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  1. Home
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  3. アジレント・テクノロジー株式会社
  4. Announcing an LC system for online monitoring of bioprocesses for the pharmaceutical industry.
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  • Dec 21, 2023
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Dec 21, 2023

Announcing an LC system for online monitoring of bioprocesses for the pharmaceutical industry.

アジレント・テクノロジー株式会社 アジレント・テクノロジー株式会社
We are pleased to announce the launch of the "Agilent 1290 Infinity II Bio Online LC System," an online liquid chromatography (LC) system designed for real-time bioprocess monitoring in the pharmaceutical industry. Online LC is a system that automatically collects samples directly from the manufacturing process and injects them into the LC for analysis. Compared to conventional offline LC systems found in analytical laboratories, it eliminates the hassle of sampling and sample storage, allowing for real-time monitoring of process conditions. This enables rapid feedback, facilitating process optimization and troubleshooting. Bio LC refers to LC systems suitable for the analysis of antibodies, peptides, and oligonucleotides. Bio LC provides high precision and reproducibility in the separation and quantification of biomolecules due to its biocompatible materials and low dead volume design. Bio LC is widely used for the analysis of biomolecules such as proteins, peptides, nucleic acids, and sugars. For more product details, please check the "Related Links" below.
LC system for online monitoring of bioprocesses for the pharmaceutical industry.
LC system for online monitoring of bioprocesses for the pharmaceutical industry.
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ca01_bio_online_lc.pdf[548854]

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Online LC Solutions
Online LC is a system that automatically collects samples from the manufacturing process and injects them directly into LC for analysis. Compared to conventional offline LC in analytical labs, it eliminates the hassle of sampling and sample storage, allowing for real-time monitoring of the process status. This provides rapid feedback, making process optimization and troubleshooting easier.

Related product

500x500_onlineLC.jpg

Bio Online LC, capable of real-time bioprocess monitoring.

Supports PAT, process control, automation, and remote operation through bio-compatible functionality and real-time bioprocess monitoring.

Reliable Process Monitoring with Online LC The InfinityLab online LC solution allows for the automation of process monitoring. With real-time data availability, you can quickly grasp the status of the process and control it accurately. A key technology of this solution is the online sample manager, which easily associates analysis with the process. This module can automatically analyze samples either injected directly or taken from flow reactors, batch reactors, upstream bioreactors, or downstream purification devices.

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  • Analytical Equipment and Devices
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Flexibly customize the system to accommodate various LC issues in analysis.

Advanced modular design allows for flexible customization of the system to address various analytical liquid chromatography (LC) challenges.

Expand versatility! When concentrating target components, removing matrix compounds, or wanting to lower the detection limit for trace substances in water, the 1260 and '1290 Infinity II Online SPE System' can flexibly customize the system to meet various LC challenges through advanced modular design. The online SPE solution is based on the 1290 Infinity Flexible Cube, which can accommodate reusable SPE cartridges and up to two valves. 【Features】 ■ Built-in pump function of the Agilent 1290 Infinity Flexible Cube for transferring samples to the cartridge ■ Up to three solvents can be switched using the built-in solvent selection valve according to online SPE conditions ■ The online SPE starter set allows for easy upgrades to applications such as direct injection *For more details, please refer to the related link page or feel free to contact us.

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LC to improve the rapid understanding and management of processes through real-time data.

Promoting method development! It is a process analysis liquid chromatography (LC) system that enables automatic process monitoring.

"1260 Infinity II Prime Online LC System" Achieves rapid understanding and management of processes through real-time data. Supports direct injection for high-speed process monitoring. Additionally, it is equipped with a sample retention function targeting dilution, automatic sample pretreatment stages, multi-method analysis, and offline quality control for sample storage. 【Features】 ■ Dedicated Process Analytical Technology (PAT) tool ■ Introduction of hybrid injection technology to LC ■ Maximizes management of process samples and promotes method development ■ Compatible with OpenLab CDS 2, designed for fractionation applications *For more details, please refer to the related links or feel free to contact us.

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Related catalog(2)

Agilent InfinityLab LC Series HPLC & UHPLC Comprehensive Catalog 2023-2024 Edition

Agilent InfinityLab LC Series HPLC & UHPLC Comprehensive Catalog 2023-2024 Edition

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Agilent 1260 Infinity II Prime Online LC System

Agilent 1260 Infinity II Prime Online LC System

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アジレント・テクノロジー株式会社
Testing, Analysis and Measurement
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Notice of Golden Week Holiday Closure

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Thank you very much for your continued support. We, at Marpos Co., Ltd., regret to inform you that we will be closed during the following period. Closure Period: From Saturday, April 25, 2026, to Wednesday, May 6, 2025. Inquiries received during the closure period will be answered sequentially after Thursday, May 7. We apologize for any inconvenience this may cause and appreciate your understanding.

Apr 13, 2026

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Notice of Closure During the 2026 Golden Week Period

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We would like to inform you about the business hours during the GW period, as well as order, shipping, and support services. Please download the PDF to check the schedule. ■ Regarding Orders 1) Orders can be placed at any time on the 【FOSS WEBSHOP】. Stock will be prioritized. 2) Please specify your "desired delivery date" when placing an order. 3) Due to expected high order volume and shipping delays before and after the holiday, please make your requests with ample time. ■ Regarding Customer Support For any malfunctions or issues during the holiday... Customers with maintenance contracts should contact the dedicated number for after-hours support. Other customers can reach us via email. Please provide details such as "model name," "serial number," "symptoms," and "contact person's name." Our customer support will contact you in the order of receipt. E-Mail: service@foss.co.jp

Apr 13, 2026

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[Cast Iron Repair] We will repair cracks that have occurred in metal equipment without applying heat.

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The "Mechanical Stitching Method" by Nichinichisui Road Machinery Co., Ltd. is a new technique that allows for the repair of metal cracks without the application of heat. By using special bolts and reinforcement plates, cracks are physically removed, and repairs are made without causing any thermal impact on the base material. Repairs can be carried out in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. ◎ For more details, please contact us. ◎ If a detailed technical explanation is needed, please contact us.

Apr 13, 2026

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【Metal Crack Repair】We repair cracks in metal products without applying heat.

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The "Mechanical Stitch Method" by Nichinichisui Road Machinery Co., Ltd. is a new technique that allows for the repair of metal cracks without the application of heat. By using special bolts and reinforcement plates, cracks are physically removed, and repairs are made without causing any thermal impact to the base material. Repairs can be carried out in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. ◎ For more details, please contact us. ◎ If a detailed technical explanation is needed, please contact us.

Apr 13, 2026

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SPACECOOL will exhibit at the comprehensive exhibition for electrical materials and housing equipment, "Jumbo Surprise Exhibition," at two locations in Tokyo and Osaka.

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SPACECOOL Inc., which researches, develops, and sells the radiation cooling material "SPACECOOL" that releases heat into space to achieve zero-energy cooling, will exhibit at the "Jumbo Surprise Exhibition," a comprehensive trade fair for electrical materials and housing equipment, held at Tokyo Big Sight from April 17 (Friday) to April 18 (Saturday), 2026, and at Intex Osaka from April 24 (Friday) to April 25 (Saturday), 2026. This material is a new technology that enables zero-energy cooling by converting heat into infrared radiation and releasing it into space, without using any external power. By implementing it in outdoor air conditioning units and outdoor electrical equipment, it helps suppress internal temperature rises, contributing to stable operation of devices and reduction of air conditioning energy consumption, and is being recognized as a new carbon-neutral technology. Its energy-saving performance has been acknowledged, and this material received the 2025 Energy Conservation Award. When you visit the venue, please stop by our booth. Our booth number is 972 (common for both Tokyo and Osaka). We will continue to work towards expanding the social implementation of SPACECOOL to contribute to the stable operation of outdoor equipment and air conditioning units, as well as to reduce air conditioning energy consumption and CO2 emissions.

Apr 13, 2026

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