ナード研究所 List of Products and Services

The "Phos-tag technology" is a groundbreaking method for the separation, purification, and detection of phosphorylated substances using Phos-tag. Phos-tag is a functional molecule developed by the Laboratory of Pharmaceutical Molecular Function Science at Hiroshima University, which captures phosphate monoester anions (R-OPO32-) at neutral pH (physiological pH). Our company offers contract analysis using Phos-tag SDS-PAGE, providing strong support for research on protein phosphorylation. Additionally, we synthesize special Phos-tag compounds that have undergone chemical modifications such as various labeling, immobilization to single entities, and amino acid introduction. 【Features of Phos-tag SDS-PAGE】 ■ Enables analysis of substrate protein phosphorylation by kinases ■ Quantitatively visualizes phosphorylated and non-phosphorylated substrates ■ Analyzes the phosphorylation state of proteins within cells ■ Allows for Western blot analysis of target proteins ■ Bands can be excised from the gel after staining for mass spectrometry analysis *For more details, please refer to the related link page or feel free to contact us.

Thio-tag is a mononuclear zinc complex molecule developed at Hiroshima University Graduate School of Biomedical and Health Sciences, Department of Pharmaceutical Molecular Functional Chemistry, designed to capture thiol compounds. "Thio-tag Chloride" can protect SH-containing compounds such as cysteine thiol groups under physiological pH, room temperature, and air atmosphere, and can be used as a selective stabilizer for analysis. It can be easily dissociated under acidic conditions at pH 3 or through EDTA treatment. Additionally, we also offer "Thio-tag Tip," which allows for the separation and purification of thiol compounds at physiological pH. 【Product Lineup】 ■ Thiol Stabilization Buffer: Thio-tag Chloride ■ Thiol Affinity Chromatography: Thio-tag Tip *For more details, please refer to the related link page or feel free to contact us.

It is a benzylation reaction of hydroxyl groups under basic conditions. For substrates where the Williamson ether synthesis method cannot be applied, benzylation reactions under neutral or acidic conditions are effective. We offer a lineup of benzylating agents that can be used under neutral or acidic conditions. Additionally, we also accept contract manufacturing using such special benzylating agents, so please feel free to consult us. 【Lineup】 ■TriBOT ■TriBOT-PM ■DPT-BM *For more details, please refer to the related link page or feel free to contact us.

We propose a sublimation purification device that incorporates the experience and ideas of organic synthesis chemists. With precise temperature control, it is possible to produce high-purity organic compounds. Nard Laboratory assists in solving research and development challenges through contract synthesis, contract manufacturing, and contract research of chemical substances. We have a proven track record in a wide range of fields, including the research and development of pharmaceuticals, organic EL materials, organic semiconductors, and battery materials. 【Features】 ○ Achieves high yields through proprietary technology ○ Enables precise temperature control by optimizing heater structure ○ Maximizes prevention of thermal decomposition of substances by using high vacuum pumps For more details, please contact us or download the catalog.