Flow Imaging Particle Image Analysis System - FlowCam Series
FlowCam Series
A flow imaging microscope capable of particle size distribution and particle image analysis in solution. It is used for detecting impurities in biopharmaceuticals.
Features - Measurement possible with a small sample volume (100 μL and above) - Measurable particle size: 0.3 μm to 600 μm - High-resolution image analysis through threshold optimization - Equipped with autofocus function - Capable of saving raw image (video) files - No sheath fluid required - Easy replacement of flow cell and simple cleaning - Lens interchangeable (2X, 4X, 10X, 20X) - Compatible with dedicated auto-sampler - Compliant with 21 CFR Part 11
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basic information
The FlowCam series is a particle image analysis system that combines digital imaging technology with optical microscopy technology. It captures high-speed images of microparticles in solution through an optical microscope and performs automatic analysis in real-time. It can simultaneously obtain information on particle size distribution and particle images. In addition to particle size and concentration, the ability to evaluate particle shape through image analysis allows for detailed analysis of samples that cannot be understood through simple particle size distribution.
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Applications/Examples of results
Measurement targets: biopharmaceuticals, protein aggregates, microcapsules, cells, ink toners, abrasive particles, resin raw materials, microfibers, cosmetic ingredients, etc.
Detailed information
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Evaluating insoluble particles and subvisible particles (SVP) contained in biopharmaceuticals is extremely important for ensuring the quality of pharmaceuticals. FlowCam can detect SVP contained in biopharmaceuticals, such as protein aggregates, bubbles, and silicone oil droplets, and allows for evaluation through imaging.
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Optimization of Particle Detection Conditions (Threshold) In FlowCam, it is possible to optimize the threshold for particle recognition. Since measurement videos can be completely saved, it is easy to conduct threshold condition studies using the same video. This is a useful feature for more accurately capturing fragmented particle recognition.
Line up（5）
| Model number | overview |
|---|---|
| FlowCam 8000 Series | Minimum particle size: 2μm Maximum particle size: 1 mm |
| FlowCam 5000 | Minimum particle size: 2 μm Maximum particle size: 1 mm* depending on the lens. A model that is easy to introduce with limited functions. The software is common with the 8000 series. |
| FlowCam nano | Minimum particle size: 300 nm Maximum particle size: 2 μm |
| FlowCam Macro | Minimum particle size: 50 μm Maximum particle size: 5000 μm |
| FlowCam LO | Minimum particle size: 2 μm Maximum particle size: 70 µm Simultaneous measurement using Flow Imaging Method (FIM) and Light Obscuration Method (LO) |
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Company information
DKSH is a member of the Swiss global company "DKSH Group." It provides comprehensive services and solutions across the entire value chain, combining procurement, marketing, sales, distribution, and after-sales service, through its three business divisions: consumer goods, production materials, and technology, with a long-term perspective.
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