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アンチエイジング

Establishment2012年8月8日
addressTokyo/Minato-ku/3-4-6 Minami Aoyama, AOYAMA346 3F
phone03-3478-0248
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last updated:Apr 10, 2026
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RS Liposome 3.0E NMN RS Liposome 3.0E NMN
RS Liposome 3.0E Complex RS Liposome 3.0E Complex
RS Liposome 3.0 Complex RS Liposome 3.0 Complex
RS Liposome 1.0 / 3.0 / 5.0 RS Liposome 1.0 / 3.0 / 5.0
Pentide-NMN(Penetrating NMN derivative) Pentide-NMN(Penetrating NMN derivative)
Pentide-C(Penetrating vitamin C derivative) Pentide-C(Penetrating vitamin C derivative)
RemyEV(Hybrid exosomes) RemyEV(Hybrid exosomes)
RemyStem(Human stem cell conditioned medium) RemyStem(Human stem cell conditioned medium)
RS Mixture 9.6E RS Mixture 9.6E
RS Exosave(Exosome protection technology) RS Exosave(Exosome protection technology)
About the lineup About the lineup
Pentide-C(Penetrating

Pentide-C(Penetrating vitamin C derivative)

"Pentide-C" is a vitamin C derivative stabilized by attaching a peptide to the hydroxyl group of vitamin C. What significantly differentiates it from conventional derivatives is that the attached peptide has functional properties. The peptide in "Pentide-C" penetrates the stratum corneum while remaining bound to the vitamin C. Because vitamin C and the peptide are bound by a peptide bond, this bond is hydrolyzed by peptidase. As a result, the vitamin C is easily released into a free state.

Penetrating peptide vitamin C derivative 'Pentide-C'

Possesses antibacterial properties against Staphylococcus aureus! Vitamin C becomes free.

"Pentide-C" is a stabilized vitamin C derivative that combines peptides with the hydroxyl group of vitamin C. Since vitamin C and peptides are linked by peptide bonds, after being taken up by cells, this bond undergoes hydrolysis by proteases. As a result, vitamin C becomes free, and data shows that its bioavailability is higher at low concentrations compared to pure vitamin C. [Features] ■ Penetration into the skin ■ Uptake by cells ■ Collagen production ■ Inhibition of melanin production ■ Antibacterial against Staphylococcus aureus *For more details, please refer to the PDF document or feel free to contact us.

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【Information】Vitamin C derivative Pentide-C with high bioavailability.

Significant differences confirmed with a formulation amount of 0.0005%! Technical documentation including results from human clinical trials is also published.

This document is a technical material summarizing the functionality and safety data of the vitamin C derivative "Pentide-C," which utilizes cell-permeable peptides. In addition to explanations regarding its high bioavailability, it includes a wide range of verification data such as selectivity of cell membranes, cytotoxicity tests, effects on hybrid exosomes, and results from human clinical trials. Improvements in wrinkles, skin brightness, and melanin index have also been confirmed, making it a useful reference for product development. [Contents] ■ High bioavailability ■ Selectivity of cell membranes ■ Cytotoxicity ■ Effects on hybrid exosomes ■ Uptake by host cells ■ Human clinical trial results of Pentide-C *For more details, please download the PDF or feel free to contact us.

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[Data] New vitamin C derivative combined with human stem cell culture fluid.

Functionality exceeding that of vitamin C at low concentrations! An explanation of a novel derivative utilizing cell membrane permeable peptides.

This document is a technical report that provides a detailed explanation of the characteristics and functionality of the vitamin C derivative "Pentide-C." It includes verification results on skin permeability and cell membrane permeability, as well as test data related to collagen production promotion, anti-inflammatory effects, melanin production suppression, and antibacterial effects, presented alongside charts and graphs. As a new approach to enhance the bioavailability of vitamin C, we hope this will be useful in selecting cosmetic ingredients. [Contents] ■ Characteristics of Pentide-C (skin permeability, cell membrane permeability) ■ Functionality of Pentide-C (promotion of collagen production, anti-inflammatory effects, melanin production suppression, antibacterial effects) ■ Stability of Pentide-C ■ Discussion *For more details, please download the PDF or feel free to contact us.

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Whitening solution using Pentide-C for cosmetic development.

Significant difference with a 0.0005% formulation! Supporting the development of whitening cosmetics.

In the cosmetics industry, pursuing whitening effects is crucial for meeting consumer needs. In particular, addressing skin concerns such as spots, freckles, and dullness requires the formulation of effective ingredients and technologies that maximize their effects. Pentide-C supports the resolution of challenges in the development of whitening cosmetics as a highly bioavailable vitamin C derivative. 【Usage Scenarios】 - Cosmetics that promote whitening effects - Anti-aging products - Products that enhance skin brightness and transparency 【Benefits of Introduction】 - Evidence of effectiveness based on human clinical trial results - Contributes to improvements in wrinkles, skin brightness, and melanin index - Creation of differentiation elements in product development

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