Book: Continuous Production of Fine Chemicals and Pharmaceuticals (No. 2272)

[Available for preview] - Flow synthesis / Separation and purification / Powder process / Monitoring -

Book Title: Fine Chemicals, Continuous Production Processes for Pharmaceuticals ---------------------------- ★ Case studies of proof-of-concept experiments at lab/pilot scale and implementation in commercial facilities revealed by leading companies! ★ Development of requirements and management strategies for ICH Q13, and how to respond! ---------------------------- ■ Key Points of This Book Continuous Mixing and Reaction Processes - Design of flow microreactors, scale-up, and measures against flow path blockage - Automation of reaction condition exploration using Bayesian optimization - Case studies on catalyst and process development for continuous production - Continuous culture for biopharmaceutical production Continuous Separation Processes - Selection of operating conditions for continuous crystallization, control of particle size/shape, and productivity improvement - Design of continuous distillation columns and automated exploration of efficient operating conditions - Continuous processing of membrane filtration, rotary filtration, and centrifugation, along with case studies - Continuous separation of proteins, chiral compounds, and viruses for pharmaceutical production Continuous Powder Processes - Continuous granulation, configuration of direct compression systems, and setting of operating conditions

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