We will exhibit at BioJapan 2024.

Simultaneous measurement of 12 applications such as thermal stability, sizing, and viscosity from trace samples.

"Uncle" is a product that allows for the acquisition of more data with a small amount of protein. The required sample volume is only 9μL. By combining three different measurement modes—fluorescence, SLS, and DLS—it is easy to evaluate the optimal formulation and the stability of proteins or viral vectors. 【Features】 ■ Measure up to 48 samples in as little as about 2 hours with just 9μL. 【Applications】 ■ Tm & Tagg ■ Tm via SYPRO DSF ■ Isothermal stability ■ Sizing and polydispersity ■ Sizing via thermal gradient ■ Refolding measurements ■ Viscosity ■ kD ■ B22 ■ G22 ■ ΔG ■ Stability of viral capsids *For more details, please refer to the PDF document or feel free to contact us.

• Other protein analysis

It enables the monitoring of potency and purity throughout the entire workflow of lentivirus research and development, accelerating gene therapy development.

"Leprechaun" is a system that analyzes whether lentivirus particles are of the correct size and structure, and can measure viral titer. It allows for the determination of the titer of lentivirus present in a sample without being misled by confusing noise (such as incomplete viruses or contamination). Not only can it measure information that was previously only obtainable separately through conventional methods like ELISA, qPCR, and transduction assays, but it also enables structural analysis that those methods could not provide, all on a single platform. Capabilities: ■ Lentivirus titer ■ Lentivirus structure ■ Exosome concentration ■ Analysis of contamination (impurities such as extracellular vesicles) Features: ■ No sample purification required ■ Physical structural analysis possible ■ Distinction between virus integrity and impurities ■ Up to 16 samples can be measured at once *For more details, please refer to the PDF document or feel free to contact us.

• Other measurement and measuring equipment

Quality assessment of proteins, nucleic acids, AAV, LNP, etc. is possible with trace amounts and high throughput.

"Stunner" is a product that allows simultaneous acquisition of UV/Vis concentration, dynamic light scattering (DLS), and static light scattering (SLS) data from a 2μL identical sample. It enables detailed investigation of AAV and adenoviruses to measure total capsid titer and Empty/Full ratios, as well as to obtain payload concentration and size data of lipid nanoparticles all at once. You can analyze concentration, hydrodynamic size, polydispersity, and the presence of aggregates collectively, allowing you to assess the quality of proteins. This way, you can immediately determine whether your AAV, adenoviruses, lipid nanoparticles, or proteins are suitable for your purposes. [Features] ■ Measure up to 96 samples in a batch in 60 minutes*/12 minutes** *When measured by DLS **When measured by UV/Vis only [Applications] ■ AAV/Adenovirus capsid titer ■ AAV/Adenovirus Empty/Full ratio ■ Lipid nanoparticle (LNP) payload amount ■ Aggregate measurement ■ Concentration measurement ■ Sizing & polydispersity ■ B22 & kD *For more details, please refer to the PDF document or feel free to contact us.

• Other protein analysis

No complicated workflows needed! Only 2μL of sample volume required. Measure up to 96 samples in just 5 minutes.

"Lunatic" is a product that allows for easy simultaneous quantification of proteins, DNA, and RNA. The required sample volume is only 2μL, and up to 96 samples can be measured in 5 minutes. High-concentration samples can also be measured directly without dilution. 【Features】 ■ Measure 2μL, up to 96 samples in 5 minutes ■ Dynamic range coverage from 0.02 to 200 mg/mL* *for mAb ■ Outstanding accuracy and precision ■ Automation is also possible *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment
• Other protein analysis
• Other measurement and measuring equipment

Up to 8 samples can be processed simultaneously! Automatic and hassle-free buffer exchange and concentration that used to be complicated!

Buffer exchange and concentration must be performed as a sample preprocessing step. This is a labor-intensive task that takes a long time, requiring your presence throughout the process. "UNAGI" is a fully hands-free benchtop buffer exchange solution designed to take over this tedious task. It can process up to 8 samples simultaneously. The software is very easy to operate, allowing you to be anywhere during the work, eliminating the need to stay in the laboratory the entire time. 【Features】 ■ Simultaneous processing of up to 8 samples ■ Efficient solvent removal prevents sample adsorption, achieving over 96% recovery rate ■ Built-in recipes for UF/DF buffer exchange ■ User-friendly software ■ Concentrates up to 8 diluted samples from 48mL to 8mL in one go *For more details, please refer to the PDF document or feel free to contact us.

• Other Protein Research Software
• DNA analysis

You can measure 10 samples at once! There's no need to clean expensive chips that are prone to clogging!

"Honeybun" is a high-speed viscometer that can output data almost simultaneously with processing. Regardless of whether the number of samples is 1 or 10, it uses a few microliters of each sample through a microchannel and reads viscosities in the range of 0.5-150 cP within a few minutes. No pre-treatment or cleanup of samples is necessary. 【Features】 ■ Can measure up to 10 samples at once ■ Required sample volume: 35μL (can measure from 15μL; see application notes) ■ Measurement completed in under 1 minute (for viscosities below 10 cP) ■ Measurement range: 0.5-150 cP ■ No cleaning required and maintenance-free *For more details, please refer to the PDF document or feel free to contact us.

• Other bio-related products

Seamlessly transition from formulation condition screening to scale-up and GMP manufacturing. Accelerate LNP product development.

The development of lipid nanoparticles (LNPs) faces many challenges. The formulation, optimization, and scale-up for clinical trials are complex, costly, and a race against time. Our LNP solutions are designed to accelerate all steps of LNP synthesis and characterization. Sunscreen accelerates LNP formulation screening by reducing costs and time, generating up to 96 unique LNP formulations within 6 hours. Next, using Sunshine, you can develop, optimize, and scale up protocols with the appropriate formulations obtained from Sunscreen. When it comes to the clinical trial phase, Sunbather can accommodate LNP production in a GMP environment using the same processes and microfluidic chips (Sunny) utilized by Sunscreen and Sunshine. In this way, the Sun series allows for a seamless transition from screening formulation conditions to scale-up and GMP manufacturing, as they all use the same pumps and microchannel chips. *For product details, please download various materials.

• Other Physics and Chemistry Equipment

Accelerating formulation optimization for vaccine and pharmaceutical development.

The transition from LNP to GMP is a costly and complicated process. Typically, this requires switching equipment, using different flow paths and mixing devices, and essentially re-developing and re-validating everything that has been painstakingly done so far. With Sunbather, the transition to GMP can be done easily thanks to its recording features, interchangeable flow paths, and easily transferable design. Sunbather uses the same mixing process and protocols as the Sunscreen and Sunshine from the same Sun series, allowing for easy transition of adjusted formulation conditions to GMP. - Up to 1.8 L/h - Integrated inline dilution - Fully interchangeable flow paths - A wide variety of mixing devices - Software compliant with 21 CFR Part 11 - Process transferable from Sunshine

• Other Physics and Chemistry Equipment

Efficient mass production of LNPs - Supporting everything from small-scale condition testing to scale-up.

Once we succeed in finding the optimal formulation conditions for sunscreen, let's use Sunshine to adjust the size of the LNP. Furthermore, we will optimize the protocols and processes for scaling up. We will find the ideal flow rate and explore different mixing options. Next, we will adjust these to the appropriate dilution factor that can keep them stable. Once everything is in place, Sunshine will transition to continuous mode, allowing us to produce several dozen liters in a day. In other words, we will achieve process development and scaling up on a single platform. Many researchers have likely been looking forward to the birth of such a groundbreaking system. • 10 experiments in 15 minutes • Fraction & total flow • From 1 mL to continuous flow • Flow rate 0.1 to 30 mL/min • Reusable microfluidic chips • Possible transition of protocols from sunscreen

• Other Physics and Chemistry Equipment

Accelerating formulation optimization for vaccine and pharmaceutical development.

To create the optimal LNP, it takes a tremendous amount of time and effort to examine and pursue formulation conditions. LNPs are nanoparticles composed of multiple lipids. Therefore, it is necessary to find the optimal conditions such as the mixing ratios, the ratio of lipids to payload, and the flow rates during mixing. Furthermore, we must also consider throughput issues. Sunscreen can produce up to 96 types of small LNPs within six hours, thus solving the previous throughput problems. This means that it is possible to explore a greater number of formulation condition investigations in a single day. • Fully automated execution of up to 96 types of condition investigations within six hours • 200 μL to 2 mL per experiment • Flow rate of 0.1 to 30 mL/min • Reusable microfluidic chips • Seamless scale-up through process and protocol optimization

• Other Physics and Chemistry Equipment

The latest published paper utilized Abby. This will be an online seminar featuring Associate Professor Yosuke Katsuta from the Graduate School of Advanced Science and Technology, Kumamoto University, who is also a co-founder of StapleBio. He is working on RNA hacking technology development aimed at altering the higher-order structure of target mRNA using short nucleic acids named Staple nucleic acids, with the goal of controlling gene expression. He will present the latest data focusing on the results of cell experiments and animal experiments in the development of this technology. Related paper on the lecture content: "Staple oligomers induce a stable RNA G-quadruplex structure for protein translation inhibition in therapeutics" | Nature Biomedical Engineering

[Speaker] Yoshirō Tsuruhara, Representative of Auto Insight Inc. / Technology Journalist and Editor [Key Lecture Content] The global automotive industry is undergoing significant upheaval. The term "CAST," which is bringing about even greater changes than the previously used keyword "CASE," is at the forefront. It stands for four elements: "China," which has begun to lead global automotive technology; "AI" (Artificial Intelligence), which is transforming the development process; "SDV" (Software Defined Vehicle), which is revolutionizing the creation of vehicle value; and "Trump," which is altering the rules of the world. What does the future of the automotive industry look like with CAST? [Lecture Items] 1. Current state of the automotive industry 2. The keyword "CAST" symbolizing transformation and its meaning 3. How China is dismantling the old order of the automotive industry 4. Generative AI infiltrating all development processes 5. How SDV is transforming "value creation" in the automotive industry 6. How the second Trump administration will change the rules of the global automotive industry 7. Changes in how the automotive industry generates revenue 8. Q&A

[Lecture Items] 1. Energy-saving Project for Data Centers National Research and Development Agency New Energy and Industrial Technology Development Organization Next Generation Green Data Center Technology Development Project Project Manager Toshiyuki Ando 1. About NEDO 2. Overview of the Next Generation Green Data Center Technology Development Project 3. Future of Data Centers 4. Elements Necessary for Energy Saving 5. Overview of Research and Development 6. Q&A / Business Card Exchange 2. Technology Trends of GaN Power Devices Expected to Contribute to Energy Saving in Data Centers and Other Industrial Applications Professor Noriyuki Iwamuro, Tsukuba University, Mathematical and Physical Sciences 1. Current and Future of the Power Device Market 2. Key Points in Power Device Development 3. Technologies Supporting the Latest Silicon MOSFETs 4. Why GaN Devices for Data Centers 5. Latest Technologies of GaN Power Devices 6. Differentiation Between GaN and SiC Power Devices 7. Q&A / Business Card Exchange

This is an announcement for a seminar hosted by our group company, Jemco Japan Management Co., Ltd. ■ Theme: "Mastering 'DX that Can Be Used on the Ground'! Business Reform in Management and Indirect Departments Utilizing DX" ■ Date and Time: November 12, 2025 (Wednesday) 14:00–15:00 ■ Format: ZOOM Webinar 【Seminar Content】 1. The 2030 Problem and Productivity Challenges in Management Departments 2. An Overview of Business Reform Utilizing Digital Technology 3. Automation of Routine Tasks with RPA (Power Automate) 4. Knowledge Search and Document Utilization with Generative AI × RAG 5. Implementation Examples of "Small-Scale DX" with Power Apps 6. Development of DX Talent and Internal Deployment Models If you wish to participate in the seminar, please apply using the URL below. (You will be redirected to the group company's site) *Please apply early as the registration will close once capacity is reached. https://www.jemco.co.jp/seminar/20251112dx/?lfpeid=kqbONicaYDDx&lfmaid=1000360919-5

At our booth, we will propose products that enable "improved production efficiency" and "cost reduction" through the stabilization of plastic molding. In particular, for recycled plastics, which have been gaining importance recently, the representatives of each device will explain the test results verified with demo machines conducted in-house. We will have a demo unit of the polymer moisture meter "AquaTrack V," and customers who bring samples will be able to conduct actual measurements. Larger samples, such as preforms, can also be measured as they are. *Please inquire in advance about the types of samples. Additionally, we will present a booklet titled "Dr. Plastic Molding's Rheology Lecture Notes," summarizing the understanding of material properties and predictions of viscosity and flowability, to those we speak with at the booth. We sincerely look forward to your visit. ◎ Exhibition Contents - Polymer moisture meter "AquaTrack V" (actual machine on display; demo measurements available) - Ultra-compact polymer dehumidifying dryer "Card Series" (full-size mock-up on display) - Capillary rheometer "R6000" (panel on display)