February 10 ■ Understand from the basics. Easy explanations ■ Accumulation of knowledge beyond AI!? A flavorful physical chemistry model

For the pharmaceutical industry and university pharmacy departments: Materials are currently being provided for the simulation of "continuous production" and the optimization of new drug development.

gPROMS Formulated Products is a modeling tool for solid and powder processes. In cases applied to pharmaceutical processes, it enables consistent performance analysis of the entire system, from active pharmaceutical ingredient (API) manufacturing through formulation processes to risk analysis of oral absorption. Our software has already been implemented by major pharmaceutical companies in Europe, the United States, and Japan. We will send you three simulation materials related to API manufacturing, crystallization, formulation, and oral absorption (Technical Information Association, separate print) by mail (free of charge). 1. Optimal design of API manufacturing and formulation processes using modeling tools 2. Optimization of crystallization processes using simulation and modeling tools 3. Correlation between process parameters and quality characteristics using AI We hope this will be useful as part of further efficiency improvements in "continuous production" and new drug development. If you are interested, please contact us by writing "Request for Process Modeling Materials" in the "Inquiry" section.

• simulator
• Analysis Services

There is a video.

Nova Advanced Cell Science Seminar 2022 [Future Biopharmaceutical Manufacturing] This is a presentation video from the event hosted by Nova Biomedical (September 2022). YouTube video (approximately 16 minutes) Monitoring the operation status of bioreactors with digital twins - Towards building QbD... https://www.youtube.com/watch?v=7JvVQeR7B-I

• simulator
• Other analyses
• Analysis Services

Accelerating further development with digital twins of bioprocesses! There are presentation materials from pharmaceutical, pesticide, and chemical manufacturers.

In the future, in the expanding bio market, why not challenge yourself to improve productivity using the power of software while keeping your existing equipment as is? What products can be created by maximizing the functionality of existing equipment? While satisfying your curiosity about particle size, production volume, and more, we contribute to "reducing development time and costs." By visualizing phenomena that were previously invisible through numbers and graphs, you can deepen your understanding of bioprocesses. <Effects> * Reduction in the number of experiments with the latest modeling features * Shortening of development time through early determination of design space (with validation features) * Risk management during continuous production and scale-up * Optimization of batch crystallization recipes * Monitoring of product quality through digital twins Siemens PSE's bio-related library models (also possible to create digital twins) ■ Bioreactor ■ Fermentation tank ■ Chromatography ■ Filtration ■ Freeze-drying * For more details, please download the PDF, and feel free to reach out if you have any questions.

• simulator
• Analysis Services

Process model library (reaction, crystallization, wet and dry grinding, spray drying, wet and dry granulation, blending, and tablet compression, etc.)

gPROMS Formulated Products is equipped with a library of process models for operations such as reactions, crystallization, wet and dry milling, spray drying, wet and dry granulation, blending, and tablet compression. In case studies applied to pharmaceutical processes, it enables consistent performance analysis of the entire system from active pharmaceutical ingredient (API) manufacturing through formulation processes to oral absorption risk analysis. ■ Solution crystallization analysis ■ Solid-liquid and solid-gas separation, classification, and granulation process analysis ■ Oral absorption analysis This product was developed with the cooperation of major pharmaceutical companies in Europe and the United States. By using mathematical models of raw materials, unit operations, and product performance, it allows for formulation design aimed at optimizing pharmaceuticals and their manufacturing. It enables faster screening of new formulation candidates against quality attributes, including in vivo performance and manufacturability.

• simulator
• Other analyses
• Analysis Services

Pre-testing in simulations allows for risk avoidance in scaling up. We offer consulting services. Monthly contracts available.

The spray dryer allows for the consideration of product quality variation control and equipment scale-up (enlargement) by simulating factors that influence particle size control, moisture content control, and particle shape during the manufacturing process. In modeling, the particle size distribution is calculated based on the Population Balance equation, and the drying process of the particles is also taken into account. Additionally, representing adhesion to the walls is an important requirement in the simulation. With the integration of Siemens' STAR-CCM+, it is possible to analyze the actual gas flow in detail, which can be used for considerations of scale-up and operational improvements. This is an optional feature of gPROMS FormulatedProducts. *For more details, please download the catalog or contact us.

• simulator
• Contract Analysis
• Analysis Services

Visualize continuous processes! For improving quality and reviewing production costs in active pharmaceutical ingredient manufacturing and formulation processes. *We provide support from demo tests to utilization follow-up.

This is a modeling tool developed in collaboration with a U.S. mega-pharma company. Recently, the pharmaceutical industry has been transitioning from batch production to continuous production, and it is being used for process design and control system considerations. It is a model library of gPROMS FormulatedProducts. In continuous production processes, advanced quality management (PAT, QbD, RTRT) becomes possible, as well as the ability to handle small-batch, multi-product production, but at the same time, high-precision process modeling technology becomes essential. If you have any inquiries such as "I want to reduce plant construction costs," "I want to increase production volume at existing plants," or "I want to improve product quality (particle size distribution)," please feel free to contact us! 【Features】 ■ Capable of steady-state and dynamic (dynamic) simulation ■ Easily handles multiple recycle streams ■ Allows for optimization considerations of plant design and operation methods ■ Can identify and estimate process equipment performance from test data ■ Provides graphical representation of batch plant operating procedures ■ Can be linked with crystallization process analysis libraries ■ Can be linked with oral absorption analysis libraries *For more details about the product, please download the PDF from the link below.

• simulator
• Other analyses
• Analysis Services

For increasing production volume, optimizing operations, scale-up design, cost reduction, energy saving, etc.!

<gPROMS FormulatedProducts Crystallization Process Library> It can be used for various considerations and decision-making in production volume enhancement, operational improvement, and process optimization. To build efficient procedures (recipes) in the crystallization process, we will efficiently carry out operations in the following flow and achieve these within a short period (approximately 1 to 2 months). Modeling → Experiment → Model Verification (Parameter Estimation, Validation) → Process Optimization Consideration → Scale-Up Consideration The ability to automatically perform parameter estimation with the tool is a significant factor in reducing the consideration period. Additionally, since it is a kinetic model (expressing mechanisms in mathematical formulas), the number of parameters is kept to a necessary minimum. Furthermore, tools that automatically optimize cooling temperature reduction methods and patterns, the amount and timing of seed crystals, evaporation rates, and heating patterns are powerful, and scale-up may be conducted in conjunction with CFD (Computational Fluid Dynamics) simulations when necessary.

• Contract Analysis

[Speaker] Nobuki Kawaguchi, Executive Chief Scientist, Astamuse Inc., Technology Intelligence Division [Key Lecture Content] "Japan Restart: Winning Strategies and Strategic Necessity for Japanese Companies" is a strategic document that connects the next 30 years of Japan to corporate management and investment decisions, based on the 17 key strategic areas outlined by the Takai administration. The central concepts are "strategic autonomy, strategic necessity, and chokepoints." It features data-driven analysis layered with primary information from over 1 billion innovation data points across 193 countries. [Lecture Items] <Part 1> Introduction: Overall Design and Three Key Concepts <Part 2> Highlights of Each Chapter = A Continuous "Industry Map" (approximately 60 minutes) <Part 3> Chokepoint Candidates and Latest Examples (approximately 40 minutes) Q&A / Business Card Exchange

[Speaker] ENEOS Power Co., Ltd. VPP Business Division VPP Business Planning Group Manager Yoshio Kyoraishi [Key Lecture Content] As one of the means of monetization in the VPP and grid storage battery business, considering entry into the demand-supply adjustment market has become unavoidable. On the other hand, due to rapid changes in the system since the start of trading for all products (April 2024), the difficulty of considering market entry has increased. In this situation, it is important to accurately capture the changes in market systems and predict the future market environment to proceed with considerations. In this lecture, we will organize the means of monetization, market environment, and market systems in the VPP and grid storage battery business, and discuss future prospects. [Lecture Items] 1. Means of Monetization 2. Market Environment 3. Market System 4. Future Prospects 5. ENEOS Power's Business Development 6. Summary 7. Q&A / Business Card Exchange

Takeuchi Kogyo Co., Ltd. will exhibit at the "39th EMC and Noise Control Technology Exhibition," which is part of TECHNO-FRONTIER 2026, held at Tokyo Big Sight from Wednesday, July 15 to Friday, July 17, 2026. Venue: Tokyo Big Sight, West Hall 3 Booth Number: 3-H14

The speed of application development is changing significantly. While the use of cloud, agile methodologies, in-house development, and generative AI is advancing, it has become increasingly difficult to sufficiently mitigate development risks through post-process checks by the security department alone. Additionally, there are expectations for the evolution of security measures through the use of generative AI, and the realization of advanced DevSecOps using AI is anticipated to become important in the future. This seminar will explain the challenges commonly faced when practicing DevSecOps, such as clarifying the lacking security measures, prioritizing those measures, and enhancing DevSecOps through the use of AI. This content is a must-see for those in information systems, security, development, and operations who are struggling with promoting DevSecOps.

We will be exhibiting at TECHNO×FRONTIER 2025 - the 40th Power System Exhibition. Please be sure to visit our booth. Our booth: West Hall 4, NO. 4-B25 Organizer: Japan Management Association https://www.jma.or.jp/tf/outline/power.html