ベックマン・コールター List of Products and Services

The Allegra V-15R is a benchtop centrifuge characterized by its high versatility, making it a mainstay in laboratories. With an easy-to-use control panel and ergonomic design, it offers simple and seamless operability. It allows for easy swapping of a rich variety of 10 rotors, enabling it to accommodate various workflows with just one unit. The Allegra V-15R can utilize a diverse range of swing rotors, fixed-angle rotors, and adapters to handle tubes, bottles, and plates of various capacities and shapes, allowing for more efficient centrifugation tasks. With a lineup of 10 rotors and a wide range of adapters, it can support various applications and workflows, from high-throughput screening samples to the separation of cells and blood components. *For more details, please refer to the PDF materials or feel free to contact us.*

• Separation device

If you need a device that allows you to quickly learn how to operate it, is easy to use, and can sort multiple cell populations, the benchtop cell sorter CytoFLEX SRT is the best choice. As the name suggests, the CytoFLEX SRT is a new addition to the well-regarded CytoFLEX family of flow cytometers, designed based on the same optical system. This means it has the performance to support high-sensitivity multicolor applications, and in fact, the CytoFLEX family is used for multicolor analysis in many life science research institutions and pharmaceutical companies. • Excellent sensitivity for multicolor applications • A wide range of easily interchangeable bandpass filters • Easy upgrades through license switching • Intuitive software that facilitates multicolor analysis *For more details about the product, please contact us or download the PDF for more information.

• Other measurement, recording and measuring instruments

The CytoFLEX family is a series of compact and revolutionary flow cytometers and cell sorters that achieve low light loss and high sensitivity through optimal laser excitation and fluorescence detection systems. Utilizing advanced telecommunications technology, the evolving CytoFLEX family further expands researchers' options for cell analysis. The CytoFLEX LX is equipped with up to 6 lasers and 21 colors, broadening the possibilities for research. It minimizes fluorescence spillover with six lasers using a spatially separated axis system. ● By purchasing an activation key, additional lasers and detection channels can be added as needed. ● An optional plate loader is available for high-throughput applications. ● The software includes features compliant with 21 CFR Part 11 for use in regulated environments. ● The configuration of the Violet Side Scatter (VSSC) detector allows for the detection of nanoparticles. *For more details about the product, please contact us or download the PDF for more information.

• Other measurement, recording and measuring instruments

The CytoFLEX family is a series of compact and revolutionary flow cytometers and cell sorters that achieve low light loss and high sensitivity through optimal laser excitation and fluorescence detection systems. Utilizing advanced telecommunications technology, the evolving CytoFLEX family further expands researchers' options for cell analysis. The CytoFLEX S series, equipped with blue, red, purple, and infrared lasers, supports applications using a wider variety of fluorescent dyes with up to 4 lasers and 13 colors. The configuration is determined by the number of activated lasers and detectable fluorescence channels. Initially, you can select the required laser configuration and number of parameters, and in the future, you can activate and add parameters according to the changes in your research. 【Features】 ● The use of Avalanche Photodiode (APD) detectors provides unparalleled sensitivity in the red spectrum and a unique correction workflow. ● The configuration of the Violet Side Scatter (VSSC) detector allows for the detection of nanoparticles. *For more details about the product, please contact us or download the PDF for further information.

• Other measurement, recording and measuring instruments

The "MET ONE 3400+ Series" is a compact airborne particle counter that allows for efficient environmental monitoring compliant with GMP standards. It employs an interactive electronic SOP, making sampling tasks easy to perform. Additionally, administrators can access the device via a web browser on a computer to check sampling results and monitoring progress. The approved final report is granted an electronic signature and can be exported in a secure electronic file format. 【Features】 ■ Integration of automated SOPs and sampling maps ■ Ensures tasks are performed accurately and smoothly, contributing to reduced data errors ■ Direct electronic records obtained from the counter itself ■ Interactive customization of the electronic SOP map ■ Network building capabilities for quick validation using IQ/OQ protocols ■ Data is encrypted, preventing user deletion of records *For more details, please refer to the materials. Feel free to contact us with any inquiries.

• Particle Counter

The "HIAC 9703+" is a laboratory-type liquid particle counter capable of directly measuring a minimum sample volume of 0.1 mL from a vial. It is user-friendly and helps reduce the valuable operator's "working time = cost," while also providing peace of mind regarding software security. This liquid particle counter is equipped with robust data integrity features in compliance with various pharmaceutical regulations. 【Features】 ■ Measurement particle size can be selected from 1.2 to 150 μm across 16 channels ■ Complies with the Japanese Pharmacopoeia "General Test Method 6.07 Test for Insoluble Particles in Injectables" Method 1 (Light Obscuration Particle Counting Method) ■ Automatic execution of JP/USP/EP tests with test report functionality ■ Software compliant with 21 CFR Part 11 (Pharm Spec 3) ■ Connectable to LIMS (Laboratory Information Management System) ■ Achieves measurements from 0.5 to 350 µm by selecting a sensor (MC-05 sensor) that combines light obscuration and light scattering methods ■ Compatible with various solvents (organic solvents, acids, alkalis) as well as water *For more details, please refer to the PDF document or feel free to contact us.

• Other measurement, recording and measuring instruments
• Analytical Equipment and Devices

The "Vi-CELL BLU" is an automated cell viability analyzer that performs the entire process from sample staining to counting and viability assessment. It accurately measures cells in small or large volumes of cell culture media, accommodating everything from research to manufacturing scales. It can be used in many facilities that handle cells, such as biopharma and academia. 【Features】 ■ Fully automated from cell staining to equipment cleaning ■ High-speed measurement ■ Requires a small sample volume ■ Reduced inter-instrument variability ■ Supports multi-sample measurement *For more details, please refer to the PDF document or feel free to contact us.

• Other measurement, recording and measuring instruments
• Analytical Equipment and Devices

The "ANATEL PAT 700" is a user-friendly and easy-to-use new model of TOC analyzer. In addition to online measurements, it can also switch to lab measurements for quality control and other purposes. Even if impurities mix into the manufacturing water line, it is equipped with a standard feature that catches them and automatically collects samples. Verification with HPLC can also be performed later, preparing for potential risks. 【Features】 ■ Equipped with a Japanese color touch panel screen ■ Easy operation through icons ■ Simultaneous display of TOC, conductivity, and temperature during measurement. Conductivity particularly complies with USP645 ■ Equipped with excursion mode ■ Two UV lamps included *For more details, please refer to the PDF materials or feel free to contact us.

• Analytical Equipment and Devices

The "Multisizer 4e" is a precision particle size distribution measurement device that adopts the Coulter principle (electrical sensing zone method) and accurately measures the absolute number and volume of particles using advanced digital technology. To measure particles, it is a high-performance and reliable product that is unaffected by the color, shape, composition, or refractive index of the particles. 【Features】 ■ Particle size distribution measurement range: 0.2 to 1,600 µm ■ Ensures traceability of internationally standardized equivalent spherical diameter values, providing accurate data ■ A newly designed measurement beaker disperses particles uniformly for more accurate measurements ■ Continuous monitoring of the device's status through the optional OQ program ■ The newly designed EZAccess constantly checks the electrolyte level, improving measurement stability ■ Standard Operating Procedure (SOP) functionality allows measurements to be taken under the same conditions at any time *For more details, please refer to the PDF document or feel free to contact us.

• Other measurement, recording and measuring instruments
• Other physicochemical equipment

The CytoFLEX is a high-performance compact flow cytometer that, while being compact, offers high flexibility in the selection of lasers and detectors, allowing for the acquisition of data necessary for cell research with high sensitivity and accuracy. It features a space-saving design with a footprint of 43cm x 43cm and a lightweight design weighing 23kg. 【Features】 ■ The display scale obtained with a high-sensitivity 7-decade logarithmic dynamic range is variable according to the purpose of the experiment. ■ Selectable installation of 488nm, 638nm, and 405nm lasers (up to 3) and the option to choose from 4 to 13 fluorescent detectors. ■ Upgradable built-in plate loader. *For more details about the product, please contact us or download the PDF for more information.

• Other measurement, recording and measuring instruments

RNAdvance Cell v2 is a kit for extracting and purifying total RNA with minimal degradation from cultured cells (both suspension and adherent cells) of fewer than 50,000 cells. It demonstrates a high purification yield of 1.8 μg of total RNA from 50,000 MRC-5 cells, and similarly high yields from cells such as ACHN, HCT116, and PANC1. Furthermore, the purified RNA has a low degree of degradation (RIN>9.4; RNA Integrity Number), and PCR amplification after reverse transcription is also good, making it suitable for various downstream analyses. It is compatible with the automated dispensing system Biomek series from Beckman Coulter, achieving high-throughput purification of 96 samples in 3 hours. If DNA removal is required, DNase I is needed separately. - RNA extraction from 50,000 cultured cells - Supports both DNA/RNA extraction from cultured cells *For more details, please refer to the PDF document or feel free to contact us.*

• Chemicals

SPRIselect is a kit that allows for the easy recovery of DNA fragments of specific lengths ranging from 150 to 800 bp without the need for cutting agarose gels. By adjusting the mixing ratio of the DNA solution and the SPRIselect reagent, it utilizes the property that the size of DNA fragments binding to magnetic beads can be varied, allowing for the selective recovery of desired fragment sizes. The unique purification protocol using SPRI magnetic beads is optimized, completing manual experiments for double size selection in 20 minutes for 8 samples and 25 minutes for 24 samples. It is also compatible with automation using Beckman Coulter's Biomek series automated dispensing system, achieving high-throughput processing of 48 samples in 51 minutes and 96 samples in 1 hour. - Selectively recover DNA fragments of arbitrary sizes from 150 to 800 bp - High reproducibility achieved through stringent quality control *For more details, please refer to the PDF document or feel free to contact us.

• Chemicals

The Beckman Coulter Microfuge series of microcentrifuges is a compact centrifuge specialized for microtubes. The Microfuge 20R offers a powerful cooling capability (maintainable at 4°C) with a maximum processing capacity of 36 tubes, while the non-refrigerated Microfuge 20 is a small centrifuge with a compact footprint that also provides strong cooling capability (maintainable at 4°C) and operates on a 100V power supply. It can centrifuge sizes of 0.25, 0.4, 1.5, and 2.0 mL, and can simultaneously process four 8-strip PCR tubes. It comes standard with a rotor for 24 x 1.5 mL tubes. *For more details, please refer to the PDF document or feel free to contact us.*

• Analytical Equipment and Devices
• centrifuge

The environmentally friendly high-performance high-speed centrifuge Avanti J-26S series is a centrifuge that can be widely used for both high-speed and large-scale centrifugation. With an ecological design that reduces energy consumption, it features a memory function for 30 different programs and allows for the setting of centrifugation programs tailored to user needs with 12 or 13 acceleration and deceleration steps. The fixed-angle rotor JLA-8.1000, which can hold up to 6 x 1,000 mL, is a large-capacity and lightweight rotor made from carbon, making it easy for anyone to use. When equipped with a cell separation elutriation rotor, it enables sorting and washing of cells in solution. *For more details, please refer to the PDF document or feel free to contact us.*

• Analytical Equipment and Devices
• centrifuge

The Optima X series is a next-generation ultracentrifuge that offers user-friendly operation based on ergonomic principles and improves environmental performance by reducing standby power consumption by up to 56% compared to our conventional models. We offer two product lines: the basic Optima XE series, which includes only essential core functions, and the premium Optima XPN series, which supports real-time plotting of operating conditions, remote monitoring and control, centrifugation simulation, and log management, totaling five models. *For more details, please refer to the PDF materials or feel free to contact us.*

• Analytical Equipment and Devices
• centrifuge

AMPure XP is a kit designed for the efficient purification of DNA after various enzymatic reactions such as PCR and ligation. It can purify DNA fragments of over 100 bp for double-stranded DNA and approximately 200 nt for single-stranded DNA, effectively removing unwanted short DNA fragments like primers and adapters, as well as dNTPs and salts that you do not want to carry over to the next reaction. AMPure XP has become the golden standard for DNA cleanup in next-generation sequencing library preparation and is a highly proven kit. - High-yield purification of DNA fragments over 100 bp - Efficient removal of primers, adapters, dNTPs, and salts *For more details, please refer to the PDF document or feel free to contact us.

• Other analyses

CleanSEQ is a fluorescent dye terminator removal purification kit used after Sanger sequencing reactions. Sanger sequencing reaction kits are expensive and are generally used in a diluted form. However, dilution can lead to reduced fluorescence intensity, resulting in decreased sequence read lengths. CleanSEQ allows for high purification yields, which can enhance the signal strength during sequencing. - Efficient removal of unreacted fluorescent dyes and primers - Increased fluorescent signal strength and improved sequence read lengths *For more details, please refer to the PDF document or feel free to contact us.

• Other analyses

DNAdvance is a kit for extracting and purifying DNA from various tissues such as liver, kidney, and mouse tails, as well as from cultured cells. It demonstrates a high purification yield of 33 μg of DNA from 20 mg of liver samples, and similarly high yields from other tissues. Furthermore, the purified DNA has a low degree of degradation (DIN>8; DNA Integrity Number) and shows good PCR amplification, making it ideal for next-generation sequencing library preparation. Additional protocols are available for extraction from oral swabs and saliva. DNAdvance uses unique SPRI magnetic beads to extract DNA with high recovery and purity, and it is also an optimal reagent kit for automation with our laboratory automation system, Biomek. - DNA extraction from 20 mg of tissues such as mouse tails and cultured cells - Capable of DNA extraction from oral swabs and saliva *For more details, please refer to the PDF document or feel free to contact us.

• Other analyses

GenFind V3 is a kit for extracting and purifying DNA from blood (whole blood, plasma, serum, buffy coat) up to 400 μL and from cultured cells. It demonstrates a high purification yield of 12 μg of DNA from 400 μL of EDTA-added whole blood, and similarly high yields under citrate, heparin addition conditions, and freezing storage conditions. It is compatible with the automation of Beckman Coulter's Biomek series automated pipetting systems, achieving high-throughput extraction of 96 samples in about 2 hours. - DNA extraction from 400 μL of whole blood, plasma, and serum - Capable of extracting DNA from filter paper blood, saliva, mouthwash, bacteria, etc. *For more details, please refer to the PDF document or feel free to contact us.

• Other analyses

ChloroPure is a kit for simultaneously extracting and purifying DNA/RNA or total RNA only from plant samples (fresh leaves, freeze-dried leaf punches, powdered seeds, etc.). Plants contain a variety of polysaccharides and secondary metabolites, which make nucleic acid extraction challenging; however, ChloroPure enables the extraction of 7 μg of nucleic acids from a sample of 40 mg (or three 6 mm punches of freeze-dried leaves). It is compatible with the automation of Beckman Coulter's Biomek series automated pipetting systems, achieving high-throughput purification of 96 samples in 45 minutes after the centrifugation step following the lysis process. - Simultaneous extraction of DNA/RNA or RNA from 40 mg of plant leaves or seeds - Stable extraction is possible from leaves and seeds of cotton, sunflower, canola, and more *For more details, please refer to the PDF document or feel free to contact us.

• Other analyses

RNAdvance Tissue is a reagent kit for extracting and purifying RNA with high purity from tissue sections and cultured cells. The gentle extraction process using Beckman Coulter's proprietary SPRI magnetic beads ensures high quality, high yield, and consistently reliable experimental results. 【Features】 ○ A reagent kit developed for the automated extraction and purification of RNA from tissue sections and cultured cells. ○ Compatible with various tissue sections and cultured cells containing soft tissue, lipids, and fibers. ○ Extracts and purifies high-purity RNA. ○ Efficiently removes contaminants including genomic DNA. ○ Does not use organic solvents harmful to humans or the environment. ● For other functions and details, please contact us.

• Other analyses

RNAClean XP is a product of the RNase Free grade of AMPure XP, which is highly regarded for DNA purification in next-generation sequencing library preparation. It can be safely used for the purification of RNA, which is easily degraded by trace amounts of RNase. It is suitable for a wide range of applications centered around enzyme reactions using RNA. The purification protocol using proprietary SPRI magnetic beads is optimized, allowing manual experiments to complete the purification of 96 samples in about 20 minutes. It is also compatible with automation using Beckman Coulter's Biomek series automated pipetting systems. - Purifies RNA or cDNA of approximately 200 nt or longer - Ideal for purification after reactions such as reverse transcription and labeling *For more details, please refer to the PDF materials or feel free to contact us.

• Other analyses

The FormaPure XL series is a kit for extracting and purifying DNA (FormaPure XL DNA), RNA (FormaPure XL RNA), and both DNA/RNA (FormaPure XL Total) from 10 μm sections of FFPE (formalin-fixed paraffin-embedded) tissue, up to 7 slices. High yields of around 10 μg of both DNA and RNA can be obtained from 7 slices of 10 μm FFPE tissue. It is compatible with the automated dispensing system Biomek series from Beckman Coulter, which allows for automation (some manual centrifugation is required), achieving high-throughput purification of DNA extraction from 96 samples in 5 hours and 45 minutes, RNA extraction in 5 hours and 30 minutes, and both DNA/RNA extraction in 6 hours and 45 minutes. - DNA extraction from 7 slices of 10 μm FFPE tissue - DNA and RNA can be separately purified from the same slice (Total) *For more details, please refer to the PDF document or feel free to contact us.

• Other analyses

The analytical ultracentrifuge Optima AUC is the most versatile, rigorous, and precise analytical device for demonstrating the molecular weight and fluid dynamic and thermodynamic properties of not only proteins but also other substances. It can determine the molecular weight, size, shape, and polydispersity of solute particles based on their sedimentation behavior, and it can also analyze interactions between particles in their natural state without the need for a carrier. ●● Advantages of AUC ●● - Sample recovery is possible (non-destructive analysis) - Detection at low concentrations - Small sample volume (minimum amount: sedimentation velocity method 100 μL, equilibrium method 25 μL) - No standard samples required - Simple operability *For more details, please refer to the PDF materials or feel free to contact us.

• Analytical Equipment and Devices

The Avanti J-E is ideal for spaces with limited room due to its compact design. Despite its compactness, it is a powerful unit that can process up to 4,000 mL simultaneously when using the fixed-angle rotor JLA9.1000. - Maximum capacity: 4 x 1,000 mL - Maximum speed: 21,000 rpm - Maximum centrifugal force: 53,300 xg *For more details, please refer to the PDF document or feel free to contact us.

• centrifuge

The high-capacity high-speed cooling centrifuge system Avanti J-HC represents a significant advancement in the large-volume separation of cells and precipitates. It can centrifuge 4 × 2,250 mL, totaling 9 L, at 5,000 rpm and 7,480 ×g, making it a more efficient centrifugation system. Therefore, it is capable of processing 36 L per hour when collecting bacteria. By introducing a disposable sterilized harvest liner system that simplifies sample collection and storage and reduces the cleaning process of bottles, performance and usability are further enhanced. ● Equipped with large-capacity swing rotors and fixed-angle rotors to accommodate a wide range of applications ● Improved operator safety with disposable harvest liners ● Rapid acceleration and deceleration achieved with a unique high-torque SR drive ● Efficient and precise temperature control using environmentally friendly alternative refrigerants *For more details, please refer to the PDF document or feel free to contact us.

• centrifuge

This is a compact multi-tube centrifuge capable of accommodating the class-leading 4x400mL (1.6L), 16 pieces of 50mL conical tubes, and 36 pieces of 15mL conical tubes. By simply changing the rotor, it can quickly transform into a high-capacity multi-tube centrifuge, a plate centrifuge, a 1.5mL microcentrifuge, and a high-speed centrifuge capable of centrifuging 30mL tubes at over 28,000g. This single unit is sufficient for all your centrifugation needs, making it a great space-saver for the lab. **Features** - Class-leading speed and centrifugal force - Easy and quick setup - Flexible and abundant rotor lineup tailored for various applications - Compact size with a width of only 46 cm - BioCertified* swing bucket and fixed-angle rotors - Available in two models: with cooling function (X-30R) and without cooling function (X-30) *For more details, please refer to the PDF document or feel free to contact us.

• Other measurement, recording and measuring instruments

The Allegra 64R high-speed microcentrifuge is the world's fastest microcentrifuge, capable of centrifuging 1.5 mL tubes at 30,000 rpm and 64,000 ×g. It can also centrifuge 50 mL tubes at 21,000 rpm and 41,400 ×g. With various rotors, it can accommodate tubes ranging from 1.5 mL to 85 mL. The Allegra 64R is ideal for processing samples of various volumes with high centrifugal force, making it perfect for the concentration, washing, and classification of fine particles. □ Optimal high centrifugal force for concentration / washing / classification of fine particles □ Ideal for sample preparation for NMR, GC/LC-MS, HPLC, spectrophotometry, ICP, etc. □ Removal of impurities by centrifugation instead of filter filtration High throughput, low dead volume □ Capable of centrifuging various bottles from 0.2 to 85 cc at high speeds *For more details, please refer to the PDF document or feel free to contact us.

• Other measurement, recording and measuring instruments

The new Microfuge 16 from Beckman Coulter features a compact design that won't take up space on your lab bench, allowing for easy spin-down of tubes of various sizes. - Maximum speed: 14,800 rpm - Maximum centrifugal force: 16,163 x g *For more details, please refer to the PDF document or feel free to contact us.

• Other measurement, recording and measuring instruments

The Optima MAX series not only meets various needs with centrifugal forces exceeding 1,000,000 xg and the latest features, but also enhances the traceability of experiments, maintaining a safe and reliable experimental management environment. In fields such as life sciences and nanotechnology, you can choose from the fully functional Optima MAX-XP for fundamental research to quality control, or the Optima MAX-TL, which focuses on ease of use and simplicity, depending on your application. *For more details, please refer to the PDF materials or feel free to contact us.*

• Other measurement, recording and measuring instruments