アンチエイジング Product Lineup

"RemyStem-JP" is a conditioned medium rich in protein components secreted by stem cells when adipose-derived stem cells are isolated and cultured from adipose tissue. Adipose-derived stem cells are a type of adult stem cell that can be more easily obtained than bone marrow-derived stem cells or umbilical cord blood-derived stem cells. Additionally, due to the high content of stem cells, they have been increasingly utilized in recent years as materials for regenerative medicine and cosmetics. 【Features】 ■ Anti-aging effects on aging cells ■ Promotion of collagen and hyaluronic acid biosynthesis ■ Whitening effects ■ Hair growth and thickening effects *For more details, please refer to the PDF document or feel free to contact us.

"RemyStem" is a product that uses active substances such as "growth factors" and "exosomes" produced by stem cells as cosmetic ingredients. It can be provided in various forms, including standalone stem cell culture fluid, liposome processing, and mixtures with materials such as vitamin C derivatives. It controls the profile of physiologically active substances through biomimetic stimulation. 【Features】 ■ No animal-derived serum used ■ No antibiotics used ■ No hormones used ■ Controls the profile of physiologically active substances through biomimetic stimulation ■ Manufacturing standards based on MFDS guidelines *For more details, please refer to the PDF materials or feel free to contact us.

Stem cell exosomes contained in stem cell culture medium are expected to have high beauty effects as vesicles responsible for intercellular information transmission. Our "RemyStem" and "RS Mixture 9.6E" achieve approximately ten times the usual exosome secretion amount through rolling bottle culture technology. We have demonstrated a rich exosome content through data from nano-tracking analysis and ELISA analysis (CD9, CD63 markers). Furthermore, we have abundant in vitro data on the rejuvenation effects of aged fibroblasts, promotion of hyaluronic acid and collagen biosynthesis, and suppression of melanin production. We provide suitable solutions for companies considering the development of high-function anti-aging cosmetics focused on evidence, as well as cosmetics for clinics. We are also flexible in responding to prototype development and formulation consultations. 【Features】 ■ Tenfold exosomes through rolling bottle culture ■ Presentation of quantitative data such as nano-tracking analysis ■ Proven promotion of collagen and hyaluronic acid production ■ Abundant evidence for anti-wrinkle and melanin suppression *For details, please check "Download Catalog."

Prioritizing safety as a cosmetic ingredient, our human stem cell conditioned medium "RemyStem" and exosome materials are produced under strict manufacturing management. In the manufacturing process, we do not use any animal-derived serum, antibiotics, or hormones, and we adopt rolling bottle culture using a highly safe serum-free medium. Furthermore, we comply with stringent manufacturing standards based on the MFDS (Ministry of Food and Drug Safety of Korea) guidelines, and we have cleared all nine items of cosmetic safety evaluation tests, including human skin patch tests, single-dose oral toxicity tests, eye mucosa irritation tests, skin sensitization tests, and genotoxicity tests. Major and medium-sized cosmetic manufacturers that prioritize risk avoidance and quality assurance, as well as OEM companies dealing with doctor's cosmetics, can adopt our products with confidence. 【Features】 ■ No animal-derived serum, antibiotics, or hormones used ■ Cleared all nine cosmetic safety tests ■ Strict manufacturing and quality control in accordance with MFDS standards ■ High safety demonstrated through patch tests and toxicity tests *For more details, please check "Download Catalog."

The stem cell exosomes secreted from human adipose-derived stem cells, which are gaining attention in the field of regenerative medicine, are vesicles (50-150 nm) responsible for intercellular communication and play an essential role in wound healing and cell activation. Our "RemyStem" series contains a high concentration of growth factors (such as EGF, FGF, VEGF) and functional exosomes through unique biomimetic stimulation and rolling bottle culture. By adding it to fibroblasts artificially aged by ultraviolet light, the reverse aging effect that suppresses the secretion of SA-β-GAL and resumes cell division has been demonstrated. It is a premium anti-aging care ingredient that covers wrinkle improvement, whitening, and strengthening the skin barrier. 【Features】 ■ High-quality exosomes from human adipose-derived stem cells ■ Optimization of ingredients through biomimetic stimulation ■ Reverse aging of aged fibroblasts ■ Rich in growth factors and functional proteins *For more details, please check by downloading the catalog.

In the planning and development of new products, early sample evaluation and stability testing are key to success. Our company offers various sample materials of exosome ingredients tailored to your development concept, including high-concentration exosome-containing material "RemyStem," "RS Mixture 9.6E" compliant with full ingredient labeling, and the high-penetration liposome "RS Liposome" series. As a liquid material, it can be easily blended into a wide range of formulations, from serums and lotions to creams and professional introduction agents. We also support small lot sizes from 1kg to 5kg and provide technical documentation and various evidence data, ensuring speedy backup from the prototype stage to commercialization. Please feel free to request more information. 【Features】 ■ Rapid shipping of raw material samples convenient for evaluation and prototyping ■ Applicable to a variety of formulations such as serums and creams ■ Support for small lot introduction and prototyping consultations starting from 1kg ■ Simultaneous provision of necessary technical data and specifications for blending *For details, please check "Download Catalog."

Anti-Aging Co., Ltd. is a specialized manufacturer of high-performance aging care ingredients, delivering high-quality human stem cell conditioned medium "RemyStem" at an affordable price with a reliable supply system. Our "RemyStem" involves the careful selection and uniform separation and cultivation of adipose-derived stem cells. By adopting our unique know-how of "Rolling Bottle Culture," which rotates bottles 24 hours a day while providing oxygen, physical, and pharmacological stimuli, we have increased the amount of secreted proteins and functional exosomes to about ten times that of conventional culture methods. With quality assurance, traceability, and technical support unique to direct sales from a raw material manufacturer, we strongly support the development of your products. 【Features】 ■ Direct sales and stable supply from a raw material specialized manufacturer ■ Approximately ten times the effective ingredient amount through Rolling Bottle Culture ■ Established technology for uniform separation and purification of adipose-derived stem cells ■ Technical support and data provision unique to the manufacturer *For details, please check "Download Catalog."

We offer a "RemyStem" raw liquid lineup that does not involve dilution or excessive processing, specifically for salon-use introduction liquids and high-end anti-aging beauty serums. This lineup is concentrated with various growth factors such as VEGF, TGF-β, FGF, and IGF-1, which are secreted during the culture process of fat-derived stem cells, as well as enzyme proteins like collagen, hyaluronic acid, and SOD. It effectively prevents skin aging and damage while strongly activating the proliferation of fibroblasts and keratinocytes. In addition to the raw liquid zone, you can choose from a wide range of grades, including liposome zones (RS Liposome 1.0/3.0/5.0) that enhance biocompatibility according to your application and budget, as well as high-concentration zones using EXO-SAVE technology. 【Features】 ■ High-purity human stem cell conditioned culture liquid raw liquid specification ■ Rich in growth factors (EGF, FGF, etc.) and physiologically active substances ■ A wide range of grades from raw liquid to liposome processing ■ Suitable for professional beauty equipment introduction liquids and high-end beauty serums *For more details, please check "Download Catalog."

We introduce cosmetic active ingredients that apply advanced biotechnology and regenerative medicine research. Our "RemyStem" and related materials are active components that not only provide superficial hydration but also directly act on cell receptors and signaling pathways. In in vitro experiments, data has shown that they enhance the proliferation and migration ability of human keratinocytes (HaCaT), strengthening skin barrier function, suppress melanin production in melanocytes, and induce the expression of vimentin and growth factors (KGF, IGF-1, etc.) that promote hair growth, demonstrating multifaceted physiological activity applicable in scalp care and hair growth fields. They are well-suited for concept cosmetics that emphasize functionality. 【Features】 ■ Enhances the migration ability of keratinocytes and strengthens skin barrier function ■ Strong melanin suppression against melanocyte stimulation ■ Hair growth and scalp care through vimentin expression and KGF promotion ■ Active ingredients that directly approach cell signals *For more details, please check "Download Catalog."

In the aging care market, where customer needs are becoming more sophisticated, it is essential to have reliable material selection and advanced formulation development technology to create products that can compete successfully. Our company offers a comprehensive lineup of advanced premium materials with solid evidence, including human stem cell conditioned media "RemyStem," exosomes compliant with full ingredient labeling "RS Mixture 9.6E," high-penetration vitamin C "Pentide-C," and skin longevity ingredient "Pentide-NMN." We propose combinations of raw materials and formulation balances tailored to target demographics and price ranges (cost design) for clinic-exclusive products, professional salon materials, and D2C brands. We provide total support, from stability testing to solving formulation challenges. **Features** - A range of materials covering stem cells, exosomes, VC, and NMN - Suitable formulation proposals based on target demographics and costs - Technical know-how regarding stability and compatibility during formulation - One-stop solutions for OEM manufacturing and formulation development challenges *For more details, please check "Download Catalog."*