Technical Information Magazine 202303-01 Comprehensive Analysis of Biomolecular Interactions
This paper presents a comprehensive analysis of interactions using multiple methods, including surface plasmon resonance and isothermal titration calorimetry.
The technical information magazine The TRC News provides the latest information on analytical techniques that are useful for research and development, solving production troubles, and quality control. [Abstract] Molecular interaction analysis is an indispensable method in the study of life phenomena and the development of therapeutic drugs. The information on interactions obtained by different methods varies; for instance, surface plasmon resonance provides kinetic parameters of interactions, while isothermal titration calorimetry can acquire thermodynamic parameters of interactions. This paper introduces comprehensive analysis cases of interactions using multiple methods through multifaceted analysis. [Table of Contents] 1. Introduction 2. Surface Plasmon Resonance / Isothermal Titration Calorimetry 3. Analysis of the Interaction between STING and cGAMP 4. Conclusion
Inquire About This Product
basic information
Technical Information Magazine The TRC News "Comprehensive Analysis of Biomolecular Interactions" 【Abstract】 Molecular interaction analysis is one of the indispensable methods in the study of life phenomena and the development of therapeutic drugs. The information obtained from interactions varies depending on the method used; for example, surface plasmon resonance provides kinetic parameters of interactions, while isothermal titration calorimetry can acquire thermodynamic parameters. This paper introduces case studies of comprehensive analysis of interactions using multiple methods for multifaceted analysis. 【Table of Contents】 1. Introduction 2. Surface Plasmon Resonance / Isothermal Titration Calorimetry 3. Analysis of the Interaction between STING and cGAMP 4. Conclusion 【Figures and Tables】 Figures 1 to 9, Table 1 Kinetics analysis results of STING and cGAMP by SRP Thermodynamic analysis results of STING (WT) and cGAMP by SPR Thermodynamic analysis results of STING (R232H) and cGAMP by ITC Comparison of thermodynamic parameters Changes in binding free energy for each STING and cGAMP interaction (differences by amino acid residue) X-ray crystal structures of each STING and cGAMP complex
Price information
2,200 yen (including tax)
Price range
P1
Delivery Time
P1
※Web application, PayPal payment
Applications/Examples of results
Please see https://www.toray-research.co.jp/service/trcnews/.
Company information
At Toray Research Center, Inc., we provide technical support through analytical techniques and physical property analysis to address various challenges in research and development as well as production fields via contract analysis. Based on our long-standing achievements and extensive experience in analysis and physical property evaluation, we continue to strive to meet the advanced and diverse needs of our customers.
![[AICFD] Cooling Analysis of Battery Packs for New Energy Vehicles](https://image.mono.ipros.com/public/product/image/3a5/2001523984/IPROS14260339215625759081.png?w=280&h=280)
![[Case Study] The IT department leads the digitalization of operations.](https://image.mono.ipros.com/public/product/image/ec9/2000612311/IPROS98068577639981389025.png?w=280&h=280)
![On-site Improvement and Work Analysis Helpful Materials [Nao Sasaki's Improvement Column]](https://image.mono.ipros.com/public/product/image/720/2000613979/IPROS10933623742376703553.png?w=280&h=280)
![[Book] Utilizing AI for Exploring New Business Themes (No. 2374)](https://image.mono.ipros.com/public/product/image/342077/IPROS6452675495331564511.gif?w=280&h=280)