Multi-Angle Light Scattering (MALS) Detector DAWN Series
Wyatt Technology・ DAWN
High-precision measurement of absolute molecular weight in the range of hundreds to hundreds of millions Da for the characterization of polymers, proteins, and nanoparticles!
The DAWN series measures the molecular weight and size of macromolecules such as proteins with high precision, using multi-angle light scattering (MALS) without the need for calibration curves created from standard substances. It can be connected to HPLC and UPLC, enabling a wide range of applications. 【Features】 - DAWN (18-angle detector) offers high sensitivity and wide-range measurement. - A diverse lineup including DAWN8 (8-angle detector), miniDAWN (3-angle detector), microDAWN (UPLC-compatible model), and UltraDAWN (process-compatible model). - Automated cell cleaning with built-in ultrasonic cleaner COMET. - Equipped with a dynamic light scattering (DLS) module, allowing measurements from a radius of 0.5 nm (optional). - Real-time display of system status, with troubleshooting guidance functionality. By clicking [Send], you agree that the information provided on this site will be used and processed by Waters in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy
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basic information
There are three types of detectors for HPLC. We will make suggestions based on your application, so please feel free to contact us. DAWN (18 angles) measurement range: 1) Molecular weight (Da): 200 to 1G (proteins) 2) Molecular size (radius): 10 to 500 nm DAWN8 (8 angles) measurement range: 1) Molecular weight (Da): 200 to 100M (proteins) 2) Molecular size (radius): 10 to 300 nm miniDAWN (3 angles) measurement range: 1) Molecular weight (Da): 200 to 10M (proteins) 2) Molecular size (radius): 10 to 50 nm
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Delivery Time
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Applications/Examples of results
We support various applications such as peptides, proteins, synthetic polymers, natural polymers, vesicles, emulsions, and nanoparticles.
Line up（2）
| Model number | overview |
|---|---|
| micro DAWN (for UHPLC) | This is a 3-angle MALS detector designed for UPLC and downsized SEC/GPC applications, featuring a low dispersion design. The flow cell capacity has been minimized to allow light scattering measurements without compromising the high separation of UPLC and APC systems. |
| ultraDAWN (for process analysis) | By obtaining real-time results for molecular weight, size, particle concentration, and more, it accelerates process development and scale-up. It allows for direct monitoring of critical quality attributes (CQA), providing rapid feedback on product and process quality. |
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Company information
Waters Corporation, headquartered in Milford, Massachusetts, USA, has played a pioneering role as a specialized manufacturer of liquid chromatography since its establishment in 1958. Actively engaged in the development of new products and technologies, it has grown into an international group company that supplies not only high-performance liquid chromatography but also mass spectrometers (MS) and thermal analysis instruments. Waters Japan started operations in 1973 (Showa 48) as the Japanese base of Waters Corporation. Inheriting the corporate ethos of the U.S. headquarters, we have made "Customer Success" our mission and continue to provide innovative technologies and lab solutions.
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