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  4. February 10 ■ Understand from the basics. Easy explanations ■ Accumulation of knowledge beyond AI!? A flavorful physical chemistry model
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  • Feb 08, 2023
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Feb 08, 2023

February 10 ■ Understand from the basics. Easy explanations ■ Accumulation of knowledge beyond AI!? A flavorful physical chemistry model

シーメンス株式会社  gPROMS ポートフォリオ シーメンス株式会社 gPROMS ポートフォリオ
Due to the visit of our management to Japan, we will be holding a seminar with the following title. We will also provide time for questions and answers, so please feel free to join us. <Title> Accumulating Insights Beyond AI!? A Flavorful Physical Chemistry Model Technology Transfer, Scale-Up, and Reduction of Experimental Numbers Using Modeling ~ From Pharmaceuticals and Biotech to the Food Industry ~ We plan to present on formulation processes, as well as topics related to biotech and food. * The seminar will be conducted in English, but Japanese interpretation will be available as needed. <Date and Time> February 10 (Friday) 15:00 - 17:30 <Expected Visitors> Sean BERMINGHAM – Vice President, Formulated Products Kevin HEALY – Global Commercial Director If you wish to participate, please provide your "organizational email address" and apply through the "Contact" section below, stating "Request to Participate in the February 10 Seminar." * Applications will be accepted until the morning of the event.
Date and time Friday, Feb 10, 2023
03:00 PM ~ 05:30 PM
Capital Our conference room (approximately an 8-minute walk from Shin-Yokohama Station). Please refer to the attached map. 11th floor conference room, Arena Tower, 3-1-9 Shin-Yokohama, Kohoku Ward, Yokohama City.
Entry fee Free
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シーメンス株式会社アリーナタワー アクセス (002).pdf[186425]

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Prescription design and formulation process development by model 'gFORMULATE'

For the pharmaceutical industry and university pharmacy departments: Materials are currently being provided for the simulation of "continuous production" and the optimization of new drug development.

gPROMS Formulated Products is a modeling tool for solid and powder processes. In cases applied to pharmaceutical processes, it enables consistent performance analysis of the entire system, from active pharmaceutical ingredient (API) manufacturing through formulation processes to risk analysis of oral absorption. Our software has already been implemented by major pharmaceutical companies in Europe, the United States, and Japan. We will send you three simulation materials related to API manufacturing, crystallization, formulation, and oral absorption (Technical Information Association, separate print) by mail (free of charge). 1. Optimal design of API manufacturing and formulation processes using modeling tools 2. Optimization of crystallization processes using simulation and modeling tools 3. Correlation between process parameters and quality characteristics using AI We hope this will be useful as part of further efficiency improvements in "continuous production" and new drug development. If you are interested, please contact us by writing "Request for Process Modeling Materials" in the "Inquiry" section.

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Digital Twin of Bioreactor - Building QbD

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Nova Advanced Cell Science Seminar 2022 [Future Biopharmaceutical Manufacturing] This is a presentation video from the event hosted by Nova Biomedical (September 2022). YouTube video (approximately 16 minutes) Monitoring the operation status of bioreactors with digital twins - Towards building QbD... https://www.youtube.com/watch?v=7JvVQeR7B-I

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gPROMS Bio Series / Challenging productivity improvement with existing equipment

Accelerating further development with digital twins of bioprocesses! There are presentation materials from pharmaceutical, pesticide, and chemical manufacturers.

In the future, in the expanding bio market, why not challenge yourself to improve productivity using the power of software while keeping your existing equipment as is? What products can be created by maximizing the functionality of existing equipment? While satisfying your curiosity about particle size, production volume, and more, we contribute to "reducing development time and costs." By visualizing phenomena that were previously invisible through numbers and graphs, you can deepen your understanding of bioprocesses. <Effects> * Reduction in the number of experiments with the latest modeling features * Shortening of development time through early determination of design space (with validation features) * Risk management during continuous production and scale-up * Optimization of batch crystallization recipes * Monitoring of product quality through digital twins Siemens PSE's bio-related library models (also possible to create digital twins) ■ Bioreactor ■ Fermentation tank ■ Chromatography ■ Filtration ■ Freeze-drying * For more details, please download the PDF, and feel free to reach out if you have any questions.

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FP.png

Modeling tool for solid and powder processes 'gFORMULATE'

Process model library (reaction, crystallization, wet and dry grinding, spray drying, wet and dry granulation, blending, and tablet compression, etc.)

gPROMS Formulated Products is equipped with a library of process models for operations such as reactions, crystallization, wet and dry milling, spray drying, wet and dry granulation, blending, and tablet compression. In case studies applied to pharmaceutical processes, it enables consistent performance analysis of the entire system from active pharmaceutical ingredient (API) manufacturing through formulation processes to oral absorption risk analysis. ■ Solution crystallization analysis ■ Solid-liquid and solid-gas separation, classification, and granulation process analysis ■ Oral absorption analysis This product was developed with the cooperation of major pharmaceutical companies in Europe and the United States. By using mathematical models of raw materials, unit operations, and product performance, it allows for formulation design aimed at optimizing pharmaceuticals and their manufacturing. It enables faster screening of new formulation candidates against quality attributes, including in vivo performance and manufacturability.

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Spray Drying Spray Dryer Model

Pre-testing in simulations allows for risk avoidance in scaling up. We offer consulting services. Monthly contracts available.

The spray dryer allows for the consideration of product quality variation control and equipment scale-up (enlargement) by simulating factors that influence particle size control, moisture content control, and particle shape during the manufacturing process. In modeling, the particle size distribution is calculated based on the Population Balance equation, and the drying process of the particles is also taken into account. Additionally, representing adhesion to the walls is an important requirement in the simulation. With the integration of Siemens' STAR-CCM+, it is possible to analyze the actual gas flow in detail, which can be used for considerations of scale-up and operational improvements. This is an optional feature of gPROMS FormulatedProducts. *For more details, please download the catalog or contact us.

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Powder process simulation software

Visualize continuous processes! For improving quality and reviewing production costs in active pharmaceutical ingredient manufacturing and formulation processes. *We provide support from demo tests to utilization follow-up.

This is a modeling tool developed in collaboration with a U.S. mega-pharma company. Recently, the pharmaceutical industry has been transitioning from batch production to continuous production, and it is being used for process design and control system considerations. It is a model library of gPROMS FormulatedProducts. In continuous production processes, advanced quality management (PAT, QbD, RTRT) becomes possible, as well as the ability to handle small-batch, multi-product production, but at the same time, high-precision process modeling technology becomes essential. If you have any inquiries such as "I want to reduce plant construction costs," "I want to increase production volume at existing plants," or "I want to improve product quality (particle size distribution)," please feel free to contact us! 【Features】 ■ Capable of steady-state and dynamic (dynamic) simulation ■ Easily handles multiple recycle streams ■ Allows for optimization considerations of plant design and operation methods ■ Can identify and estimate process equipment performance from test data ■ Provides graphical representation of batch plant operating procedures ■ Can be linked with crystallization process analysis libraries ■ Can be linked with oral absorption analysis libraries *For more details about the product, please download the PDF from the link below.

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Crystal analysis simulation software

For increasing production volume, optimizing operations, scale-up design, cost reduction, energy saving, etc.!

<gPROMS FormulatedProducts Crystallization Process Library> It can be used for various considerations and decision-making in production volume enhancement, operational improvement, and process optimization. To build efficient procedures (recipes) in the crystallization process, we will efficiently carry out operations in the following flow and achieve these within a short period (approximately 1 to 2 months). Modeling → Experiment → Model Verification (Parameter Estimation, Validation) → Process Optimization Consideration → Scale-Up Consideration The ability to automatically perform parameter estimation with the tool is a significant factor in reducing the consideration period. Additionally, since it is a kinetic model (expressing mechanisms in mathematical formulas), the number of parameters is kept to a necessary minimum. Furthermore, tools that automatically optimize cooling temperature reduction methods and patterns, the amount and timing of seed crystals, evaporation rates, and heating patterns are powerful, and scale-up may be conducted in conjunction with CFD (Computational Fluid Dynamics) simulations when necessary.

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Company Overview Siemens Process Systems Engineering

Company Overview Siemens Process Systems Engineering

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Exhibition Information : AUTOMOTIVE ENGINEERING EXPOSITION 2026 YOKOHAMA

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Dear Sir or Madam, We hope this message finds you well and that your company continues to prosper. FUKUDA will be exhibiting at the AUTOMOTIVE ENGINEERING EXPOSITION 2026 YOKOHAMA. At this exhibition, we will be showcasing testing equipment such as Air Leak Tester for EV and Equipment Mounted Type Hydrogen Leak Detector. We sincerely hope you will take this opportunity to visit us. Yours sincerely, [Official Site] https://aee.expo-info.jsae.or.jp/en/yokohama/ [DATES] Wednesday, May 27, through Friday, May 29, 2026 10:00 a.m. - 5:00 p.m. [VENUE] PACIFICO Yokohama, Exhibition Hall, Booth No. 274 ※Online Exposition Website:Tuesday, May 19, through Tuesday, June 9, 2026

May 28, 2026

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Industrial Open Network Exhibition

[Event Announcement] Information on Exhibiting at the "Industrial Open Network Exhibition 2026"

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We will be exhibiting at the "Industrial Open Network Exhibition" held in July (Osaka) and September (Tokyo). The Industrial Open Network Exhibition is a trade show focused on industrial network technologies held in Japan, showcasing network technologies, products, and solutions in the fields of manufacturing and factory automation. Various demonstrations and seminars will be held at the venue to introduce practical applications and implementation effects that are useful on-site. In our seminar, we will discuss a solution that prevents communication troubles during implementation and ensures stable operation by selecting industrial network cards and verified PCs as a set. We will clearly present the benefits of set selection and specific usage examples. Additionally, at our exhibition booth, we will display various industrial network card products, including the industrial PCs introduced in the seminar. We will propose products and solutions that are beneficial to your business, so please stop by. ■ For more details, visit: https://www.advanet.co.jp/mec-events/industrial-open-network-fair-2026/

May 26, 2026

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Seminar on How to Choose Salesforce Integration Methods - Tools for Integrating Internal Systems and Data

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This seminar will provide a detailed explanation of how to integrate data between Salesforce and other systems. There are three methods for data integration with Salesforce: the "Data Loader," which is provided free of charge by Salesforce, the "Web API" developed individually, and the highly extensible "Data Integration Tools (EAI Tools)." We will compare the advantages and disadvantages of each method and provide tips for finding the most suitable integration method for your company's needs, incorporating actual case studies. <Recommended for> - Those struggling with data integration between Salesforce and core systems - Those facing challenges with on-site workload that hinder the effective use of Salesforce - Those who want to easily integrate data with peripheral systems

May 26, 2026

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Notice of Participation in FOOMA JAPAN 2026 [Anritsu]

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Anritsu will exhibit at FOOMA JAPAN 2026. We will showcase various products, including an X-ray inspection machine with a learning AI inspection option and an odor inspection machine. A VR demonstration of the "NIR Tablet Inspection Device Ariphas," which was displayed at Interphex Japan, will also be conducted. <Exhibition Information> Name: FOOMA JAPAN 2026 Dates: June 2 (Tuesday) to June 5 (Friday), 2026 Location: Tokyo Big Sight Our Booth: E7-33-11 <Featured Exhibits> ■ NIR Tablet Inspection Device Ariphas (VR Demonstration) ■ X-ray Inspection Machine XR76 Series ■ Weight Sorting Machine with Metal Detection ■ Odor Inspection Machine ■ Rapid Measurement Device for General Bacteria and E. coli - Macro Tech, etc. Please register for your visit on the official website. We look forward to seeing you there.

May 26, 2026

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OTRS Webinar

OTRS Webinar "Advanced Shooting Techniques and Device Utilization Strategies for Long Durations and Challenging Locations"

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How to capture narrow spaces, difficult locations where filming is not easy, and long scenes exceeding one hour. From selecting the latest devices (such as wearables) to advanced filming techniques that avoid failure, and smoothly linking data to OTRS, we provide a thorough explanation of real-world strategies for tackling these challenges! Recommended for those facing such issues! - There are locations, such as between equipment or in clean rooms, where filming with a standard camera is difficult. - Video data from long processes is heavy, making it challenging to import and manage in OTRS. - The angles and quality of the footage during filming are poor, making it difficult to utilize for later video analysis (decomposition).

May 26, 2026

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