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  3. ナード研究所
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ナード研究所

EstablishmentMarch 14, 1972
capital10000Ten thousand
number of employees153
addressHyogo/Amagasaki-shi/2-6-1 Nishichoshu-cho
phone06-6482-7010
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last updated:Apr 13, 2026
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合成・技術分野 合成・技術分野
特殊反応・特殊対応 特殊反応・特殊対応
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Development of moisturizing ingredients through glycan synthesis for cosmetics.

We support the development of moisturizing ingredients in cosmetics through glycan synthesis technology.

In the cosmetics industry, skin hydration is a crucial factor that influences customer satisfaction. The development of products for dry and sensitive skin requires high moisturizing effects and gentleness on the skin. Glycans are expected to be utilized as moisturizing ingredients due to their high biocompatibility and excellent water retention properties. Our company supports the development of moisturizing ingredients that meet customer demands using glycan synthesis technology. 【Application Scenarios】 - Development of highly moisturizing cosmetic ingredients - Development of cosmetics with minimal skin irritation - Exploration of new moisturizing ingredients 【Effects of Implementation】 - Realization of high value-added cosmetic development - Improvement of customer satisfaction - Differentiation from competitors

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Glycan synthesis technology for drug discovery

Supporting drug discovery research from linear glycan chains to complex branched structures.

In the drug discovery industry, it is important to understand the interactions with target molecules and design effective drugs in the development of new medications. Glycans play a crucial role in cell recognition and signal transduction, and they are also gaining attention as drug discovery targets. Glycan synthesis technology is essential to accelerate research on these targets. Our company conducts glycan and glycan derivative synthesis at various scales, from a few milligrams for research purposes to process development aimed at future commercialization. 【Application Scenarios】 - Research on glycans as drug discovery targets - Development of novel drugs based on glycans - Enhancement of drug functionality through glycan modification 【Effects of Implementation】 - Acceleration of drug discovery research - Expansion of possibilities for new drug development - Deepening understanding of target molecules

  • others

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Glycan Synthesis Technology for Regenerative Medicine

Support for cell scaffold formation through glycan modification of scaffold materials.

In the field of regenerative medicine, the quality of materials that serve as scaffolds for cells greatly influences therapeutic effects. In particular, the biocompatibility of scaffold materials is crucial for promoting cell adhesion and proliferation. Glycans play an important role in cell recognition and signal transduction, and by introducing glycans into scaffold materials, it may be possible to enhance scaffold formation by cells and improve the efficiency of regenerative medicine. Our glycan synthesis technology supports problem-solving in regenerative medicine through glycan modification of scaffold materials. 【Application Scenarios】 - Glycan modification of scaffold materials - Cell culture - Tissue regeneration 【Effects of Implementation】 - Improved cell adhesion - Promotion of cell proliferation - Increased efficiency of tissue regeneration

  • others

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Synthesis of inorganic compounds for batteries

Developing electrode materials through the preparation of ceramic precursors using the Zolger method!

The battery industry is seeking the development of high-performance electrode materials. In particular, improving energy density and durability are important challenges. Appropriate material synthesis is a crucial factor that influences battery performance. Our inorganic compound synthesis services support the synthesis of electrode materials that meet our customers' needs. 【Application Scenarios】 - Electrode materials for lithium-ion batteries - Electrode materials for all-solid-state batteries - Electrode materials for next-generation batteries 【Benefits of Implementation】 - Improved performance of electrode materials - Extended battery lifespan - Increased energy density

  • Processing Contract

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Synthesis of inorganic compounds for environmental catalysts

Support for catalyst development through the preparation of ceramic precursors using the Zolger method.

In the field of environmental catalyst development, there is a demand for both improved reaction efficiency and durability. In particular, high-performance catalysts are essential for exhaust gas purification and improving energy conversion efficiency. The synthesis technology of inorganic compounds precisely controls the composition and structure of catalysts to address these challenges. Our company supports customers' catalyst development through the preparation of ceramic precursors using the sol-gel method and various firing treatments in different atmospheres. 【Application Scenarios】 - Exhaust gas purification catalysts - Fuel cell catalysts - Photocatalysts 【Benefits of Implementation】 - Improved catalyst performance - Enhanced durability - Reduced development time

  • Processing Contract

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Synthesis of inorganic compounds for automobiles

Developing exhaust gas purification catalysts using the Zolger method for ceramic precursor preparation!

In the automotive industry, the development of high-performance exhaust gas purification catalysts is required to comply with exhaust gas regulations. In particular, improving the durability of catalysts and achieving more efficient exhaust gas purification performance are crucial. Inadequate catalysts can make it difficult to meet exhaust gas regulations and may increase environmental impact. Our inorganic compound synthesis services support the development of high-performance exhaust gas purification catalysts through processes such as the preparation of ceramic precursors using the sol-gel method and firing treatments in various atmospheres. 【Application Scenarios】 - Development of exhaust gas purification catalysts - Manufacturing of automotive parts 【Benefits of Implementation】 - Improved exhaust gas purification performance - Compliance with environmental regulations

  • Processing Contract

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Low Metalization Service for Chemistry

Low metalization service for resist materials and organic electronics materials.

In the chemical industry, improving catalytic activity requires high purity of materials, particularly the reduction of metal impurities. Metal impurities can inhibit catalytic reactions and potentially decrease reaction efficiency and selectivity. The low metal service offered by Nard Research Institute utilizes various purification techniques, including sublimation purification, to achieve a reduction of metal components (from ppm to ppb), thereby contributing to the enhancement of catalytic activity. 【Application Scenarios】 - Purification of catalytic materials - Improvement of reaction efficiency - Enhancement of selectivity 【Effects of Implementation】 - Improvement of catalyst performance - Optimization of reaction processes - Enhancement of product quality

  • others
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  • Other metal materials

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Low Metalization Service for Solar Cells

Providing low-metalization services that contribute to improving solar cell efficiency!

In the solar cell industry, there is a demand for high purity of materials to achieve higher performance and longer lifespan. In particular, metal impurities are one of the factors that degrade the performance of solar cells. Our low metalization service reduces metal components in resist materials and organic electronics materials, contributing to the improvement of solar cell efficiency. 【Application Scenarios】 - Removal of metal impurities from materials in the solar cell manufacturing process - Improvement of material quality in solar cell performance evaluation 【Effects of Implementation】 - Improvement of solar cell conversion efficiency - Extension of solar cell lifespan - Enhancement of product quality

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  • Other contract services
  • Other metal materials

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Low Metalization Service for Displays

Reduce metal impurities in resist materials and organic EL materials, contributing to high image quality!

In the display industry, reducing the purity of materials, especially metal impurities, is crucial for achieving high image quality. Metal impurities can cause uneven displays and reduced brightness, potentially compromising product quality. Our low-metal service reduces metal components in resist materials and organic EL materials to ppm to ppb levels, contributing to high image quality in displays. 【Application Scenes】 - Organic EL Displays - LCD Displays - Other High-Quality Displays 【Benefits of Implementation】 - Improved display quality - Enhanced product reliability - Improved yield

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  • Other contract services
  • Other metal materials

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Low Metalization Service for Semiconductors

Providing low metalization services for resist materials and organic electronics materials.

In the semiconductor industry, achieving high purity of materials is essential to maximize product performance. Particularly in resist materials and organic electronics materials, the presence of metal impurities can lead to degradation of device performance and reduced yield. Our low metal content service addresses these challenges with purification technology based on years of experience. 【Application Scenarios】 - High purity of resist materials - Removal of metal impurities from organic EL materials - Cleaning of materials in the semiconductor manufacturing process 【Benefits of Implementation】 - Improved device performance - Enhanced yield - Increased product reliability

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  • Other contract services
  • Other metal materials

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Pesticide Compound Library Synthesis Service

Providing a small number of samples for multiple specimens! Accelerating herbicide development.

In the development of new formulations in the pesticide industry, comprehensive and efficient screening of diverse compounds is key to success. The expansion of resistance to existing pesticides and the increasing demands for safety and environmental impact make the continuous creation of new modes of action and improved compounds essential. However, the synthesis of candidate compounds requires significant time and cost, necessitating the establishment of a more efficient research and development process. Our compound library synthesis service strongly supports the design, development, and optimization of candidate structures in pesticide (insecticides, fungicides, herbicides, etc.) research and development. 【Application Scenarios】 - Exploration of new pesticide candidate compounds (insecticides, fungicides, herbicides, etc.) - Structural development and improvement considerations for existing pesticide active ingredients - Design and evaluation of compound series with new modes of action - Library synthesis for SAR studies around candidate compounds 【Benefits of Implementation】 - Synthesis of diverse structural libraries with multiple samples in a short period - Reduction of research and development costs and man-hours by complementing in-house synthesis resources - Stable supply of high-quality compounds based on reproducible synthesis processes - Consistent synthesis support from the exploration stage to the optimization stage

  • Other contract services

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Compound library synthesis service for drug discovery lead exploration.

Providing a small number of samples for multiple specimens! Accelerating drug discovery research.

In the drug discovery industry, there is a demand for the rapid provision of diverse compound libraries for lead exploration. To enhance the efficiency of candidate compound exploration, it is crucial to efficiently synthesize compounds with diverse structures and provide them for screening. Our compound library synthesis service offers a small number of samples derived from basic scaffolds in a multi-sample format, strongly supporting lead exploration in drug discovery research. Keywords: Combinatorial Chemistry, Compound Library, Multi-Sample Synthesis, Parallel Synthesis 【Usage Scenarios】 - Exploration of lead compounds - SAR (Structure-Activity Relationship) studies - Optimization of hit compounds 【Benefits of Implementation】 - Improved screening efficiency through the rapid provision of diverse compounds - Reduction of research duration - Discovery of optimal compounds for drug targets - Acquisition of reliable research data through the provision of high-quality compounds

  • Other contract services

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Manufacturing support services

Leave process development to us! We will achieve industrialization safely and swiftly.

Nerd Research Institute's contract manufacturing collaborates with its 100% subsidiary, Nerd Chemicals Co., Ltd., to meet a wide range of requests from initial prototype manufacturing in the early stages of development to product manufacturing. Nerd Chemicals prides itself on a high-quality assurance system and flexible responses, adapting to the provision of products in various fields. Among its strengths, it excels in process development for industrialization, with a research and development team specializing in process examination that aims to establish safe and reliable manufacturing methods that meet the required specifications of customers. [Nerd Chemicals' Features] ■ Skilled in small-batch, multi-product manufacturing ■ High technical level of each employee ■ Quality assurance system that meets expectations (GMP standards, ISO 9001) *For more details, please download the PDF or feel free to contact us.

  • Contract manufacturing

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Flow synthesis service

Condition examination - supporting up to kilogram production! Introducing our services.

We would like to introduce our "Flow Synthesis Service." With years of experience, we provide support for flow synthesis. We can quickly facilitate the transition from batch synthesis to flow synthesis. Please feel free to contact us when you need assistance. 【Features of Our Contract Synthesis】 ■ No synthesis data? No problem! We can propose synthesis methods for new compounds. ■ Our researchers engage in direct dialogue, smoothly reflecting your requests in planning and results. ■ We work together with customers to think of solutions to research challenges. *For more details, please download the PDF or feel free to contact us.

  • Processing Contract

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Synthesis of inorganic compounds

Conducting the preparation of ceramic precursors using the Zolger method and various firing treatments in different atmospheres!

We would like to introduce our "Synthesis of Inorganic Compounds." We conduct the synthesis of nanoparticle-supported catalysts, raw material mixing using a planetary ball mill, and investigations into the sublimation purification of inorganic compounds. Please feel free to contact us when you need our services. 【Features of Our Contract Synthesis】 ■ No synthesis data? No problem; we can propose synthesis methods for new compounds. ■ Researchers engage in direct dialogue to smoothly reflect your requests in planning and results. ■ We work together with customers to think of solutions to research challenges. *For more details, please download the PDF or feel free to contact us.

  • Processing Contract

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Synthesis of polymer processing materials

Conducting a total of four types of synthesis: radical polymerization, ionic polymerization, step-growth polymerization, and modification reactions!

We would like to introduce our company's "Synthesis of Polymer Processing Materials." We carry out the synthesis of terminal functionalized polymers using chain transfer agents, the synthesis of polybutadiene through anionic polymerization, and the introduction of functional group terminals using chain transfer agents. Please feel free to contact us when you need our services. 【Features of Our Contract Synthesis】 ■ No need for synthesis data; we can propose synthesis methods even for new compounds. ■ Researchers engage in direct dialogue to smoothly reflect your requests in planning and results. ■ We work together with customers to think of solutions for research challenges. *For more details, please download the PDF or feel free to contact us.

  • Processing Contract

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Low metalization service for organic materials

We will streamline research and development with low metalization process development services!

Nerd Research Institute offers low metalization services for customers who wish to explore low metalization options. When it comes to low metalization of organic materials, it is necessary to consider synthetic methods using metal-free containers and equipment, purification methods for the removal of metal elements, and analytical methods regarding the stability and reproducibility of analyses. Our company streamlines research and development with our low metalization process development services. 【Features of Our Contract Synthesis】 ■ No need for synthesis data; we can propose synthesis methods even for new compounds. ■ Researchers engage in direct dialogue to smoothly reflect your requests in planning and results. ■ We work together with customers to think of solutions for research challenges. *For more details, please download the PDF or feel free to contact us.

  • Processing Contract

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Synthesis of organic compounds

Achieving high purity of materials using various purification techniques such as recrystallization, distillation, and chromatography!

We would like to introduce our "Synthesis of Organic Compounds." We deliver over 1,000 compounds annually and have a proven track record in most organic reactions. We can propose syntheses even for compounds that have not been reported in literature or patents. Please feel free to contact us when you need assistance. 【Refining Techniques】 ■ Recrystallization ■ Distillation ■ Chromatography ■ Sublimation purification ■ Clean environment *For more details, please download the PDF or feel free to contact us.

  • Processing Contract

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Nerd Research Institute Co., Ltd. Company Information

We provide a wide range of support in organic chemistry (low molecular and high molecular), inorganic chemistry, material formulation, and more.

Nard Laboratory Co., Ltd. is a contract research and manufacturing company specializing in research and development with many years of proven experience. We solve the challenges faced by researchers dealing with compounds, such as the inability to obtain necessary reagents, lack of knowledge about synthesis methods, the need for larger quantities of higher purity reagents, and the desire to consult with chemistry experts. Our company has a Life Sciences Research Division, a Materials Science Research Division, and a Corporate Research Division. [Business Activities] ■ Support for drug discovery research and synthesis ■ Custom synthesis of functional molecules *For more details, please download the PDF or feel free to contact us.

  • Contract manufacturing

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Thio-tag Technology

We also have bulk products available! Introducing mononuclear zinc complex molecules that capture thiol compounds.

Thio-tag is a mononuclear zinc complex molecule developed at Hiroshima University Graduate School of Biomedical and Health Sciences, Department of Pharmaceutical Molecular Functional Chemistry, designed to capture thiol compounds. "Thio-tag Chloride" can protect SH-containing compounds such as cysteine thiol groups under physiological pH, room temperature, and air atmosphere, and can be used as a selective stabilizer for analysis. It can be easily dissociated under acidic conditions at pH 3 or through EDTA treatment. Additionally, we also offer "Thio-tag Tip," which allows for the separation and purification of thiol compounds at physiological pH. 【Product Lineup】 ■ Thiol Stabilization Buffer: Thio-tag Chloride ■ Thiol Affinity Chromatography: Thio-tag Tip *For more details, please refer to the related link page or feel free to contact us.

  • Other polymer materials

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Triazine-type hydroxyl protecting agent

We offer a lineup of benzylating agents that can be used under neutral or acidic conditions!

It is a benzylation reaction of hydroxyl groups under basic conditions. For substrates where the Williamson ether synthesis method cannot be applied, benzylation reactions under neutral or acidic conditions are effective. We offer a lineup of benzylating agents that can be used under neutral or acidic conditions. Additionally, we also accept contract manufacturing using such special benzylating agents, so please feel free to consult us. 【Lineup】 ■TriBOT ■TriBOT-PM ■DPT-BM *For more details, please refer to the related link page or feel free to contact us.

  • Other contract services
  • Contract manufacturing
  • Chemicals

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PET business

Short delivery time! Available for sale with a purity of over 98%, starting from a minimum quantity of 10mg.

Nard Institute was founded in 1972 starting from contract research business and began custom synthesis of PET reagents in 1995. For PET reagents, we have a wealth of synthesis achievements for numerous precursors and reference materials. Our company offers a wide range of products, available for sale with a purity of 98% (or 95%) or higher, starting from a minimum quantity of 10mg. We provide short delivery times and will attach HPLC charts with results. Product information is constantly updated, so please feel free to consult us. 【Features】 ■ Custom synthesis for reagents not listed in the catalog ■ Extensive manufacturing experience compliant with GMP ■ Manufacturing support from our subsidiary Nard Chemicals, which has a quality assurance system based on GMP standards ■ Design of compound structures suitable for PET probes and synthesis of derivatives to support early development of PET probes *For more details, please refer to the related links page or feel free to contact us.

  • Other contract services

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Phos-tag technology

By selecting plates, resins, fibers, etc. that combine with the foster tag, separation is possible depending on the number of phosphate groups!

The "Phos-tag technology" is a groundbreaking method for the separation, purification, and detection of phosphorylated substances using Phos-tag. Phos-tag is a functional molecule developed by the Laboratory of Pharmaceutical Molecular Function Science at Hiroshima University, which captures phosphate monoester anions (R-OPO32-) at neutral pH (physiological pH). Our company offers contract analysis using Phos-tag SDS-PAGE, providing strong support for research on protein phosphorylation. Additionally, we synthesize special Phos-tag compounds that have undergone chemical modifications such as various labeling, immobilization to single entities, and amino acid introduction. 【Features of Phos-tag SDS-PAGE】 ■ Enables analysis of substrate protein phosphorylation by kinases ■ Quantitatively visualizes phosphorylated and non-phosphorylated substrates ■ Analyzes the phosphorylation state of proteins within cells ■ Allows for Western blot analysis of target proteins ■ Bands can be excised from the gel after staining for mass spectrometry analysis *For more details, please refer to the related link page or feel free to contact us.

  • Contract Analysis
  • Other contract services

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[Material] Betaine

It is expected that using dyeing techniques will enable more precise detection!

Betaine is a compound with a structure where three alkyl chains are attached to the amino group of an amino acid, possessing both positive and negative charges within the molecule. The alkyl chain portion is hydrophobic, while the zwitterionic part is hydrophilic. "Betaine 5" utilizes the properties of this betaine to enable the high-concentration solubilization of poorly water-soluble dyes. This technology is expected to allow for more precise detection when used in staining techniques such as ELISA. For inquiries regarding product and technology information, please feel free to contact us. 【Features】 ■ Contains both positive and negative charges within the molecule ■ The alkyl chain portion is hydrophobic, while the zwitterionic part is hydrophilic ■ Capable of high-concentration solubilization of poorly water-soluble dyes *For more details, please refer to the related link page or feel free to contact us.

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[Material] Ionic liquid

Achievements in the synthesis of various ionic liquids! We perform custom synthesis of a wide range of ionic liquids.

Ionic liquids have unique properties due to their structural characteristics, such as having almost no vapor pressure, being non-flammable and non-combustible, and having high thermal stability. They are expected to be applied in various uses beyond just solvents. Our company has a track record of synthesizing over 100 types of ionic liquids, ranging from commercially available ones like [BMIM][PF6] to various custom-synthesized ionic liquids that are not listed in reagent catalogs. Moreover, due to their unique properties, ionic liquids are anticipated to be applied not only as new reaction solvents and extraction solvents but also in various fields such as battery materials. Our company has a diverse synthesis record of ionic liquids through methods such as synthesis using autoclaves and anion exchange reactions. 【Features】 ■ Track record of synthesizing over 100 types of ionic liquids ■ Custom synthesis of various ionic liquids *For more details, please refer to the related link page or feel free to contact us.

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[Material] OLED material (Organic EL)

It is also possible to provide ultra-high purity refined products with reduced metal content by performing sublimation purification in a clean room!

At Nard Laboratory Co., Ltd., we offer contract synthesis services for OLED materials (organic EL) that are attracting attention as next-generation displays, excelling in visibility, responsiveness, and energy efficiency. We have a proven track record of synthesizing over several hundred compounds, including metal complexes represented by Alq3, aromatic amine-based materials such as TPD and NPD, phosphorescent materials represented by Ir(ppy)3, and recently popular TADF materials. We can supply synthesis quantities ranging from a few grams to kilograms across various scales. For compounds with unknown synthesis routes, if you provide the structure, we will propose a synthesis route from our side. [Features] - Proven track record of synthesizing over several hundred compounds - If you provide the structure, we will propose a synthesis route - We can also accept research in the form of a fixed period for exploring synthesis routes for new compounds or improving manufacturing processes *For more details, please refer to the related link page or feel free to contact us.

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  • Organic Natural Materials
  • Organic EL

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Organic solar cells

We are conducting the synthesis and purification of dyes based on our extensive knowledge and experience in organic synthesis!

"Organic solar cells" utilize inexpensive materials and have an easy manufacturing process, which is expected to significantly reduce costs compared to silicon solar cells, making them the next generation of solar cells. There are two strong candidates: "dye-sensitized solar cells" and "organic thin-film solar cells," both of which are being promoted by the NARD Institute. "Organic thin-film solar cells" use organic semiconductors such as fullerene and phthalocyanine, and high purity of the compounds is required. Our company conducts the synthesis and purification of dyes based on our extensive knowledge and experience in organic synthesis, and we can also propose synthetic routes for newly designed materials for solar cells. [Features] ■ Synthesis and purification of dyes based on extensive knowledge and experience in organic synthesis ■ Proposals for synthetic routes for newly designed materials for solar cells *For more details, please refer to the related link page or feel free to contact us.

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Organic semiconductor

From sample sales to industrial production! Custom support such as purity enhancement and additional analysis is available.

Organic semiconductors refer to organic materials that exhibit semiconductor properties, with applications expected in field-effect transistors and organic solar cells. At Nard Research Institute, we manufacture and sell high-purity organic semiconductors such as picene using our own sublimation purification equipment. We cater to everything from research sample sales to industrial production, and we offer custom solutions for purity enhancement and additional analysis. Additionally, we produce high-purity organic semiconductors with a purity of over 99.9% using our own sublimation purification equipment. We accommodate everything from research sample sales to industrial production. 【Features】 - Manufacture and sale of high-purity organic semiconductors such as picene - Support from research sample sales to industrial production - Custom solutions available for purity enhancement and additional analysis *For more details, please refer to the related link page or feel free to contact us.

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  • Other semiconductors
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Optical materials

Possesses a track record in the synthesis of coating agents! Capable of handling everything from the exploration of synthesis routes to the establishment of manufacturing processes.

To achieve miniaturization of lenses, it may be necessary to start from the design of the monomers that serve as materials. At Nard Research Institute, we have a track record of synthesizing various acrylic and methacrylic monomers, as well as coating agents like polyamic acid, using the synthetic techniques we have developed so far. Even for compounds with unknown synthetic routes, if you provide the structure, we can assist from the exploration of the synthetic route to the establishment of the manufacturing process. Additionally, our company has experience in synthesizing various acrylic and methacrylic monomers, as well as coating agents such as polyamic acid, not just low molecular weight monomers. [Features] ■ If you provide the structure, we can assist from the exploration of the synthetic route to the establishment of the manufacturing process. *For more details, please refer to the related link page or feel free to contact us.

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  • Coating Agent
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[Material] Medical high polymers and biomaterials

We will examine material development, including considerations from a biochemical perspective! We contribute to our customers' research and development.

Nard Laboratory Co., Ltd. supports the research and development of polymer materials used in environments that come into contact with biological cells such as skin and blood. The development of biocompatible materials is attracting significant attention in the fields of medical devices and regenerative medicine research and development. Surface properties act on the contacting cells, influencing cell adhesion promotion or inhibition, and even the secretion of growth factors due to extracellular stimuli. Our company examines the development of these materials from a biochemical perspective to contribute to our customers' research and development. 【Features】 ■ Prototype development of polymers for coating surfaces of devices and equipment ■ Support for the development of biodegradable polymers ■ Fluorescent labeling of polymer materials and functional molecular labeling (biochemical research reagents) ■ Process development for medical polymers ■ Chemical modification of reactive functional groups on polymers ■ Hydrogel modification *For more details, please refer to the related links page or feel free to contact us.

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  • Other polymer materials
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Flame-retardant material

We can also assist with color matching! We support the development of flame-retardant materials by blending various chemical materials.

Nard Laboratory Co., Ltd. has been involved in the development and commercialization of flame-retardant sheets and heat-resistant ducts in collaboration with product processing companies. The specific flame-retardant properties are achieved by coating with a flame-retardant paint developed by blending inorganic materials based on silicone resin. We also have a track record of developing insulation materials that have been made flame-retardant through bonding with insulating materials. In this way, by providing the flame-retardant technologies we have cultivated so far, we can assist in the examination of flame-retardancy improvements and non-combustibility considerations. 【Features】 ■ Engaged in the development and improvement of protective coatings ■ Possesses a track record in the development of flame-retardant insulation materials ■ Provides assistance in examining flame-retardancy improvements and non-combustibility considerations ■ Holds expertise in chemical synthesis technology ■ Capable of assisting in the synthesis and development of new flame retardants *For more details, please refer to the related link page or feel free to contact us.

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Synthesis of functional materials

We offer a wide range of support, from general materials to new materials such as electronic materials!

Our company offers a wide range of services tailored to customer needs, from early-stage research and small-scale sample synthesis to scale-up considerations and manufacturing. We cover a broad spectrum of fields, from general materials to new materials such as electronic materials. In the area of inorganic compounds, we have a track record in battery and electronic materials, metal nanoparticles, ceramic and carbon materials, and in composite materials, we have experience with radiation dose indicators and various special coatings. 【Features】 ■ Organic reactions: General organic synthesis ■ Polymer reactions: Radical polymerization, ionic polymerization, electrochemical polymerization, condensation, etc. ■ Modification and blending of polymers: Grafting reactions, oxidation reactions, reduction reactions ■ Synthesis and preparation of inorganic compounds: Sol-gel reactions, hydrothermal synthesis ■ Processing: Sintering, calcination, etc. ■ Compositing: Mixing, dispersion, coating *For more details, please refer to the related link page or feel free to contact us.

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[Material] Synthesis in the field of agricultural chemicals and biotechnology

It accommodates various organic synthesis reactions such as dehydration reactions, ozone oxidation, photochemical reactions, and asymmetric synthesis!

Nard Research Institute Co., Ltd. has a rich track record in the synthesis of various compounds, including pharmaceuticals, pesticides, other natural products, and biomolecules (nucleic acids, glycosides, phosphoric esters). We accommodate various organic synthesis reactions, such as low-temperature reactions, anhydrous reactions, ozonolysis, photochemical reactions, and asymmetric synthesis. Even in cases where there is no established synthetic route, we will propose suitable routes by combining new literature database searches with our extensive experience. [Features] - Rich synthesis track record of various compounds - Support for various organic synthesis reactions - Proposal of suitable routes based on our extensive experience *For more details, please refer to the related link page or feel free to contact us.

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Refined Technology: Low Metalization Service

We offer low metalization services for resist materials and organic electronics materials!

In recent years, materials for material science applications, particularly resist materials and materials for organic electronics, are required not only to be of high purity but also to have reduced metal content. Nard Research Institute utilizes various purification technologies, including sublimation purification developed over more than 40 years of experience, to achieve the reduction of each metal component (from ppm to ppb) and meet customer demands. For inquiries or questions regarding product and technology information, please feel free to contact us. 【Features】 ■ Achieves reduction of each metal component (from ppm to ppb) using various purification technologies. *For more details, please refer to the related link page or feel free to contact us.

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  • Other metal materials

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Refinement technology: separation refinement and structural analysis

We also support the HPLC separation of optical active substances using chiral columns!

At the Nard Research Institute, we have been advancing the acquisition of manufacturing technologies and the expansion of separation and purification techniques and equipment in cutting-edge fields such as pharmaceuticals, electronic materials, automotive materials, and bio-related materials. Utilizing all the technologies and equipment we have cultivated so far, we not only support HPLC separation using silica gel, ODS, and GPC columns but also HPLC separation of optically active compounds using chiral columns. Additionally, we possess a mass-triggered HPLC separation device, allowing for the separation of trace components identified by mass spectrometry. The samples obtained through separation undergo structural analysis using analytical instruments such as NMR, LC/MS, GC/MS, and MALDI-TOF/MS, ultimately leading to the synthesis of estimated compounds and the identification and structural determination of unknown substances. 【Features】 ■ Supports HPLC separation of optically active compounds using chiral columns ■ Capable of separating trace components identified by mass spectrometry ■ Ultimately combines separated samples with the synthesis of estimated compounds for the identification and structural determination of unknown substances *For more details, please refer to the related link page or feel free to contact us.

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Synthesis Technology: Metal Complexes

The synthesized metal complex can be analyzed using our analytical instruments such as NMR, XRD, and ICP-OES!

"Metal complexes" exhibit a wide variety of properties, such as catalysts and dye sensitizers, depending on the combination of ligands and metals. Our company conducts commissioned synthesis, including various ligand synthesis and complexation. Additionally, the synthesized metal complexes can be analyzed using techniques such as NMR, XRD, and ICP-OES. [Features] ■ We perform commissioned synthesis that includes various ligand synthesis and complexation. ■ The synthesized metal complexes can also be analyzed using techniques like NMR. ■ We have dark rooms and multiple glove boxes, allowing synthesis under various conditions. *For more details, please refer to the related links page or feel free to contact us.

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  • Other metal materials

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Synthesis Technology: Alkoxysilane Compounds

We have a track record of synthesizing various alkoxysilane compounds and supplying them in quantities of up to several hundred grams!

Alkoxysilane compounds have been used as silane coupling agents for a long time and have recently gained attention as raw materials for unique mesoporous silica structures. Our company has a proven track record of synthesizing various alkoxysilane compounds, with supply capabilities of up to several hundred grams. Please feel free to contact us for inquiries or questions regarding product and technology information. 【Features】 ■ Long-standing use as silane coupling agents ■ Also gaining attention as raw materials for mesoporous silica ■ Proven track record in synthesizing various alkoxysilane compounds ■ Supply capabilities of up to several hundred grams *For more details, please refer to the related link page or feel free to contact us.

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Homogeneous transition metal catalysts in synthetic technology

Wide-ranging support from next-generation rare earth metal complexes to non-metallocene type transition metal catalysts!

Our company is particularly focused on polymerization catalysts, and we have built a track record in synthesizing homogeneous transition metal catalysts starting from ligand synthesis. Based on our extensive knowledge and experience in organic synthesis, we can accommodate not only existing metal complexes but also newly designed metal complexes, as well as next-generation rare earth metal complexes and non-metallocene type transition metal catalysts. [Features] - Particularly focused on polymerization catalysts - Wide-ranging support based on extensive knowledge and experience in organic synthesis *For more details, please refer to the related links page or feel free to contact us.

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  • Other metal materials

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Synthesis Technology: Optical Active Substance

We offer custom synthesis using asymmetric reduction catalysts! Introducing our synthesis technology and optically active compounds.

In the Material Science Research Department Group 6, we synthesize products such as "-3-Hydroxybutanoic" and "-Pentanediol" using asymmetric reduction catalysts. In addition to the compounds listed below, we also offer custom synthesis using asymmetric reduction catalysts. For inquiries or questions regarding product and technology information, please feel free to contact us. 【Compounds】 ■ (R): -3-Hydroxybutanoic Acid Ethylester 98% ee ■ (R): -3-Hydroxybutanoic Acid Methylester 98% ee ■ (S): -3-Hydroxybutanoic Acid Ethylester 98% ee ■ (S): -3-Hydroxybutanoic Acid Methylester 98% ee ■ (2R, 4R): -Pentanediol 98% ee ■ (2S, 4S): -Pentanediol 98% ee *For more details, please refer to the related link page or feel free to contact us.

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Synthesis Technology: Organic Dyes

We have a track record of synthesizing a wide variety of organic dyes, including squarilium-based dyes!

"Organic dyes" are attracting attention as highly efficient light absorbers and key materials for functionalization in the fields of electronic information and medical diagnostics. Our company has a proven track record in the synthesis of a wide variety of organic dyes, including Ru-based sensitizing dyes, phthalocyanine-based dyes, and squarilium-based dyes, utilizing the synthetic techniques we have developed over the years. For compounds with unknown synthetic routes, if you provide the structure, we can propose a synthetic route from our side. [Features] - Proven track record in the synthesis of a wide variety of organic dyes - For compounds with unknown synthetic routes, if you provide the structure, we can propose a synthetic route *For more details, please refer to the related link page or feel free to contact us.

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Synthetic Technology: Molecular Imaging

We will strongly support research and development in the field of molecular imaging!

Molecular imaging refers to a technique that non-invasively visualizes changes in molecular groups within living organisms (such as enzymes, genes, membrane proteins, etc.) and observes them dynamically and quantitatively. A representative method in this field is positron emission tomography (PET), which is well-known in current research. In recent years, technologies utilizing fluorescence and near-infrared light have also been applied in the fields of biochemistry and regenerative medicine. As it lies at the intersection of medicine, pharmacy, and engineering, this field is expected to see further development. Nard Institute will continue to support this area from the standpoint of organic compound development. [Theme] ■ VARGULA LUCIFERIN ■ Fluorescent labeling of organelles *For more details, please refer to the related links page or feel free to contact us.

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Synthesis Technology: Stable Isotope Labeling

Based on our extensive synthesis experience, we can accommodate the labeling of a wide range of compounds!

Our company conducts the synthesis of various compounds, including fluorescent substances such as DOTA, TAMRA, Alexa, Biotin, and stable isotopes like deuterium, 13C, and 15N. We can introduce these compounds to your desired sites and also provide suggestions for compounds tailored to your intended applications. Based on our extensive synthesis experience, we support the labeling of a wide range of compounds, including general organic compounds, glycans, nucleic acids, and more. For inquiries or questions regarding product and technology information, please feel free to contact us. 【Features】 ■ Synthesis of compounds containing stable isotopes ■ Suggestions for compounds tailored to your intended applications ■ Support for the labeling of a wide range of compounds *For more details, please refer to the related link page or feel free to contact us.

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Synthesis Technology: Metal Nanoparticles

It can be dispersed in organic solvents! It is used in various applications across a wide range of industries.

Our company uses a method called the bottom-up approach for the synthesis of metal nanoparticles and the synthesis of composite materials that support metal nanoparticles on a carrier. Compared to the top-down approach, it is possible to achieve a narrower particle size distribution. We have a track record of various synthesis methods and a wide range of elements. Our materials are used in a variety of industries for applications such as conductive materials, magnetic materials, luminescent materials, DDS materials, cosmetic materials, battery materials, and catalyst materials. 【Features】 ■ It is possible to disperse in organic solvents by introducing organic substances onto the particle surface. ■ Compared to the top-down approach, it is possible to achieve a narrower particle size distribution. ■ We have a track record of various synthesis methods and a wide range of elements. ■ We actively try elements and synthesis methods that have not been implemented before. *For more details, please refer to the related link page or feel free to contact us.

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Synthesis Technology: Inorganic Material Synthesis

We can carry out everything from prescription proposals to the analysis of synthetic products! We have a track record of custom synthesis for over 500 compounds.

Our company offers contract synthesis services for inorganic materials, with a track record of over 500 custom syntheses. We can propose synthesis methods not only for those with established procedures but also for requests where only the compound structure is determined and the synthesis method is not. We utilize our in-house know-how and conduct literature research to suggest synthesis formulations. We possess various equipment related to inorganic synthesis and analysis of inorganic materials, allowing us to carry out everything from formulation proposals to analysis of the synthesized products. 【Synthesis Achievements (Excerpt)】 <Methods> ■ Solid-phase method, co-precipitation method, sol-gel method, hydrothermal synthesis method, solvothermal method, melt-quenching method, etc. <Materials> ■ Various solid materials for batteries (positive electrode active materials, negative electrode active materials, solid electrolytes, precious metal-supported catalysts), glass materials, MOF materials, metal nanoparticle materials, catalyst materials, etc. *For more details, please refer to the related link page or feel free to contact us.

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Dendrimers in synthetic technology

We also offer contract synthesis of hyperbranched polymers, which are relatively easier to synthesize than dendrimers.

At Nerd Research Institute, we utilize the fine chemical synthesis technologies accumulated so far to offer contract synthesis and research of dendrimer raw materials (building blocks). By employing various polymerization methods, we provide novel hyperbranched polymers. Additionally, upon request, we can assist in creating dendrimers with new functionalities by combining building blocks into the core. Our company synthesizes new dendrimer raw materials and dendrimers to meet your needs. 【Features】 ■ Synthesis of new dendrimer raw materials and dendrimers ■ Utilization of fine chemical synthesis technologies ■ Acceptance of contract synthesis and research for dendrimer raw materials ■ Also conducting contract synthesis of relatively easier-to-synthesize hyperbranched polymers than dendrimers ■ Providing novel hyperbranched polymers by employing various polymerization methods *For more details, please refer to the related links page or feel free to contact us.

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