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  4. CPhI Japan Exhibition & Seminar!
SEMINAR_EVENT
  • Apr 02, 2024
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Apr 02, 2024

CPhI Japan Exhibition & Seminar!

Unchained Labs (アンチェインドラブズ) Unchained Labs (アンチェインドラブズ)
CPhI Japan Exhibition & Seminar! April 17 (Wednesday) - 19 (Friday) @ Tokyo Big Sight Unchained Labs, Inc. will be exhibiting in the biopharmaceutical zone at CPhI Japan this year as well. This time, we will also hold an exhibitor seminar on the first day! Please come visit our booth at Tokyo Big Sight. <Exhibitor Seminar> April 17 (Wednesday) 11:30 - 12:00 【5B】 "Unchained Ecosystem Supporting Drug Development and Scale-Up with Lipid Nanoparticles" *No prior reservation required, free of charge.
Date and time Wednesday, Apr 17, 2024 ~ Friday, Apr 19, 2024
Capital Venue: Tokyo Big Sight Booth: 4X-12 (Hall 4, BioPharma Zone)
Entry fee Free
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Protein and Nucleic Acid Quality Evaluation Device 'STUNNER'

Quality assessment of proteins, nucleic acids, AAV, LNP, etc. is possible with trace amounts and high throughput.

"Stunner" is a product that allows simultaneous acquisition of UV/Vis concentration, dynamic light scattering (DLS), and static light scattering (SLS) data from a 2μL identical sample. It enables detailed investigation of AAV and adenoviruses to measure total capsid titer and Empty/Full ratios, as well as to obtain payload concentration and size data of lipid nanoparticles all at once. You can analyze concentration, hydrodynamic size, polydispersity, and the presence of aggregates collectively, allowing you to assess the quality of proteins. This way, you can immediately determine whether your AAV, adenoviruses, lipid nanoparticles, or proteins are suitable for your purposes. [Features] ■ Measure up to 96 samples in a batch in 60 minutes*/12 minutes** *When measured by DLS **When measured by UV/Vis only [Applications] ■ AAV/Adenovirus capsid titer ■ AAV/Adenovirus Empty/Full ratio ■ Lipid nanoparticle (LNP) payload amount ■ Aggregate measurement ■ Concentration measurement ■ Sizing & polydispersity ■ B22 & kD *For more details, please refer to the PDF document or feel free to contact us.

  • Other protein analysis

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All-in-One Protein Structure Stability Evaluation System 'UNCLE'

Simultaneous measurement of 12 applications such as thermal stability, sizing, and viscosity from trace samples.

"Uncle" is a product that allows for the acquisition of more data with a small amount of protein. The required sample volume is only 9μL. By combining three different measurement modes—fluorescence, SLS, and DLS—it is easy to evaluate the optimal formulation and the stability of proteins or viral vectors. 【Features】 ■ Measure up to 48 samples in as little as about 2 hours with just 9μL. 【Applications】 ■ Tm & Tagg ■ Tm via SYPRO DSF ■ Isothermal stability ■ Sizing and polydispersity ■ Sizing via thermal gradient ■ Refolding measurements ■ Viscosity ■ kD ■ B22 ■ G22 ■ ΔG ■ Stability of viral capsids *For more details, please refer to the PDF document or feel free to contact us.

  • Other protein analysis

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High-precision quantification tool for proteins and nucleic acids 'LUNATIC'

No complicated workflows needed! Only 2μL of sample volume required. Measure up to 96 samples in just 5 minutes.

"Lunatic" is a product that allows for easy simultaneous quantification of proteins, DNA, and RNA. The required sample volume is only 2μL, and up to 96 samples can be measured in 5 minutes. High-concentration samples can also be measured directly without dilution. 【Features】 ■ Measure 2μL, up to 96 samples in 5 minutes ■ Dynamic range coverage from 0.02 to 200 mg/mL* *for mAb ■ Outstanding accuracy and precision ■ Automation is also possible *For more details, please refer to the PDF document or feel free to contact us.

  • Analytical Equipment
  • Other protein analysis
  • Other measurement and measuring equipment

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Bench-top fully automatic buffer exchange concentration device "UNAGI"

Up to 8 samples can be processed simultaneously! Automatic and hassle-free buffer exchange and concentration that used to be complicated!

Buffer exchange and concentration must be performed as a sample preprocessing step. This is a labor-intensive task that takes a long time, requiring your presence throughout the process. "UNAGI" is a fully hands-free benchtop buffer exchange solution designed to take over this tedious task. It can process up to 8 samples simultaneously. The software is very easy to operate, allowing you to be anywhere during the work, eliminating the need to stay in the laboratory the entire time. 【Features】 ■ Simultaneous processing of up to 8 samples ■ Efficient solvent removal prevents sample adsorption, achieving over 96% recovery rate ■ Built-in recipes for UF/DF buffer exchange ■ User-friendly software ■ Concentrates up to 8 diluted samples from 48mL to 8mL in one go *For more details, please refer to the PDF document or feel free to contact us.

  • Other Protein Research Software
  • DNA analysis

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Bench-top fully automatic buffer exchange concentration device "UNAGI"

[Video Available] Are you spending a lot of time and effort on buffer exchange and concentration work? You can streamline the sample preprocessing steps with this device.

Buffer exchange and concentration must be performed as a pre-treatment of the sample, which is a time-consuming task. This process takes a long time, and you have to be present the entire time. "UNAGI" is a fully hands-free benchtop buffer exchange solution designed to perform this tedious task for you. You can be anywhere during the process, eliminating the need to stay in the laboratory the whole time. 【Features】 ■ Simultaneous processing of up to 8 samples ■ Efficient solvent removal to prevent sample adsorption, achieving over 96% recovery rate ■ Built-in recipes for UF/DF buffer exchange ■ User-friendly software ■ Concentration of up to 8 diluted samples from 48mL to 8mL in one go *For more details, please refer to the PDF document or feel free to contact us.

  • Other Protein Research Software
  • Other filtration and separation equipment

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High-throughput fully automatic buffer exchange concentration device "BIGTUNA"

Significantly reduces the effort and time spent on buffer exchange and concentration.

"BIGTUNA" is a high-throughput fully automated buffer exchange and concentration device that can automate buffer exchange with a setup time of just 30 minutes, accommodating a wide range of sample numbers and volumes. We offer two types of plate-based filters that can simultaneously exchange and concentrate 24 or 96 samples. With easy setup, you can have better control over your experiments and significantly reduce manual labor time. You can step away from the tedious task of buffer exchange and use the extra time for what you truly want to do. 【Features】 ■ Free yourself from manual buffer exchange ■ Accommodates a wide range of sample numbers and volumes ■ Processes at an optimal buffer exchange rate ■ Automatically concentrates from 48mL to 8mL ■ Easy condition settings *For more details, please refer to the PDF document or feel free to contact us.

  • Other concentrating equipment

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Lipid nanoparticle automatic synthesis system Sunshine

Efficient mass production of LNPs - Supporting everything from small-scale condition testing to scale-up.

Once we succeed in finding the optimal formulation conditions for sunscreen, let's use Sunshine to adjust the size of the LNP. Furthermore, we will optimize the protocols and processes for scaling up. We will find the ideal flow rate and explore different mixing options. Next, we will adjust these to the appropriate dilution factor that can keep them stable. Once everything is in place, Sunshine will transition to continuous mode, allowing us to produce several dozen liters in a day. In other words, we will achieve process development and scaling up on a single platform. Many researchers have likely been looking forward to the birth of such a groundbreaking system. • 10 experiments in 15 minutes • Fraction & total flow • From 1 mL to continuous flow • Flow rate 0.1 to 30 mL/min • Reusable microfluidic chips • Possible transition of protocols from sunscreen

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Automatic Synthesis and Screening System for Lipid Nanoparticles Sunscreen

Accelerating formulation optimization for vaccine and pharmaceutical development.

To create the optimal LNP, it takes a tremendous amount of time and effort to examine and pursue formulation conditions. LNPs are nanoparticles composed of multiple lipids. Therefore, it is necessary to find the optimal conditions such as the mixing ratios, the ratio of lipids to payload, and the flow rates during mixing. Furthermore, we must also consider throughput issues. Sunscreen can produce up to 96 types of small LNPs within six hours, thus solving the previous throughput problems. This means that it is possible to explore a greater number of formulation condition investigations in a single day. • Fully automated execution of up to 96 types of condition investigations within six hours • 200 μL to 2 mL per experiment • Flow rate of 0.1 to 30 mL/min • Reusable microfluidic chips • Seamless scale-up through process and protocol optimization

  • Other Physics and Chemistry Equipment

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[Webinar] The Bright Future Brought by the Sun Series to LNP Formulations

Introducing the details of the newly launched LNP production and screening device.

Researchers of lipid nanoparticles (LNPs) spend a tremendous amount of time on screening, optimization, and scaling up experiments to achieve optimal performance, spot-on targeting, and controlled release of active pharmaceutical ingredients (APIs). Factors such as solubility, pH stability, payload release, and encapsulation all depend on particle size, shape, and structure. In other words, to obtain the right formulation, it is necessary to explore a vast number of formulation parameters and process parameters one by one, and even if a perfect formulation is found, scaling up usually means switching equipment and re-optimizing settings. In this webinar, we will introduce a platform, Sunny Suite, that can reduce the time spent on these LNP formulations. ■ Date and Time: February 26 (Monday) 14:00~ ■ Speaker: Yuji Senoo, Field Application Scientist, Unchained Labs, Inc. ■ Register here: https://unchainedlabs.zoom.us/webinar/register/3217065146675/WN_U1o3xQoZRAKHN-A-7b1yqg

  • Other protein analysis

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Acceleration of Gene Therapy Development through Evaluation of Lentivirus Characteristics: 'Replicon'

It enables the monitoring of potency and purity throughout the entire workflow of lentivirus research and development, accelerating gene therapy development.

"Leprechaun" is a system that analyzes whether lentivirus particles are of the correct size and structure, and can measure viral titer. It allows for the determination of the titer of lentivirus present in a sample without being misled by confusing noise (such as incomplete viruses or contamination). Not only can it measure information that was previously only obtainable separately through conventional methods like ELISA, qPCR, and transduction assays, but it also enables structural analysis that those methods could not provide, all on a single platform. Capabilities: ■ Lentivirus titer ■ Lentivirus structure ■ Exosome concentration ■ Analysis of contamination (impurities such as extracellular vesicles) Features: ■ No sample purification required ■ Physical structural analysis possible ■ Distinction between virus integrity and impurities ■ Up to 16 samples can be measured at once *For more details, please refer to the PDF document or feel free to contact us.

  • Other measurement and measuring equipment

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Ultra-fast viscometer "Honeybun"

You can measure 10 samples at once! There's no need to clean expensive chips that are prone to clogging!

"Honeybun" is a high-speed viscometer that can output data almost simultaneously with processing. Regardless of whether the number of samples is 1 or 10, it uses a few microliters of each sample through a microchannel and reads viscosities in the range of 0.5-150 cP within a few minutes. No pre-treatment or cleanup of samples is necessary. 【Features】 ■ Can measure up to 10 samples at once ■ Required sample volume: 35μL (can measure from 15μL; see application notes) ■ Measurement completed in under 1 minute (for viscosities below 10 cP) ■ Measurement range: 0.5-150 cP ■ No cleaning required and maintenance-free *For more details, please refer to the PDF document or feel free to contact us.

  • Other bio-related products

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Bench-top fully automatic buffer exchange concentration device "UNAGI"

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Protein quantification tool "Stunner"

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Measurement of adenovirus titer and characterization using Stunner.

Measurement of adenovirus titer and characterization using Stunner.

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Lipid Nanoparticle (LNP) Research Application Note vol.2

Lipid Nanoparticle (LNP) Research Application Note vol.2

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Lipid Nanoparticle (LNP) Research Application Note vol.1

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DNA leakage before the collapse of CapSID: Uncle's AAV thermal stability

DNA leakage before the collapse of CapSID: Uncle's AAV thermal stability

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Are you spending a lot of time and effort on buffer exchange and concentration work?

Are you spending a lot of time and effort on buffer exchange and concentration work?

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High-throughput fully automatic buffer exchange and concentration device 'BIG TUNA'

High-throughput fully automatic buffer exchange and concentration device 'BIG TUNA'

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Statistical Analysis Software JMP: Basics of Nonlinear Regression and Practical Application in JMP - Key Points for Business Utilization Explained.

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  • SEMINAR_EVENT

This is a webinar that explains the basic concepts of nonlinear regression and practical analytical methods using JMP. We will welcome Mr. Fukushima, who is in charge of biostatistics at Takumi Information Technology and has extensive experience in the pharmaceutical industry and knowledge of statistical analysis, as our instructor. Target Audience: - Those who want to learn about nonlinear regression and understand it from the basics. - Those involved in data analysis in fields such as pharmaceuticals and manufacturing, who are interested in utilizing nonlinear models. - Those interested in data analysis using JMP and want to apply it in practice. Program: - Part 1: Introduction to Data Visualization and Nonlinear Regression An overview of the basics of nonlinear regression using non-clinical trials in the pharmaceutical industry as a subject. - Part 2: Features of Nonlinear Regression in JMP and Examples of Its Use in Quality Control An explanation focusing on the functions and features of nonlinear regression in JMP. ▼ Details & Registration https://www.jmp.com/ja/events/live-webinars/non-series/2026/06-25-nlr

Jun 05, 2026

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[Seminar] Solar Panel Recycling Policies and Business Trends

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  • SEMINAR_EVENT

[Key Lecture Content] 1. Promotion of Solar Panel Recycling Yuta Okazaki, Director, System Planning Office, General Affairs Division, Environmental Restoration and Resource Recycling Bureau, Ministry of the Environment 1. Previous efforts regarding the disposal and recycling of solar panels 2. Laws related to the promotion of resource recovery from solar cell waste 3. Q&A / Business card exchange 2. Expansion of Solar Power Generation and Formation of a Positive Cycle for Panel Resource Recycling Akihou Kawai, Analyst, Materials Team, Industrial Research Department, Mizuho Bank 1. Policy trends surrounding solar power generation 2. Trends in the solar power generation industry 3. Resource recycling related to solar power generation and panels 4. Examples of initiatives by businesses towards resource recycling - Towards glass recycling 5. Examples of initiatives by businesses towards resource recycling - Towards efficient collection 6. Examples of initiatives by businesses towards resource recycling - Guarantees and insurance for solar power generation equipment and related trends 7. Awareness of issues and directions for problem-solving regarding resource recycling of solar panels 8. Q&A / Business card exchange

Jun 05, 2026

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[Seminar] Latest Trends in the Submarine Cable Industry

  • NEW
  • SEMINAR_EVENT

[Key Lecture Content] 1. New Trends in the Submarine Cable Market: Current Status and Outlook Mr. Takuya Makiyama, Senior Researcher, Mobility and Communication Policy Headquarters, Mitsubishi Research Institute 1. Why are submarine cables attracting attention now? 2. Overview of the submarine cable market 3. Major players and changes in industry structure 4. Future outlook and expectations 5. Q&A / Business card exchange 2. Submarine Cables Supporting International Communication and KCS's Initiatives Mr. Tomonori Shinto, Executive Officer and Senior Managing Director, Technical Operations Headquarters, KDDI Cable Ship Co., Ltd. 1. Business introduction 2. Overview of submarine cables 3. Various operations related to submarine cables 4. Current status and challenges of the submarine cable industry 5. Q&A / Business card exchange

Jun 05, 2026

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[Seminar] Revitalization and Growth Strategies of the Defense Industry in Japan, Europe, and the United States

  • NEW
  • SEMINAR_EVENT

[Speaker] Ayaka Hiraki, Fellow at Deloitte Tohmatsu Research Institute, General Incorporated Association [Key Lecture Content] Due to high tariff measures and withdrawal from international organizations by the second Trump administration in the United States, military operations in Venezuela, and attacks on Iran, the world is indeed "Under Destruction." As the economy and cutting-edge technologies become intertwined with security, this lecture will analyze the trends in the defense industries of Japan, Europe, and the United States from three perspectives: "modular security," "total defense," and "the rise of artificial intelligence (AI)," while examining the potential and challenges of Japan's defense industry. [Lecture Topics] 1. Changes in Japan's security environment 2. Three points to consider for future security systems (1) Modular security architecture (2) Total defense (3) AI 3. Initiatives in Japan, Europe, and the United States (1) Europe: European defense industry strategy and strategic autonomy (2) United States: National security strategy under the Trump administration (2025 NSS) and defense innovation (3) Japan: Key points of the FY2026 budget and trends towards the revision of three strategic documents 4. Future outlook for the defense industry - possibilities and challenges regarding participation 5. Q&A

Jun 05, 2026

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[Seminar] System and Practice Related to Solar Power Generation Business

  • NEW
  • SEMINAR_EVENT

[Speaker] Anderson Mori & Tomotsune Law Office Foreign Law Joint Enterprise Partner Attorney Eiji Kobayashi [Lecture Topics] 1. FIT/FIP System in Solar Power Generation Business (1) Overview of FIT/FIP System Based on Renewable Energy Law (2) Background of Amendments to Renewable Energy Law Related to Solar Power Generation Business (3) Key Practical Points in Current Renewable Energy Law 2. Amendments and Regulations Related to Solar Power Generation Business (1) Forest Law (2) Electricity Business Law (3) Environmental Impact Assessment (4) Landscape Law (5) Others 3. Q&A Session

Jun 05, 2026

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