Tohoku University Technology: Gene Introduction Device and Gene Introduction Method: T13-033
Achieving minimally invasive gene introduction with overwhelmingly high cell survival rates and introduction efficiency using an atmospheric pressure plasma device!
Gene introduction technology is actively researched in the production of iPS cells and gene therapy, with various methods proposed. Traditional representative techniques include electroporation, viral methods, and liposome introduction methods. However, each has challenges such as low survival rates, side effects, and limitations on the genes that can be introduced. The present invention develops a method for high-efficiency, low-invasive gene introduction by irradiating cells with "atmospheric pressure plasma," which activates the cell membrane through chemical stimulation from short-lived reactive species in the plasma and electrical stimulation from an electric field locally formed on the cell surface, allowing genes to be taken up into the cells.
- Company:Tohoku Techno Arch Co., Ltd.
- Price:Other