日本ウォーターズ（米国本社 Waters Corporation）　 List of Products and Services

To enable systematic analysis of fluorescently labeled N-glycans isolated from recombinant biopharmaceuticals using HILIC-UPLC(R). The data will be analyzed using a robust online glycan database that utilizes standardized retention times. 【Features】 ○ Structures including monosaccharide sequences, stereochemistry, and linkage types displayed in color or black and white diagrams → Linkage types represented in Oxford notation and CFG notation ○ GU retention time values and descriptive quality statistics For more details, please contact us or download the catalog.

Empower 3 Chromatography Data Software (CDS) is a system that meets the demands of networking and enables more efficient data acquisition, management, analysis, and reporting. Empower makes it easy to meet requirements for data integrity. Empower provides the highest level of data integrity and traceability for all raw data, metadata, and result data.

From standard samples and reagents to separation columns, vials, LC, MS, and software for data analysis, Waters provides comprehensive support for our customers' inquiries. Waters' latest innovations in LC and LC/MS, particularly focused on biopharmaceuticals, are designed to address needs related to applications, the challenges posed by a large number of compounds, and regulatory compliance requirements that trouble development labs. Waters' solutions are adopted by leading companies worldwide, helping to obtain faster and more accurate answers regarding the characteristics and quality of biopharmaceuticals.

■ Streamlining the creation of free workflow documents in the lab ■ Improving work efficiency in accordance with process-driven SOPs ■ Search function: Querying single or multiple databases to search for data (*1) ■ Access to information Data from analytical instruments can be centrally managed in NuGenesis, allowing for automatic import of information from the data into ELN documents for utilization. It is also possible to integrate information managed by other software (*2). ■ Integration with other information systems NuGenesis ELN provides an open interface to other information systems (*3). ■ Security, intellectual property protection, compliance The NuGenesis lab management system is designed to comply with regulations and includes a certificate of structural integrity to support users in regulated environments. For details on *1, *2, and *3, please check the Waters website.

The "NuGenesis SDMS System" is an automated data repository (storage) that serves as the foundation for the NuGenesis laboratory management system. NuGenesis automatically imports various data from the lab into a centralized data repository. Information can be searched and communicated immediately, making it easy to share among researchers and team members. 【Features】 ■ Acquire and archive data ■ Search, retrieve, and reuse information ■ Integrated Paradigm scientific information search system software ■ Electronic sharing of information ■ Seamless integration with existing systems ■ Vendor-independent display of analytical data *For more details, please refer to the PDF materials or feel free to contact us.

By implementing the Empower server system, it is possible to use Empower from home or while on business trips. • Empower can directly control not only our company's chromatographs (LC/GC) but also those from other manufacturers, enabling centralized management of chromatographic data. • It can be used without installing Empower on each terminal (also on laptops, tablets, and smartphones). • All operations of Empower, including analysis interruptions and re-injections, are possible. • You can carry out your work smoothly using the electronic approval function. * A terminal server with Citrix's XenApp installed is required. If you are interested, please feel free to contact us using the inquiry form below.

The smart LIMS proposed by Waters is a next-generation LIMS that adds important features not found in traditional LIMS, such as raw data management, reagent and equipment management, and the utilization of existing resources. 1. Management of Raw Data It integrates and centrally manages analytical instrument data in various formats and electronic documents. It is also possible to automatically retrieve raw data files from analytical instruments. 2. Reagent Management and Equipment Management Reagent Management - Manages information such as reagent name, lot number, potency, expiration date, manufacturer, usage logs, and links to records that used the reagent. - Supports the issuance of barcode labels. Equipment Management Manages information such as equipment name, manufacturer, serial number, expiration date, calibration date, and regular inspection date, as well as usage logs and links to records that used the equipment. 3. Utilization of Existing Resources - Allows the creation of laboratory notebooks, templating, and data storage using office applications. For example, it can directly import records created in Excel (or through drag & drop). - Existing files can be templated as parts of records, reducing the development time for templates.

Companies dealing with cosmetics and personal care products must continuously launch innovative products in a very short period to achieve growth and profitability goals in a fiercely competitive market. At the same time, they are required to address many challenges, such as responding to increasing demands from regulatory authorities, analyzing complex samples, ensuring product safety and efficacy, and countering the threat of counterfeit goods.

The networking of Chromatography Data Systems (CDS) is progressing, and recently there has been an active shift from on-premises to off-premises solutions, including cloud-based infrastructures. On the other hand, the damage caused by natural disasters and human-made disasters such as cyberattacks is becoming increasingly severe and frequent, necessitating countermeasures. BC LAC/E will address these needs as a new lineup of LAC/E32 within the Empower 3 network system. In cases where communication between the lab and the Empower 3 database server is interrupted for an extended period, BC LAC/E can be switched to a standalone system of Empower 3, allowing for the immediate recovery of chromatography analysis operations even after a disaster. The data necessary for analysis (various methods, user information, etc.) is always synchronized within BC LAC/E, ensuring smooth recovery even in unexpected situations.

1. Centralized management of all measurement data NuGenesis SDMS connects with various measuring instruments present in the laboratory and collects all data generated by these instruments. It can connect regardless of the type or manufacturer of the measuring instruments. 2. Centralized management of all records and reports NuGenesis SDMS also collects reports created in tools like Microsoft Excel. 3. Access to data Data collected in NuGenesis SDMS can be accessed from anywhere according to user permissions. It also features electronic approval functionality. 4. Flexible search functions and data utilization NuGenesis SDMS allows searches using various methods such as text, structural formulas, and spectra. Quickly reaching the necessary information leads to effective data utilization. 5. Complete logging Data is logged (audit trail) with information on when and by whom it was generated, which helps in protecting intellectual property.

General benefits of digitizing experimental records: - Data can be shared within the organization and accessed from anywhere. - The search function significantly reduces the time spent looking for necessary data. - The utilization of data is promoted. Additional benefits with NuGenesis LMS: 1. Microsoft Excel, Word, etc., can be used within NuGenesis LMS. Functions and macros can be used as they are in Excel. Existing records and reports can be utilized. 2. Centralized management of all measurement data. Measurement data is collected and managed by connecting various measuring instruments present in the laboratory. It can connect regardless of the type or manufacturer of the measuring instruments. Data from measuring instruments is linked to experimental records. 3. Complete logging of records. Logs (audit trails) are recorded with the data, managing information such as when and by whom it was generated. This helps in protecting intellectual property. 4. Accumulating experimental records for further utilization. By linking the accumulated data with higher-level systems, it contributes to the promotion of digital transformation (DX).

When the person planning the testing operations is different from the one executing them, or when multiple people are involved, managing a series of flows on paper can be cumbersome and time-consuming when dealing with issues. NuGenesis LMS addresses these challenges by integrating and managing information across all phases of the testing operations that proceed through the following flow: 1. Request for Testing Register samples and set necessary tests, responsible personnel, deadlines, etc. Once the settings are complete, sample labels and test instructions are automatically generated. The status of samples and tests can be checked in real-time. ↓ 2. Conducting Tests and Automatic Input of Results The test personnel conduct the tests based on the test instructions. Test results are directly input from measuring instruments via network or electronic media. ↓ 3. Evaluation of Results Individual results are evaluated against pre-set standards. ↓ 4. Approval of Results The scope of operations can be limited based on permissions set for each user, and approvals are also conducted based on these permissions. ↓ 5. Issuance of Reports Once the results are approved, reports are automatically generated. Forwarding to email is also possible.

1. Centralized management of all measurement data NuGenesis SDMS connects with various measuring instruments present in laboratories and collects all data generated by these instruments, standardizing it into a machine-readable format. It can connect regardless of the type or manufacturer of the measuring instruments. 2. Extracting desired information from collected data and outputting files When NuGenesis SDMS collects data from measuring instruments, it automatically extracts the desired information based on the settings and outputs a text file. If upper systems like LIMS can automatically read this file, a mechanism can be established to automatically transfer measurement data to the upper system. 3. Data is securely stored Data collected in NuGenesis SDMS has access restricted by user. Logs (audit trails) are recorded, and overwriting or deletion is not permitted. 4. Flexible search functionality and electronic approval feature NuGenesis SDMS is equipped with various search methods, allowing instant access to the necessary information. It also includes an electronic approval feature.

In recent years, "functional ingredients" that add value to food have gained attention, and various foods containing these functional ingredients are being developed, manufactured, and sold as Foods for Specified Health Uses (Tokuho) and Foods with Functional Claims. However, in the analysis of functional ingredients contained in food, achieving excellent separation and high sensitivity detection using liquid chromatography (LC) often poses challenges, making it difficult to objectively evaluate flavor components that affect taste. Waters, as a specialized manufacturer of LC and mass spectrometers, supports reliable analysis of functional claim foods with high-sensitivity mass spectrometers, as well as total solutions including LC systems, columns, and informatics that achieve high separation. ★ Application notes and on-demand webinars are now available We are currently offering application notes and various materials related to reliable routine analysis of functional ingredients and flavor components. Please check them out under "Download."