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  3. アジレント・テクノロジー株式会社
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Testing, Analysis and Measurement
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アジレント・テクノロジー株式会社

EstablishmentNovember 1, 1999
number of employees17000
addressTokyo/Hachioji-shi/9-1 Takakuramachi
phone0120-477-111
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last updated:Mar 18, 2022
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アジレント・テクノロジー株式会社 List of Products and Services

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Multiple Affinity Removal Spin Cartridge - Human14

Remove 14 types of excess protein with a simple method.

The "Agilent Human 14 Multiple Affinity Removal Spin Cartridge" is an LC column designed for biopharmaceutical analysis that removes 14 types of proteins, including abundant albumin, from human plasma samples, making it easier to isolate and identify low-concentration proteins in human serum. By removing high-concentration proteins, the dynamic range of analysis can be effectively expanded. It can enhance the performance of LC/MS and electrophoresis analysis of serum samples. 【Features】 ■ Removes approximately 94% of total protein ■ Serum injection volume per analysis is 8-10μL ■ Unique high-speed single-injection protocol and optimized buffer ■ Capable of withstanding over 200 analyses or uses ■ Processes over 2,000μL of plasma/serum over its lifespan *For more details, please refer to the related links or feel free to contact us.

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Multiple Affinity Removal LC Column - Human 14

Removal of 14 types of excess protein using a simple method.

The "Agilent Human 14 Multiple Affinity Removal Column" is an LC column designed for biopharmaceutical analysis that removes 14 types of proteins, including abundant albumin, from human plasma samples, making it easier to separate and identify low-concentration proteins in human serum. By removing high-concentration proteins, it effectively expands the dynamic range of the analysis and enhances the performance of LC/MS and electrophoresis analysis of serum samples. It is compatible with most FPLC and HPLC pumps and instruments, including the Agilent 1200/1100 LC. 【Features】 ■ Removes approximately 94% of total protein ■ Available in three column sizes: - 4.6 x 50mm - 4.6 x 100mm - 10 x 100mm ■ Custom-made column sizes and spin cartridges are also available *For more details, please refer to the related links or feel free to contact us.

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Biopharmaceutical analysis LC column "PL-SAX for biomolecules"

Used in strong anion exchange chromatography with hydrophilicity! Rapidly perform column equilibration.

The "PL-SAX for Biomolecules" is an LC column used for the analysis of biopharmaceuticals in strong anion exchange chromatography with high hydrophilicity. By combining a robust macroporous styrene-divinylbenzene similar to PLRP-S with a polyethyleneimine coating that incorporates trimethylamine groups, it allows for the use of a wide range of pH and various solvents as the mobile phase necessary for the separation of biomacromolecules. Additionally, due to its high physical stability, it is suitable for high-speed separations using high flow rates and steep gradients. 【Features】 ■ Allows the use of a wide range of pH and various solvents as the mobile phase necessary for the separation of biomacromolecules ■ Suitable for high-speed separations using high flow rates and steep gradients ■ Rapid column equilibration ■ Column cleaning with organic solvents, strong acids/strong bases, and high salt concentration solutions is also possible *For more details, please refer to the related links or feel free to contact us.

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Column "GC FATWAX Ultra Inert"

Excellent inter-column inertness performance! Improvement of peak shapes for polar compounds that are difficult to analyze, such as free fatty acids.

The "GC FATWAX Ultranart" is a PEG-type GC column specialized for applications that separate fatty acid methyl esters, fatty acid ethyl esters, and fatty acids. To ensure reproducibility of FAME equivalent chain length values, proper identification of key FAMEs such as EPA, DPA, and DHA, and separation capability of major FAME pairs, tests using FAME mixtures have been conducted. Please feel free to consult us when you need assistance. 【Features】 ■ Column specialized for applications involving FAME, FAEE, and fatty acids ■ Individually tested with FAME mixtures and Ultranart Wax test mixtures ■ Excellent inertness between columns ■ Improved peak shape for polar compounds that are difficult to analyze, such as free fatty acids ■ High polarity, equivalent to USP G16 ■ The chemically bonded and cross-linked stationary phase can be cleaned with solvents and is compatible with water-soluble sample injections *For more details, please refer to the PDF document or feel free to contact us.

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Column "DB-WAX Ultra Inert"

Highly active and analytically challenging compounds, minimizing adsorption and decomposition! Achieving consistent inertness.

The "DB-WAX Ultra Inert" column provides symmetrical peak shapes and demonstrates better results for challenging polar compounds by using a highly inert polyethylene glycol. Individually tested with the Ultra Inert WAX test mixture based on QC specifications, it minimizes adsorption and decomposition for highly active, difficult-to-analyze compounds such as free fatty acids, alcohols, diols, and aldehydes, achieving consistent inertness. Additionally, it has the same selectivity as DB-WAX, allowing for easy column upgrades without the need to recreate existing compound libraries. 【Features】 ■ Improved peak shapes for challenging polar compounds ■ High inertness ■ Selectivity equivalent to DB-WAX: no need to revalidate methods ■ Equivalent to USP G16 ■ Excellent performance for acidic compounds including free fatty acids ■ Solvent-cleanable *For more details, please refer to the PDF document or feel free to contact us.

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Bioanalysis, conjugate reactions, peptide synthesis and purification.

Improvement of analysis through biomolecule synthesis and purification solutions! Introducing our product lineup.

We offer products related to "bioanalysis, conjugate reactions, peptide synthesis, and purification." Starting with a wide range of bioanalysis application tools for developers, we have items such as Protein A for detection. We also provide "resins, latex, and magnetic beads" to assist analysts in developing accurate and efficient workflows. 【Product Lineup】 ■ Protein analysis and conjugates ■ Affinity purified proteins ■ Resins, latex, and magnetic beads *For more details, please refer to the PDF document or feel free to contact us.

  • Chemicals
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Biopharma HPLC analysis

Ensure the reliable confirmation of important quality characteristics of biological products! Introducing our handled products.

We handle "BioPharma HPLC analysis" products. Ensuring the reliable confirmation of critical quality attributes of biological products. The Agilent AdvanceBio LC columns are designed and manufactured to provide reliable results when analyzing highly complex biopharmaceutical molecules and monitoring their purity, potency, and other important quality attributes. We offer a wide range of columns/consumables, including "protein removal," "aggregate and fragment analysis," and "amino acid and cell culture analysis." 【Product Lineup (partial)】 ■ Protein removal ■ Aggregate and fragment analysis ■ Amino acid and cell culture analysis ■ Antibody titer quantification ■ Charge variant analysis *For more details, please refer to the PDF document or feel free to contact us.

  • Analytical Equipment and Devices

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Syringe filter

Remove impurities to improve system performance and analysis quality! Introducing our products.

We handle "syringe filters." Our lineup includes "disposable syringes," "Captiva filter vials," "Captiva premium syringe filters," and "Captiva econo filters." Let's improve system performance and analysis quality by removing impurities before analysis. 【Lineup】 ■ Disposable Syringe ■ Captiva Filter Vial ■ Captiva Premium Syringe Filter ■ Captiva Econo Filter *For more details, please refer to the PDF materials or feel free to contact us.

  • Other laboratory equipment and containers

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Sample preprocessing product

We offer polymer-based SP suitable for extracting a wide range of compounds and SPE focused on specific applications.

We handle "sample pretreatment products." We offer a lineup of products such as "polymer-based SPE," which features a polymer surface covered with hydroxyl groups, a highly hydrophobic polymer interior, and a unique polymer structure suitable for extracting a wide range of compounds, as well as "silica-based SPE: reverse phase," which is used to retain and extract hydrophobic target substances in a polar matrix. Additionally, we also provide "silica-based SPE: normal phase" and "silica-based SPE: ion exchange." 【Partial lineup】 ■ Polymer-based SPE ■ Silica-based SPE: reverse phase ■ Silica-based SPE: normal phase ■ Silica-based SPE: ion exchange ■ Silica-based SPE: mixed mode *For more details, please refer to the PDF materials or feel free to contact us.

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Standard solution and reagents

We provide standard solutions and test samples! Introducing our product lineup.

We handle "standard solutions and reagents" at our company. Our lineup includes general-purpose chromatographic components such as "ULTRA standard substances," as well as "ICP-MS" and "ICP-OES" solutions, and "organic metal and oil" standard solutions for metals in hydrocarbon oils. Additionally, we also offer "standard solutions for atomic absorption" and "petroleum and biodiesel" standard solutions for metal and sulfur analysis in biodiesel. 【Partial Lineup】 ■ ULTRA standard substances ■ For ICP-MS ■ For ICP-OES ■ For atomic absorption (AA) ■ For petroleum and biodiesel ■ For organic metals and oil *For more details, please refer to the PDF materials or feel free to contact us.

  • Chemicals

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Syringe

For sample injection that requires precision! Introducing our products.

We handle "syringes" at our company. We offer a lineup that includes "auto-sampler syringes," "manual syringes," and "CTC auto-sampler syringes." For sample injections that require precision, please consider Agilent's wide range of manual syringes and auto-sampler syringes. 【Partial Lineup】 ■ Auto-sampler syringes ■ Manual syringes ■ CTC auto-sampler syringes ■ CTC smart auto-sampler syringes ■ Syringes for manual injection valves *For more details, please refer to the PDF document or feel free to contact us.

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Vial, cap, septum

Select the most suitable vials for your application! Introducing our product lineup.

We offer "Agilent Certified Vials, Caps, and Septa" products. Our lineup includes "A-Line Vials," "Crimp Tops," "Screw Tops," and "Snap Tops." Please select the vials that are suitable for your application to enhance the reliability of your analysis. Feel free to consult us when you need assistance. 【Partial Lineup】 ■A-Line Vials ■Crimp Tops ■Screw Tops ■Snap Tops ■Headspace Crimp Tops ■High-Performance Septa for Headspace Vials *For more details, please refer to the PDF document or feel free to contact us.

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Atomic Absorption (AA) Consumables

We provide consumables, standard substances, and solutions for atomic absorption! Introducing our columns/consumables.

We handle "consumables for atomic absorption (AA)" at our company. Our lineup includes "hollow cathode lamps" that provide cost reduction and excellent performance, as well as "flame atomic absorption systems" and "PSD samplers." Additionally, we manufacture and sell consumables for the PerkinElmer atomic absorption systems. 【Products We Handle (Partial)】 ■ Hollow Cathode Lamps ■ Flame Atomic Absorption Systems ■ PSD Samplers ■ SPS 3 Auto Samplers ■ SIPS 10/20 Sample Introduction Pump Systems *For more details, please refer to the PDF document or feel free to contact us.

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UV-VIS, FT-IR, fluorescent consumables

Let's regularly replace them to use the equipment comfortably! Here are the products we offer.

We handle "UV-VIS, FT-IR, and fluorescence consumables." Starting with the "8453 UV-Vis supplies," we offer a wide range of consumables for Agilent Cary series spectrophotometers, including "Cary UV-Vis supplies" and "cuvettes and flow cells." You can choose the cell material from four types based on the wavelength range of your measurements. 【Product Lineup】 ■ Parts and consumables for UV-Vis ・8453 UV-Vis supplies ・Cary UV-Vis supplies ・Cuvettes and flow cells ■ Parts and consumables for FT-IR ■ Parts and consumables for fluorescence spectrophotometers *For more details, please refer to the PDF document or feel free to contact us.

  • Spectroscopic Analysis Equipment
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Gas flow measurement and purification

Introducing our products, including flow measurement equipment and necessary piping!

We handle "gas flow measurement and purification" products. Our lineup includes "gas flow meters" used for measuring the flow of various gases and for OQ/PV of gas chromatography equipment, as well as "gas traps," which are important tools for removing impurities from various gases and optimizing the system performance of analytical instruments. Additionally, we also offer "leak detectors" and "piping, fittings, and tools." 【Products Available】 ■ Gas Flow Meters ■ Leak Detectors ■ Gas Traps ■ Piping, Fittings, and Tools *For more details, please refer to the PDF document or feel free to contact us.

  • Flow Meter
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Bio Online LC, capable of real-time bioprocess monitoring.

Supports PAT, process control, automation, and remote operation through bio-compatible functionality and real-time bioprocess monitoring.

Reliable Process Monitoring with Online LC The InfinityLab online LC solution allows for the automation of process monitoring. With real-time data availability, you can quickly grasp the status of the process and control it accurately. A key technology of this solution is the online sample manager, which easily associates analysis with the process. This module can automatically analyze samples either injected directly or taken from flow reactors, batch reactors, upstream bioreactors, or downstream purification devices.

  • Analytical Equipment and Devices
  • Separation device
  • Contract Analysis

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PFAS water quality testing

Compliance with Regulatory Challenges - A Comprehensive Workflow for PFAS Analysis

There is an increasing call for regulatory guidance and stringent requirements due to investigations showing that perfluoroalkyl and polyfluoroalkyl substances (PFAS) persist and accumulate in the body, raising health concerns. As a leader in the environmental analysis market for over 40 years, Agilent has deep insights and extensive experience in analytical methods for PFAS in water and environmental samples. We support a comprehensive workflow from extraction to screening, quantification, and reporting. We address our customers' needs regarding the challenges of PFAS analysis, from instrument setup to method development and optimization, execution of analyses, and obtaining results.

  • Analytical Equipment and Devices

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HAS/IgG Multiple Affinity Removal Spin Cartridge

A design that can remove a large amount of protein from human samples (such as plasma, serum, urine, or cerebrospinal fluid)!

We would like to introduce our product, the "HAS/IgG Multiple Affinity Removal Spin Cartridge." By removing a large amount of proteins, the dynamic range of analysis is effectively expanded, leading to improved sensitivity in subsequent sample LC/MS analysis and electrophoresis. Using the Multiple Affinity Removal System, approximately 69% of total proteins (albumin and IgG) are removed. 【Features】 ■ Serum injection volume per analysis: 50μL ■ High-speed single injection protocol and optimized buffer achieve favorable sample recovery rates ■ The optimized two-buffer system allows for highly reproducible reuse of the spin cartridge for over 200 analyses ■ Convenient spin cartridge reagent starter kit is also available *For more details, please refer to the related links or feel free to contact us.

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HAS/IgG Multiple Affinity Removal Column

Removal of albumin and IgG! This improves the sensitivity of subsequent sample LC/MS analysis and electrophoresis.

We would like to introduce the "HAS/IgG Multiple Affinity Removal Column" that we handle. The column format is "4.6 x 50mm," and custom-made column sizes and spin cartridges are also available. By using the multiple affinity removal system, approximately 69% of total proteins (albumin and IgG) can be removed. With an optimized two-buffer system, the column can be reused with very high reproducibility for over 200 injections, and it is provided with a convenient column reagent starter kit. 【Features】 ■ The serum injection volume per analysis is 100μL for a column with an inner diameter of 4.6mm. ■ The protocol and column are optimized for the analysis of human biological samples. ■ Compatible with most FPLC or HPLC pumps and equipment, including Agilent 1200 instruments. ■ Human serum albumin/IgG affinity removal spin cartridges are also available. ■ Up to 20,000μL of plasma/serum can be processed until the column's lifespan is reached (for a column with an inner diameter of 4.6mm). *For more details, please refer to the related links or feel free to contact us.

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HSA affinity removal spin cartridge

Compatible with standard benchtop microcentrifuges and lure-lock syringes!

We would like to introduce the "HSA Affinity Removal Spin Cartridge" that we handle. By removing albumin, the dynamic range of analysis is effectively expanded, and the sensitivity of subsequent sample LC/MS analysis and electrophoresis is improved. It is designed to remove a large amount of interfering proteins (albumin) from human samples (plasma, serum, urine, or cerebrospinal fluid, etc.). 【Features】 ■ The cartridge uses a multiple affinity removal system to remove approximately 50-55% of total proteins (albumin). ■ The serum injection volume per analysis is 65μL. ■ It can process over 13,000μL of plasma/serum until the lifespan of the spin cartridge. ■ Human albumin affinity removal LC columns are also available. *For more details, please refer to the related links or feel free to contact us.

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Affinity removal column for HSA use

High-speed single injection protocol and optimized buffer achieve favorable sample recovery rates!

We would like to introduce our "Affinity Removal Column for HSA." This column is designed to remove a large amount of interfering proteins (such as albumin) from human samples (plasma, serum, urine, or cerebrospinal fluid) using chromatography. By removing albumin, the dynamic range of the analysis is effectively expanded, which subsequently improves the sensitivity of sample LC/MS analysis and electrophoresis. 【Features】 - The injection volume of serum per analysis is 130μL for a column with an inner diameter of 4.6mm. - By using a multiple affinity removal system, approximately 50-55% of total proteins (albumin) can be removed. - With a column of 4.6 mm in diameter, up to 26,000μL of plasma/serum can be processed until the column's lifespan is reached. *For more details, please refer to the related links or feel free to contact us.

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mRP-C18 High Recovery Protein Column

Silica filled with porous C18 bonded ultra-pure 5μm particles that reduce or remove protein adsorption!

We would like to introduce our bio-pharmaceutical analysis LC column, the 'mRP-C18 High Recovery Protein Column'. This column and the desalting LC column can separate complex protein samples (e.g., immunodepleted serum or plasma proteins) into the number of fractions selected by the user, as well as perform desalting of the samples. It achieves significantly better recovery rates for protein samples compared to conventional RP HPLC columns. Please feel free to consult us if you have any requests. 【Features】 ■ Load up to a total of 380μg of protein ■ Available in two column sizes (0.5×100mm, 4.6×50mm) ■ Maximum operating pressure is 250bar (4000psi) ■ Compatible with water and all common organic solvents ■ Confirmed 95-99% protein sample recovery rate using immunodepleted serum with a multiple affinity removal system LC column *For more details, please refer to the related links or feel free to contact us.

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Biomonolith <Protein A, Protein G>

Used primarily for the quantification of IgG (calculation of fermentation potency)!

We would like to introduce our bio-pharmaceutical analysis LC column, 'Bio Monolith <Protein A, Protein G>'. It enables high-speed and accurate quantification of mAb antibody titers and allows for the purification of small amounts of mAb for further characterization. It can be used with HPLC and UHPLC systems, including Agilent 1100, 1200, and 1260 Bio Inert Quaternary LC. The Bio Monolith Protein G column is suitable for the purification of IgG molecules that do not bind to Bio Monolith Protein A. 【Features】 ■ Separation analysis of all IgG subclasses (human and mouse) ■ Protein G provides different selectivity for IgG molecules that do not bind to Protein A ■ Separation unaffected by flow rate ■ High-speed movement between mobile and stationary phases ■ Fixation of method parameters ■ Significant reduction in analysis time and buffer usage *For more details, please refer to the related links or feel free to contact us.

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Biomonolith

Designed for the separation of macromolecular biomolecules! Polymer-based monolith HPLC column.

We would like to introduce our bio-pharmaceutical analysis LC column, "Bio Monolith." It enables high-speed, high-resolution separation of antibodies (IgG, IgM), plasmid DNA, viruses, phages, and other macro biomolecules. Strong cation exchange phases, strong and weak anion exchange phases, and Protein A phases are available. It is compatible with HPLC and preparative LC systems such as the "1200 Infinity Series," as well as HPLC systems from other manufacturers. 【Features】 ■ Separation unaffected by flow rate ■ High-speed movement between the mobile phase and stationary phase ■ Ultra-fast separation ■ Accelerates method development and reduces costs by fixing method parameters *For more details, please refer to the related links or feel free to contact us.

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Capillary column/nano column

Compatible with various LC/MS interfaces! Available inner diameters of 0.5mm, 0.3mm, 0.1mm, and 0.075mm.

We would like to introduce our LC columns for bio-pharmaceutical analysis, 'Capillary Columns/Nano Columns.' You can choose from a wide variety of stationary phases, pore sizes, and dimensions. These columns are suitable for applications where the sample amount is extremely limited, as they enhance sensitivity by minimizing sample dilution within the column. 【Features】 ■ Extremely high sensitivity when the sample amount is very limited ■ Compatible with various LC/MS interfaces ■ Available inner diameters: 0.5mm, 0.3mm, 0.1mm, and 0.075mm ■ Stationary phases can accommodate a wide range of molecular weights, from small to large ■ Suitable for one-dimensional (1-D) and two-dimensional (2-D, proteomics) applications *For more details, please refer to the related links or feel free to contact us.

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VariTide RPC

Developing a polymer-based HPLC column to economically enhance throughput and analyze and purify synthetic peptides!

We would like to introduce our LC column for biopharmaceutical analysis, 'VariTide RPC.' To efficiently retain peptides composed of 5 to 60 amino acids, we adjust the particle size and pore size. It can be used at various pH ranges, allowing for the separation and purification of acidic, basic, hydrophilic, and hydrophobic peptides with this product. 【Features (Specifications)】 ■ Polymer: Macroporous spherical styrene-divinylbenzene ■ Particle size: 6μm ■ Pore diameter: 200Å ■ Functional groups: None ■ Column size: Inner diameter: 4.6mm to 21.2mm / Length: 25cm *For more details, please refer to the related links or feel free to contact us.

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PLRP-S allocation usage

The batch size of the filler is up to 600L! It is possible to fill a single batch of filler into multiple columns.

We would like to introduce our LC column for bio-pharmaceutical analysis, the 'PLRP-S for preparative use'. The PLRP-S packing material, made from robust polystyrene/divinylbenzene particles, is available in various pore sizes to enable the separation of a wide range of compounds, from low molecular weight to high molecular weight, including biopolymers. With excellent chemical stability (up to 1M NaOH), it allows for cleaning and regeneration, enabling long-term use of the column. 【Features】 ■ Capable of handling scales from drug discovery to several kg of cGMP manufacturing, reducing method development time. ■ Improved selectivity and extended column lifespan through chemical stability, optimization, cleaning, and regeneration of separations. ■ Reduced system downtime and validation costs by filling multiple columns in a single batch. *For more details, please refer to the related links or feel free to contact us.

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PLRP-S for bioanalysis

We offer a wide range of pore sizes and particle sizes! All have the same chemistry and fundamental adsorption characteristics.

We would like to introduce our LC column for the analysis of biopharmaceuticals, the 'PLRP-S for Bioanalysis'. Due to the hydrophobic nature of the polymer particles, there is no need for a bonded phase or alkyl bonding groups for separation in reverse phase systems. Therefore, residual silanol and heavy metal contaminants are absent, which does not affect the analysis results. We have suitable columns for separation and preparative purification for analytical purposes, and we can also provide process columns filled with bulk packing materials. 【Features】 ■ Thermally and chemically stable ■ Compliant with USPL21 ■ Pore sizes (100Å to 4000Å) suitable for separating complexes from low to high molecular weights and polynucleotides ■ Contains durable and robust polymer particles that provide highly reproducible results and a long column lifespan *For more details, please refer to the related links or feel free to contact us.

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PLRP-S for biomolecules

Chemically and physically stable and robust! LC column for biopharmaceutical analysis.

"PLRP-S for Biomolecules" is an HPLC column filled with macroporous styrene-divinylbenzene. It is a highly reproducible reverse-phase HPLC column, and there is no need for the attachment of alkyl chains (such as C18 or C8) to enhance hydrophobicity. Additionally, the surface of PLRP-S has no unnecessary activity, so there is no occurrence of separation inconsistency due to residual silanol or end-capping rates seen in silica-based fillers. 【Features (Specifications)】 ■ Polymer: Macroporous spherical styrene-divinylbenzene ■ Particle sizes: 3μm, 5μm, 8μm, 10μm, 30μm ■ Pore sizes: 100Å, 300Å, 1000Å, 4000Å ■ Functional groups: None ■ Usable organic solvent concentration: 1–100% (100% water is not allowed) *For more details, please refer to the related links or feel free to contact us.

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PL-SAX and PL-WAX for biomolecules

LC columns for biopharmaceutical analysis! Polymers are macro-porous spherical styrene-divinylbenzene.

We would like to introduce our products, "PL-SAX & PL-WAX for Biomolecules." "PL-SAX" is a column used in hydrophilic strong anion exchange chromatography. Additionally, due to its high physical stability, it can also be applied for high-speed separations using high flow rates and rapid gradients. Thanks to this excellent stability, the column can be equilibrated quickly, and it is also possible to clean the column with organic solvents, strong acids/strong bases, and high salt concentration solutions. 【Features (Specifications)】 ■ Polymer: Macroporous spherical styrene-divinylbenzene ■ Particle sizes: 5μm, 8μm, 10μm, 30μm ■ Pore sizes: 1000Å, 4000Å ■ Bonding functional groups: Trimethylamino groups ■ Concentration of organic solvents used: 0 to 100 *For more details, please refer to the related links or feel free to contact us.

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Fast Guard Column for Bioanalysis

Available for use with AdvanceBio Glycan Mapping Columns (2.7μm, surface porous, pressure resistant up to 600 bar)!

We would like to introduce the "Fast Guard Column for Bioanalysis" that we handle. The "Agilent Bio UHPLC Guard" is a high-performance guard column designed for Agilent's high-speed LC column family, using easy-to-install hardware that fits directly at the end of the column. By using the Fast Guard for UHPLC, you can extend the lifespan of the analytical column without compromising performance. 【Features】 - No special hardware required, just connect to the column - Comes in a package of three - Usable with AdvanceBio Peptide Mapping Columns (pressure tolerance 600 bar) - Usable with AdvanceBio Glycan Mapping Columns (1.8μm, pressure tolerance 1200 bar) - Extends the lifespan of high-speed LC analytical columns without degrading performance *For more details, please refer to the related links or feel free to contact us.

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ProSEC 300S

The filler has a nominal pore size of 300 Å! It is suitable for the analysis of a wide range of spherical proteins.

The "ProSEC 300S" is a silica-based column specifically designed for analyzing proteins using size exclusion chromatography. By removing acidic silanol and reducing interaction effects through a unique surface modification, it minimizes non-size exclusion effects across various types of proteins. With a particle size of 5μm, it offers high efficiency and improved separation capability, making it suitable for all protein analyses using salt buffer solutions. 【Features】 ■ Uses robust silica particles with no bleed during use ■ A single column with a wide linear separation range ■ Column dimensions compatible with multi-detector systems *For more details, please refer to the related links or feel free to contact us.

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ZORBAX Bio-SCX Series ii

LC and LC/MS columns! It is possible to achieve high retention and excellent peak shape.

The "ZORBAX Bio-SCX Series II" is a column designed for optimal 2D separation of peptides and proteins using LC/MS. The packing is based on 3.5μm ultra-high purity ZORBAX silica particles, combined with a polymer that is functionalized with sulfonic acid groups, taking into account environmental considerations. As a result, high retention and excellent peak shape can be achieved in the ion exchange procedures for 2D analysis of peptides and proteins. 【Features】 ■ Available in column configurations of 35mm length × 0.3mm inner diameter and 50mm length × 0.8mm inner diameter ■ pH range: 2.5 to 8.5 *For more details, please refer to the related links or feel free to contact us.

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ZORBAX Ion Exchange Column

Corresponding to organic solvent mobile phases! A lineup including ZORBAX SAX and 300SCX columns.

We would like to introduce the 'ZORBAX Ion Exchange Columns' for the analysis of biopharmaceuticals that we handle. The ZORBAX strong ion exchange columns come in two types: strong anion exchange (SAX) columns and strong cation exchange (300SCX) columns. Both columns are packed with 5μm silica particles, providing suitable analytical efficiency. 【Features】 ■ Stable from pH 2 to 7 ■ Achieves high efficiency and fast separation ■ Compatible with organic solvent mobile phases *For more details, please refer to the related links or feel free to contact us.

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Gel filtration column "ZORBAX GF-250/450"

A highly efficient, robust, and reproducible product for protein separation up to 3 mL/min!

The "ZORBAX GF-250/450" is a gel filtration column suitable for size separation of proteins and other biomolecules. When using the GF-250 and GF-450 columns in tandem, the separation range for spherical proteins is from 4,000 to 900,000. By using a hydrophilic diol bonded phase, it demonstrates a high protein recovery rate (typically >90%) and is compatible with a wide pH range of pH 3 to 8 due to its unique zirconia-modified silica. 【Features】 ■ Compatible with organic modifiers (<25%) and denaturants in the mobile phase ■ Capable of removing protein aggregates to accurately determine protein size ■ Common analytical applications include separation of monomers, dimers, and aggregates, desalting, estimation of protein molecular weight, and separation of modified proteins *For more details, please refer to the PDF document or feel free to contact us.

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Column "ZORBAX RRHD - Wide Pore"

Achieving excellent separation capability with 1.8μm particles in most defined separations!

The "ZORBAX RRHD-Wide Pore" is an LC column suitable for the analysis of biopharmaceuticals, providing highly reproducible separations of proteins and peptides. To efficiently separate proteins, peptides, or other macromolecules, the sample needs to be in close proximity to the stationary phase surface, which is why such a wide pore (300Å) column is necessary. Four different stationary phases (C18/C8/C3/Diphenyl) are available, allowing for the optimization of selectivity and recovery rates for proteins and polypeptides. 【Features】 ■ High-pressure (1200 bar) column for obtaining suitable results with the 1290 Infinity LC or other UHPLC systems ■ Usable with HILIC Plus ■ The selectivity remains the same for 3.5μm and 5μm ZORBAX columns with the same stationary phase, ensuring compatibility with various LCs *For more details, please refer to the PDF document or feel free to contact us.

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Column "ZORBAX RRHD 300 HILIC"

The HILIC function is specially designed for the separation of glycopeptide variants!

The "ZORBAX RRHD 300 HILIC" is a column for the analysis of glycopeptides, featuring a particle size of 1.8μm and a pore size of 300Å. It is designed to provide consistent and outstanding performance for the separation and characterization of peptides, proteins, antibodies, complexes, novel biomaterials, and biopharmaceuticals. The technology of AdvanceBio columns enhances accuracy and productivity, allowing for more information to be obtained in various characterization analyses. 【Features】 ■ Excellent peak shape for polar glycopeptides - These polar compounds typically cannot be separated using reverse phase columns. ■ High-speed analysis and stability up to 1200 bar - With a particle size of 1.8μm, it enables fast separation using UHPLC without compromising data accuracy. *For more details, please refer to the PDF document or feel free to contact us.

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Column "ZORBAX 300Extend-C18"

High robustness and separation of polypeptides and peptides over a wide range of pH from high pH to low pH (pH 2 to 11.5)!

The "ZORBAX 300Extend-C18" is a wide-bore HPLC column that efficiently separates peptides in the pH range of 2 to 11.5. Its unique bidentate bonding phase provides excellent longevity and reproducibility in both high and low pH regions. The retention characteristics and selectivity for peptides and polypeptides in the high pH region significantly change as these molecules become charged. 【Features】 ■ Shows different selectivity at high and low pH ■ Achieves excellent efficiency and good recovery rates for hydrophobic peptides at high pH ■ Suitable for LC/MS analysis using ammonium hydroxide mobile phase *For more details, please refer to the PDF document or feel free to contact us.

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Column "ZORBAX 300 StableBond"

In LC/MS analysis in low pH regions, formic acid and acetic acid can also be used as additives!

The "ZORBAX 300StableBond" is an ideal LC column for the analysis of biopharmaceuticals, designed to reproducibly separate proteins and peptides. To efficiently separate large molecules such as proteins and peptides, the sample must easily penetrate the stationary phase surface, which requires a wide pore (300Å) column. This product demonstrates excellent durability against the use of TFA-containing mobile phases in the low pH range typically used for protein and peptide separations. 【Features】 ■ Ability to optimize selectivity for peptides and proteins by utilizing four different stationary phases ■ Provides stability and longevity even when using TFA mobile phases at low pH ■ Excellent reproducibility ■ Offers capillary columns and nano columns suitable for LC/MS applications such as proteomics *For more details, please refer to the PDF document or feel free to contact us.

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"Poroshell 300" LC column for biopharmaceutical analysis

In addition to protein separation for analysis, it can also be used for LC/MS separation with ammonia-containing mobile phases!

The "Poroshell 300" is an ideal LC column for the analysis of biopharmaceuticals, designed for the rapid separation of proteins and peptides. This column, featuring unique particles, maintains sharp and efficient peak shapes even at high flow rates. With a unique particle structure that combines a porous silica surface thin phase and a hard silica core, it shortens the diffusion distance of proteins, enabling practical high-speed HPLC separations for peptides and proteins up to 500–1,000 kDa. 【Features】 ■ The Poroshell 300 column, bonded with StableBond phases (C18, C8, C3), exhibits excellent stability and sensitivity in TFA and formic acid mobile phases. ■ Usable at pH 2 to 11, it achieves unique separations and high selectivity. *For more details, please refer to the PDF document or feel free to contact us.

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Column "Agilent Bio Ion Exchange"

A wide lineup of 1.7, 3, 5, and 10μm particles in all sizes!

"Agilent Bio Ion Exchange" is an LC column for biopharmaceutical analysis filled with non-porous ion exchange polymer particles. It is designed to achieve high resolution, high recovery, and high-efficiency separation of peptides, oligonucleotides, and proteins. There are strong cation exchange (SCX), weak cation exchange (WCX), strong anion exchange (SAX), and weak anion exchange (WAX) phases. [Features] - Rigid non-porous poly(styrene-divinylbenzene) (PS/DVB) particles are grafted with a hydrophilic polymer layer to eliminate non-specific binding. - Uniformly filled ion exchange functional groups are chemically bonded to the hydrophilic layer (with multiple ion exchange groups per anchoring), increasing column capacity. - The particles, coating, and bonding are resistant to high pressure, promoting higher resolution and faster separation. *For more details, please refer to the PDF document or feel free to contact us.

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Agilent BioMAb LC Column for Biopharmaceutical Analysis

Particles, membranes, and bonds are resistant under high pressure, achieving higher resolution and faster separation!

The "Agilent BioMAb" is an LC column for biopharmaceutical analysis that uses a unique resin designed for high-resolution ion exchange separation of monoclonal antibodies. It is available in particle sizes of 1.7μm, 3μm, 5μm, and 10μm, with smaller particle size columns offering higher resolution. The packing material consists of rigid spherical cross-linked polystyrene-divinylbenzene (PS/DVB) non-porous beads. 【Features】 ■ Particles grafted with a hydrophilic polymer layer that virtually eliminate non-specific binding of antibody proteins. ■ A weak cation exchange (WCX) layer that is chemically bonded to a hydrophilic polymer coating, extremely uniform and densely packed. *For more details, please refer to the PDF document or feel free to contact us.

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Agilent BioSEC-5 LC Column for Biopharmaceutical Analysis

Achieving high reproducibility and long lifespan size-based separation for biomolecules!

The "Agilent BioSEC-5" is an LC column for biopharmaceutical analysis, filled with 5μm silica particles coated with a unique neutral hydrophilic layer to maximize column efficiency and stability. The specially designed packing increases pore volume, enhancing both peak capacity and resolution. To accommodate a wide range of size exclusion analyses, pore sizes of 100Å, 150Å, 300Å, 500Å, 1000Å, and 2000Å are available. 【Features】 ■ High recovery rates for a wide range of size-based biomolecule separations ■ Superior reproducibility and column lifespan compared to common products ■ Excellent stability under high pH, high salt, and low salt conditions ■ Usable with most aqueous buffers *For more details, please refer to the PDF document or feel free to contact us.

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Agilent BioSEC-3 LC column for biopharmaceutical analysis

Compatible with size exclusion analysis of most peptides and proteins!

The "Agilent BioSEC-3" is an LC column for biopharmaceutical analysis that realizes innovative technology in size exclusion chromatography (SEC). It is packed with 3μm silica particles coated with a unique hydrophilic layer. This thin polymer layer is chemically bonded to pure silica, which has sufficient mechanical strength under controlled conditions, resulting in very high separation efficiency in size exclusion. 【Features】 ■ Outstanding capacity, stability, and reproducibility for size-based separation of biomolecules ■ Sharper peaks, higher resolution, and excellent protein recovery rates ■ Achieves faster and higher separation than conventional SEC (size exclusion) columns ■ Compatible with most aqueous buffers ■ Excellent stability under both high salt and low salt conditions *For more details, please refer to the PDF document or feel free to contact us.

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Column "AdvanceBio Deionization RP Cartridge"

Time-saving through online sample desalting! Concentrate the sample before elution.

The "AdvanceBio Desalting RP Cartridge" is a column that can efficiently and rapidly remove salt ions online before MS detection. It can be used in combination with any LC system to desalinate collected fractions. Additionally, it can be used with the Agilent 1290 Infinity II 2D-LC system, performing desalting on the second dimension after separation on the first dimension. 【Features】 ■ Reduced MS downtime and maintenance ■ Improved data quality and reliability of results ■ Large pore size of 1000 Å suitable for biopharmaceuticals ■ Stability from pH 2 to 13 ■ Compatible with commonly used reverse phase mobile phases *For more details, please refer to the PDF document or feel free to contact us.

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