日本ウォーターズ（米国本社 Waters Corporation）　 List of Products and Services

PFAS have excellent chemical properties such as water and oil repellency and surfactant characteristics, and are used in a wide range of fields. On the other hand, due to their persistence and bioaccumulation, numerous cases of PFAS detection in water quality, the environment, and food have been reported both domestically and internationally. As a result, countries are advancing regulations and monitoring efforts, and there is a demand for more sensitive and accurate measurement technologies. In Japan, a ministerial ordinance was announced to raise the water quality standards for "PFOS" and "PFOA," which will take effect in April 2026. Waters is focusing on the development of methods for analyzing PFAS in trace amounts in various samples. In addition to providing analytical instruments, we also offer insights on sample preparation and blank contamination prevention, as well as service and support for the instruments, along with consulting services tailored to analytical needs. By clicking [Send], you agree that the information provided on this site will be used and processed by Waters in accordance with the Waters Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy

PFAS has excellent chemical properties such as water and oil repellency and surfactant characteristics, and is used in a wide range of fields. On the other hand, due to its persistence and bioaccumulation, numerous cases of PFAS detection in water quality, the environment, and food have been reported both domestically and internationally. As a result, countries are advancing regulations and monitoring efforts, and there is a demand for more sensitive and accurate measurement technologies. In Japan, a ministerial ordinance was announced to raise the water quality standards for "PFOS" and "PFOA," which will take effect in April 2026. Waters is focusing on developing methods for trace analysis of PFAS in various samples. In addition to providing analytical instruments, we offer insights on sample preparation and blank contamination prevention, as well as equipment service and support, along with consulting services tailored to analytical needs. By clicking [Send], you are deemed to have agreed that Waters will use and process the information provided on this site in accordance with the Waters Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy

【Features】 ○ Reverse phase solid-phase filler ○ Conditioning and equilibration can be omitted due to water-wettable filler ○ Significantly reduces matrix effects that influence ionization, especially during MS detection ○ High recovery rates and reproducibility for a wide range of analytes ○ Minimal clogging, allowing for use at lower suction pressures and with less applied pressure ○ Maximizes the removal efficiency of lipids and phospholipids

This is a low-adsorption column that employs MaxPeak HPS technology, which minimizes the interaction between the analyte and column hardware (column tube) that can cause sample loss, thereby improving the recovery rate, sensitivity, and reproducibility of the analyte. MaxPeak HPS technology is an advanced surface treatment technology rather than a resin coating. It is designed to withstand the rigorous conditions of high-throughput laboratories, providing excellent performance that lasts without compromise. 【Features】 - Reduces the effort and time required for column conditioning and passivation - Improves sensitivity and peak shape - Allows analysis with a simpler mobile phase that does not contain complex additives - Saves time in method development - Reduces risk and enhances reliability in data and decision-making - A lineup compatible with all LC systems including UPLC/UHPLC/HPLC

The Waters GTxResolve Premier SEC column enables superior and faster separations by minimizing particle size to the extreme. Additionally, the new HO-PEO bonding reduces both ionic and hydrophobic adsorption, and the stable bonding also achieves noise reduction in MALS. The column tube is treated with MaxPeak technology, eliminating concerns about metal adsorption. 【Features】 - High separation capability allows for the detection of low-concentration impurities, accelerating the analysis of aggregates and size variants. - Provides reproducible data with minimal lot-to-lot and column-to-column variation. - Cost reduction through extended column lifespan. - Reduces secondary interactions and decreases noise in multi-angle light scattering detectors (MALS). - Utilizes low-adsorption hardware necessary for improving the recovery rate of biopharmaceuticals.

This is the latest high-performance LC column family that maximizes the performance of laboratory LC systems. With high column efficiency, it achieves superior throughput and high separation compared to fully porous particle columns. It offers 1.6μm for UPLC, which realizes the ultimate theoretical plate count, and 2.7μm for HPLC/UHPLC, which is practical with low back pressure, allowing you to choose the optimal column for each analysis from a total of seven types of chemistry. Whether you want to separate complex samples or maintain separation while improving throughput, it delivers results beyond expectations. 【Features】 - Adoption of solid-core (core-shell) particles to maximize column efficiency - Particle size of 1.6μm for UPLC separation and 2.7μm for UHPLC/HPLC separation - A chemistry lineup that broadens selectivity for method development - Seven types of chemistry lineup: C18, C18+, T3, C8, Shield RP18, Phenyl, HILIC - Easy and seamless transfer of methods between 1.6μm and 2.7μm - Excellent reproducibility between batches and columns through comprehensive management of the entire manufacturing process from particle synthesis to final product

Many of the LC columns currently available on the market cannot fully leverage the benefits derived from the performance of the latest UHPLC systems. Waters offers a variety of columns for UHPLC, such as CORTECS columns and eXtended Performance [XP] columns, to assist customers in overcoming challenges in their analyses. This expands the options for column selection and maximizes the potential of analytical laboratories. **Features** - CORTECS 2.7μm columns that utilize solid-core (core-shell) particles to maximize UHPLC separation performance - XP columns that use three types of particle substrates: ethylene-bridged hybrid (BEH), High Strength Silica (HSS), and Charged Surface Hybrid (CSH), providing excellent selectivity and flexibility in method development - Column sizes and particle diameters designed for UHPLC - Seamless method transfer between UPLC, UHPLC, and HPLC - Exceptional reproducibility between batches and columns through comprehensive management of the entire manufacturing process from silica and hybrid synthesis to the final product

Waters is developing a business based on chromatography. It is our customers who utilize this chromatography technology in their businesses. The innovative insights in your labs lead to the establishment of analytical/testing methods that contribute to business success. Our customers' "success" can be evaluated by continuously monitoring analytical methods and results, and it is essential that the chosen columns remain available for you to continue achieving "success" in the future. Many customers who fully understand the impact of column performance and innovation on "success" have chosen Waters' cutting-edge reversed-phase and HILIC HPLC column products. 【Features】 - Synthesis of silica and hybrid materials conducted in-house: Latest technology can be applied to particles. - All latest chromatography packing materials are consistently managed from starting monomers to final products. - Manufacturing facilities are certified cGMP, ISO9001, and ISO13485: Establishing analytical reliability through stringent quality control systems. - Most column hardware is also manufactured in-house from raw materials. - As a global company, we provide products of the same quality in countries around the world.

The ACQUITY APC column provides advanced packing technology for the separation of complex synthetic polymers and macromolecular species, delivering superior performance and reliability for high-resolution polymer characterization compared to conventional GPC columns. The ACQUITY APC column further enhances Advanced Polymer Chromatography as follows.

Companies dealing with cosmetics and personal care products must continuously launch innovative products in a very short period to achieve growth and profitability goals in a fiercely competitive market. At the same time, they are required to address many challenges, such as responding to increasing demands from regulatory authorities, analyzing complex samples, ensuring product safety and efficacy, and countering the threat of counterfeit goods.

Glycosylation of proteins is a very important post-translational modification that regulates both the structure and function of proteins. Changes in glycan profiles can affect drug efficacy and immunogenicity, so glycosylated biopharmaceuticals require thorough characterization. In the characterization of glycoproteins, the wide-pore HILIC amide column (Glycoprotein BEH Amide, 300Å), which provides complementary information with reverse phase columns, allows for the separation of intact glycoproteins, glycoprotein subunits, or at the glycopeptide level based on the number and composition of glycans, enabling the acquisition of unprecedented glycoform information.

With UPLC technology, you can invest in the future by having the robustness and reliability to perform existing HPLC analytical methods within a single system, while optimally operating UPLC columns with particle sizes of 2 μm or less. The ACQUITY UPLC(R) system family serves as a platform for LC technology that can be utilized regardless of separation requirements, making it easy to enhance productivity and facilitate method transfer between facilities. 【Features】 - Six types of UPLC particles based on ethylene-bridged hybrid, High Strength Silica, and Charged Surface Hybrid - 22 types of stationary phases - Seven types of application-specific chemistries - Designed to seamlessly deliver performance with the ultra-low dispersion ACQUITY UPLC system - Over 200 options (column sizes and chemistries) available to select the optimal column that balances separation capability and throughput For more details, please contact us or download the catalog. *The catalog will be a digest version. If you need the full version, please contact us.

We will demonstrate the advancements in size exclusion separation based on UPLC using data analyzed from polymer protein complexes, comparing it with HPLC data. Additionally, we will analyze monoclonal antibodies containing multivalent aggregates by connecting ACQUITY UPLC BEH SEC columns with pore sizes of 200 Å and 450 Å, showcasing the benefits obtained. 【Application Benefits】 ○ Compared to conventional HPLC-based SEC, improved separation of high molecular weight proteins up to 1.8 MDa. ○ In the analysis of monoclonal antibody aggregates containing dimers and higher-order multimers, the separation range is expanded by connecting the BEH450 SEC column with the BEH200 SEC column. For more details, please contact us or download the catalog.

Peptide mapping using formic acid instead of TFA enables more sensitive detection with ESI-MS. The CSH130 C18 shows outstanding performance regardless of the acidic modifier used, making it ideal for LC/MS-based peptide mapping. In LC/MS analysis using a formic acid mobile phase for enolase tryptic digest, the CSH130 C18, 1.7μm column achieved a 30% higher peak capacity compared to common fully porous or superficially porous C18 columns of the same particle size. Furthermore, analysis results of high molecular weight peptides and low molecular weight proteins demonstrated that the CSH130 C18 column with a pore size of 130Å is suitable for the separation of polypeptides up to approximately 10 kDa in molecular weight. 【Application Benefits】 - High peak capacity and unique selectivity compared to other C18 columns - Compatibility with formic acid and ESI-MS - High separation ability for analytes up to approximately 10 kDa - CSH130 C18 has been QC tested with cytochrome c tryptic digest For more details, please contact us or download the catalog.

The Glycan Performance Test Standard is labeled with human-type IgG using 2-AB. It has been verified that it contains two important glycans, Man-5 and Man-6, which are not necessarily present in human IgG. Man-5 is particularly important for confirming separation. If these glycans need to be added, it has been verified that the Glycan Performance Test Standard always contains Man-5 and Man-6. 【Features】 ○ Stable freeze-dried product ○ Immediately usable after dissolving in a 50-70% acetonitrile aqueous solution ○ Specially designed considering important criteria for column quality control used in quality management at Waters Corporation's column manufacturing facility For more details, please contact us or download the catalog.

Waters' product development begins with a deep understanding of the challenges related to biomolecules that you are currently facing. We support a wide range of bioseparation with an extensive column lineup to solve various challenges such as sensitivity, separation, selectivity, and load capacity, from reversed phase and HILIC to SEC and ion exchange. Additionally, we provide reliable and high-quality products, from sample preparation products for biomolecules to reagents. For more details, please contact us or download the catalog.

The analysis of proteins with high molecular weight and complex structures is accompanied by many difficulties. Waters has developed a new reversed-phase column based on the feedback and requests from researchers and analysts who are actually working on protein analysis. The BioResolve RP mAb Polyphenyl column uses solid core particles with a particle size of 2.7 μm and incorporates novel functional groups, achieving not only improved separation but also significant improvements in carryover compared to low molecular weight compounds. At the same time, it reduces issues commonly associated with high temperatures and ion-pair reagents used in reversed-phase separation of proteins. Additionally, we offer guard columns and standards specifically designed for protein analysis, along with comprehensive support such as user-friendly procedures and analysis examples for those conducting protein analysis for the first time.

Glycoprotein analysis requires the identification of complex N-linked and O-linked structures consisting of repetitive similar sugar components. Hydrophilic interaction chromatography (HILIC) utilizing fluorescence detection is a highly reliable analytical method that effectively separates and quantifies glycan chains labeled with fluorescent labeling reagents. The Waters Glycan Separation Technology column is a dedicated QC-tested column developed for the rapid analysis of various glycan structures with excellent UPLC(R) separation capability. By combining the Waters ACQUITY UPLC(R) system with column chemistry, accurate analytical results can be obtained more quickly. 【Features】 ○ Shorter time and higher separation capability compared to conventional HPLC methods ○ Ideal for use with the ACQUITY UPLC fluorescence detection system ○ Stable and reproducible separation of labeled glycan chains Waters BEH particles and functional group bonding technology ○ QC tests using labeled glycan standards are conducted to ensure consistent column performance between batches For more details, please contact us or download the catalog.