Cytiva List of Products and Services

The "VacuCap Filtration Sterilization Bottle Top Filter" is a revolutionary bottle top filter designed for rapid filtration sterilization of aqueous solutions ranging from 100 mL to 5 L and for the removal of mycoplasma. This filter minimizes plastic waste and is environmentally friendly, compatible with various collection containers, and helps reduce storage space and waste volume. 【Features】 - High flow rate achieved using Supor membrane - Removal of mycoplasma with a pore size of 0.1 μm - Filtration sterilization of culture media and supplements with a pore size of 0.2 µm - No need for additional injection into the upper liquid reservoir; direct suction from mixing containers is possible - Direct filtration into storage containers reduces contamination risk - Used as pre-filtration for exosome purification to remove microvesicles (0.1 µm, 0.2 µm) As an example of application, the 0.1 µm VacuCap is used for the clarification of supernatant from the culture of NIH3T3, a mouse embryonic fibroblast, as a preliminary step for concentrating and purifying exosomes. [1] Ji, H. et al., Electrophoresis. 29. 2660-2671

The "Acrodisc Sterile Syringe Filter" features a Supor membrane made of PES, making it a versatile filter syringe for sterilization with high flow rates and low protein adsorption. Gamma-ray sterilization eliminates potential contamination from residual EOG. The Acrodisc PF and Sealam Acrodisc syringe filters are equipped with a unique pre-filter that increases the processing capacity for highly viscous solutions such as serum. Available in a wide range of sizes, it can accommodate sample volumes from 10 mL to 200 mL. 【Features】 ■ Excellent flow characteristics and high filtration capacity ■ Low protein adsorption minimizes sample loss ■ Gamma-ray sterilization eliminates potential contamination from residual EOG ■ A wide range of sizes (13 mm to 37 mm) available, accommodating sample volumes from 10 mL to 200 mL ■ The Acrodisc PF and Sealam Acrodisc syringe filters include a unique pre-filter that increases processing capacity for difficult-to-filter solutions ■ Mycoplasma removal using a pore size of 0.1 μm *For more details, please refer to the PDF document or feel free to contact us.

The "Acrodisc Syringe Filter - Versapor Membrane" can meet the needs for pre-filtration and clarification of various aqueous solution samples. It features a durable membrane that is flexible regardless of wet or dry conditions. It guarantees non-heat generation and biological safety. It is effective for pre-filtration of samples containing many fine particles, serum filtration, and dissolution tests, protecting equipment from particle accumulation. 【Features】 ■ Meets the needs for pre-filtration and clarification of various aqueous solution samples ■ Durable membrane with flexibility regardless of wet or dry conditions ■ Guarantees non-heat generation and biological safety *For more details, please refer to the PDF document or feel free to contact us.

The "DMSO Safe Acrodisc Syringe Filter" features a polypropylene housing and nylon membrane that are resistant to solutions containing DMSO. It has excellent chemical compatibility with esters, bases, and alcohols. The effective filtration area is 2.8 cm², and the maximum operating temperature is 55°C. 【Features】 ■ Resistant to DMSO ■ Polypropylene housing and nylon membrane resistant to solutions ■ Excellent chemical compatibility with esters, bases, and alcohols *For more details, please refer to the PDF document or feel free to contact us.

The NanoSep MF centrifugal filtration device is a 1.5 mL tube-style filter equipped with wwPTFE (highly hydrophilic PTFE). It is useful for the pretreatment of small amounts of analytical samples, capable of high-speed rotation at 14,000xg, allowing for rapid sample filtration. Features: ● Rapid sample processing: Designed for use in centrifuges, it can simultaneously centrifuge multiple samples. ● Versatile membrane filter: Built with a wwPTFE (highly hydrophilic PTFE) membrane, it has chemical resistance to aqueous solutions, organic solvents, and corrosive organic solvents. ● High recovery rate: The wwPTFE membrane has low protein adsorption, effectively removing unwanted particles from samples while achieving high recovery rates of valuable proteins. ● Low leachables: HPLC-grade centrifuges have been proven to have low levels of leachables that absorb UV. ● Leak-free structure: With a unique sealing technology, it guarantees no sample leakage by avoiding the use of potentially contaminating materials such as O-rings or adhesives.

Filtration of samples and mobile phases is a simple and efficient method necessary to extend the lifespan of consumable parts for HPLC, reduce wear and damage to the system, and maintain the integrity of the HPLC system. Acrodisc syringe filters offer the ideal membrane materials for your samples. The hydrophilic membranes made of nylon, PVDF, and Supor (PES) membranes are suitable for aqueous (water-based) samples. The hydrophobic PTFE membrane repels water and is inert to aggressive organic solvents, making it ideal for gases and organic solvents. The highly hydrophilic PTFE membrane is a versatile membrane that can be used for both aqueous and organic solvent applications.

The Solvback Filter Holder is used for the removal of contaminating particles from the mobile phase and for degassing. It can filter up to 4 liters of mobile phase solvent at once, eliminating the need to top up the filter funnel. After installing the Solvback Filter Holder in a vacuum container and connecting it to a vacuum source, filtration begins by placing the inlet tube into the solvent to be filtered. Made of durable polypropylene, it is compatible with common HPLC mobile phase solvents such as methanol, acetonitrile, and tetrahydrofuran. The surfaces of the filter holder that come into direct contact with the mobile phase are all made of polypropylene. Features ● Highly versatile design that fits most HPLC bottles, flasks, and containers ● Direct suction from HPLC solvent bottles ● Made of shatter-resistant plastic ● Patented magnetic sealing

The "AcroPak Capsule Filter - Supor Membrane" is suitable for solutions that require high flow rates, high filtration capacity, and low protein adsorption. The lineup includes "AcroPak 20 - Supor," "AcroPak 200 - Supor," and "AcroPak 500, 1000, 1500 - Supor." The built-in pre-filter extends the filtration lifespan when processing high-viscosity solutions or solutions containing a large number of fine particles (such as media containing serum). 【Lineup】 ■ AcroPak 20 - Supor ■ AcroPak 200 - Supor ■ AcroPak 500, 1000, 1500 - Supor *For more details, please refer to the PDF document or feel free to contact us.

The "AcroPak Capsule Filter - Supor EKV Membrane" extends product life due to the Mach V asymmetric membrane, while demonstrating maximum flow rate and throughput performance. The "AcroPak 20 - Supor EKV," designed for small to medium volume filtration, is disposable, reducing operational and related costs. It is suitable for filtering fluids containing low concentrations of proteins, preservatives, and other important components, making it ideal for filtering aqueous solutions, cell culture media, and serum. 【AcroPak 20 - Supor EKV Features】 ■ Design suitable for small to medium volume filtration ■ Product is disposable ■ System is scalable ■ Testing during scale-up can be significantly reduced ■ Testing costs are greatly reduced *For more details, please refer to the PDF document or feel free to contact us.

The "AcroCap Pressure Filtration Device" provides rapid pressure filtration for medium-capacity aqueous solutions at the laboratory level. It prevents air locks with a complete hydrophobic air vent mechanism. The inlet can be connected to a 6.4 mm tube or various male luer slips, making it compatible with most pressure systems. 【Features】 ■ Prevents air locks with a complete hydrophobic air vent mechanism ■ Removes mycoplasma (0.1 μm pore size) ■ Compatible with most pressure systems ■ The inlet can be connected to a 6.4 mm tube or various male luer slips *For more details, please refer to the PDF document or feel free to contact us.

The "Mini Profile Capsule" is a depth capsule designed for scale-up applications, utilizing high dust collection capacity depth media. It achieves a highly reliable absolute filtration accuracy. It features a unique design that combines the advantages of thick depth filters and conventional wide-area pleated filters. Additionally, it has a wide range of chemical resistance, is suitable for high-viscosity fluids, and offers two types of cartridge filters. 【Features】 ■ Uses high dust collection capacity depth media ■ Wide range of chemical resistance ■ Suitable for high-viscosity fluids ■ Achieves highly reliable absolute filtration accuracy ■ Provides two types of cartridge filters *For more details, please refer to the PDF document or feel free to contact us.

The "Supracap 50&100 Depth Filter Capsule" efficiently removes various sizes of cells, tissue fragments, and more, using three types of high-performance Seitz depth filter media. The "Seitz Bio 20 Media" is made of high-purity unmodified and modified cellulose membranes, free of inorganic materials. The "Seitz P Series Media" consists of cellulose fibers, filtration aids, and resins. Additionally, the "Seitz HP Series Media" is suitable for filtering solutions containing a high number of dead cells or solids, as well as solutions with particles of various sizes. 【Features of Seitz Bio 20 Media】 ■ High-purity unmodified and modified cellulose membranes, free of inorganic materials ■ Suitable for processing samples with ion sensitivity, such as protein solutions and dialysis fluids ■ Effective in protecting analytical applications such as columns through filtration *For more details, please refer to the PDF document or feel free to contact us.

The "Polypropylene/Polyethylene Separator Depth Filter" has high chemical resistance and excellent wet strength. By using it in conjunction with submicron membrane filters, the total flow rate is improved due to the liquid channeling effect. It can be folded and handled similarly to laboratory filter paper. 【Features】 ■ High chemical resistance ■ Improved total flow rate due to the liquid channeling effect when used with submicron membrane filters ■ Excellent wet strength ■ Can be folded and handled similarly to laboratory filter paper *For more details, please refer to the PDF document or feel free to contact us.

The "Scale-Up Acrodisc Syringe Filter" is a laboratory-scale sterilization device made from the same materials as large-capacity capsule filters and cartridge filters. It includes options suitable for filtering solutions that require low protein adsorption characteristics, such as "Supor (PES)," which offers high flow rates and throughput performance, and "Fluorodyne II," which is suitable for applications that require PVDF membranes. It is ideal for small-volume sterilizing filtration, determining product compatibility and recovery, and conducting preliminary filtration performance tests. 【Product Lineup】 ■Supor ■Supor EKV ■Fluorodyne II ■Ultrapore ■Posidyne *For more details, please refer to the PDF document or feel free to contact us.

The "Acrodisc Syringe Filter - Mustang E Membrane" is a product equipped with a membrane that has a pore size of 0.2 μm, featuring hydrophobic interaction groups and anionic exchange groups. It removes endotoxins from water, buffers, neutral sugar solutions, and some biological solutions. It demonstrates high endotoxin binding capacity with minimal influence from the salt concentration and pH of the filtered solution. 【Features】 ■ Equipped with a membrane that has a pore size of 0.2 μm, featuring hydrophobic interaction groups and anionic exchange groups ■ Removes endotoxins from water, buffers, neutral sugar solutions, and some biological solutions ■ Less affected by the salt concentration and pH of the filtered solution ■ Shows high endotoxin binding capacity *For more details, please refer to the PDF document or feel free to contact us.

The "Polypure Capsule" is a high-density all-polypropylene pre-filter that extends the filtration lifespan of the final filter. Since all components are made of polypropylene, it achieves excellent chemical resistance and low extractables levels. The melt media and thermal bonding structure protect the purity and integrity of the filtrate. 【Features】 ■ All components are made of polypropylene ■ Achieves excellent chemical resistance and low extractables levels ■ Melt media and thermal bonding structure protect the purity and integrity of the filtrate ■ High dust-holding capacity improves filtration volume, especially when using high-viscosity solutions, extending the filtration lifespan of the final filter ■ Listed as compliant with materials that come into contact with food under 21CFR ■ High flow rate *For more details, please refer to the PDF document or feel free to contact us.

The "Filtration Sterilization and Clarification Disk Membrane Filter" can be widely used for various applications such as clarification filtration, pre-filtration, filtration sterilization, and virus removal. Scaling up is easy, reducing the need for re-qualification. The membrane's material composition is the same as that of large capsules and cartridge filters, so there is no need to change the material composition when transitioning from pilot scale to production scale. 【Features】 ■ The membrane's material composition is the same as that of large capsules and cartridge filters ■ Scaling up is easy, reducing the need for re-qualification ■ No need to change the material composition when transitioning from pilot scale to production scale *For more details, please refer to the PDF document or feel free to contact us.

The "37 mm Bacteria Air Vent" is a compact vent filter. It features a hydrophobic glass fiber laminated membrane with a pore size of 1 μm. It reduces the cross-contamination of glass fibers derived from the filter material. Additionally, you can choose between two types: gamma-irradiated sterilized and non-sterilized. 【Features】 ■ Compact ■ Uses a hydrophobic glass fiber laminated membrane ■ Reduces glass fiber cross-contamination ■ Available in two types: gamma-irradiated sterilized and non-sterilized *For more details, please refer to the PDF document or feel free to contact us.

The "Acro 37 TF Vent Device" is a 37 mm vent filter that uses a PTFE membrane with a pore size of 0.2 μm. It is an unsterilized type that can be autoclaved at 121-123°C for up to 20 minutes. Integrity testing can be performed before and after use, and it is resistant to multiple cleaning cycles. This filter also has the capability to capture bacteria. 【Features】 ■ Uses a PTFE membrane with a pore size of 0.2 μm ■ Unsterilized type ■ Can be autoclaved at 121-123°C for up to 20 minutes ■ Equipped with bacteria capture functionality *For more details, please refer to the PDF document or feel free to contact us.

The "Acro 50 Vent Filter" is designed as a bacterial air vent for the sterilization of air and gases, as well as for pharmaceutical research and experimental processes. The filter's pore sizes are available in three options: 0.2, 0.45, and 1 μm. Additionally, we offer the "Acro 50 Bend Device (Enflon II PVDF Membrane)" which has a removal rate of 0.2 μm in liquids and can remove particles smaller than 0.02 μm in air/gas applications. 【Features of PTFE Membrane】 ■ The filter's pore sizes are available in three options: 0.2, 0.45, and 1 μm ■ Non-sterile type that can be sterilized by autoclaving ■ Integrity testing can be performed before and after use ■ Filters are available with hose barb, 1/8 inch MNPT, and 3/8 inch straight pipe options *For more details, please refer to the PDF document or feel free to contact us.

This product is designed for filtration of bioreactors and chemicals or solvents that require a large effective filtration area (280 cm²) and high airflow. It is possible to perform autoclave sterilization and integrity testing before and after use. It features a high level of hydrophobicity and guarantees excellent performance as an aseptic barrier, with membranes made of PTFE or PVDF available. The bacteria air vent uses a laminated membrane made of fiberglass that can be used at high temperatures, high pressures, and high flow rates. 【Features】 ■ Large effective filtration area (280 cm²) ■ Autoclave sterilization capability ■ Integrity testing before and after use ■ Designed for filtration of bioreactors and chemicals or solvents *For more details, please refer to the PDF document or feel free to contact us.

The integrity test kit includes a pressure gauge, a three-way valve, and a 10 mL syringe. It is possible to test the integrity of filter products after autoclave sterilization. It can be used for water breakthrough tests and bubble point tests. We also offer a variety of filter sizes, materials, and pore sizes to meet your specific applications. 【Features】 ■ It is possible to test the integrity of filter products after autoclave sterilization. ■ Usable for water breakthrough tests and bubble point tests. *For more details, please refer to the PDF document or feel free to contact us.

We would like to introduce our "0.2 μm PSF Acrodisc Syringe Filter." The free-floating pre-filter prevents early clogging. The thermally bonded 0.2 μm final membrane guarantees particle removal without breakthrough. 【Features】 ■ Wide range of product lineup (GHP, PVDF, PES, Nylon, PTFE) ■ Enhanced filtration efficiency with multi-pre-filter (GxF) ■ Compatibility guarantee for SOTAX automatic analyzers for dissolution testing ■ Low drug adsorption and low elution performance ■ Effective filtration area of 3.9 cm² in 25 mm size *For more details, please refer to the PDF document or feel free to contact us.

We would like to introduce the "0.45 μm PSF Acrodisc Syringe Filter" for HPLC and IC handled by Nippon Paul Co., Ltd. The filtration efficiency is improved by the multi-prefilter (GxF), allowing for a filtration volume that is 2 to 4 times greater than that of standard glass fiber products. Additionally, it has high pressure resistance, eliminating concerns about housing breakage during use. 【Features】 ■ Wide range of product lineup - HPLC guaranteed: GHP, PVDF, Nylon, PTFE - IC guaranteed: Supor (PES) ■ Column protection ■ Low drug adsorption and low elution performance *For more details, please refer to the PDF document or feel free to contact us.

We offer membrane disc filters that are optimal for filtering mobile phase solvents in HPLC. - wwPTFE (highly hydrophilic PTFE) membrane: A highly versatile filter that can be used for aqueous and organic solvents. It has excellent chemical resistance and can handle strong organic solvents, making it ideal for filtering mobile phase solvents in HPLC. - Nylaflo (nylon) membrane: A hydrophilic membrane with excellent chemical compatibility for esters, alkalis, and alcohols (however, it cannot be used with solvents containing acids of 1N or higher, or halogenated compounds). - PTFE membrane: Exhibits outstanding chemical compatibility for filtering strong organic solvents. These membranes can be used in combination with Solback filter holders suitable for filtering mobile phase solvents.

The Acrodisc WBC syringe filter uses unique filter technology to separate white blood cells from 10 mL of whole blood in less than 10 minutes. This syringe filter contains Leukosorb media, which has two properties: size exclusion and adsorption. It captures and collects white blood cells from whole blood samples while allowing red blood cells and platelets to pass through the membrane with its fibrous matrix.

The Acro 500 is a filter capsule equipped with a Supor EKV membrane and a polycarbonate housing, featuring an effective filtration area of 500 cm², allowing for the filtration and sterilization of large volumes of solutions. This capsule incorporates a dual-layer membrane made of polyethersulfone (PES), enabling high-flow filtration. This membrane has low binding characteristics for proteins and preservatives, allowing for maximum permeability of the target components. Additionally, it is compatible with a wide range of solvents, making it suitable for filtration in various applications such as buffers and culture media. The polycarbonate outer housing has improved optical clarity, facilitating easy venting of the capsule during use and maximizing membrane area and flow rate.