同仁グローカル List of Products and Services

I would like to introduce "sugar analysis." Sugars are one of the main biological components in plants and animals, ranging from simple sugars known as monosaccharides to oligosaccharides and polysaccharides, which are high molecular weight sugars formed by the combination of multiple monosaccharides. There are methods to measure the quantity of these sugars using enzymes and high-performance liquid chromatography (HPLC). [Analysis Examples] ■ Sugars contained in experimental samples: culture media, biological samples (serum, tissues, etc.) ■ Sugars contained in solid waste, extraction residues, etc. ■ Sugars contained in enzyme treatment solutions, microbial treatment solutions, etc. *For more details, please refer to the PDF document or feel free to contact us.

I would like to introduce "color difference analysis." Color is perceived by the human eye as light emitted from an object, and that signal is processed by the brain to be recognized as color. Therefore, if the light emitted from an object is reflected light, it is captured as color. The reason a lemon appears yellow is that the substances on the surface of the lemon absorb light in the visible spectrum that is not within the wavelengths that humans can perceive as yellow. [Analysis Examples] ■ Drinking water, environmental water, dye solutions, and other liquids ■ Chemicals, pharmaceuticals, powders, pastes, and other solids *For more details, please refer to the PDF materials or feel free to contact us.

I would like to introduce "cell assays." For example, they are commonly used to quantify the toxicity of drugs to cells or to evaluate the toxicity and proliferation activity of new compounds. In research applications, they are also utilized for visualizing organelles within cells and analyzing cell dynamics using time-lapse techniques. 【Analysis Examples】 ■ Measurement of IC50 values of test substances using the WST method (cytotoxicity) ■ Measurement of proliferation activity of test substances using the WST method ■ Time-lapse analysis *For more details, please refer to the PDF materials or feel free to contact us.

This article introduces fatty acid analysis. When hearing about lipids, many may associate them with fat accumulation in the body, leading to weight gain and obesity. Additionally, many might also think of conditions such as arteriosclerosis and cardiovascular disorders. Some may recall triglyceride levels, which is one of the lipid metabolism items in health check-ups. *For more detailed information, please refer to the related links and catalog. Feel free to contact us for further inquiries.*

This article introduces methods for analyzing fatty acids. Including ourselves, living organisms on Earth are composed mainly of water, proteins, nucleic acids, carbohydrates, lipids, electrolytes, and so on. These components can be analyzed in various ways. If a protein is an enzyme, its activity can be evaluated by reacting it with a substance called a substrate and measuring the amount of the substance converted by the enzyme. *For detailed content of the article, please refer to the related links and catalog. For more information, feel free to contact us.

Living organisms are collections of cells, and cells are separated from the internal and external environments by membranes made of lipid molecules. These membranes include the cell membrane that shapes the cell and the organelle membranes that form intracellular organelles. Various reactions occur throughout the separated areas as the outside and inside are connected through these membranes. Additionally, lipids play an important role in energy storage and production. Here, we summarize the structure of lipids, the energy production process of fatty acids, the biosynthetic pathways of fatty acids, the flow of lipid synthesis, and methods for measuring fatty acids. *For detailed content of the article, please refer to the related links and catalog. For more information, feel free to contact us.*

This article introduces methods for evaluating cell activity. The ability to use cells in experiments is largely due to advancements in cell culture techniques and the establishment of cell lines, which are the results of research conducted from the early to mid-20th century. The culture medium began with isotonic solutions (physiological saline, 0.9 w/v% sodium chloride solution), followed by the development of Ringer's solution, the use of serum-supplemented media, and the detachment of adherent cells using trypsin. Additionally, the immortalized animal cell line L929, derived from mouse fibroblasts, was reported around the mid-20th century, and shortly thereafter, the human cell line HeLa was established. *For more detailed information, please refer to the related links and catalog. Feel free to contact us for further inquiries.*

We perform methylation, oximation, and trimethylsilylation reactions on samples to derivatize them for GC/MS analysis. By comprehensively analyzing low molecular weight metabolites such as sugars, amino acids, fatty acids, and polyphenols in food, it is possible to clarify the state and characteristics of the food. Additionally, by simultaneously detecting and comparing numerous components, we can identify differences between samples. This allows for efficient verification of materials and processing methods. 【Metabolite Analysis in Food】 ■ Monitoring of specific metabolites using standard compounds (target analysis) ■ Monitoring of detectable metabolites (non-target analysis) ■ Other analytical proposals based on requests *For more details, please download the PDF or feel free to contact us.