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  1. Home
  2. Testing, Analysis and Measurement
  3. アジレント・テクノロジー株式会社
  4. Announcing an LC system for online monitoring of bioprocesses for the pharmaceutical industry.
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  • Dec 21, 2023
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Dec 21, 2023

Announcing an LC system for online monitoring of bioprocesses for the pharmaceutical industry.

アジレント・テクノロジー株式会社 アジレント・テクノロジー株式会社
We are pleased to announce the launch of the "Agilent 1290 Infinity II Bio Online LC System," an online liquid chromatography (LC) system designed for real-time bioprocess monitoring in the pharmaceutical industry. Online LC is a system that automatically collects samples directly from the manufacturing process and injects them into the LC for analysis. Compared to conventional offline LC systems found in analytical laboratories, it eliminates the hassle of sampling and sample storage, allowing for real-time monitoring of process conditions. This enables rapid feedback, facilitating process optimization and troubleshooting. Bio LC refers to LC systems suitable for the analysis of antibodies, peptides, and oligonucleotides. Bio LC provides high precision and reproducibility in the separation and quantification of biomolecules due to its biocompatible materials and low dead volume design. Bio LC is widely used for the analysis of biomolecules such as proteins, peptides, nucleic acids, and sugars. For more product details, please check the "Related Links" below.
LC system for online monitoring of bioprocesses for the pharmaceutical industry.
LC system for online monitoring of bioprocesses for the pharmaceutical industry.
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ca01_bio_online_lc.pdf[548854]

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Online LC Solutions
Online LC is a system that automatically collects samples from the manufacturing process and injects them directly into LC for analysis. Compared to conventional offline LC in analytical labs, it eliminates the hassle of sampling and sample storage, allowing for real-time monitoring of the process status. This provides rapid feedback, making process optimization and troubleshooting easier.

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500x500_onlineLC.jpg

Bio Online LC, capable of real-time bioprocess monitoring.

Supports PAT, process control, automation, and remote operation through bio-compatible functionality and real-time bioprocess monitoring.

Reliable Process Monitoring with Online LC The InfinityLab online LC solution allows for the automation of process monitoring. With real-time data availability, you can quickly grasp the status of the process and control it accurately. A key technology of this solution is the online sample manager, which easily associates analysis with the process. This module can automatically analyze samples either injected directly or taken from flow reactors, batch reactors, upstream bioreactors, or downstream purification devices.

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Flexibly customize the system to accommodate various LC issues in analysis.

Advanced modular design allows for flexible customization of the system to address various analytical liquid chromatography (LC) challenges.

Expand versatility! When concentrating target components, removing matrix compounds, or wanting to lower the detection limit for trace substances in water, the 1260 and '1290 Infinity II Online SPE System' can flexibly customize the system to meet various LC challenges through advanced modular design. The online SPE solution is based on the 1290 Infinity Flexible Cube, which can accommodate reusable SPE cartridges and up to two valves. 【Features】 ■ Built-in pump function of the Agilent 1290 Infinity Flexible Cube for transferring samples to the cartridge ■ Up to three solvents can be switched using the built-in solvent selection valve according to online SPE conditions ■ The online SPE starter set allows for easy upgrades to applications such as direct injection *For more details, please refer to the related link page or feel free to contact us.

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LC to improve the rapid understanding and management of processes through real-time data.

Promoting method development! It is a process analysis liquid chromatography (LC) system that enables automatic process monitoring.

"1260 Infinity II Prime Online LC System" Achieves rapid understanding and management of processes through real-time data. Supports direct injection for high-speed process monitoring. Additionally, it is equipped with a sample retention function targeting dilution, automatic sample pretreatment stages, multi-method analysis, and offline quality control for sample storage. 【Features】 ■ Dedicated Process Analytical Technology (PAT) tool ■ Introduction of hybrid injection technology to LC ■ Maximizes management of process samples and promotes method development ■ Compatible with OpenLab CDS 2, designed for fractionation applications *For more details, please refer to the related links or feel free to contact us.

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Related catalog(2)

Agilent InfinityLab LC Series HPLC & UHPLC Comprehensive Catalog 2023-2024 Edition

Agilent InfinityLab LC Series HPLC & UHPLC Comprehensive Catalog 2023-2024 Edition

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Agilent 1260 Infinity II Prime Online LC System

Agilent 1260 Infinity II Prime Online LC System

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アジレント・テクノロジー株式会社
Testing, Analysis and Measurement
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Please let us know your concerns regarding leaks. We may have some suggestions for you. Leak tests, leakage tests, leak inspections, leak detection, container integrity tests, packaging integrity tests...

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Fukuda Corporation has been pursuing leak detection for 60 years and is dedicated to advancing the future of leak testing. 【 Supporting Various Leak Tests: Air Leak Test / Gas Leak Test (Hydrogen Gas, Helium Gas) 】 We develop, manufacture, and sell leak testing equipment to inspect airtightness and sealing performance. We will propose suitable testers and devices for each inspection target. 【 Target Industries and Examples of Inspection Targets 】 - Automotive Industry: Engines, FC components, valves and piping, various parts - Electronic Components Industry: Smartphones, keyless switches, various small sensors - Pharmaceuticals / Food / Cosmetics Industry: Bottle containers, syringes, vials, eye drop containers, pillow packaging, PTP packaging We will propose the most suitable leak testers for each industry. 【 ISO Certification 】JIS Q 9001:2015 (ISO 9001:2015)

Aug 21, 2026

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Fukuda's Technology Column

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This is a collection of links to Fukuda's technical columns. It covers various topics related to leak tests and more... Please check the related links for more information.

Aug 21, 2026

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Hyper CLT flooring panel

Utilized for temporary roads on slopes | Wood CLT "Hyper CLT Paving Slabs"

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In civil engineering sites such as mountainous areas and construction sites, it may be necessary to use wooden boards on slopes or inclined access roads. Hyper CLT boards are civil engineering materials utilizing wood CLT, which can be laid not only on flat ground but also on sloped terrain. They can be used for temporary roads, access routes, heavy machinery entry paths, and measures against muddy conditions, creating a driving environment that takes advantage of the unique surface characteristics of wood. The 5×10 board weighs approximately 230 kg, and the 5×20 board weighs about 460 kg, making them lightweight and easy to install and remove even with small machinery, which is a notable feature for maneuverability in narrow sites. This wooden board is registered as a technology under the Ministry of Land, Infrastructure, Transport and Tourism's NETIS system as "TH-250021-A," and can also be utilized for safety measures and innovative ideas in public works.

Aug 21, 2026

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Metal Crack Repair: MS Method for Repairing Cracks and Fractures in Machinery Equipment

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Metal cracks are one of the concerns in equipment maintenance operations. Repairs using conventional welding methods can alter the base material around the crack due to heat, leading to residual stress and deformation, which always carries the risk of "crack recurrence" or "secondary damage." Hinode Waterworks Equipment Co., Ltd.'s "Mechanical Stitching Method" is a new technique that allows for the repair of metal cracks without applying heat. By using special bolts and reinforcement plates, the crack is physically removed without affecting the base material with heat. Repairs can be performed even in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. For more details, please contact us or download the catalog.

Aug 21, 2026

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Casting sand mold 3D printer prototype production

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● The production time for cast prototypes can be shortened! Since model making is not required, the production time for prototypes, which previously took about a month, can be significantly reduced. ● Model costs can be reduced! By directly producing sand molds from 3D data, there is no need for model production costs. If changes to the model are necessary, they can be addressed by modifying the 3D data. ● Similar products with different shapes and dimensions can be prototyped simultaneously! Different products, such as similar shapes or varying dimensions, can be molded at the same time in one molding process. This allows for the verification of multiple types in a short period.

Aug 21, 2026

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