Cytiva List of Products and Services

The "Paul Laboratory Manifold" can be easily disassembled and assembled without the use of tools, making disinfection and sterilization straightforward. It is made of 316L stainless steel, providing chemical resistance, and all parts are sterilizable. It can be operated regardless of whether you are right-handed or left-handed, allowing for changes in installation location and suction direction. You can combine two three-way manifolds to use them as a six-way manifold. 【Features】 - Easy disassembly and assembly without tools, facilitating disinfection and sterilization - Operable regardless of right or left-handedness - Chemical resistance due to 316L stainless steel construction - Designed to prevent burping and backflow, ensuring a cleaner workspace - Various filter funnels can be used simply by swapping out the adapter - Two three-way manifolds can be combined to function as a six-way manifold *For more details, please refer to the PDF document or feel free to contact us.

• Microbiology

The "MicroFunnel ST Filter Funnel" can be used as an alternative to high-cost closed-system aseptic testing conducted with isolators and similar equipment. The 0.45 μm, 47 mm GN-6 Metricel membrane and low-adsorption Supor membrane are suitable for aseptic testing applications in the pharmaceutical industry. The design allows for easy separation of the container and plate with just a pinch, making membrane removal simple. It complies with the aseptic testing requirements of the United States Pharmacopeia, Japanese Pharmacopoeia, and European Pharmacopoeia. 【Features】 ■ Can be used as an alternative to high-cost closed-system aseptic testing conducted with isolators and similar equipment ■ Suitable for aseptic testing applications in the pharmaceutical industry ■ Supor membrane is ideal for antibiotic testing ■ Easy separation of the container and plate with just a pinch, making membrane removal simple ■ Complies with the aseptic testing requirements of the United States Pharmacopeia, Japanese Pharmacopoeia, and European Pharmacopoeia *For more details, please refer to the PDF document or feel free to contact us.

• Microbiology

The "MicroFunnel Plus Filter Funnel" is designed to use hot water samples up to 90°C. The sample container and filter funnel are integrated into a single structure. There is no need for the procedure of transferring the sample from the cup to the disposable funnel, eliminating the risk of contamination. 【Features】 ■ Designed to use hot water samples up to 90°C ■ Integrated structure of sample container and filter funnel ■ No need for the procedure of transferring the sample from the cup to the disposable funnel ■ Eliminates the risk of contamination ■ No risk of contamination from pollutants as filtration can be done without opening the funnel *For more details, please refer to the PDF document or feel free to contact us.

• Microbiology

The "MicroFunnel Filter Funnel" is a disposable, sterilized, individually packaged product that combines a membrane and funnel. The membrane can be easily removed by pinching the cylinder. Each lot is certified for microbial analysis, providing high assurance and reliable results. Additionally, the MicroFunnel equipped with a 0.45 µm membrane is useful for microbial testing and coliform count testing using the membrane filter method. The disposable design eliminates the need for cleaning or sterilization procedures. 【Features】 ■ Provides high assurance and reliable results ■ Sterilized and individually packaged, no need for autoclave sterilization ■ Proven track record for membrane filter method in environmental water coliform testing ■ Easy removal of the membrane ■ Prevents cross-contamination of samples ■ 100 mL funnel has markings in 10 mL increments ■ 300 mL funnel has markings in 50 mL increments *For more details, please refer to the PDF document or feel free to contact us.

• Microbiology

The "Sentino Magnetic Filter Funnel" can be operated with one hand thanks to its leak-proof magnetic seal. Available in 150, 300, and 500 mL sizes. The convenient 150 mL size easily fits into small autoclaves, while the 500 mL size is suitable for large sample filtration. The robust polyphenylsulfone plastic structure is splash-proof and provides a wide range of chemical compatibility. 【Features】 ■ Available in 150, 300, and 500 mL sizes ■ Operable with one hand due to the leak-proof magnetic seal ■ Provides a wide range of chemical compatibility ■ Easy to position ■ Graduated in 50 mL increments for accurate sample measurement *For more details, please refer to the PDF document or feel free to contact us.

• Microbiology

The "Sentino Filter Funnel" is a disposable device for microbial testing. By using the "Sentino Dispenser Pack" or "S Pack Membrane Device," the risk of cross-contamination is reduced compared to other reusable devices. Its compact design takes up little space even in a clean bench, creating an optimal experimental environment. 【Features】 ■ Sample solution does not accumulate in the notch of the scale ■ Available in sizes of 100 mL and 250 mL ■ Easy operation ■ Risk reduction ■ Compliance with regulations *For more details, please refer to the PDF document or feel free to contact us.

• Microbiology

The "Sentino Microbial Testing Pump" has a compact design, making it unobtrusive even when placed on a clean bench. Additionally, it is battery-operated, allowing for on-site filtration of water samples, making it suitable for fieldwork. With a 4-5 hour charge, it can filter the micro funnel (100 mL: water) over 60 times. It suppresses backflow seen in suction pump operations, preventing contamination during analysis. 【Features】 ■ Compact size ■ Portable ■ Disposable hose ■ Peristaltic pump *For more details, please refer to the PDF document or feel free to contact us.

• Other Laboratory Pumps

The "Sentino Filter Dispenser" is designed to allow for the sterile retrieval of membrane disks at the push of a button. The membranes can be easily set using tweezers on microbial testing devices that utilize MF technology. The footprint is compactly designed to take up minimal space on the testing table, and the membrane packs are small, making disposal easy. 【Features】 ■ Designed for sterile retrieval of membrane disks at the push of a button ■ Easily set using tweezers ■ Packaging seals are properly wrapped around the winding section ■ Compact design to minimize space on the testing table ■ Small membrane packs for easy disposal *For more details, please refer to the PDF materials or feel free to contact us.

• dispenser

The "Metricel Black Membrane Disc Filter" is a high-contrast membrane for the analysis of microorganisms and fine particles. The dark background provides ideal contrast for opaque colony counting in microbiological testing laboratories and for monitoring light-colored fine particles in process fluids within the microelectronics industry. It comes in sterilized individual packaging (S-pack) for stringent applications. 【Features】 ■ Provides ideal contrast ■ Unique grid pattern drawn with dots ■ Supports colony growth without promoting or inhibiting ■ Certified for use with the MF method ■ Sterilized individual packaging (S-pack) for stringent applications *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "Supor 200 Membrane Disc Filter" guarantees accurate analysis and does not inhibit colony growth due to its uniquely dot-patterned grid design. It allows for rapid and easy filtration due to its high flow characteristics and filtration capacity. It is certified for use with the Membrane Filter Method (MF method), and each box comes with a signed certificate for record-keeping. 【Features】 ■ Guarantees accurate analysis ■ Certified for use with MF method ■ Sterilized by gamma radiation ■ Reduced filtration time ■ Heat-resistant hydrophilic polyethersulfone membrane (maximum allowable use temperature 100°C) *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "GN-6 Metricel Membrane Disk Filter" achieves simple quantification without inhibiting or promoting the growth of bacterial colonies, thanks to its unique dot-drawn grid pattern. Cellulose mixed esters are commonly used materials for microbiological testing, providing high capture efficiency and recovery rates. It is suitable for microbiological testing using the MF method. 【Features】 ■ Cellulose mixed esters achieve high capture efficiency and recovery rates ■ Enables simple quantification without inhibiting or promoting the growth of bacterial colonies ■ Suitable for microbiological testing using the MF method ■ Each box includes a signed certificate for record-keeping ■ Various packaging methods to meet diverse needs *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "Filtration Sterilization and Clarification Disk Membrane Filter" can be widely used for various applications such as clarification filtration, pre-filtration, filtration sterilization, and virus removal. Scaling up is easy, reducing the need for re-qualification. The membrane's material composition is the same as that of large capsules and cartridge filters, so there is no need to change the material composition when transitioning from pilot scale to production scale. 【Features】 ■ The membrane's material composition is the same as that of large capsules and cartridge filters ■ Scaling up is easy, reducing the need for re-qualification ■ No need to change the material composition when transitioning from pilot scale to production scale *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "Polypropylene/Polyethylene Separator Depth Filter" has high chemical resistance and excellent wet strength. By using it in conjunction with submicron membrane filters, the total flow rate is improved due to the liquid channeling effect. It can be folded and handled similarly to laboratory filter paper. 【Features】 ■ High chemical resistance ■ Improved total flow rate due to the liquid channeling effect when used with submicron membrane filters ■ Excellent wet strength ■ Can be folded and handled similarly to laboratory filter paper *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "Supracap 50&100 Depth Filter Capsule" efficiently removes various sizes of cells, tissue fragments, and more, using three types of high-performance Seitz depth filter media. The "Seitz Bio 20 Media" is made of high-purity unmodified and modified cellulose membranes, free of inorganic materials. The "Seitz P Series Media" consists of cellulose fibers, filtration aids, and resins. Additionally, the "Seitz HP Series Media" is suitable for filtering solutions containing a high number of dead cells or solids, as well as solutions with particles of various sizes. 【Features of Seitz Bio 20 Media】 ■ High-purity unmodified and modified cellulose membranes, free of inorganic materials ■ Suitable for processing samples with ion sensitivity, such as protein solutions and dialysis fluids ■ Effective in protecting analytical applications such as columns through filtration *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "Polypure Capsule" is a high-density all-polypropylene pre-filter that extends the filtration lifespan of the final filter. Since all components are made of polypropylene, it achieves excellent chemical resistance and low extractables levels. The melt media and thermal bonding structure protect the purity and integrity of the filtrate. 【Features】 ■ All components are made of polypropylene ■ Achieves excellent chemical resistance and low extractables levels ■ Melt media and thermal bonding structure protect the purity and integrity of the filtrate ■ High dust-holding capacity improves filtration volume, especially when using high-viscosity solutions, extending the filtration lifespan of the final filter ■ Listed as compliant with materials that come into contact with food under 21CFR ■ High flow rate *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "Mini Profile Capsule" is a depth capsule designed for scale-up applications, utilizing high dust collection capacity depth media. It achieves a highly reliable absolute filtration accuracy. It features a unique design that combines the advantages of thick depth filters and conventional wide-area pleated filters. Additionally, it has a wide range of chemical resistance, is suitable for high-viscosity fluids, and offers two types of cartridge filters. 【Features】 ■ Uses high dust collection capacity depth media ■ Wide range of chemical resistance ■ Suitable for high-viscosity fluids ■ Achieves highly reliable absolute filtration accuracy ■ Provides two types of cartridge filters *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "AcroCap Pressure Filtration Device" provides rapid pressure filtration for medium-capacity aqueous solutions at the laboratory level. It prevents air locks with a complete hydrophobic air vent mechanism. The inlet can be connected to a 6.4 mm tube or various male luer slips, making it compatible with most pressure systems. 【Features】 ■ Prevents air locks with a complete hydrophobic air vent mechanism ■ Removes mycoplasma (0.1 μm pore size) ■ Compatible with most pressure systems ■ The inlet can be connected to a 6.4 mm tube or various male luer slips *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "VacuCap Filtration Sterilization Bottle Top Filter" is a revolutionary bottle top filter designed for rapid filtration sterilization of aqueous solutions ranging from 100 mL to 5 L and for the removal of mycoplasma. This filter minimizes plastic waste and is environmentally friendly, compatible with various collection containers, and helps reduce storage space and waste volume. 【Features】 - High flow rate achieved using Supor membrane - Removal of mycoplasma with a pore size of 0.1 μm - Filtration sterilization of culture media and supplements with a pore size of 0.2 µm - No need for additional injection into the upper liquid reservoir; direct suction from mixing containers is possible - Direct filtration into storage containers reduces contamination risk - Used as pre-filtration for exosome purification to remove microvesicles (0.1 µm, 0.2 µm) As an example of application, the 0.1 µm VacuCap is used for the clarification of supernatant from the culture of NIH3T3, a mouse embryonic fibroblast, as a preliminary step for concentrating and purifying exosomes. [1] Ji, H. et al., Electrophoresis. 29. 2660-2671

• Filtration Filter

The product features high flow rates, low protein adsorption, low preservative binding, broad chemical compatibility, and heat resistance. The "AcroPak 200 Fluorodyne II" capsules enable high-speed processing of clean batches. To minimize leachables, they are manufactured without adhesives and prevent vapor lock through the primary air vent. 【Features of AcroPak 20, 200, Fluorodyne II】 ■ Efficiently processes liquids up to 20 L ■ The "AcroPak 20 filter" is designed for small to medium-scale filtration ■ Prevents vapor lock through the primary air vent ■ Manufactured without adhesives to minimize leachables *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "AcroPak Capsule Filter - Supor EKV Membrane" extends product life due to the Mach V asymmetric membrane, while demonstrating maximum flow rate and throughput performance. The "AcroPak 20 - Supor EKV," designed for small to medium volume filtration, is disposable, reducing operational and related costs. It is suitable for filtering fluids containing low concentrations of proteins, preservatives, and other important components, making it ideal for filtering aqueous solutions, cell culture media, and serum. 【AcroPak 20 - Supor EKV Features】 ■ Design suitable for small to medium volume filtration ■ Product is disposable ■ System is scalable ■ Testing during scale-up can be significantly reduced ■ Testing costs are greatly reduced *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "AcroPak Capsule Filter - Supor Membrane" is suitable for solutions that require high flow rates, high filtration capacity, and low protein adsorption. The lineup includes "AcroPak 20 - Supor," "AcroPak 200 - Supor," and "AcroPak 500, 1000, 1500 - Supor." The built-in pre-filter extends the filtration lifespan when processing high-viscosity solutions or solutions containing a large number of fine particles (such as media containing serum). 【Lineup】 ■ AcroPak 20 - Supor ■ AcroPak 200 - Supor ■ AcroPak 500, 1000, 1500 - Supor *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "DMSO Safe Acrodisc Syringe Filter" features a polypropylene housing and nylon membrane that are resistant to solutions containing DMSO. It has excellent chemical compatibility with esters, bases, and alcohols. The effective filtration area is 2.8 cm², and the maximum operating temperature is 55°C. 【Features】 ■ Resistant to DMSO ■ Polypropylene housing and nylon membrane resistant to solutions ■ Excellent chemical compatibility with esters, bases, and alcohols *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "Acrodisc Syringe Filter - Versapor Membrane" can meet the needs for pre-filtration and clarification of various aqueous solution samples. It features a durable membrane that is flexible regardless of wet or dry conditions. It guarantees non-heat generation and biological safety. It is effective for pre-filtration of samples containing many fine particles, serum filtration, and dissolution tests, protecting equipment from particle accumulation. 【Features】 ■ Meets the needs for pre-filtration and clarification of various aqueous solution samples ■ Durable membrane with flexibility regardless of wet or dry conditions ■ Guarantees non-heat generation and biological safety *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "Acrodisc Syringe Filter - Mustang E Membrane" is a product equipped with a membrane that has a pore size of 0.2 μm, featuring hydrophobic interaction groups and anionic exchange groups. It removes endotoxins from water, buffers, neutral sugar solutions, and some biological solutions. It demonstrates high endotoxin binding capacity with minimal influence from the salt concentration and pH of the filtered solution. 【Features】 ■ Equipped with a membrane that has a pore size of 0.2 μm, featuring hydrophobic interaction groups and anionic exchange groups ■ Removes endotoxins from water, buffers, neutral sugar solutions, and some biological solutions ■ Less affected by the salt concentration and pH of the filtered solution ■ Shows high endotoxin binding capacity *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "Scale-Up Acrodisc Syringe Filter" is a laboratory-scale sterilization device made from the same materials as large-capacity capsule filters and cartridge filters. It includes options suitable for filtering solutions that require low protein adsorption characteristics, such as "Supor (PES)," which offers high flow rates and throughput performance, and "Fluorodyne II," which is suitable for applications that require PVDF membranes. It is ideal for small-volume sterilizing filtration, determining product compatibility and recovery, and conducting preliminary filtration performance tests. 【Product Lineup】 ■Supor ■Supor EKV ■Fluorodyne II ■Ultrapore ■Posidyne *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "Acrodisc Sterile Syringe Filter" features a Supor membrane made of PES, making it a versatile filter syringe for sterilization with high flow rates and low protein adsorption. Gamma-ray sterilization eliminates potential contamination from residual EOG. The Acrodisc PF and Sealam Acrodisc syringe filters are equipped with a unique pre-filter that increases the processing capacity for highly viscous solutions such as serum. Available in a wide range of sizes, it can accommodate sample volumes from 10 mL to 200 mL. 【Features】 ■ Excellent flow characteristics and high filtration capacity ■ Low protein adsorption minimizes sample loss ■ Gamma-ray sterilization eliminates potential contamination from residual EOG ■ A wide range of sizes (13 mm to 37 mm) available, accommodating sample volumes from 10 mL to 200 mL ■ The Acrodisc PF and Sealam Acrodisc syringe filters include a unique pre-filter that increases processing capacity for difficult-to-filter solutions ■ Mycoplasma removal using a pore size of 0.1 μm *For more details, please refer to the PDF document or feel free to contact us.

• Filtration Filter

The "Centramate Tangential Flow System for Laboratory Use" is suitable for processing capacities ranging from 1 to 125 liters in process development and small-scale production. Membrane cassette removal is easy without disassembling the system piping. By simply adding membrane cassettes [each cassette has a filtration area of 0.1 m²], the filtration area can be easily expanded to 0.5 m². Additionally, due to the same flow path length, linear scale-up to larger process systems is possible. There is a documented case of desalting antisense oligonucleotides obtained from solid-phase synthesis using the Centramate 1K membrane for nucleic acid synthesis applications. 【Features】 - Easily expand the filtration area to 0.5 m² by simply adding membrane cassettes - Linear scale-up to larger process systems is possible - Easy removal of membrane cassettes - Provided with SUS316L hardware - Various membranes are available for a wide range of applications Boos, J.A. et al., Nucleic Acids Research. 41 e145 (2013)

• Ultrafiltration

The "LV Centramate" is a product designed for the scale-up and scale-down of tangential flow filtration process development, small batch production of biopharmaceutical processes, scale-down testing, and the production of materials for safety and efficiency studies (Phase I clinical trials). With a low residual volume, it achieves high concentration factors from a small starting volume. Since it has the same flow path length as the Centramate cassette holder and Centrasette cassette holder, linear scale-up is possible. In a 2010 study, LV Centramate was used for the concentration of AAV viruses purified from cell culture supernatant [1]. 【Features】 ■ Linear scale-up is possible ■ Can also be used in conjunction with other lab TFF systems ■ Achieves high concentration factors from a small starting volume due to low residual volume ■ Easy connection with SUS316L polished luer lock ports, ensuring the same compatibility characteristics as the production scale Centrasette holder [1] Vandenberghe, et al., Human Gene Therapy. 21. 1251-1257 (2010).

• Ultrafiltration

The "Jumbosep Centrifugal Filtration Device" features a unique sealing mechanism that eliminates the need for O-rings, preventing leaks of concentrated liquid into the receiver. It is equipped with a dead stop mechanism to prevent drying and sticking upon completion of centrifugal filtration. The reservoir and receiver can be reused after autoclaving. 【Features】 ■ Rapid sample processing time ■ Over 90% recovery rate using low protein-binding Omega membranes ■ Color-coded for easy identification of a wide range of fraction molecular weights/pore sizes ■ Unique sealing mechanism design eliminates the need for O-rings, preventing leaks of concentrated liquid into the receiver ■ Built-in dead stop mechanism to prevent drying and sticking upon completion of centrifugal filtration ■ Reservoir and receiver can be reused after autoclaving *For more details, please refer to the PDF document or feel free to contact us.

• Ultrafiltration

The "MacroSep Advance Centrifugal Filtration Filter" is a 50 mL centrifuge tube type filter that quickly concentrates and recovers samples of up to 20 mL while minimizing loss. It features a low protein and DNA adsorption ultrafiltration membrane (Omega membrane) and housing. With a recovery rate of over 90%, it ensures the retention of concentrated liquid due to its dead-stop structure. It offers a wide range of fraction molecular weight sizes and can be easily identified by color coding. Recently, MacroSep 30K has been utilized in the first purification step of research on fluorescent gold nanoclusters using exosomes as templates [1]. **Features** - Low protein and DNA adsorption ultrafiltration membrane (Omega membrane) and housing - High recovery rate of over 90% - Rapid concentration of 20 mL samples to 0.5 mL - Retention of concentrated liquid due to dead-stop structure - Wide range of fraction molecular weight sizes - Easy identification through color coding *For more details, please refer to the PDF document or feel free to contact us.* [1] Lee, S. T. et al., Molecular Science 22. 4433-4441. (2021)

• Ultrafiltration

The "Microsep Advance Centrifugal Filtration Filter" is a 15 mL centrifuge tube type filter that can rapidly and accurately concentrate and recover samples up to 5.0 mL. It boasts a high recovery rate of over 90%. The large effective filtration area (3.3 cm²) allows for quick sample processing. The dead-stop structure ensures the retention of the concentrated liquid, and the color coding allows for easy identification. 【Features】 ■ Low protein and DNA adsorption ultrafiltration membrane (Omega membrane) and housing ■ High recovery rate of over 90% ■ Quick sample processing due to the large effective filtration area (3.3 cm²) ■ Dead-stop structure ensures retention of concentrated liquid ■ Rich variety of fractionation molecular weight sizes ■ Easy identification with color coding *For more details, please refer to the PDF materials or feel free to contact us.

• Ultrafiltration

Filtration of samples and mobile phases is a simple and efficient method necessary to extend the lifespan of consumable parts for HPLC, reduce wear and damage to the system, and maintain the integrity of the HPLC system. Acrodisc syringe filters offer the ideal membrane materials for your samples. The hydrophilic membranes made of nylon, PVDF, and Supor (PES) membranes are suitable for aqueous (water-based) samples. The hydrophobic PTFE membrane repels water and is inert to aggressive organic solvents, making it ideal for gases and organic solvents. The highly hydrophilic PTFE membrane is a versatile membrane that can be used for both aqueous and organic solvent applications.

• Filtration Filter

In October 2021, the Ministry of the Environment announced the revision of environmental standards related to water quality pollution. As a result of this revision, the standards concerning E. coli have been revised from total coliform counts to E. coli counts. The method for measuring E. coli counts is indicated as the so-called membrane filter (MF) method, which uses a membrane filter with a diameter of 47 mm and a pore size of 0.45 µm. In particular, when measuring E. coli counts, it is necessary to "store the sample in a dark place at 0-5°C (not frozen) if testing cannot be performed immediately after sampling, and it is desirable to test within 9 hours, and within 12 hours at the latest." Therefore, a micro funnel that can be used immediately after opening the bag without the need for prior sterilization is recommended. Cytiva's MicroFunnel integrates a funnel and filter, equipped with a membrane filter of diameter 47 mm and pore size 0.45 µm required for the MF method. The MicroFunnel can be easily detached by simply pinching the cylindrical part, making membrane recovery easy. It can also be connected to standard laboratory manifolds. Each unit is provided in individually packaged, gamma-sterilized form.

• Microbiology

Cytiva's individually packaged, sterilized membrane filters and filter funnels ensure microbial analysis in accordance with the membrane filter method (MF method). The GN-6 Metricel membrane, made of cellulose mixed esters, has established global standards for strict microbial control. Supor and Metricel black membranes further offer the advantages of low adsorption of drugs and proteins, as well as vibrant background color contrast that facilitates colony counting. These membranes provide customers with uniform and stable microbial culture. The MF method is efficiently executed with micro funnels that integrate the funnel and membrane. Equipped with membranes of 47 mm diameter and pore sizes of 0.45 µm or 0.2 µm, the funnel can be easily detached from the base by simply pinching it, allowing for easy handling of the membrane. It can be directly connected to standard laboratory manifolds and features graduated markings for easy measurement of sample volume. Each unit is provided in gamma-sterilized individual packaging, accompanied by a label for lot tracking for warranty purposes.

• Microbiology

Due to the revision of environmental standards related to soil contamination by the Ministry of the Environment, the filtration process for preparing the test solution for soil leaching tests has been amended as follows: "The entire supernatant after centrifugation shall be filtered using a membrane filter with a pore size of 0.45 µm and a diameter of 90 mm." We would appreciate it if you could consider Cytiva's Supor 450 membrane disc filter for this opportunity.

• Microbiology

**Protein Purification Using Sample Clarification and Filtration Sterilization Filter Plates** This is a 24-well type filter plate that allows for simultaneous clarification and filtration sterilization of multiple cell culture fluids and biological samples. The plate, which has a built-in pre-filter, can remove coarse particles and cell debris, while simultaneously performing filtration sterilization with a 0.2 µm main filter. It can be used for suction filtration with a dedicated suction manifold, and is also compatible with centrifugal filtration. Each well can hold up to 7 mL of solution, making it suitable for relatively large sample volumes, and it is ideal for the clarification process of multiple samples.

• Other cell research

Tangential flow filtration (TFF) is a filtration method that applies a constant pressure to the membrane side by flowing liquid samples parallel to the membrane surface, allowing solutes and small molecules to pass through the membrane. Compared to conventional direct flow filtration, TFF is less prone to filter clogging because it is continuously perfused parallel to the membrane surface, enabling efficient and large-capacity ultrafiltration. The Minimate EVO TFF system is suitable for large-scale protein and nucleic acid purification and is equipped with Omega membranes that have a wide range of molecular weight cut-offs (MWCO) from 1K to 1000K. It is also suitable for applications that require the purification of exosomes, which are extracellular nano-vesicles, from large volumes of cell culture media. It has been reported that TFF methods have a higher recovery rate of exosomes from cell culture media compared to ultracentrifugation [1], and there are also proven results with Minimate [2]. If you are considering large-volume sample ultrafiltration, please feel free to contact us. [1] Busatto S., et al., Cells, 7, 273-283 [2] Sung SE., et al., Int J Mol Sci, 22, 2889-2900

• Other filtration and separation equipment

The NAB NanoSep Spin Column is equipped with a two-layer silica-based quartz glass fiber membrane, enabling efficient binding of DNA and RNA, as well as rapid processing of samples. The two-layer membrane structure allows for a high maximum nucleic acid binding capacity, accommodating high concentrations of nucleic acid purification depending on the samples processed. The NAB NanoSep can be used as a column for nucleic acid purification, allowing for the extraction of plasmid DNA, genomic DNA, and total RNA from various cell and tissue samples. We can provide a high-quality, high-yield nucleic acid purification system compatible with the nucleic acid purification buffers you are currently using. 【Features】 • Rapid sample processing • Two-layer silica-based quartz glass fiber membrane enabling efficient binding of DNA and RNA • Low-adsorption polypropylene housing • Ultrasonic welding seal that does not cause bypass or sealing defects • Compatible with standard centrifuge rotors 【Material Composition】 Membrane: Two-layer binder-free, silica-based quartz glass fiber Housing: Polypropylene 【Effective Filtration Area】0.28 cm² 【Maximum Sample Capacity】500 μL

• Other purification and extraction

Acrodisc One is a syringe filter equipped with high wettability PTFE (wwPTFE). It is made from a material that has excellent chemical resistance, making it suitable for filtering a wide range of samples and analytical needs, from aqueous solutions to organic solvents. **Features** - Compatible with aqueous and organic solvent systems - Low adsorption, making it ideal for filtering a wide variety of reagents - Minimal leaching (HPLC guaranteed) - High particle retention capability, further extending column life **Material Composition** - Filter membrane: High wettability polytetrafluoroethylene (wwPTFE) - Housing: Polypropylene - GxF pre-filter: Binder-free borosilicate glass **Membrane Pore Size** - 0.2 and 0.45 μm - GxF pre-filter: 40 - 1 μm **Effective Filtration Area** - 13 mm: 1.0 cm² - 25 mm PSF: 3.9 cm² **Sample Capacity** - 13 mm: < 10 mL - 25 mm PSF: < 150 mL **Inlet/Outlet Connection Types** - 13 mm: Inlet: Female Luer Lock, Outlet: Mini Spike - 25 mm PSF: Inlet: Female Luer Lock, Outlet: Male Luer Slip

• Filtration Filter