サーモフィッシャーサイエンティフィック株式会社／Thermo Fisher Scientific K.K. List of Products and Services

The Thermo Scientific CellInsight CX7 LZR HCS Platform is a high-speed laser-based automated cell imaging device. It provides the sensitivity and speed required for advanced assays. The powerful laser light source and confocal optical system enable 3D imaging even in thick samples. It offers quantitative imaging and image analysis techniques for various cell analyses, including compound screening, cytotoxicity testing, and fundamental biology. Features: - Multi-color analysis is possible with near-infrared (785nm) laser excitation. - Utilizes cost-effective lasers. - Compatible with various plate formats, not just 96-well plates. - High-sensitivity detection systems and laser autofocus capabilities speed up image acquisition. *For more details, please refer to the PDF document or feel free to contact us.*

The Thermo Scientific CellInsight CX5 HCS Platform is a compact cell image analyzer that meets personal needs with easy operation for image acquisition and analysis. It is equipped with 37 types of assay templates that cater to various applications. It enables quantitative and objective cell analysis through high-content analysis (HCA) and high-content screening (HCS). Features: - Supports various samples with 5-color LED and transmitted light functionality - Equipped with a large-format X1 camera, capable of processing many samples at once - Suitable for a wide range of applications including regenerative medicine research, drug discovery, and toxicity studies - Allows for easy image acquisition and analysis - Compatible with automation systems *For more details, please refer to the PDF materials or feel free to contact us.

Invitrogen Attune Flow Cytometers were developed to eliminate the barriers of traditional flow cytometry and enhance new scientific possibilities. They are equipped with improved sample processing speed and throughput, provide high-precision data, and have resistance to clogging, which has been a problem with conventional flow cytometers. Models equipped with high-speed cameras can simultaneously capture fluorescent signals and bright field images. Features: ■ Achieves excellent data reproducibility and stability ■ Maintains low data coefficient of variation even in highly diluted or concentrated samples ■ Maintains consistent concentration across all flow rates With the addition of image data... ■ Further characterization based on the morphological features of cell populations becomes possible. ■ Data analysis gains reliability and depth. ■ The accuracy of gating improves, eliminating variability among users. *For more details, please refer to the PDF materials or feel free to contact us.

The Invitrogen EVOS M5000 Imaging System is a fluorescence microscope equipped with high resolution and versatile features. It includes a high-resolution camera, a bright digitally controlled LED light source, and intuitive software, enabling high-quality fluorescence and color imaging with great flexibility. Following seamless image acquisition, it offers a convenient toolkit for analyzing, editing, and annotating images that can be used in live mode or with saved images. Features: - Automatic cell counting and confluence measurement with onboard software - All-in-one microscope that does not require a darkroom or looking through lenses - Multi-channel automatic fluorescence imaging - Equipped with a high-resolution monochrome camera - Access to images and data anytime, anywhere via the Thermo Fisher Cloud Platform - Can be installed in a safety cabinet for clean operation *For more details, please refer to the PDF document or feel free to contact us.

The Invitrogen EVOS M7000 Imaging System is a fluorescence microscope that meets the demands of advanced imaging analysis, including live cell imaging, time-lapse, image tiling, and Z-stack imaging. It integrates all the workstation functions of a digital inverted microscope into a compact size, allowing for intuitive operation and versatile imaging. A powerful PC equipped with a GPU that supports high-speed processing and large-scale data provides a robust image processing environment. Features: ■ High image quality ■ Improved throughput and data quality ■ Flexibility to meet a wide range of needs ■ Simultaneous acquisition of multiple images ■ Provides a powerful image processing environment *For more details, please refer to the PDF document or feel free to contact us.

The Invitrogen Countess 3 / 3 FL Automated Cell Counter automatically adjusts focus and counts cells when a slide is inserted. Equipped with a deep learning analysis algorithm, it enhances the recognition and identification accuracy of cells. This improves the accuracy and precision of cell counts for small cells such as peripheral blood mononuclear cells (PBMC) and cell aggregates. Features: - Enhanced analysis algorithm for improved accuracy and precision - Automation of data saving with auto-focus functionality - Automatic reporting of histograms and SCF files - Compatible with reusable glass slides - Fluorescence measurement can also be added* - Supports cloud analysis tool "Connect" and Wi-Fi *Countess 3 FL Automated Cell Counter *For more details, please refer to the PDF document or feel free to contact us.

The Invitrogen Qubit Flex Fluorometer is a fluorometer that can measure up to 8 samples simultaneously. By using an 8-tube setup for measurements, throughput is significantly improved. Additionally, the device has storage capable of holding data for up to 10,000 samples. Furthermore, it allows for easy data management through the cloud-based Connect Platform via USB or network connections. Features: - Simultaneous measurement of 8 samples - Smart data management - User-friendly and convenient software - Provides high-quality data with minimal measurement error - Includes a Wi-Fi adapter for smart data management *For more details, please refer to the PDF materials or feel free to contact us.

The Invitrogen Qubit 4 Fluorometer is a fluorometer that can perform everything from quantifying nucleic acids and proteins to checking the condition of RNA, all in one device. It quantifies using fluorescent reagents that bind to specific target molecules in the sample, allowing for accurate quantification even in samples containing impurities. It quickly and accurately quantifies and checks the condition of samples, which serves as the foundation for experiments, supporting improvements in experimental quality and efficiency. Features: ■ Check the risk of RNA degradation in just 5 minutes ■ Three functions in one device, from nucleic acid to protein quantification ■ Accurate even with samples containing impurities ■ Supports Japanese language ■ Excellent operability *For more details, please refer to the PDF document or feel free to contact us.

The "AAV Production Contract Service" is a service that produces the desired Adeno-Associated Virus (AAV) using the proven Gibco AAV-MAX Helper Free AAV Production System in a suspension culture system. Depending on the application, affinity purification using the Thermo Scientific POROS CaptureSelect series and various analyses (Titer measurement by quantitative PCR and evaluation by SDS-PAGE) are also possible. All work is conducted in a domestic lab, allowing us to deliver in the shortest possible time from inquiry to delivery. We will also promptly respond to inquiries about the progress status. 【Features】 ■ Provides functional AAV at high purity and high concentration ■ Achieves high titer with multiple serotypes *For more details, please refer to the PDF document or feel free to contact us.

The high-end model "Bigfoot Spectral Cell Sorter" enables both spectral analysis and conventional compensation. It allows sampling from 1.5 mL, 5 mL, and 15 mL tubes, equipped with automatic tube type identification and crash detection features. Automated 5-axis stream alignment and QC enhance usability and reduce variability from short to long durations. 【Features】 ■ Convenient storage space that helps organize lab space ■ Automatic mixing of sheath fluid and system cleaning without human intervention ■ Equipped with stirring and temperature control (4–37°C) functions ■ Built-in custom-designed Class II safety cabinet ■ Flexibly accommodates various cell sorting applications *For more details, please refer to the PDF document or feel free to contact us.

The "Invitrogen Click-iT product series" generates no byproducts from the reaction components, resulting in minimal damage to cells and allowing for analysis that maintains a more natural cellular state. The reaction specificity of azides and alkynes is high, and since azides and alkynes do not exist in living organisms, data with low background can be obtained. 【Product Lineup (Partial)】 ■ Click-iT Plus EdU Assay Kit (Cell Proliferation and Cell Cycle) ■ Click-iT 5-ethynyl-uridine (EU) Imaging Assay (Nascent RNA) ■ Click-iT Chemistry Reagents (Glycans, Lipids, Nascent Proteins) ■ Click-iT Nascent RNA Capture Kit (Isolation of Nascent RNA) *For more details, please refer to the PDF materials or feel free to contact us.

The Invitrogen EVOS M3000 Imaging System is an all-in-one microscope capable of capturing brightfield, phase contrast, color, and fluorescence images. It simplifies cell culture workflows using an innovative machine learning model and provides real-time notifications of cell confluency values. Additionally, the built-in CMOS camera ensures the acquisition of remarkably high-quality images and videos of cells. Features: ◆ Obtain cell confluency data in seconds: Built-in real-time image analysis tool ◆ No training required: Simple user interface with a touchscreen display ◆ Space-saving design: The smallest footprint among the Invitrogen EVOS imaging system series (can be installed in clean benches or safety cabinets) *For more details, please refer to the PDF document or feel free to contact us.

The Thermo Scientific Multiskan SkyHigh absorbance microplate reader is equipped with a robust and reliable monochromator, making it suitable for a variety of research and routine applications. Features: - Capable of measuring a wide wavelength range from 200 to 1,000 nm in 1 nm increments (for both endpoint and spectral measurements) - Supports a diverse range of applications including quantification of nucleic acids such as DNA and RNA, various protein quantifications, and ELISA - Compatible with 6/12/24/48/96/384 well plates (supports lids up to a height of 19.5 mm) - Built-in shaking function and incubator function with a temperature range of +2 to 45 °C - Supports 9 languages including Japanese and English, accessible via touch screen or PC

The Thermo Scientific Multiskan FC absorbance microplate reader is a robust and reliable filter-based device suitable for a variety of research and routine applications. Features: ■ Supports a wide range of applications across wavelengths from 340 to 850 nm ■ Wide reading range of 0 to 6.0 Abs, with linearity up to 3.0 Abs ■ Measures 96-well plates in under 7 seconds ■ Large color LCD display and intuitive user interface ■ Stable performance with self-diagnostic capabilities ■ Can accommodate up to 8 filters (comes standard with 3 filters at 405 nm, 450 nm, and 620 nm) ■ Operable and analyzable from the device itself or standard software ■ Multi-language operation including Japanese and English ■ Ideal for ELISA and protein quantification

The Thermo Scientific Varioskan LUX Multi-Mode Microplate Reader is a device designed for bioscience research that requires support for a wide range of assays. Its automatic dynamic range selection feature simplifies measurement setup, and its smart safety controls help avoid experimental errors. Reliable results can be obtained quickly, even for applications that are difficult to measure. Features: ■ Five detection modes: absorbance, fluorescence, luminescence, TRF, and AlphaScreen ■ Equipped with a quad monochromator, it can accommodate a wide wavelength range ■ Optional gas module for controlling CO2 and O2 gases ■ Thermo Scientific SkanIt software for control and analysis supports nine languages, including Japanese and English ■ Capable of performing rapid dispensing and measurement simultaneously right after the start (when equipped with a dispenser) *For more details, please refer to the PDF document or feel free to contact us.

Invitrogen Celleste 6 Image Analysis Software is an image analysis software equipped with machine learning algorithms for advanced image analysis and quantification, including segmentation, counting, sizing, classification, and analysis. The MCA (Multi Class Analysis) tool, based on algorithms and analysis templates, allows for various analysis results such as heat maps, image montages, and histograms to be obtained in just a few steps. This powerful analysis software enables you to maximize the use of image data for processes such as neurite formation, angiogenesis, cell viability, and cell cycle. 【Examples of MCA Protocols】 ■Angiogenesis ■Autophagy ■Cell count ■Cell morphology ■Colocalization

The Invitrogen EVOS Onstage Incubator (OSI-2) is an incubator that can control temperature, humidity, and gas with high precision. It operates as a fully integrated unit with the Invitrogen EVOS M7000 Imaging System, enabling seamless live cell experiments, imaging, and analysis. It allows for the setting and saving of protocols along with microscope parameters on the same software as the EVOS M7000 Imaging System. Please contact us if you have any inquiries. 【Features】 ■ Fully integrated environmental chamber for live cell time-lapse imaging ■ High environmental control capability that can accurately maintain physiological or hypoxic conditions

The "Thermo Scientific KingFisher Apex Nucleic Acid, Protein, and Cell Automated Extraction and Purification System" is a device that rapidly processes purification applications using magnetic beads for DNA, RNA, proteins, and cells, providing highly reproducible results. With a touch screen and intuitive interface, it simplifies operation and reduces errors. It can be operated without a computer. Additionally, the software in the main unit allows for easy creation and editing of protocols, enabling customization of each step of the protocol, including the binding of magnetic beads to the purification target, washing, and elution. 【Features】 ■ Enhanced performance ■ Easy operation via touch screen ■ Customizable protocols ■ Capability to connect to cloud and network ■ Can simultaneously incorporate up to two types of magnetic heads and heat blocks, allowing selection from multiple formats based on the number of samples *For more details, please refer to the PDF document or feel free to contact us.

The "Thermo Scientific KingFisher PlasmidPro Maxi Processor" is a device that automates the purification of Maxi-scale plasmid DNA, eliminating the labor-intensive steps of centrifugation and pipetting. By simply placing 150 mL of E. coli culture (LB medium) into the cartridge, it enables the purification of endotoxin-free plasmid DNA (<0.1 EU/µg) within 75 minutes.

■ Equipped with highly versatile features It is equipped with high-performance functions such as autofocus, Z-stack functionality, and the ability to capture time-lapse videos. Additionally, it can record observation location information, allowing you to check on cells of interest at any time. ■ Smooth analysis with onboard software Based on machine learning, it performs measurements of confluency and automatic cell counting. ■ Diverse high-resolution images with a high-performance monochrome camera It can capture high-quality multi-color fluorescence images, and with a variety of LED light cubes, it is also possible to obtain color images using transmitted light.

The Invitrogen EVOS M3000 Imaging System is an all-in-one microscope capable of capturing brightfield, phase contrast, color, and fluorescence images. It simplifies cell culture workflows using innovative machine learning models and provides real-time notifications of cell confluency values. Additionally, the built-in CMOS camera accurately captures remarkably high-quality images and videos of cells. Features: ◆ Obtain cell confluency data in seconds: Built-in real-time image analysis tool ◆ No training required: Simple user interface with a touchscreen display ◆ Space-saving design: The smallest footprint among the Invitrogen EVOS Imaging System series (can be installed in clean benches or safety cabinets) *For more details, please refer to the PDF materials or feel free to contact us.