パトコア Product Lineup

"ChemAIRS," which supports next-generation chemical R&D, is an AI-assisted reverse synthesis analysis and process optimization platform that integrates deep learning algorithms with over 80 million extensive chemical big data. It addresses challenges such as the "prolongation of synthetic route design" and "cost increases due to trial and error in experiments" in pharmaceutical and new material development through a data-driven approach. 【Dramatically Improving the Speed and Quality of Research and Development】 This system presents various synthetic routes for target compounds in just a few minutes (e.g., suggesting 15 routes in 11 minutes). With the condition examination feature utilizing AI optimization, it has achieved a 50% reduction in the number of experiments while attaining an initial yield that is 48% higher than conventional methods. AI complements the expertise of specialists, facilitating the discovery of innovative synthetic strategies. 【Advanced Predictive Functions to Prevent Experimental Risks in Advance】 Not limited to merely suggesting routes, it minimizes the risk of experimental failure through functional group compatibility assessments and impurity predictions boasting an accuracy of 83% to 90%. Additionally, by integrating with commercially available raw material databases and internal experimental records (ELN), it can identify the optimal "feasible routes" from both cost and feasibility perspectives.

"SARvision SM" is software that supports chemists in one of their important tasks: the examination of structure-activity relationships. With its unique Maximum Common Substructure (MCS) extraction engine, it can classify chemical structure data by scaffold, making SAR analysis easier. Scaffold-based data mining allows for evaluations that are closer to a chemist's intuition compared to descriptor-based clustering, proving effective in assessing screening data and formulating synthetic strategies during the Hit to Lead and lead optimization stages. 【NEW!】 A PROTAC analysis module has been released, allowing for routine and easy execution of SAR studies for bivalent ligands. For details, please visit the product page. 【Features】 ■ Automatically extracts common substructures from a group of structural formulas and presents a tree classified by scaffold. ■ Sorts scaffolds by physical properties or activity data, and allows dynamic filtering using sliders. ■ Rich graphic features (bar graphs, 2D scatter plots, 3D scatter plots). *For more information, please refer to the related links or feel free to contact us.

"AMEDEO" functions as an idea generator that allows non-experts to easily utilize advanced tools available in data science (AI and machine learning) to accelerate the lead optimization cycle. It learns about the data and builds and selects predictive models. It then clearly suggests which compounds should be created next. By simply answering a few easy questions regarding goals such as optimization items, it proposes candidates for biopharmaceuticals or small molecule drugs. 【Features】 ■ Idea generator to accelerate the lead optimization cycle ■ Learns about data and builds and selects predictive models ■ Clearly suggests which compounds should be created next ■ Just answer a few easy questions regarding goals such as optimization items ■ Proposes candidates for biopharmaceuticals or small molecule drugs *For more details, please refer to the PDF document or feel free to contact us.

●Unmatched data quality and scale GOSTAR is one of the world's largest databases of low molecular weight compounds, curated manually by top experts. It is organized, integrated, and updated through manual curation, allowing for immediate use in analysis and AI model development. By using GOSTAR, you can free yourself from the tasks of collecting and organizing data, enabling you to focus your valuable time on the most important research activities. GOSTAR is one of the largest low molecular SAR databases in the world, containing approximately 9 million low molecular weight compounds and nearly 30 million SAR data points. The database is built from 80,000 patents filtered from about 40 million and 200,000 research articles filtered from about 10 million, with data extracted through manual work by experts and standardized and structured based on specified rules. 【Features】 ■ A centralized data source for one of the largest low molecular SAR information collections in the world ■ Automatically adjusted for display based on the type of ligand, making it easy to read ■ Sortable by any data column and color-coded based on values *For more details, please refer to the PDF materials or feel free to contact us.*

■One of the largest and most reliable databases in the industry GOSTAR TPD is a specialized database that encompasses detailed structural information, activity data, and target protein information for over 51,000 target decomposition inducing agents (TPD) compounds. This product is certified with QMS (Quality Management System) and provides the latest and most reliable data through regular monthly updates. Researchers can quickly identify TPD compounds that meet their objectives using a flexible search function that combines multiple conditions of structure, target, and activity. It significantly reduces the effort of manually searching through vast literature and complex data. GOSTAR TPD dramatically improves the quality and speed of drug discovery research, strongly supporting the discovery of new therapeutic drugs. It provides an environment where complex TPD-related data can be understood simply and deeply, allowing researchers to focus on the core tasks of drug discovery. 【Features】 ■One of the largest domestic databases specializing in TPD structure, activity, and target ■High-quality data updated monthly, compatible with AI drug discovery ■Intuitive search UI maximizes research efficiency *For more details, please refer to the PDF materials or feel free to contact us.*

"Quick Request" is a testing request system that solves various issues related to test requests and realizes an efficient laboratory. It can manage the increasing number of compounds, diversifying and complicating tests, and various other tasks all in one system. Not only can you visually confirm the tests you are handling, but by consolidating communication channels between the requesting department and the testing department, it is possible to prevent communication and coordination errors in advance. 【Features】 ■ Flexible workflow ■ Access control tailored to operational forms ■ Visualization of testing status ■ Various options to enhance usability *For more details, please refer to the PDF materials or feel free to contact us.

Standard knowledge bases often cannot solve the specific challenges faced by customers. Excelra's senior experts and consultants understand the specific issues of customers and provide tailored solutions that meet their precise needs. Excelra has the expertise and experience to extract, structure, and organize unstructured data, transforming it into high-quality formats suitable for analysis, enabling data-driven decision-making based on information in drug discovery. When handling customer data, we adhere to the highest standards of data privacy and confidentiality, as proven by over a decade of partnerships with top-tier pharmaceutical companies and scientific publishers. We respond flexibly to short turnaround jobs without compromising on quality.