Training workshops from November to December 2022.

Process model library (reaction, crystallization, wet and dry grinding, spray drying, wet and dry granulation, blending, and tablet compression, etc.)

gPROMS Formulated Products is equipped with a library of process models for operations such as reactions, crystallization, wet and dry milling, spray drying, wet and dry granulation, blending, and tablet compression. In case studies applied to pharmaceutical processes, it enables consistent performance analysis of the entire system from active pharmaceutical ingredient (API) manufacturing through formulation processes to oral absorption risk analysis. ■ Solution crystallization analysis ■ Solid-liquid and solid-gas separation, classification, and granulation process analysis ■ Oral absorption analysis This product was developed with the cooperation of major pharmaceutical companies in Europe and the United States. By using mathematical models of raw materials, unit operations, and product performance, it allows for formulation design aimed at optimizing pharmaceuticals and their manufacturing. It enables faster screening of new formulation candidates against quality attributes, including in vivo performance and manufacturability.

• simulator
• Other analyses
• Analysis Services

For process development, optimal plant design, and operational optimization studies! Simulators for the oil, gas, and chemical industries.

In plant design, equipment sizing, process consideration, and operational optimization, PSE believes that existing process simulators still have room for improvement in terms of convergence for obtaining numerical solutions, constraints of processes they can handle, and customization of process models (model extensibility). The process simulation software developed to meet the needs for more advanced and value-added process plant design and optimization is 'gPROMS Process'. 【Features】 * Libraries for specific applications * Creation of flow sheets using Drag & Drop * High-precision custom model creation and editing functions using gPROMS language * Changes in settings within the same environment from steady-state simulation models to dynamic simulation models * Powerful optimization solution search and analysis functions * Global System Analysis (GSA) * High-Performance Computing (HPC) ★ You can view two "case study materials" available for download. These include examples of achieving high-value product offerings and cost reduction through batch process optimization, as well as successful cases of cost reduction through the optimization of entire plants.

• simulator

For increasing production volume, optimizing operations, scale-up design, cost reduction, energy saving, etc.!

<gPROMS FormulatedProducts Crystallization Process Library> It can be used for various considerations and decision-making in production volume enhancement, operational improvement, and process optimization. To build efficient procedures (recipes) in the crystallization process, we will efficiently carry out operations in the following flow and achieve these within a short period (approximately 1 to 2 months). Modeling → Experiment → Model Verification (Parameter Estimation, Validation) → Process Optimization Consideration → Scale-Up Consideration The ability to automatically perform parameter estimation with the tool is a significant factor in reducing the consideration period. Additionally, since it is a kinetic model (expressing mechanisms in mathematical formulas), the number of parameters is kept to a necessary minimum. Furthermore, tools that automatically optimize cooling temperature reduction methods and patterns, the amount and timing of seed crystals, evaporation rates, and heating patterns are powerful, and scale-up may be conducted in conjunction with CFD (Computational Fluid Dynamics) simulations when necessary.

• Contract Analysis

Kanadebia Co., Ltd. will be exhibiting at the "9th Railway Technology Exhibition 2025 Mass-Trans Innovation Japan 2025" held at Makuhari Messe. This exhibition has been held since 2010 as a comprehensive trade fair where various railway-related technologies, including railway and transportation systems, infrastructure technology, facilities, power, transportation, operation management, vehicles, interiors, and passenger services, come together. Please be sure to check out the "Railway Camera System" offered by Kanadebia. We sincerely look forward to your visit.

On November 20, 2025 (Thursday) and December 2, 2025 (Tuesday) from 11:00 to 14:00, our representative, certified public accountant and tax accountant Koichi Yokoyama, will be speaking at a free webinar hosted by Otsuka Shokai. He will explain important points to be aware of regarding the revised Construction Industry Law. [Construction Industry Law / Public Works Appropriateness Promotion Law] - Prevention of omissions in the description of construction contracts - Obligation to notify "risk" information before the contractor's contract - Mutual exchange of original documents for construction contracts - Digitization of estimates, contracts, and order forms/acceptance letters We are entering an era where contracts must be documented in writing and stored electronically. At Paperlogic, we fully support companies that are transitioning from paper to digital. We also offer free consultations with certified public accountants and tax accountants, so please join us!

We would like to inform you that we will be exhibiting our products at the Membrane Symposium 2025. If you are planning to attend, please feel free to stop by. ❚ Products Scheduled for Exhibition - Artificial Lipid Bilayer Experimental Device | Orbit mini You can easily measure channel activity at the single-molecule level. This device allows for the formation of lipid membranes, reconstitution of membrane proteins, and single-channel measurements in experiments using artificial lipid bilayers, all performed with just a micropipette, enabling functional and structural analysis of target membrane proteins and evaluation of drug effects. - Liposome Preparation Device | Vesicle Prep Pro This is the world's first device that can produce giant unilamellar vesicles (GUVs) with diameters ranging from 1 to 30 μm without organic solvents, using the electroporation method (vibrating hydrated lipid films in an alternating electric field). - Auto Patch Clamp System | Port-a-Patch mini This compact system eliminates the need for a microscope, vibration isolation table, manipulator, and Faraday cage, which are typically required for conventional patch clamp experiments. It allows for easy data acquisition and verification without the need for specialized skills or experience.

Agilent will be exhibiting at the "VACUUM 2025 Vacuum Exhibition"! At Agilent, we offer clean and quiet IDP dry scroll pumps, high-performance and high-compression TwisTorr turbo pumps, ion pumps and controllers optimized for UHV/XHV, and robust and reliable helium leak detectors. Leveraging the technology and expertise cultivated at Varian Vacuum, we respond to our customers' vacuum needs with the value of our products and support based on extensive experience and knowledge. Agilent's pumps, systems, and components enable cutting-edge research in physics, analytical instruments, and nanotechnology, and are also ideal for industrial processes. We invite you to visit the Agilent booth! 【Exhibition Information】 Date: December 3 (Wed) - 5 (Fri), 2025, 10:00 - 17:00 Venue: Tokyo Big Sight, South Hall 2 Booth Number: V-36

＼ Make electrical design easier with comprehensive electrical design CAD Eplan! ／ At this exhibition, under the theme "Data collaboration from design to manufacturing! Significant reduction of lead time in control panel manufacturing through digitalization," we will introduce how Eplan and Rittal can enhance the efficiency of electrical design and control panel manufacturing. We will provide information that can assist you in all processes from design to manufacturing, including the efficiency and automation of electrical design and the manufacturing process of control panels utilizing digital twins. If you are struggling with electrical design or considering the introduction of electrical design CAD, please visit the Eplan and Rittal booth. Date: November 19 (Wed) to November 21 (Fri), 2025, 10:00 AM to 5:00 PM Venue: Tokyo Big Sight, East Hall 4, 4-05 Attendance at "IIFES 2025" requires complete advance registration, so please apply on the official exhibition website. "IIFES 2025" official website: https://iifes.jp/