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  3. メルク株式会社ライフサイエンス(シグマ アルドリッチ ジャパン合同会社)
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メルク株式会社ライフサイエンス(シグマ アルドリッチ ジャパン合同会社)

number of employees700
addressTokyo/Minato-ku/1-3-1 Azabudai, Azabudai Hills, Mori JP Tower, 26th Floor
phone03-4316-8000
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last updated:Dec 16, 2024
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メルク株式会社ライフサイエンス(シグマ アルドリッチ ジャパン合同会社) List of Products and Services

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Ultra-pure water and pure water equipment (for testing and research) Ultra-pure water and pure water equipment (for testing and research)
Application-specific ultrapure water and pure water systems Application-specific ultrapure water and pure water systems
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Invitation to Merck Life Science Webinar <Ultrapure Water and Pure Water Edition>

Proper water quality management can contribute to improvements in the stability and efficiency of tests, among other benefits!

Merck KGaA, Life Science will hold webinars in 2025 that incorporate new content. In the webinar "Ultra-Pure Water Production Equipment for PFAS Analysis," we will introduce the characteristics of PFAS and the role of ultra-pure water as blank water in PFAS analysis. In "Pure Water and Its Management for Weather Resistance Testing and Environmental Testing," we will discuss the impact of pure water quality in weather resistance testing. By participating in this webinar, you will gain specific knowledge about the management of testing water, improve the reliability of test results, and strengthen the quality assurance process for pharmaceuticals, among many other benefits. We encourage you to join us. 【Webinar Overview】 ■ Ultra-Pure Water Production Equipment for PFAS Analysis ・Date: August 27, 2025 (Wednesday) ・Time: 15:00 - 16:00 ■ Pure Water and Its Management for Weather Resistance Testing and Environmental Testing ・Date: October 29, 2025 (Wednesday) ・Time: 15:00 - 16:00 *For more details, please download the PDF or feel free to contact us.

  • Technical Seminar

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[June 18] Free Webinar "Production and Management of Water for Pharmaceutical Testing"

An explanation of the impact of the quality of test water, which is essential in pharmaceutical testing, on test results!

Our company will hold a webinar on the production and management of pharmaceutical testing water, focusing on ultra-pure water and pure water. We will provide specialized knowledge on the standards and purification methods for testing water based on the Japanese Pharmacopoeia, as well as management techniques. Participants will deepen their understanding of specific water quality standards and their impacts, gaining practical knowledge. In particular, we will clearly demonstrate how the quality of testing water contributes to the final quality assurance of pharmaceuticals and provide information that can be useful for your own quality management. [Webinar Overview] ■ Date: June 18, 2025 (Wednesday) ■ Time: 15:00 - 16:00 ■ Registration Deadline: 14:00 on the day of the event *For more details, please check the link below.

  • Seminar

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2025 Fiscal Year Budget Application Selection Guide: Equipment for Cell and Protein Research

High-sensitivity immunoassay systems and automatic two-dimensional electrophoresis devices! Introducing a diverse lineup.

This document is a selection guide for budget applications for cell and protein research equipment for the fiscal year 2025. It features a variety of products, including the "xMAP INTELLIFLEX System," which can simultaneously measure up to 500 types of proteins from small sample volumes, and the "SMCxPRO," which achieves biomarker quantification at the femtogram (fg/mL) level. The guide includes photos along with features and system specifications, making it a useful reference when selecting products. We encourage you to take a look. [Contents (partial)] ■ xMAP INTELLIFLEX System ■ Luminex 200 System ■ FLEXMAP 3D System ■ SMCxPRO ■ Auto2D *For more details, please download the PDF or feel free to contact us.

  • Cell Counter
  • Other Protein Research
  • Other cell research

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Handheld Automatic Cell Counter 'Scepter 3.0'

Easily and accurately count cells! Large display for clear measurement results.

The "Scepter 3.0" is a compact handheld cell counter that employs the Coulter method, which is also used in flow cytometers. The time-consuming cell counting process can now be completed in less than 30 seconds, and the automation of cell counting not only reduces individual variability but also makes it easier to manage data and create reports utilizing the measurement data. It can measure cells with a minimum diameter of 3μm and a maximum concentration of 1,500,000 cells/mL. 【Features】 ■ High-precision measurement and analysis functions condensed into a pipette size ■ Accurate cell count measurement enabled by the Coulter method ■ Measurement completed in 30 seconds from cell suspension, no staining required ■ Easy maintenance with disposable tips ■ USB charging station that can be easily installed next to a clean bench *For more details, please download the PDF or feel free to contact us.

  • Cell Counter

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Millicell DCI Digital Cell Imager

Quickly access past data to analyze cell growth trends! Achieve more stable cell culture.

The "Millicell DCI Digital Cell Imager" allows for easy measurement and evaluation of cell culture. It not only quickly and objectively measures common cell culture parameters such as confluency and cell count/morphology, but also saves time by measuring in-vessel, preserving valuable culture samples. Furthermore, by using a sophisticated web tool for data management, you can track and record cell culture data. 【Advanced Cell Monitoring (Partial)】 ■ Objective measurement of confluency and estimation of cell count ■ Accelerated analysis ■ Reduced user bias ■ Hemocytometer or in-vessel measurement ■ Culture of adherent cells, spheroids, and organoids *For more details, please download the PDF or feel free to contact us.

  • Imaging and image analysis equipment

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Digital Voltage Resistance Meter 'Millicell ERS 3.0'

Optimize transepithelial electrical resistance measurement! Intuitive touchscreen interface.

The "Millicell ERS 3.0" is a digital volt-ohmmeter that enhances intuitive and user-friendly features. By using a standalone measurement probe, it achieves more stable measurements. Real-time resistance and voltage data measurements allow for tracking of results. Additionally, using a cloud-based application simplifies analysis between wells and experiments, enabling low noise, excellent resolution, and high precision for consistent measurements. 【Features】 ■ Intuitive touchscreen interface ■ Data logging on the device and reduced background noise ■ Output results via Ethernet or USB drive, or upload to the cloud (optional) ■ Powered by cord for bench or tissue culture hood use, or battery pack *For more details, please download the PDF or feel free to contact us.

  • Insulation Tester

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A must-see for those considering PFAS analysis! Free webinar by Merck.

Learn with Merck's total solution! A must-see for those considering PFAS analysis.

We will hold a webinar titled "Thorough Explanation of the Workflow for PFAS Analysis and Essential Techniques to Keep in Mind with Merck's Total Solution" on Wednesday, May 14, 2025. In this webinar, we will introduce various applications based on our expertise, including the workflow for PFAS analysis, ultrapure water, sample preparation, and analytical columns. Participants will gain the foundational knowledge necessary for conducting PFAS analysis and will be able to meet various customer needs based on insights from different applications. We sincerely look forward to your participation. 【Event Overview】 ■ Date and Time: Wednesday, May 14, 2025, 15:00 - 16:00 ■ Recommended for: - Those involved in PFAS analysis in water utilities, environmental analysis, clinical settings, food and beverage manufacturers, cosmetics, universities, and government agencies. - Those considering PFAS analysis in the future. *For more details, please refer to the related links or feel free to contact us.

  • Seminar
  • Distance learning/E-learning
  • Distance learning/E-learning

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ADLib System Monoclonal Antibody Production

Complete in vitro method! Affinity maturation to obtain antibodies with higher binding capacity.

The "ADLib System" is an antibody acquisition platform based on cell surface display, and it is a proprietary technology of Kaiom Biosciences, Inc. It features "speed" since it does not require animal immunization, and it creates "a unique antibody library that utilizes the functions inherent to cells" to generate antibody diversity. Additionally, it is also possible to perform "unique and simple affinity maturation." 【Features】 ■ Approximately 7 weeks until the sequence report of selected clones ■ Effective against difficult antigens such as antibodies that are less likely to induce immune responses, low molecular weight compounds, and immune tolerance ■ Improvement of affinity for antibodies obtained from sources other than this system, such as those derived from hybridomas, is also possible *For more details, please download the PDF or feel free to contact us.

  • Other cells
  • Other Analysis
  • Cell-related contract

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Merck Microscope Reagent Catalog 2023

A diverse lineup of products including staining solutions for organization, blood smears, and staining solutions for blood cell count determination.

This catalog introduces the reagents for microscopes that we handle. It includes various products such as staining solutions for cytology, staining solutions for bacteria and microorganisms, and staining solutions for fiber examination. In addition, we also provide information on dyes, chromogenic substrates, fluorescent dyes, and fixatives, so please take a moment to read through it. [Contents (excerpt)] ■ Regarding orders ■ CE mark and others ■ Staining solutions for tissues ■ Staining solutions for cytology ■ Staining solutions for blood enhancement and cell count ■ Staining solutions for bacteria and microorganisms * The information contained in this catalog is as of 2023. * For more details, please download the PDF or feel free to contact us.

  • Staining Reagents
  • reagent

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Multiplex assay for the detection of antibodies against antigen proteins.

Developed three types of MILLIPLEX assay kits for research use only (RUO)!

The SARS-CoV-2 coronavirus is the pathogen that causes COVID-19 in humans. Since it was first discovered in Wuhan, China, in December 2019, this disease has become a global pandemic. SARS-CoV-2 is one of the seven identified coronaviruses that infect humans and can cause severe diseases along with SARS-CoV and MERS-CoV. Other types of coronaviruses (229E, NL63, OC43, HKU1) exhibit cold-like symptoms. *For more detailed information, please refer to the attached PDF document. Feel free to contact us for further inquiries.*

  • Filter paper/filter

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Analysis Preprocessing Myrex Guide

The importance of pre-analysis treatment using Myrex LG/LH/LCR and filters is also included!

This guide features a comprehensive selection of high-quality syringe filters, Millex, that are useful for sample processing in equipment analysis. It includes a variety of products such as "Myrex GV/HV/SV" equipped with hydrophilic PVDF membrane Durapore, and "Myrex GP/HP" with an asymmetric structure hydrophilic polyethersulfone (PES) membrane. Additionally, we also introduce the new suction filtration filter unit "Millicup-Flex," so please take a moment to read through it. [Contents (excerpt)] ■ Myrex Selection Guide for Pre-analytical Processing ■ Myrex Chemical Compatibility Guide for Major Pre-analytical Processing ■ Myrex LG/LH/LCR ■ Myrex GV/HV/SV ■ Myrex GP/HP ■ Myrex GN/HN *For more details, please download the PDF or feel free to contact us.

  • Filter paper/filter

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Merck Filter Comprehensive Catalog

Merck Life Science provides total support for your research!

This catalog is the comprehensive catalog of Merck Filters. It includes "Research," which supports the development of life sciences fundamental research, "Lab Water," which becomes a lifelong partner, and "Biomonitoring," which provides total support for microbiological testing. It is a useful book, so please make use of it when selecting products. 【Contents】 ■ Sample Preparation ■ Ultrafiltration ■ Cell Culture ■ Biochemical Assays ■ Appendix ■ Index *For more details, please download the PDF or feel free to contact us.

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Milli-Q IQ 7005/10/15 Trace Element Analysis Type

Design for maintaining high-purity ultrapure water quality! Suitable for trace element analysis.

We would like to introduce our products, the ICP-MS (ultra-trace element analysis) and the completely mercury-free ultrapure water production system 'Milli-Q IQ 7005/10/15 and Milli-Q IQ 7000 ultra-trace element analysis type' that we handle. In addition to ultrapure water purification in the purification unit of this product, the Milli-Q IQ Element removes ultra-trace metals containing boron to the utmost limit. This reduces the background derived from water, allowing for stable results in ultra-trace element analysis. 【Features】 ■ Designed to match the ultra-trace element analysis workflow ■ Contamination prevention ■ Minimization of maintenance ■ Overwhelming ease of use ■ Easy operation with a touch screen *For more details, please download the PDF or feel free to contact us.

  • Pure water production equipment

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Spectroquant Prove plus

A multi-parameter water quality meter that is fast, easy to use, and accessible to anyone for water quality analysis in water, environment, food, beverages, and more!

Spectroquant Prove plus is a spectrophotometer developed for the chemical analysis of drinking water, wastewater, and process water, allowing anyone to perform stable water quality measurements quickly and easily. By scanning the LiveID barcode attached to the dedicated reagent kits (cell tests and reagent tests), the measurement methods and calibration curve information are read, enabling customers to automatically measure simply by inserting the cell into the device after sample preparation. Results are quickly quantified, and data can also be exported via USB and other means. The device is programmed with over 180 applications. Analysis can now be performed more quickly than ever, allowing for the storage of more data for reference, thereby improving operational efficiency. 【Features】 ■ Long-life lamp ■ Smart display ■ Custom measurements ■ Individual measurement ranges ■ Start measurement simply by insertion ■ Easy cleaning *For more details, please download the PDF or feel free to contact us.

  • Analytical Equipment and Devices

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TLC Explorer

Digitalize analysis! Compact and portable to function off-grid.

The "TLC Explorer" is a product that provides digitized solutions, enhancing the efficiency and accuracy of quantitative analysis for consistent and easily shareable data interpretation. With high-resolution digital imaging, detailed visualization of TLC, HPTLC, and PLC plates can be reliably achieved in under two minutes, reducing subjective interpretations and inconsistencies. Automatic track recognition allows for the analysis of one or multiple plates at once. 【Features】 ■ Accurate TLC imaging ■ Quantitative analysis using a densitometer ■ Streamlined workflow integration ■ User-friendly design that facilitates operation in typical lab environments *For more details, please download the PDF or feel free to contact us.

  • Analytical Equipment and Devices

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mPAGE Mini Gel System

Providing solutions for protein electrophoresis and western blotting!

We would like to introduce our "mPAGE Mini Gel System." This system allows for the simultaneous production of up to two mini gels, enabling electrophoresis with high-resolution precast or hand-cast gels, and provides a leak-free solution for transferring to blotting membranes. The gel size is 8cm x 10cm, with thickness options of 0.75mm, 1.0mm, or 1.5mm, and you can choose between 10-well or 15-well formats for sample loading. 【Features】 ■ Designed for easy leak-free production of mini gels ■ Capable of performing electrophoresis using hand-cast and precast polyacrylamide gels ■ Offers excellent resolution and reduces experimental time *For more details, please download the PDF or feel free to contact us.

  • others

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Multiplex assay for proteins (simultaneous analysis of multiple items)

It is possible to quickly quantify multiple target proteins with a small sample size.

The "multiplex assay (simultaneous analysis of multiple items)" is a method that allows for the measurement of numerous samples and multiple proteins at once. With only a small sample volume of 25μL from serum, plasma, or cell culture supernatant, it is possible to rapidly quantify multiple target proteins. Additionally, the xMAP technology utilizes immune reactions to detect up to 500 different types of proteins per well. 【Features】 ■ It is possible to rapidly quantify multiple target proteins with a small sample volume of 25μL from serum, plasma, or cell culture supernatant. ■ It enables the simultaneous measurement of numerous samples and multiple proteins. *For more details, please download the PDF or feel free to contact us.

  • Other analyses

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Information about the "Basic Model Luminex200" campaign.

Pursuing ease of use! A basic model for rapid and accurate biomarker quantification.

We are running a limited-time campaign where you can purchase the basic model of the multiplex assay system, 'Luminex200', at a discounted price. This product supports both magnetic and non-magnetic bead immunoassays. With just 25μL of sample, it can analyze up to 100 types of analytes per well in a 96-well plate. Additionally, it features user-friendly programming capabilities and allows for sample ID input via a barcode reader. 【Campaign Details】 ■ Period: May 20, 2024 (Monday) to December 20, 2024 (Friday) ■ Desired campaign selling price: 7,770,000 yen (Regular desired selling price: 9,698,000 yen) - System (40-012J): 7,472,000 yen - Installation cost (MX-INSTALL): 298,000 yen *Prices are excluding tax. *For more details, please download the PDF or contact us through the details page for inquiries and registration.

  • Other physicochemical equipment

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AIDDISON: Harnessing the Power of AI for Drug Design Promotion and Optimization

Detailed information on features, idea generators, evaluation functions, security, and more!

This document introduces "AIDDISON," developed to facilitate the discovery and optimization process of compounds in drug development. It includes rich information on features such as projects, molecular libraries, and molecular sets, as well as idea generators like similarity search, virtual chemical space, and formoscore search. The content is designed to be easily referenced when considering implementation. Please feel free to download and take a look. 【Contents (partial)】 ■ Introduction ■ Features ■ Idea Generators ■ Evaluation Functions ■ SYNTHIA and Shopping Cart *For more details, please refer to the PDF document or feel free to contact us.

  • Software (middle, driver, security, etc.)

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AIDDISON: Harnessing the power of AI for drug discovery screening!

Confirming molecular interactions of desirable drug candidates, a new virtual drug discovery begins here.

AIDDISON" is a platform that combines artificial intelligence (AI) and computer-aided drug design (CADD) tools to integrate virtual screening in medicinal chemistry, scaffold hopping, identification of hit compounds, and optimization of lead compounds into one. Using generative methods and machine learning models trained on experimentally validated ADMET data, it guides the search in ultra-large chemical spaces and the de novo design of synthesizable compounds that resemble drugs. It also incorporates well-known robust chemical transformation rules in the SA-space. 【Features】 ■ De novo molecular design ■ Similarity and pharmacophore model searching ■ Shape-based searching ■ Molecular docking simulations For the synthesis of target compounds, we also recommend the retro-synthesis analysis software "SYNTHIA." *For more details, please refer to the PDF materials or feel free to contact us. If you wish to request a demo, please contact us and indicate "Demo Request.

  • Software (middle, driver, security, etc.)

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AIDDISON+ SYNTHIA Seamless Solution

From prediction to non-clinical trials! A complete drug design toolkit.

"AIDDISON + SYNTHIA" is a seamless software solution. Utilizing software integration to discover, optimize, and synthesize new molecules. By matching the generative AI "AIDDISON" for de novo design with the retro-synthetic analysis software "SYNTHIA," we bridge the gap between virtual concepts in chemistry and the real world. 【Features】 ■ Identification of lead compounds ■ Optimization of lead compounds ■ Planning of retro-synthesis ■ Optimization and scale-up *For more details, please refer to the PDF document or feel free to contact us.

  • Software (middle, driver, security, etc.)

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StripScan Digital Reading System for Test Strips

Free app for test strips. A web portal for management and sharing is also available!

We would like to introduce the 'StripScan Mobile Application' that we handle. This product processes data digitally, which minimizes variability from visual inspection, and it is a convenient web management tool that allows you to manage when and where measurements were taken on a map. Additionally, it reads results optically using a smartphone or tablet, so no special equipment is required (just the reference card attached to the test strip and your own smartphone), and it is a free-to-use application. The GPS feature shows where measurements were taken on the map, which is great news for fieldwork personnel. 【Features】 ■ Fast, accurate, and reproducible results - reliable digital results are obtained ■ Easy data management, traceability, and sharing of records and results ■ Currently, a versatile color reference card is provided at no additional cost with all compatible test strips ■ Free to use

  • Other measurement, recording and measuring instruments

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mPAGE Lux Casting System

Create ready-to-use SDS-PAGE gels in just 3 minutes! Uniform photopolymerization through system-controlled UV irradiation.

We would like to introduce the "mPAGE Lux Casting System" that we handle. This product enables rapid curing of mPAGE Lux Bis-Tris reagents using a quick casting workflow with UV irradiation, without the need for APS or TEMED. Additionally, due to the chemical properties of Bis-Tris gels, it allows for improved separation capability and reduced electrophoresis time. Please feel free to contact us if you have any inquiries. 【Features】 ■ Achieves highly reproducible results in a faster, simpler, and safer manner ■ Cures mini gels in 90 seconds ■ Reduces electrophoresis time ■ Uniform photopolymerization through system-controlled UV irradiation * For more details, please refer to the PDF materials or feel free to contact us.

  • Other physicochemical equipment

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Ultra-Pure Water and Pure Water Production Equipment Consumables Guide 2023

We will also introduce a complete set of all the necessary consumables for the year! A wide variety of options are available.

This catalog is the 2023 edition of the consumables guide for ultrapure water and pure water production systems handled by Merck KGaA. Various cartridges and filters are used in ultrapure water and pure water production systems, and we believe they are being replaced as needed. We hope to provide you with an understanding of the structure and function of the consumables and cartridges for ultrapure water and pure water production systems, as well as the importance of replacing consumables, so that you can utilize higher quality ultrapure water and pure water. [Contents (excerpt)] ■ Why replace consumables? ■ Milli-Q IQ 7003/05/10/15 ■ Milli-Q Integral ■ Milli-Q IQ 7000 ■ Milli-Q Advantage *For more details, please refer to the PDF document or feel free to contact us.

  • Other consumables

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Pure Water Production System 'Milli-Q HX 7040 SD'

Tank and water supply unit integrated! Goodbye to troubles with the weather resistance testing machine.

The "Milli-Q HX 7040 SD" is a pure water production system that can supply multiple accelerated weathering test machines with just one unit. Equipped with a long-life EDI module, it eliminates the costs and hassle of regenerating ion exchange resins, reducing running costs. To consistently remove silica, there are no lamp breakages or heater failures, avoiding sudden repair costs. 【Features】 ■ No scale buildup ■ Easier maintenance for heaters and lamps ■ Consistent removal of silica ■ Significant reduction in unnecessary expenses *For more details, please refer to the PDF document or feel free to contact us.

  • Weather resistance test

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How about an eco-friendly pure water production system? Green Program

Reduce CO2 by over 94%! Contribute to the environment by replacing pure water production equipment, while also keeping total costs down.

Update to the non-heating pure water production device 'Elix Essential' contributes to ISO 14001 and SDGs! This device uses a RO+EDI method that does not require heat or cooling water, with electricity costs equivalent to about one household fluorescent ceiling light. It is more stable than distilled water, with fewer inorganic ions, organic substances, and microorganisms, making it suitable for various pure water applications. Even if you purchase a new pure water production device, it offers excellent cost-effectiveness, allowing for early recovery of the initial investment. We are currently distributing materials that include cost estimates. 【Features of Elix Essential】 ■ Electricity costs equivalent to about one household fluorescent ceiling light ■ Usable for any pure water application ■ RO+EDI method that does not use heat or cooling water ■ Significant reduction in running costs and removal of silica *For more details, please refer to the PDF document or feel free to contact us.

  • Pure water production equipment

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DiluCult/DiluCult 2 (Liquid Medium Dispensing Device)

Three dispensing modes: high, standard, and high precision for food microbiological testing pre-treatment! Monitoring software is available.

"DiluCult (TM) / DiluCult (TM) 2" is a device that automatically measures samples during the pretreatment process of food microbiological testing (such as sample preparation) and prepares them to the appropriate dilution using buffer solutions. It is designed to facilitate work within clean benches and safety cabinets. It has a compact size and is equipped with a removable drip tray. Calibration is easy, and it can utilize a booster kit (additional pump) and monitoring software. By implementing it, the pretreatment process is streamlined, significantly increasing testing efficiency. 【Features】 ■ Three dispensing modes (high, standard, high precision) ■ Verified maximum weight capacity - DiluCult: 3,000g - DiluCult 2: 5,000g ■ Easy-to-use digital display and control panel ■ Booster kit (additional pump) available ■ DiluCult 2 is equipped with a robotic arm * DiluCult 2 is available for demonstration before purchase. * For more details, please refer to the PDF document or feel free to contact us.

  • Dispenser

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ESH Sample Homogenizer

Timer settings can be adjusted from 1 second to 1 hour for food microbiological testing preprocessing! It features a quiet brushless motor.

The "Enrichment Sample Homogenizer (ESH; Sample Homogenizer)" is a device designed to uniformly mix enrichment media and food inspection samples. It is equipped with a multifunctional display and control panel, allowing for four levels of speed settings. The mixing force can be adjusted, and the paddle section is compatible with autoclaves. By introducing the ESH, the preprocessing steps for food microbiological testing are streamlined, significantly increasing testing efficiency. Please feel free to contact us if you have any inquiries. 【Features】 ■ Uniformly mixes enrichment media and food inspection samples ■ Multifunctional display and control panel ■ Timer settings available (from 1 second to 1 hour) ■ Uses a quiet brushless motor ■ High safety drip tray ■ Paddle section is autoclave compatible * A demo unit is available for experience before purchase. * For more details, please refer to the PDF materials or feel free to contact us.

  • Homogenizer

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Assay kit for disease research and drug discovery.

We offer over 300 kits, including lipid metabolism assay kits provided by Roar Biomedical, as well as enzymes, neurotransmitters, and lipids.

Accurate and convenient measurement of biomolecules and metabolites is an essential process for disease research and drug development. Simple procedures not only reduce time but also prevent errors, yield highly reproducible results, and ultimately contribute to improved research efficiency. Under the Sigma-Aldrich® brand, we offer over 300 biomolecule assay kits, including lipid metabolism assay kits provided by Roar Biomedical. 【Features】 ■ A wide range of assay kits useful for disease research and drug discovery ■ Detection through colorimetric and fluorescent analysis utilizing enzyme reactions ■ Many products are compatible with high-throughput analysis using 96 well plates ■ Each lot has been tested for suitability ■ High sensitivity and reliability *For more details, please refer to the PDF document or feel free to contact us.

  • others

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Reducing the environmental impact: "Biodegradable surfactants"

Maintaining the quality and effectiveness of research results! Providing products to scientists to reduce environmental impact.

Have you ever considered the impact of the reagents used in research on the ecosystem? At Sigma-Aldrich, we are expanding our product range based on the concept of green chemistry as part of our efforts to achieve a sustainable and better society. Among surfactants, octyl- and nonyl-phenol ethoxylates (OPE, NPE) are designated as substances of very high concern (SVHC) under the REACH regulation established by the EU, due to their impact on health and the environment. The following biodegradable surfactants not only do not contain OPE/NPE, but are also chemically stable and break down into harmless substances after use, making them surfactants with low environmental impact. 【Features】 ■ Developed and improved to reduce environmental impact ■ Compliant with the 12 principles of green chemistry ■ Useful for the development of alternatives that reduce environmental burden *For more details, please refer to the PDF document or feel free to contact us.

  • Chemicals

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Standard substances for extractables and leachables (E&L) testing.

New product! A mixed solution and standard materials of certified reference materials (CRM) essential for ensuring reliability.

This product is a calibration mixture consisting of two solutions that facilitate the qualitative and quantitative analysis of extracts and infusions. The components included in the two mixed solutions are selected from a wide spectrum of compound classes relevant to E&L, considering their frequency of detection and toxicity in general E&L testing. Additionally, it is a certified reference material (CRM) manufactured under ISO/IEC 17025 and ISO 17034, which is crucial for ensuring customer reliability. 【Features】 ■ Certification of each component by quantitative NMR ■ Mixed solutions created following the ISO 17034 workflow ■ Testing for homogeneity and long-term stability using GC-MS ■ Traceability to NIST SRM ■ Provision of a comprehensive certificate including uncertainty *For more details, please refer to the PDF document or feel free to contact us.

  • Chemicals

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Environmental Analysis Product Guide

Measuring harmful substances related to soil, water, and air! A wide range of information and products useful for environmental analysis.

This catalog is the "Environmental Analysis Product Guide," which features a wide range of information and products useful for environmental analysis. We introduce a variety of products necessary for analyses related to soil contamination and waste treatment, as well as products needed for analyzing drinking water, industrial wastewater, hazardous air pollutants, and sick house syndrome. [Contents (Excerpt)] ■ Soil and Industrial Waste - Filters, solid-phase extraction, reagents, GC columns, HPLC columns, equipment ■ Water - Filters, solid-phase extraction, reagents, GC columns, HPLC columns, equipment ■ Air - Air sampling products, reagents, GC columns, HPLC columns, standard substances *For more details, please refer to the PDF document or feel free to contact us.

  • others

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[Material] Inhibitor Guidebook 1st Edition

"Enzyme inhibitors" and "glossary" published! Introduction of low molecular weight bioactive substances and their biological applications.

This document is the first edition of the Inhibitor Handbook. It has been created as a basic guideline for the use of inhibitors in biological research to serve as a reference for your studies. It includes information on "enzyme inhibitors," "receptor agonists & antagonists," and "how to use inhibitors: a technical guide." Please feel free to download and take a look. [Contents] ■ Enzyme Inhibitors ■ Receptor Agonists & Antagonists ■ How to Use Inhibitors: A Technical Guide ■ Glossary *For more details, please refer to the PDF document or feel free to contact us.

  • others

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Immunoassay Platform Catalog 2021

Features a "multiplex assay system" capable of simultaneously measuring up to 500 types of proteins!

This catalog introduces the "Immunoassay Platform" that our company handles. It features a "Multiplex Assay System" that can simultaneously measure up to 500 types of proteins with a small amount of sample, as well as a "High-Sensitivity Immunoassay System" and "Immunoassay Analysis Software." Additionally, information about free on-demand webinars is also included. [Contents] ■ Multiplex Assay System ■ High-Sensitivity Immunoassay System ■ Immunoassay Analysis Software ■ Conferma ELISA Kit ■ MILLIPLEX Multiplex Assay Kit ■ Free On-Demand Webinars *For more details, please refer to the PDF document or feel free to contact us.

  • Other analyses

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Proficiency test for the detection of SARS-CoV-2

The sample concentration range is wide, allowing the device's sensitivity to be tested across the dynamic range!

Testing for SARS-CoV-2 has become crucial for defense against the spread of the virus. With the increase in diagnostic methods, laboratories need to ensure the accuracy and reliability of SARS-CoV-2 testing applications using proficiency testing and other external quality assurance tools. This "SARS-CoV-2 Proficiency Testing Program" supports the quality assurance of your testing methods for detecting viral RNA using nucleic acid amplification techniques. 【Features】 - Not only reports qualitative results but also allows for flexible inclusion of quantitative values such as Cq (Ct) values for comparison. - Sample kits are manufactured based on ISO/IEC 17043 and ISO 13485. - Includes non-infectious liquid samples containing positive controls with a wide range of RNA copy numbers and negative controls. *For more details, please refer to the PDF document or feel free to contact us.

  • Other contract services

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Heating Desorption Tube (with Barcode) 'Carbotrap'

Using adhesive technology! Glass tube with frit in an optimal position.

"Carbotrap" is a heated desorption tube with a barcode that features easy-to-read markings on a stainless steel tube. It utilizes our adsorption technology throughout. The back pressure between the tubes is constant, and the pre-conditioned tubes are sealed with a TDS storage container or brass end caps. 【Features】 ■ Utilizes our adsorption technology throughout ■ Constant back pressure between the tubes ■ Easy-to-read markings on the stainless steel tube ■ Glass tube with frit located in an optimal position ■ Easy-to-read barcode that withstands many pre-conditioning cycles *For more details, please refer to the PDF document or feel free to contact us.

  • tube

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TLC Thin Layer Chromatography Comprehensive Catalog 2021

We offer a lineup of plates that utilize various carriers, sizes, and supports!

This catalog introduces our "TLC Thin Layer Chromatography" products. We offer TLC plates that combine excellent strength and surface smoothness, guaranteeing the highest level of reliability. By providing a lineup of plates that utilize a variety of carriers, sizes, and supports, we can meet our customers' diverse needs and stringent usage conditions. [Contents (Excerpt)] ■ TLC Plate Selection Guide ■ Seven Key Points to Keep in Mind for TLC Experiments ■ Unmodified Silica Gel TLC Plates ■ HPTLC (High-Performance Thin Layer Chromatography) Plates ■ LiChrospher (Spherical Silica Gel) HPTLC Plates *For more details, please refer to the PDF document or feel free to contact us.

  • Testing Equipment and Devices

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F5 HPLC/UHPLC column

Separating structural isomers and related compounds through multiple interactions (MIX mode)!

We would like to introduce our "F5 HPLC/UHPLC Columns." These columns retain high-polarity basic compounds without the use of ion-pair reagents. They can separate related compounds such as metabolites. Additionally, they improve MS sensitivity by retaining compounds at high organic solvent concentrations, and 100% water mobile phase solvents can be used. 【Features】 ■ Retains high-polarity basic compounds without ion-pair reagents ■ 100% water mobile phase solvents can be used ■ Improves MS sensitivity by retaining compounds at high organic solvent concentrations ■ Can separate related compounds such as metabolites *For more details, please refer to the PDF document or feel free to contact us.

  • Testing Equipment and Devices

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Proficiency test for quantitative NMR (qNMR)

Would you like to participate in the quick turn study of the skills test to confirm your techniques and abilities in qNMR measurements?

Once the account setup for the online PT portal is complete, you will receive PT samples and reports. Instructions for sample preparation and report creation can also be confirmed from the PT portal. The samples contain dimethyl sulfone as the main component. The purity value is determined by quantitative 1H NMR (nuclear magnetic resonance). After the analysis is completed, please submit the analysis results from the PT portal within 45 days. 【Flow of the Proficiency Test】 1. Registration & Order 2. Delivery 3. Start of Testing 4. Reporting 5. Data Processing 6. Evaluation Report *For more details, please refer to the PDF materials or feel free to contact us.

  • Other contract services

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Drug "Supel BioSPME 96-Pin Devices"

Measurement methods for plasma protein binding! They excel in speed and simplicity.

The "Supel BioSPME 96-Pin Devices" are superior in speed and convenience compared to traditional sample preparation methods used in plasma protein binding tests. They offer high reproducibility between lots and among 96-well samples. They have three times the throughput performance compared to Rapid Equilibrium Dialysis (RED). They boast a higher phospholipid removal rate than Rapid Equilibrium Dialysis (RED) and can accommodate both simple manual use and complete automation with machines. 【Features】 ■ Reduced working time ■ Lipid removal ■ Automation capable ■ Accuracy and precision ■ Good reproducibility *For more details, please refer to the PDF document or feel free to contact us.

  • Other laboratory equipment and containers

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Solid Phase Extraction Product Catalog

The guide for solid phase extraction (SPE) is included, featuring silica-based and diatomaceous earth-based materials.

This catalog introduces the "Solid Phase Extraction Products" handled by our company. It includes a guide on the usage of Solid Phase Extraction (SPE), as well as silica-based, diatomaceous earth-based, polymer-based, carbon-based products, and accessories (such as empty tubes and frits). Please use this for selecting products. [Contents (excerpt)] ■ Solid Phase Extraction (SPE) Usage Guide ■ Silica-based ■ Diatomaceous earth-based ■ Disk type (ENVI-Disk) ■ Polymer-based *For more details, please refer to the PDF document or feel free to contact us.

  • Other physicochemical equipment

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China National Standard Specifications - HPLC Analysis Related Product Guide for Chinese Pharmacies

Including HPLC measurements, such as the HPLC measurement of metoprolol tartrate in sustained-release tablets!

This document is a guide to HPLC analysis related products for Chinese national standard specifications and Chinese pharmacies that our company handles. It includes HPLC measurements of the pesticide imidacloprid in green tea using the Discovery HS C18 column, HPLC measurements of metoprolol tartrate in extended-release tablets, and HPLC measurements of residual chlormequat in milk. Please take a moment to read it. [Contents] ■ HPLC measurement of the pesticide imidacloprid in green tea using the Discovery HS C18 column ■ HPLC measurement of metoprolol tartrate in extended-release tablets using the Purospher STAR RP-18e column ■ HPLC measurement of residual chlormequat in milk using the Discovery HS C18 column *For more details, please refer to the PDF document or feel free to contact us.

  • Analytical Equipment and Devices

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Silica gel lipid removal agent "HybridSPE DPX Chip"

Making solid-phase extraction easier! Introducing a zirconia-coated silica gel lipid removal agent.

The "HybridSPE DPX chip" is a zirconia-coated silica gel lipid removal agent that does not fix the HybridSPE stationary phase within the chip. The internal HybridSPE stationary phase is a filler developed for the purpose of removing phospholipids derived from biological sample matrices in LC-MS analysis. The dispersed pipette extraction provides automated INTip (in-chip) sample preparation. 【Features】 ■ Customizable ■ High efficiency ■ Low sample volume ■ Reduction of chromatographic solvents *For more details, please refer to the PDF document or feel free to contact us.

  • Other consumables

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Supelco Smart Solid Phase Microextraction Fiber

Are you automating SPME? All products can be used with the PAL auto-sampler system.

The "Supelco Smart Solid Phase Microextraction Fiber" combines our SPME products such as Carboxen, two-layer coated, and surface-protected fibers with Smart technology for seamless compatibility. It records usage parameters such as stroke count, operation date, and temperature exposure. It automatically adopts parameters suitable for various SPME fibers. 【Features】 ■ Traceability - Records usage parameters such as stroke count, operation date, and temperature exposure ■ Ease of Use - Automatically adopts parameters suitable for various SPME fibers ■ Increased Productivity - Complete automated sampling *For more details, please refer to the PDF document or feel free to contact us.

  • Other physicochemical equipment

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HybridSPE Phospholipid Solid Phase Extraction Column

No preconditioning required! Introducing zirconia-coated silica gel lipid remover.

The "HybridSPE Phospholipid Solid Phase Extraction Column" is a zirconia-coated silica gel lipid removal agent that can shorten the sample preparation time. It has a retention mechanism that allows for the separation of hydrophobic components from phospholipids. It eliminates ionization suppression caused by proteins and phospholipids. Additionally, it serves as an alternative to the traditional complex SPE methods with a simple approach similar to conventional protein precipitation methods. 【Features】 ■ Improved reproducibility ■ Reduced contamination of detectors, extending the lifespan of LC columns ■ Shortened sample preparation time ■ Automation capable, compatible with general robotic systems ■ No preconditioning required *For more details, please refer to the PDF document or feel free to contact us.

  • Other consumables

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