLC and preparative LC systems such as the "1200 Infinity Series," as well as HPLC systems from other manufacturers. 【Features】 ■ Separation unaffected by flow rate ■ High-speed movement between the mobile phase and stationary phase ■ Ultra-fast separation ■ Accelerates method development and reduces costs by fixing method parameters *For more details, please refer to the related links or feel free to contact us.

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HPLC column "SunArmor"

Further evolution of surface treatment! HPLC columns that achieve astonishing alkali resistance.

"SunArmor" is an HPLC column that achieves remarkable alkali resistance while being silica gel particles, thanks to the newly developed silylation agent and TMS for final end-capping, in addition to the conventional Sunniest end-capping. The usable pH range of the mobile phase with the C18 stationary phase is from 2 to 12, providing durability equivalent to hybrid silica. A high-durability NH2 column has been added. 【Features】 ○ Superior alkali resistance compared to other hybrid C18 columns ○ Not affected by residual silanol groups ○ Exhibits good peak shapes for acidic, basic, and metal-coordinating compounds For more details, please contact us or download the catalog.

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Reversed-phase HPLC column "Sunrise C18-SAC"

The reversed-phase HPLC column chemically modified with silanol groups is abbreviated as SAC, which stands for Silanol Activity Control.

The "Sunrise C18-SAC" is an HPLC column that intentionally does not use end-capping, utilizing the properties of residual silanol groups to bond C18. Thanks to silanol activity control technology, it achieves peaks of basic compounds without tailing, even without end-capping. The unique selectivity provided by the regulated silanol groups allows for separations that cannot be achieved with conventional C18 columns. [C18-SAC Octadecyl-SAC] ○ A "2nd Choice" column with effective residual silanol For more details, please contact us or download the catalog.

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Ultra Hybrid UHPLC/HPLC Column

Durability and inertness that surpass conventional hybrid C18.

SunBridge is an all-porous hybrid column with unprecedented stability. Thanks to the fusion technology of silica surface treatment and the creation of organic silica particles (Ultra Hybrid Technology) that our company has developed since its founding, it exhibits extremely high durability and stability that surpasses the limits of conventional C18 columns. ★ Mobile phases from pH 1 to pH 12 can be used ★ Good peak shape for acidic, basic, and metal-coordinating compounds ★ A 40% discount campaign sale will be held from February 2025 to the end of July 2025 ★ Particle sizes of 3 µm and 1.8 µm are scheduled to be launched in the spring and summer of 2025

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HPLC Column "GPC Column - Molecular Weight Marker"

Introducing a wide range of products, including semi-micro SEC columns with a high degree of pore dispersion.

In addition to general-purpose GPC columns, we also introduce specialized SEC columns such as the ultra-fast SEC columns "SuperHZ Series" and "HXL Series," along with guidance on how to differentiate between SEC columns. 【Features】 <SuperMultiporeHZ Series> ■ Pore size-distributed semi-micro SEC column ■ Excellent linearity of calibration curves ■ No inflection points, resulting in undistorted chromatograms ■ Three grades available with different molecular weight fraction ranges *For more details, please refer to the PDF materials or feel free to contact us.

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ACE SuperC18 UHPLC & HPLC Column

SuperC18 UHPLC/HPLC column with expanded pH range due to unique encapsulation technology.

The ACE SuperC18 column is a UHPLC/HPLC column that expands the usable pH range (pH 1.5 to 11.5) compared to conventional C18 columns, thanks to the unique EBT technology (Encapsulated Bonding Technology) developed by ACT (Advanced Chromatography Technologies). The unique EBT technology dramatically increases the ligand coverage on the silica surface, eliminating the influence of unbound silanols, thereby enhancing inertness and stability. It is also designed for use with LC-MS buffers, providing ultra-low bleed to improve compatibility with LC-MS. It can be used with both methanol and acetonitrile as mobile phases, offering rapid column equilibration without memory effects. **Features** - Selectivity changes are available (in low, medium, and high pH ranges) - Excellent column life reduces costs - Usable with LC/MS compatible buffers - Recommended pH range: 1.5 to 11.5 - Compatibility with both methanol and acetonitrile - Fast column equilibration without memory effects

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Just 5 minutes of high-speed reverse-phase chiral separation ULTRON ES-OVM-3

Achieving ultra-fast chiral analysis using reverse-phase HPLC.

ULTRON ES-OVM-3 accelerates chiral separation and analysis using reverse-phase HPLC, a feature of ULTRON ES-OVM. It utilizes ovalbumin, an egg white protein, as a chiral recognition ligand, allowing for the chiral identification of many pharmaceuticals that dock with proteins. Chiral analysis of many pharmaceuticals, starting with Clopidogrel bisulfate, which utilizes ULTRON ES-OVM (USP L57), can be completed in 5 to 10 minutes. The following pharmaceuticals undergo ultra-fast reverse-phase chiral analysis in just under 5 minutes. For more details, please contact our company or your representative. - Clopidogrel bisulfate - Amlodipine - Atomoxetine hydrochloride - Carvedilol - Duloxetine hydrochloride - Tolperisone hydrochloride - Tolterodine

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Technical Data: Chiral Column for Reverse Phase Ultron ES-OVM

Effective for metabolic studies in blood! A column that is valuable in the fields of pharmaceuticals, pesticides, food, and organic synthesis.

The "Ultron ES-OVM" is an optical separation HPLC column that has many excellent features, such as being easy to use in reverse phase mode, having good peak shape, and being suitable for the study of trace metabolites. It uses amino-modified silica gel with proteins that are resistant to denaturation as the stationary phase, allowing for the analysis of plasma samples without any pre-treatment. This document includes the basic properties of the ligand, examples of separation degree adjustment, and case studies of compound analysis using the Ultron ES-OVM. We encourage you to read it. [Contents] ■ Basic properties of the ligand ■ Mechanism of separation ■ Selection of mobile phase ■ Relationship between pH and capacity factor ■ Relationship between salt concentration and capacity factor *For more details, please refer to the PDF document or feel free to contact us.

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Oligo analysis HPLC column OligoSep Cartridge

High-performance liquid chromatography (HPLC) column for oligonucleotide analysis

The OligoSep Cartridge manufactured by ADS Biotec (formerly Transgenomic) is a column for oligonucleotide analysis using ion-pair reverse phase HPLC. The packing material consists of non-porous beads made of alkylated polystyrene-divinylbenzene. Due to the non-porous nature of the beads, it allows for higher precision purification. It can be used not only for quality control of oligonucleotides but also for high-precision analysis of both single-stranded and double-stranded DNA. It is compatible with various types of high-performance liquid chromatography (HPLC) systems. By using buffers manufactured by ADS Biotec as the mobile phase, high-precision separation can be achieved. Additionally, by following the procedures outlined in the instruction manual to wash the column with 75% acetonitrile, the column can be reused multiple times.

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HPLC column for oligonucleotide HPLC purification - OligoSep Prep HC Cartridge

High-performance liquid chromatography (HPLC) column for the purification of synthetic oligonucleotides.

The OligoSep Prep HC Cartridge manufactured by ADS Biotec (formerly Transgenomic) is a column for the purification of oligonucleotides using ion-pair reverse phase HPLC. It uses porous beads made of alkylated polystyrene-divinylbenzene (PS-DVB). Due to the porous nature of the beads, the surface area is increased, allowing for the purification of larger amounts of samples. It can be used for the purification of synthetic oligos. It is compatible with various types of high-performance liquid chromatography (HPLC) systems. By using ADS Biotec's buffer as the mobile phase, high-precision separation can be achieved. Additionally, by following the procedures outlined in the instruction manual and washing the column with 75% acetonitrile, the column can be reused multiple times.

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Application Note: HPLC Products for Oligonucleotide Analysis

HPLC column and buffer for oligonucleotide analysis

The HPLC columns and buffers for oligonucleotide analysis manufactured by ADS Biotec in the United States use beads made of alkylated polystyrene-divinylbenzene. The columns are referred to as the OligoSep series. Oligonucleotides are used in research for antisense and siRNA pharmaceuticals.

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mRNA analysis HPLC products RNASep series

Capable of handling everything from mRNA analysis to purification! RNASep series

The RNASep series from ADS Biotec in the United States is capable of handling everything from mRNA analysis to purification.

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HPLC column for optical isomer separation

HPLC column for optical isomer separation

Optical isomers present in various bioactive substances (such as pharmaceuticals, pesticides, and fragrances) that are deeply related to our daily lives are known to exhibit significantly different biological activities between isomers, increasing the necessity for the analysis and separation of optical isomers. The "SUMICHIRAL OA series" HPLC columns for the separation of optical isomers are gaining attention in fields such as pharmaceuticals and pesticides.

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F5 (PFP) HPLC/UHPLC column

Separation of positional isomers using reverse phase and HILIC analysis! An additional step to add to C18 and HILIC columns.

The "F5 (PFP) HPLC/UHPLC column" for metabolomics is a reversed-phase column with selectivity different from C18. By incorporating it as a second or third choice column in reversed-phase systems, the range of substances for LC analysis is broadened. Four retention mechanisms—hydrogen bonding, dipole-dipole interactions, π-π interactions, and hydrophobic interactions—complexly influence each other to exhibit unique retention characteristics and stereoselectivity. 【Features】 ■ Retains highly polar basic compounds without ion-pair reagents ■ 100% water mobile phase is usable ■ Suitable for LC/MS due to retention at high organic solvent concentrations ■ Supports both analysis and fractionation *For more details, please refer to the PDF document or feel free to contact us.

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Ascentis Express HILIC Guide

Retention and separation of hydrophilic compounds made faster! Choose the right column for your needs with the HILIC stationary phase selection guide.

This document provides an explanation of HILIC and features various types of HILIC stationary phase columns. HILIC technology, which has complementary properties to both reverse phase (RP) and normal phase (NP) chromatography, is often used in studies analyzing hydrophilic analytes. Additionally, we offer a lineup of products including the "Ascentis Express OH5 HPLC column," "Ascentis Express ES-Cyano HPLC column," and others. We invite you to read through it. [Contents (excerpt)] ■ Ascentis Express U/HPLC columns ■ What is HILIC and reasons to choose it ■ Development of HILIC methods ■ Ascentis Express OH5 HPLC column *For more details, please refer to the PDF document or feel free to contact us.

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[Data] RP-Amide HPLC/UHPLC Column

Improvement of retention for carboxylic acids and phenolic compounds! Achieving low bleed suitable for LC-MS applications.

This document provides an explanation of "RP-Amide HPLC/UHPLC columns." It introduces the "characteristics of RP-Amide," the "differences in retention for neutral analytes," and the "increased retention for hydrogen bond donors." Additionally, it includes analyses of "ulcer medications using Ascentis RP-Amide" and "UHPLC measurements of sunscreen drugs using Ascentis Express RP-Amide, 2.7μm." We encourage you to read it. 【Contents】 ■Ascentis RP-Amide HPLC column ■Analysis of ulcer medications using Ascentis RP-Amide ■UHPLC measurements of sunscreen drugs using Ascentis Express RP-Amide, 2.7μm ■Data sheet on the care and use of Ascentis Express RP-Amide columns ■LC/MS workflow products ■Ascentis RP-Amide product list ■Fused-Core product list *For more details, please refer to the PDF document or feel free to contact us.

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Acclaim Surfactant Plus Column

For the analysis of consumables such as detergents, pharmaceuticals, food and beverages, and environmental samples! HPLC column.

The "Acclaim Surfactant Plus Column" is a state-of-the-art HPLC column with high efficiency and silica-based material. It allows for the simultaneous analysis of cationic surfactants, anionic surfactants, nonionic surfactants, and amphoteric surfactants. It can be used for the analysis of consumables such as detergents, pharmaceuticals, food and beverages, and environmental samples. 【Features】 ■ Selectivity suitable for the simultaneous analysis of cationic surfactants, anionic surfactants, nonionic surfactants, and amphoteric surfactants ■ Measurement of cationic surfactants ■ Separation of ethoxylated surfactants ■ Retention of highly hydrophilic compounds such as hydrotropes *Please feel free to contact us for more details.

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HPLC column "Acclaim Trinity P2 column"

An ideal solution for counterion analysis in pharmaceuticals.

The "Acclaim Trinity P2 Column" is a high-performance silica-based column. It is particularly suitable for HPLC analysis of counter ions in charged pharmaceuticals. The usage is simple, it boasts excellent robustness, and it allows for the analysis of both monovalent and multivalent ions using fast general-purpose methods. Using a general-purpose HPLC, it is possible to effectively analyze counter ions with just one column and one type of analytical method. 【Features】 ■ Effectively analyzes ions using HPLC ■ Enables screening of counter ions present in pharmaceuticals ■ Retains ions or ionic compounds without using ion-pair reagents ■ Simple to use ■ Provides reproducible packing *For more details, please refer to the PDF materials or feel free to contact us.

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Acclaim Mixed-Mode HPLC Column

A column that is expected to provide high separation.

Liquid chromatography aims to achieve good separation ability to obtain meaningful information through peak resolution. In mixed-mode chromatography, numerous parameters can be adjusted to optimize separation efficiency, allowing for effective control of separation performance. The Thermo Scientific Acclaim mixed-mode column features unique surface chemistry that facilitates easy adjustment of analyte elution, enabling maximum separation efficiency, which often leads to successful separation of compounds that cannot be addressed by other conventional high-performance liquid chromatography (HPLC) columns. The combination of ion exchange and reversed-phase, specifically HILIC chemistry, can extract the chemical properties of sample mixtures, allowing for complete separation of components in complex samples or high-sensitivity detection of trace samples. However, it is impossible to retain highly polar or charged analytes using only reversed-phase chromatography. Ion exchange (IEX) chromatography alone is insufficient for separating hydrophobic compounds. By using columns that combine different functionalities, a completely new toolkit is obtained for separating and evaluating samples.

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Fully porous HPLC column

You can easily change the method from a fully porous particle column to a surface porous particle column!

The product features various advantages of fully porous particle columns, such as high retention, load capacity, and solvent resistance. It can be expanded to suit your method, from UHPLC to preparative LC. Additionally, the InfinityLab Poroshell bonded phase is compatible with the traditional ZORBAX bonded phase, allowing for easy method changes from fully porous particle columns to superficially porous particle columns. 【How to choose the appropriate particle for your method (partial)】 ■1.8μm ZORBAX RRHD: Achieves the highest level of performance with UHPLC equipment - Maximum pressure: 1200 bar - Compatible systems: 1290 Infinity II LC or 1260 Infinity II Prime LC ■1.8 ZORBAX RRHT: Ultra-fast chromatography with a maximum of 600 bar - Maximum pressure: 600 bar - Compatible systems: 1260 Infinity II LC *For more details, please refer to the PDF document or feel free to contact us.

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ZORBAX Rx Reverse Phase HPLC Column

Rx-C18 is recommended for separation in low pH regions! It shows excellent stability and peak shape.

The "ZORBAX Rx Reverse Phase HPLC Column" is suitable for high-throughput analysis. It shows different selectivity compared to Eclipse XDB-C18 and StableBond SB-C18 in the low pH range, and StableBond is recommended for high-temperature applications. Additionally, Rx-C18 is manufactured using dimethyl octadecyl silane and demonstrates excellent stability up to pH 9 due to the lack of end-capping. 【Features】 ■ Shows different selectivity compared to Eclipse XDB-C18 and StableBond SB-C18 in the low pH range ■ Exhibits excellent stability and peak shape in low pH applications ■ Rx-C18 is manufactured using dimethyl octadecyl silane and demonstrates excellent stability up to pH 9 due to the lack of end-capping ■ Rx-C8 is the same product as SB-C8 *For more details, please refer to the PDF document or feel free to contact us.

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ZORBAX Extend-C18

Improvement of retention, separation ability, and peak shape in base compounds! Introducing ZORBAX reverse phase HPLC columns.

The "ZORBAX Extend-C18" utilizes a groundbreaking bidentate C18-C18 bonding technology, enabling the development of high-separation methods in high pH regions while being a silica-based column. The unique bidentate bonding and double-end capping enhance stability at high pH. It improves retention, separation capability, and peak shape for basic compounds. To extend column life, it is preferable to use triethylamine, ammonium hydroxide, or pyrrolidine as buffer solutions, while phosphate buffers are not recommended. 【Features】 - High separation efficiency and long lifespan in high pH regions (up to pH 11.5) - Improved stability at high pH due to unique bidentate bonding and double-end capping - Higher efficiency and superior peak shape compared to polymer-based columns - High sensitivity and separation for LC/MS analysis of peptides and proteins *For more details, please refer to the PDF document or feel free to contact us.

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HPLC column "Sunniest"

Developing a new combined phase! A column with an unprecedented end capping.

"Sunniest C18" uses a tri-functional reagent and features end-capping based on a unique new concept, making it the only one in the world. "Sunniest" significantly suppresses the influence of residual silanol groups, allowing for a wider range of conditions without tailing of basic compounds, and enabling the optimal setting of mobile phase pH and column temperature. 【Features】 ○ Almost no influence from silanol groups ○ Superior end-capping ○ The bonding reagent also has the effect of end-capping ○ RP-AQUA is prepared for stable separation with 100% aqueous mobile phase ○ Columns are available from an inner diameter of 2.0mm to 20mm for preparative use For more details, please contact us or download the catalog.

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ACE UltraCore UHPLC·HPLC Column

Solid core (core-shell) particles appear in the ACE column! Unique EBT technology achieves high stability across a wide pH range.

A new UltraCore column (HPLC/UHPLC column) has been added, featuring solid core (surface porous) particles from the UK ACE column group. Compared to conventional fully porous silica, it can be used at lower pressures, and due to the limited diffusion of analytes, it achieves high efficiency and sharp peak shapes. Additionally, it employs a unique encapsulation bonding technology (EBT) that delivers stable high performance across a wide pH range, dramatically increasing the ligand coverage on the silica surface and effectively eliminating the negative effects of unbound silanols. **Features** - Utilizes ultra-inert solid core particles (surface porous) - Monodisperse particle distribution combining low pressure and high efficiency - Expanded pH stability (1.5 to 11.0) - Compatible with LC/MS buffers - Employs unique encapsulation bonding technology (EBT)

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