Methods of Utilization and Application Fields of FANA Phosphoroamidite
FANA phosphoramidite reagents from Sapala Organics The FANA (2'-fluoro-arabinonucleic acid) phosphoramidites listed in this catalog are as follows: (1) FANA-A(Bz) amidite CAS 2882846-29-7 (2) FANA-G(iBu) amidite CAS 1404463-20-2 (3) FANA-C(Bz) amidite CAS 159414-99-0 (4) FANA-T amidite CAS 208193-48-0
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Utilization and Research Fields FANA-modified nucleic acids have the following advantages compared to conventional DNA/RNA and are utilized in various research and development fields: Improved Stability • High resistance to RNase, suppressing degradation in vivo • Structure suitable for long-term storage and in vivo administration Enhanced Binding Affinity • High hybridization efficiency with target RNA • Ideal for siRNA, antisense, and aptamer development Application Fields • Auxiliary nucleic acids for mRNA pharmaceuticals • Oligonucleotides for gene therapy • Epigenetics research • NGS library construction Strengths of Sapala Organics • Manufacturing system certified with ISO 9001 / ISO 27001 • Comprehensive support from R&D to GMP manufacturing • Flexible research support through FFS (Fee for Service) and FTE (Full Time Equivalent) contracts • Robust custom synthesis and technical support
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Ayurveda is well-known, but historically, India has been significantly involved with "medicine." Sapala Organics was established in 2005 in Hyderabad, located in the central part of the Deccan Plateau. The state government is actively investing to make this area a "Pharma City" (a treasure trove of medicine). Sapala has gained recognition from major pharmaceutical companies in the United States and Europe, steadily achieving results. To further provide the technological capabilities developed globally to Japan, Sapala Corporation was established in February 2018 as a local subsidiary in Japan. Recently, the Japanese government has also been focusing on projects that promote advanced pharmaceutical development and drug discovery, including nucleic acid-related drugs. We encourage you to consider the technological expertise of "Sapala," which excels in these fields.
