一般財団法人材料科学技術振興財団　MST List of Products and Services

When describing cleaning methods in brochures for medical devices, it is necessary to confirm the validity of those cleaning methods. In this case, as a verification experiment for the wiping method of medical devices, we applied bovine serum albumin (BSA), a blood model drug, to sheets of acetyl cellulose (TAC), SUS-made scalpels, and glass, and evaluated the residual components before and after wiping using TOF-SIMS. As a result, it was found that ethanol is more suitable than water for wiping BSA, and that the wiping effectiveness varies depending on the substrate. Measurement method: TOF-SIMS Product field: Medical devices and pharmaceuticals Analysis purpose: Composition evaluation, identification, composition distribution evaluation, failure analysis, defect analysis For more details, please download the materials or contact us.

Medical injection needles reduce puncture resistance and lessen the physical burden on patients by coating the surface of the metal tube with silicone. To maintain the performance of the needle, it is important that the entire surface is covered with a coating film. This report introduces a case where imaging analysis of the opening at the tip of the injection needle was conducted using TOF-SIMS to evaluate whether the coating film was applied. Since TOF-SIMS detects information from the very surface, it can assess the condition of the coating film without detecting the underlying elements.

Dental implants are artificial devices that are embedded in the jawbone when teeth are lost due to cavities or periodontal disease. Since they are implanted in the body, evaluating the condition of the surface area that comes into direct contact with biological tissue is important. TOF-SIMS not only provides qualitative analysis of the top surface but also excels in depth resolution at the top surface, allowing for highly sensitive evaluation of the condition in the depth direction. This case summarizes the results of evaluating the state of titanium in dental implants in the depth direction.

Dental implants are artificial devices that are embedded in the jawbone when teeth are lost due to cavities or periodontal disease. The materials used for implants are often titanium or titanium alloys, and various coatings are applied to the surface to promote the bonding between the implant and the bone. Since implants are embedded in living organisms, the safety assessment of the surface area that comes into direct contact with biological tissues is crucial. XPS can evaluate the composition and bonding state of the very surface (approximately 5 nm). This document presents examples of evaluations conducted using XPS.

Dental implants are artificial devices that are embedded in the jawbone when teeth are lost due to cavities or periodontal disease. Since implants are directly embedded in the body, evaluating their safety is crucial. This document presents a case where the quantification of impurity elements was conducted using Dynamic-SIMS. The analysis results revealed that, in addition to the main component Ti, O and Fe were also present. Dynamic-SIMS can evaluate the elemental distribution in a depth of several micrometers at the order of ppm to ppb.

There are materials in polymers that change shape depending on the environment. To observe the original shape of the sample, measurements in real environmental conditions are necessary. This document presents a case study that visualizes the surface shape of soft contact lenses in saline solution. By measuring under conditions close to the actual environment, it is possible to evaluate while maintaining the original shape of the sample.