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  6. [P-725.xCDE2 for Biotechnology]

[P-725.xCDE2 for Biotechnology]

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P-725.xCDE2

last updated:Feb 17, 2026

PI Japan
PI Japan
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Sub-nanometer resolution, Z-direction maximum stroke of 800 µm, equipped with a flexure mechanism focus scanner.

In the field of biotechnology, precise focus control is essential for high-resolution observation of the fine structures of cells and tissues in microscopic imaging applications. This is particularly true for 3D imaging techniques such as confocal microscopy and multiphoton microscopy, where high resolution and fast responsiveness along the Z-axis (focus direction) directly impact observation accuracy. The P-725.xCDE2 PIFOC Focus Scanner employs a flexure guide mechanism with PICMA piezo actuators and capacitive sensors to achieve precise focus control with sub-nanometer resolution. It also supports a maximum stroke of 800 µm, enabling fast and high-precision scanning over a wide range in the depth direction. These characteristics help reduce observation time while minimizing focus position shifts, ultimately contributing to improved reliability and efficiency of experiments. 【Application Scenes】 - Confocal microscopy - Multiphoton microscopy - 3D imaging - Live cell imaging - High-throughput microscopy screening 【Benefits of Implementation】 - High-precision Z-direction focus control - Expanded range of focus stroke - Improved observation efficiency through fast scanning - Stable imaging quality

    Piezoelectric DevicesActuatorOther machine elements
csm_P-725.4CDE2__01041_Leitbild.tif_preview300_2c6e53d00a.jpg

[P-725.xCDE2 for Biotechnology]

csm_P-725.4CDE2__01041_Leitbild.tif_preview300_2c6e53d00a.jpg
csm_P-725.4CDE2__01041_Leitbild.tif_preview300_2c6e53d00a.jpg P-725_2.jpg
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basic information

【Features】 - Stroke: 100µm, 400µm, 800µm - Built-in capacitive sensor - Optimal for high-dynamics operation due to high rigidity - Flexibility of cables - Wide range of installation methods 【Our Strengths】 Based on over 50 years of experience at our headquarters in Germany and 30 years of experience with our Japanese subsidiary, we provide the best positioning solutions tailored to our customers' needs. We offer a wide product lineup, including piezo stages, and can propose integrated systems customized for our customers' applications.

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Applications/Examples of results

- Various types of microscopes (confocal, light sheet, super-resolution, two-photon, etc.) - 3D imaging - Screening - Interferometric measurement devices - High-precision measurement - Autofocus system - Biotechnology - Semiconductor inspection, etc.

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Model number overview
P-725.1CDE2 PIFOC piezo nanofocusing system for long travel ranges and fast step-and-settle, 100 µm, capacitive sensors, D-sub connectors
P-725.4CDE2 PIFOC piezo nanofocusing system for long travel ranges and fast step-and-settle, 400 µm, capacitive sensors, D-sub connectors
P-725.8CDE2 PIFOC piezo nanofocusing system for long travel ranges and fast step-and-settle, 800 µm, capacitive sensors, D-sub connectors

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P-725.xCDE2 Long-distance movement PIFOC objective lens piezo scanner

P-725.xCDE2 Long-distance movement PIFOC objective lens piezo scanner

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PI

PI Japan

Electronic Components and Semiconductors

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The German headquarters, with over 50 years of experience and 30 years as a Japanese corporation, presents new solutions from PI, a company specializing in precision positioning products. We offer the world's number one piezo stages and actuators, as well as hexapod positioning products. Additionally, we are enhancing our lineup of linear motor-driven products and high-precision air bearing stages. In positioning, attention to the foundation is also crucial, and we provide granite bases, enabling us to propose composite systems as well. Please take a look at our diverse lineup that provides cutting-edge technology to production sites around the world, advanced equipment, and various fields of cutting-edge research.

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