ザルトリウス・ジャパン List of Products and Services

Cubis II is a balance that allows for full customization of hardware and software, enabling direct connection to LIMS and existing software. It provides reliable data with error-free operability. With updates to the software "Q App," it can flexibly respond to changing regulations. It allows for measurements compliant with pharmaceutical and food industry regulations, including data integrity, electronic signatures, and reporting functions in accordance with 21 CFR Part 11. 【Features】 ■ Built-in ionizer ■ Easy and seamless integration with existing software and LIMS ■ Diagnostic system to reduce human errors ■ Diverse communication options and user management settings ■ Flexibility to respond to future regulatory requirements through app updates ■ Auto-leveling ■ Fully customizable from various configuration patterns * For more details, please refer to the PDF materials or feel free to contact us.

• Weight related measuring instruments

We are currently offering a document titled "Live Cell Analysis Handbook" to researchers involved in live cell analysis, introducing our latest applications. While inheriting the digital upgrades from the previous edition, we have added a new section on embedded organoid assays and new data on phagocytosis assays. Additionally, we have included a chapter on label-free cell analysis. With a total of 342 pages, this comprehensive volume is filled with tips for conducting experiments more efficiently. [About this Handbook] Dedicated chapters for various applications using the "Incucyte Live Cell Assays" provide detailed explanations of live cell analysis. *You can immediately obtain the English version of the document via "PDF Download." Please feel free to contact us regarding the products introduced in the document.*

• Other analyses

In January 2020, the genomic sequence of COVID-19 was released, leading to many papers that brought breakthroughs related to the biology, vaccines, and therapeutic development of coronaviruses, featuring data from the Octet system for analyzing biomolecular interactions. The document "Advancing development of coronavirus vaccine and therapeutics," which can be downloaded from the catalog below, presents research papers that elucidate the binding kinetics and affinity, neutralization, cross-blocking, and potency of COVID-19 virus particles using the Octet system. ■ Rapidly screen and select optimal vaccine and therapeutic candidates ■ Ensure research progresses with the best candidates determined based on data *For more details, please refer to the PDF document or feel free to contact us. 【Contact Information】 Sartorius Japan K.K. BioAnalytics Tel: 03-6478-5200 E-mail: ForteBioJP@Sartorius.com

• Other physicochemical equipment

Octet Systems is an automated assay system that enables label-free, real-time measurement and analysis of interactions between biomolecules using Bio-Layer Interferometry (BLI) and Dip and Read assays. It eliminates the bottlenecks of traditional SPR methods, achieving high throughput, compatibility with diverse samples, and ease of use. The Octet system offers five models, allowing for the selection of the optimal system based on the number of samples, applications, and budget. 【Features】 ■ High-throughput assay method facilitates multi-sample assays and optimization of experimental conditions. ■ Capable of measuring crude samples such as cell lysates in their unrefined state. ■ Allows measurement of low-solubility samples using buffers containing high concentrations of DMSO solutions. ■ No complicated setup, shutdown procedures, or maintenance required. ■ The Dip and Read assay enables the recovery and reuse of samples after measurement. *For more details, please refer to the related catalog or feel free to contact us.

• Other physicochemical equipment
• Other inspection equipment and devices
• Testing Equipment and Devices

We are currently offering two documents introducing our latest applications to researchers involved in live cell analysis. You can view the 'Complete Guidebook for Live Cell Analysis (5th Edition)', which is packed with tips for conducting experiments more efficiently, and a 'White Paper' focused on virus research. [Main Contents] <White Paper "Accelerating Research on Viral Biology and Host Immunity with Advanced Cell Analysis Solutions"> ■ Host Infection and Virus Replication ■ Host Immune Response ■ Post-Infection Analysis and Preventive Immunity ■ Development of Therapeutics and Vaccines *You can immediately obtain them via "PDF Download." Please feel free to contact us regarding the products introduced in the documents.

• others

As a regulatory requirement, biopharmaceuticals must be QC tested using methods that are robust and appropriately qualified and validated under GMP conditions. The Octet system for analyzing biomolecular interactions is a reliable system that facilitates method development for in-process testing and lot release testing, and it can be easily transferred to QC. Due to its ease of use and high throughput characteristics, it can achieve up to 40 times the productivity of ELISA and up to 16 times that of SPR equipment in specific GMP applications. ■ The Octet CFR software and FB server functionality maintain secure and traceable electronic records. ■ The IQ/OQ/PQ package guarantees the required conditions and operations. ■ Validation support services for software and biosensors are provided. *For more details, please refer to the PDF materials or feel free to contact us.

• Other analyses
• Analytical Equipment and Devices

This is suitable for labs where high reliability and accuracy of results are required. It reduces errors in weighing tasks and streamlines operations. It features an easy-to-read large screen touch panel. The 'Cubis II' is a high-precision modular electronic balance that incorporates a large, easy-to-read touch panel and comes standard with an automatic leveling function (except for some models). It allows for weighing in compliance with regulations in the pharmaceutical and food sectors, including data integrity and electronic signature and reporting functions in accordance with 21 CFR Part 11. 【Campaign Overview】 We are currently running a campaign where you can try this product for free for two weeks. Free in-house seminars are also being held: 1. Basic knowledge of electronic balances and daily inspections 2. Data integrity compliance in electronic balances/Cubis II These can be conducted using a web system. Please make use of this for training and knowledge enhancement.

• Other electronic measuring instruments
• Other measurement, recording and measuring instruments

At Sartorius Japan, we are holding a launch commemorative campaign where all orders from July 1, 2021, to September 30, 2021, for the Arium device + sampling unit "Smart Station" will receive a 45% discount without exception. The "Arium Smart Station" features a compact design that easily fits into limited lab spaces. It allows for the collection of ultra-pure water drop by drop. During the campaign period, when you order the "Arium" pure and ultra-pure water production devices, including the "Arium Smart Station," we will offer special discounts on the Arium main unit, initial consumables, and accessories. 【Eligible Products】 ■ Ultra-pure water production device "Arium Pro Series" ■ Pure water production device "Arium Advance Series" ■ Pure and ultra-pure water production device "Arium Comfort Series" *For more details, please refer to the PDF materials or feel free to contact us.

• Pure water production equipment
• Other water supply and drainage facilities

The "IncuCyte S3" allows for simultaneous image analysis during cell culture, enabling time-lapse analysis of cells over periods ranging from hours to weeks. There is no need to remove cells for imaging each time, preventing damage to the cells. This results in rich data that ensures a clear understanding of important responses and interactions, visualizing all the changes in live cells that were not visible in endpoint assays. ★ This product is featured in the November 2019 issue of Nikkei Science as a product used in cancer immunotherapy research. You can view the relevant article through the PDF download. 【Reasons for Choosing This Product】 ■ Holds up to 6 microplates ■ Supports over 20 applications, including proliferation and apoptosis analysis (simultaneous execution of different applications is also possible) ■ You can leave after starting the assay. Remote operation via network connection is also possible ■ Selectable imaging modes for HD phase contrast and dual-color fluorescence (red and green) ■ Software automatically analyzes thousands of images ■ Over 2,000 published papers! *For more details, please refer to the catalog.

• Other analyses

This document concisely summarizes 10 key points to avoid contamination during pipetting. It includes detailed information on "regular cleaning of pipettes," "verification of chip purity and detection limits for contaminants," "use of tips with safe cone filters," and "utilization of pipette stands." To avoid contamination, it is essential to always be aware of the associated risks while working. Please use this information as a reminder. 【Contents (partial)】 ■ Regular cleaning of pipettes ■ Elimination of external contamination with highly airtight wrapping materials ■ Verification of chip purity and detection limits for contaminants ■ Attention to carryover ■ Avoiding splashes *For more details, please refer to the PDF document or feel free to contact us.

• Mixer/agitator
• others

Introducing the "Tacta Manual Pipette Multi-Pack," a smart solution for laboratories offered by Sartorius. The handle is ergonomically designed for easy grip, allowing pipetting and tip removal with minimal effort. We have a wide range of options available, including the "Tacta Pipette 3-Pack 10," "Tacta Pipette 3-Pack 20," and "Tacta Pipette 3-Pack Max." 【Features】 ■ High-quality standard tips ■ Excellent solutions for various applications ■ Diverse packaging options and purity options ■ Easy to clean with only three disassemblable parts ■ Fully autoclavable *For more details, please refer to the PDF document or feel free to contact us.

• pipette
• Other laboratory equipment and containers

The "Safetyspace Filter Chip" is ideally suited for use with Sartorius pipettes, maximizing accuracy and precision. The labels on the racks include the chip's capacity, product number, lot number, date, and purity level, allowing for high identification and traceability of the chips. The raw materials used for the chips, trays, and racks are 100% recyclable or can be incinerated for waste-to-energy purposes. 【Features】 ■ Capacity ranges from 10 to 5,000 μL ■ Fits perfectly with various pipettes, ensuring a tight seal ■ Color-coded chip trays make it easy to identify the appropriate Sartorius pipette for the chips ■ Single tray flip-top rack that can be easily opened and closed with one hand *For more details, please refer to the PDF document or feel free to contact us.

• pipette
• Other laboratory equipment and containers

This catalog is a comprehensive catalog featuring "high-quality pipette tips" handled by Sartorius Japan. It introduces "excellent quality and convenience," "high-quality tips that cater to various applications requiring pipetting," and "achieving high pipetting performance and accuracy," among other topics. Please take a moment to read it. 【Contents (excerpt)】 ■ Excellent quality and convenience ■ High-quality tips that cater to various applications requiring pipetting ■ A wide range of convenient packaging options ■ Order information ■ SafeCone filters to protect pipettes and samples *For more details, please refer to the PDF document or feel free to contact us.

• pipette
• Other laboratory equipment and containers

The "Entris II" is a low-cost laboratory electronic balance equipped with isoCAL, a LED touch panel, and 12 applications. It is made possible by the use of highly durable polybutylene terephthalate (PBT), stainless steel, and glass components that have high chemical resistance. To prevent secondary contamination, it features a design that can be easily cleaned with a wipe and parts that are easy to remove. 【Main Advantages】 ■ Easy cleaning that enhances operational efficiency and durability ■ isoCAL (internal calibration and adjustment) guarantees accurate weighing results ■ Hybrid screen that provides excellent readability and ease of use ■ Plug-and-play convenience ■ Data output for weighing applications to observe changes over time

• Other electronic measuring instruments
• Other measurement, recording and measuring instruments
• Other inspection equipment and devices

The "Zartclear" series is a one-step cell culture supernatant clarification filtration unit that eliminates the need for centrifugation. It contributes to saving your time and costs. Thanks to the filtration aid (diatomaceous earth), filtration proceeds without clogging. Furthermore, it not only allows for the filtration of cell culture supernatant while retaining the cells but also enables simultaneous clarification and sterilization filtration of the culture supernatant. Centrifugation before filtration is no longer necessary, saving both time and the cost of centrifuge tubes. 【Features】 ■ No pre-treatment required with centrifugation ■ Clarification and sterilization of cell culture supernatant can be performed in one step ■ Significantly reduces working time in the lab ■ Saves costs on centrifuge tubes ■ No clogging due to the filtration aid

• Filtration Equipment

This document introduces an interview with NBI Health Research Institute (Sapporo City), a biotech venture specialized in the development of monoclonal antibody drugs targeting G protein-coupled receptors (GPCRs). It includes efforts to produce antibodies against GPCRs, including G proteins. [Contents] ■ Controlling information transmission related to diseases ■ Capturing proteins exposed on the extracellular surface ■ High-speed flow cytometry as the key ■ The frontier spirit of Hokkaido blossoms *For more details, please refer to the PDF document or feel free to contact us.

• others

The "Entris II" is a low-cost basic electronic balance for laboratories, equipped with isoCAL, an LED touch panel, and 12 applications. It features a hybrid screen that ensures excellent readability and ease of use, along with the fully automatic calibration adjustment function isoCAL, guaranteeing accurate weighing results (I series only). Additionally, filter settings can be changed with a single touch to suit the installation environment. 【Features】 ■ Shortest class stabilization time, utilizing a new weighing sensor ■ GLP/GMP compliant printout and data output ■ Direct PC output without software (automatic output at any time interval is also possible) ■ A rich variety of 12 applications ■ Hybrid screen that ensures excellent readability and ease of use *For more details, please refer to the PDF materials or feel free to contact us.

• Weighing Machine
• Other weight measuring instruments
• Weight related measuring instruments

This document introduces various convenient modes (programs) available for use with the Picus electronic pipette. The "Picus electronic pipette" is compatible with 96 and 384 well plate assays. It can be utilized for PCR, enzyme immunoassays, cell culture, and more. Furthermore, it ensures faster, smarter operations with high reproducibility in fields such as cell biology and molecular biology. 【Contents】 ■ Cell culture: stirring and cell strains ■ How to avoid bubbles and foaming ■ Standard curves and calibration curves ■ PCR, cell assays, immunoassays, fluorescence assays, ELISA ■ Checking protein yield, sample or reagent volume ■ Sample collection *For more details, please refer to the PDF document or feel free to contact us.

• pipette
• Other inspection equipment and devices

The highly popular Safety Space series now includes a 5,000μL option. It is ideal for environments where sterile operations, such as cell culture, are conducted. • 5,000μL, sterilized, filter-equipped tips Single tray rack (50 tips per tray) • Uses a pure polyethylene filter tested for a bacterial filtration efficiency exceeding 99.99% • DNase, RNase, Endotoxin free* • Human DNA free* • Compatible with Sartorius 5,000μL pipettes <Contamination prevention with air gap filter tips> - Mainly the risk of contact between the sample and the filter - The risk of liquid contacting the filter when using the reverse pipetting method - Cross-contamination between aerosols and liquid contamination <Causes of contamination during pipetting> ■ Contamination from the sample to the pipette due to excessive aspiration of aerosols or liquids ■ Pipetting difficult samples (viscous or foaming liquids) causing the sample to enter the pipette ■ Use of non-sterile tips or tips without purity guarantees

• pipette

For customers looking for highly accurate electronic balances. Cubis II offers class-leading weighing performance and results through a design focused on error suppression and ease of use. Cost reduction: Its modular design allows for customization of only the necessary features. An integrated ionizer can also be selected. Achieving data integrity and compliance is easily attainable. **Product Features** - Seven types of shields to enhance efficiency - Twelve types of sample holders compatible with various flasks and samples - Error prevention with automatic leveling and built-in ionizer - Direct connection to LIMS and existing software - Applications packaged by theme *For more details about the product, please refer to the documentation. Feel free to contact us with any inquiries.*

• Other electronic measuring instruments
• Other measurement, recording and measuring instruments

This document is an application note that introduces guidelines and suitable pipetting methods to maximize the reproducibility of dispensing qPCR master mix. Experimental methods include pipetting techniques, qPCR setup, data analysis, and pre-rinsing of pipette tips before dispensing the master mix. 【Contents (excerpt)】 ■ Introduction ■ Experimental methods and pipetting techniques ■ qPCR setup ■ Data analysis ■ Results *For more details, please refer to the PDF document or feel free to contact us.

• pipette