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  6. Safety testing of pharmaceuticals: Measurement of concentration in biological samples.

Safety testing of pharmaceuticals: Measurement of concentration in biological samples.

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last updated:Mar 10, 2022

イナリサーチ
イナリサーチ
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For TK exams, turn to Inari Research with its abundant experience and track record!

At Inari Research, we measure and analyze the concentrations of test substances and metabolites in biological samples obtained through safety tests (TK) and pharmacokinetic tests (PK). GLP compliance is possible. We also have extensive analysis experience in multi-site studies. We conduct ISR (Incurred Sample Reanalysis) in accordance with guidelines. If you provide kits or antibodies, we can also perform measurements using immunoassay methods. 【Concentration Measurement in Biological Samples】 ■ Targets: Measurement of test substances and their metabolites in biological samples such as blood, urine, feces, and tissue homogenates. ■ Methods: Protein precipitation, solid-phase extraction, liquid-liquid extraction, etc. ■ Measurement Conditions: LC-MS/MS and HPLC, etc. *For more details, please refer to the PDF document or feel free to contact us.

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血液サンプル-5(サイズ縮小版).jpg

Safety testing of pharmaceuticals: Measurement of concentration in biological samples.

血液サンプル-5(サイズ縮小版).jpg
血液サンプル-5(サイズ縮小版).jpg
  • Related Link - http://www.ina-research.co.jp/service/

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Inari Research supports toxicity testing from the screening stage until entering clinical trials (clinical studies). We conduct a wide range of tests based on our extensive testing experience and accumulated background data using standard test subjects such as mice, rats, rabbits, dogs, and of course, monkeys. The tests are conducted in a GLP-compliant facility that has obtained certification from AAALAC International (Association for Assessment and Accreditation of Laboratory Animal Care International). A series of non-clinical test sets, including genotoxicity tests and safety pharmacology tests necessary to enter clinical trials (Phase I), can be completed with the final report prepared within six months. *For more details, please refer to the PDF materials or feel free to contact us.

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Contract Testing Service "Pharmaceutical Safety Testing"

Contract Testing Service "Pharmaceutical Safety Testing"

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イナリサーチ

イナリサーチ

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Our company is located in the nature-rich city of Ina, Nagano Prefecture, surrounded by two Alps, and has been serving our customers as a non-clinical trial contract research organization (CRO) for 50 years. Since 2022, we have become a member of the Shin Nippon Science Group, expanding and enhancing our contract testing items and analyses, and we can quickly respond to the procurement of various testing materials (such as animals). Non-Clinical Trial Business We accept safety and efficacy testing for pharmaceuticals, chemicals, pesticides, food, medical devices, and more. We conduct in vivo tests using small animals, rabbits, dogs, and monkeys, as well as in vitro tests using bacteria and cells, and various alternative method tests. Additionally, we specialize in the creation of SEND data required for FDA applications for new drugs, and we also undertake work related to SEND conversion and QC for data creation and conversion only. Our facility was the first in Japan to obtain full accreditation from AAALAC International (the Association for Assessment and Accreditation of Laboratory Animal Care International), and we are committed to international standards of animal welfare. We also propose tests necessary for various applications and registrations in compliance with regulations in different countries and regions.

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