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  3. Unchained Labs (アンチェインドラブズ)
  4. We will exhibit at BioJapan 2024.
SEMINAR_EVENT
  • Sep 18, 2024
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Sep 18, 2024

We will exhibit at BioJapan 2024.

Unchained Labs (アンチェインドラブズ) Unchained Labs (アンチェインドラブズ)
Our company will be exhibiting at BioJapan 2024, which will be held from Wednesday, October 9. At our booth, we will showcase lipid nanoparticle (LNP) related products, as well as groundbreaking analytical devices for research and development in gene therapy and biopharmaceuticals. We invite you to visit us at Pacifico Yokohama! Exhibition details: ■ Dates: October 9 (Wednesday) - October 11 (Friday), 2024 ■ Venue: Pacifico Yokohama ■ Booth #: D-97
Date and time Wednesday, Oct 09, 2024 ~ Friday, Oct 11, 2024
Capital Pacifico Yokohama Booth: D-97
Entry fee Free
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All-in-One Protein Structure Stability Evaluation System 'UNCLE'

Simultaneous measurement of 12 applications such as thermal stability, sizing, and viscosity from trace samples.

"Uncle" is a product that allows for the acquisition of more data with a small amount of protein. The required sample volume is only 9μL. By combining three different measurement modes—fluorescence, SLS, and DLS—it is easy to evaluate the optimal formulation and the stability of proteins or viral vectors. 【Features】 ■ Measure up to 48 samples in as little as about 2 hours with just 9μL. 【Applications】 ■ Tm & Tagg ■ Tm via SYPRO DSF ■ Isothermal stability ■ Sizing and polydispersity ■ Sizing via thermal gradient ■ Refolding measurements ■ Viscosity ■ kD ■ B22 ■ G22 ■ ΔG ■ Stability of viral capsids *For more details, please refer to the PDF document or feel free to contact us.

  • Other protein analysis

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Acceleration of Gene Therapy Development through Evaluation of Lentivirus Characteristics: 'Replicon'

It enables the monitoring of potency and purity throughout the entire workflow of lentivirus research and development, accelerating gene therapy development.

"Leprechaun" is a system that analyzes whether lentivirus particles are of the correct size and structure, and can measure viral titer. It allows for the determination of the titer of lentivirus present in a sample without being misled by confusing noise (such as incomplete viruses or contamination). Not only can it measure information that was previously only obtainable separately through conventional methods like ELISA, qPCR, and transduction assays, but it also enables structural analysis that those methods could not provide, all on a single platform. Capabilities: ■ Lentivirus titer ■ Lentivirus structure ■ Exosome concentration ■ Analysis of contamination (impurities such as extracellular vesicles) Features: ■ No sample purification required ■ Physical structural analysis possible ■ Distinction between virus integrity and impurities ■ Up to 16 samples can be measured at once *For more details, please refer to the PDF document or feel free to contact us.

  • Other measurement and measuring equipment

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Protein and Nucleic Acid Quality Evaluation Device 'STUNNER'

Quality assessment of proteins, nucleic acids, AAV, LNP, etc. is possible with trace amounts and high throughput.

"Stunner" is a product that allows simultaneous acquisition of UV/Vis concentration, dynamic light scattering (DLS), and static light scattering (SLS) data from a 2μL identical sample. It enables detailed investigation of AAV and adenoviruses to measure total capsid titer and Empty/Full ratios, as well as to obtain payload concentration and size data of lipid nanoparticles all at once. You can analyze concentration, hydrodynamic size, polydispersity, and the presence of aggregates collectively, allowing you to assess the quality of proteins. This way, you can immediately determine whether your AAV, adenoviruses, lipid nanoparticles, or proteins are suitable for your purposes. [Features] ■ Measure up to 96 samples in a batch in 60 minutes*/12 minutes** *When measured by DLS **When measured by UV/Vis only [Applications] ■ AAV/Adenovirus capsid titer ■ AAV/Adenovirus Empty/Full ratio ■ Lipid nanoparticle (LNP) payload amount ■ Aggregate measurement ■ Concentration measurement ■ Sizing & polydispersity ■ B22 & kD *For more details, please refer to the PDF document or feel free to contact us.

  • Other protein analysis

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High-precision quantification tool for proteins and nucleic acids 'LUNATIC'

No complicated workflows needed! Only 2μL of sample volume required. Measure up to 96 samples in just 5 minutes.

"Lunatic" is a product that allows for easy simultaneous quantification of proteins, DNA, and RNA. The required sample volume is only 2μL, and up to 96 samples can be measured in 5 minutes. High-concentration samples can also be measured directly without dilution. 【Features】 ■ Measure 2μL, up to 96 samples in 5 minutes ■ Dynamic range coverage from 0.02 to 200 mg/mL* *for mAb ■ Outstanding accuracy and precision ■ Automation is also possible *For more details, please refer to the PDF document or feel free to contact us.

  • Analytical Equipment
  • Other protein analysis
  • Other measurement and measuring equipment

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Bench-top fully automatic buffer exchange concentration device "UNAGI"

Up to 8 samples can be processed simultaneously! Automatic and hassle-free buffer exchange and concentration that used to be complicated!

Buffer exchange and concentration must be performed as a sample preprocessing step. This is a labor-intensive task that takes a long time, requiring your presence throughout the process. "UNAGI" is a fully hands-free benchtop buffer exchange solution designed to take over this tedious task. It can process up to 8 samples simultaneously. The software is very easy to operate, allowing you to be anywhere during the work, eliminating the need to stay in the laboratory the entire time. 【Features】 ■ Simultaneous processing of up to 8 samples ■ Efficient solvent removal prevents sample adsorption, achieving over 96% recovery rate ■ Built-in recipes for UF/DF buffer exchange ■ User-friendly software ■ Concentrates up to 8 diluted samples from 48mL to 8mL in one go *For more details, please refer to the PDF document or feel free to contact us.

  • Other Protein Research Software
  • DNA analysis

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Ultra-fast viscometer "Honeybun"

You can measure 10 samples at once! There's no need to clean expensive chips that are prone to clogging!

"Honeybun" is a high-speed viscometer that can output data almost simultaneously with processing. Regardless of whether the number of samples is 1 or 10, it uses a few microliters of each sample through a microchannel and reads viscosities in the range of 0.5-150 cP within a few minutes. No pre-treatment or cleanup of samples is necessary. 【Features】 ■ Can measure up to 10 samples at once ■ Required sample volume: 35μL (can measure from 15μL; see application notes) ■ Measurement completed in under 1 minute (for viscosities below 10 cP) ■ Measurement range: 0.5-150 cP ■ No cleaning required and maintenance-free *For more details, please refer to the PDF document or feel free to contact us.

  • Other bio-related products

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The "Sun Series" that covers the development of lipid nanoparticles from upstream to downstream.

Seamlessly transition from formulation condition screening to scale-up and GMP manufacturing. Accelerate LNP product development.

The development of lipid nanoparticles (LNPs) faces many challenges. The formulation, optimization, and scale-up for clinical trials are complex, costly, and a race against time. Our LNP solutions are designed to accelerate all steps of LNP synthesis and characterization. Sunscreen accelerates LNP formulation screening by reducing costs and time, generating up to 96 unique LNP formulations within 6 hours. Next, using Sunshine, you can develop, optimize, and scale up protocols with the appropriate formulations obtained from Sunscreen. When it comes to the clinical trial phase, Sunbather can accommodate LNP production in a GMP environment using the same processes and microfluidic chips (Sunny) utilized by Sunscreen and Sunshine. In this way, the Sun series allows for a seamless transition from screening formulation conditions to scale-up and GMP manufacturing, as they all use the same pumps and microchannel chips. *For product details, please download various materials.

  • Other Physics and Chemistry Equipment

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GMP-compliant lipid nanoparticle automatic synthesis system Sunbather

Accelerating formulation optimization for vaccine and pharmaceutical development.

The transition from LNP to GMP is a costly and complicated process. Typically, this requires switching equipment, using different flow paths and mixing devices, and essentially re-developing and re-validating everything that has been painstakingly done so far. With Sunbather, the transition to GMP can be done easily thanks to its recording features, interchangeable flow paths, and easily transferable design. Sunbather uses the same mixing process and protocols as the Sunscreen and Sunshine from the same Sun series, allowing for easy transition of adjusted formulation conditions to GMP. - Up to 1.8 L/h - Integrated inline dilution - Fully interchangeable flow paths - A wide variety of mixing devices - Software compliant with 21 CFR Part 11 - Process transferable from Sunshine

  • Other Physics and Chemistry Equipment

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Lipid nanoparticle automatic synthesis system Sunshine

Efficient mass production of LNPs - Supporting everything from small-scale condition testing to scale-up.

Once we succeed in finding the optimal formulation conditions for sunscreen, let's use Sunshine to adjust the size of the LNP. Furthermore, we will optimize the protocols and processes for scaling up. We will find the ideal flow rate and explore different mixing options. Next, we will adjust these to the appropriate dilution factor that can keep them stable. Once everything is in place, Sunshine will transition to continuous mode, allowing us to produce several dozen liters in a day. In other words, we will achieve process development and scaling up on a single platform. Many researchers have likely been looking forward to the birth of such a groundbreaking system. • 10 experiments in 15 minutes • Fraction & total flow • From 1 mL to continuous flow • Flow rate 0.1 to 30 mL/min • Reusable microfluidic chips • Possible transition of protocols from sunscreen

  • Other Physics and Chemistry Equipment

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Automatic Synthesis and Screening System for Lipid Nanoparticles Sunscreen

Accelerating formulation optimization for vaccine and pharmaceutical development.

To create the optimal LNP, it takes a tremendous amount of time and effort to examine and pursue formulation conditions. LNPs are nanoparticles composed of multiple lipids. Therefore, it is necessary to find the optimal conditions such as the mixing ratios, the ratio of lipids to payload, and the flow rates during mixing. Furthermore, we must also consider throughput issues. Sunscreen can produce up to 96 types of small LNPs within six hours, thus solving the previous throughput problems. This means that it is possible to explore a greater number of formulation condition investigations in a single day. • Fully automated execution of up to 96 types of condition investigations within six hours • 200 μL to 2 mL per experiment • Flow rate of 0.1 to 30 mL/min • Reusable microfluidic chips • Seamless scale-up through process and protocol optimization

  • Other Physics and Chemistry Equipment

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Bench-top fully automatic buffer exchange concentration device "UNAGI"

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Benefits of LNP Automated Process Optimization Using Sunshine - Columbia University Case Study

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Mastering Mixing: Sunny's Selection Guide

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GMP-compliant automatic synthesis system for lipid nanoparticles Sunbather

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[Application Note] Accelerating LNP Product Development with Sun Series at Lightning Speed

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Flexibility in Nanoparticle Development by Sunshine: Process Optimization and Scale-Up of Synthetic Nanomedicine

Flexibility in Nanoparticle Development by Sunshine: Process Optimization and Scale-Up of Synthetic Nanomedicine

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Process optimization of lipid nanoparticles using Sunshine and production of lipid nanoparticles for preclinical use.

Process optimization of lipid nanoparticles using Sunshine and production of lipid nanoparticles for preclinical use.

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Accelerating LNP formulation screening using automatic microfluidic technology for sunscreen.

Accelerating LNP formulation screening using automatic microfluidic technology for sunscreen.

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Lipid nanoparticle automatic synthesis system Sunshine

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Automatic Synthesis and Screening System for Lipid Nanoparticles Sunscreen

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[Seminar] Expansion from Chubu Electric Power's Telemetry to Multi-Infrastructure DX Business

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[Speaker] Tadahiro Maruyama, Director of the Business Creation Division, Chubu Electric Power Co., Inc. (Also Deputy COO of Chuden Telemetering LLC) [Key Lecture Content] Chubu Electric Power is expanding telemetering through a smart meter communication network to gas and water services. In the next phase, we aim to integrate these accumulated data into a multi-infrastructure DX business, merging with energy and water services, and striving for a circular and sustainable community across our entire group. This time, I will explain the actual initiatives related to these efforts. [Lecture Items] 1. Automatic Meter Reading by Chubu Electric Power 2. Current Status of Chubu Electric Power's Telemetry Business 3. Business Transformation through Infrastructure DX in the Electric Power Sector 4. Horizontal Expansion of Infrastructure DX to Water Services 5. Smart City Services through Data Utilization 6. Q&A / Business Card Exchange

Dec 08, 2025

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[Seminar] The Most Effective Teaching Methods for Personal Growth

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[Speaker] Daihei Yamamoto, CEO of F6 Design, Inc. Strategic Consultant / Data Scientist [Lecture Topics] 1. Why is it difficult for "self-driven talent" to emerge from Japanese workplaces? 2. Shifting to a "non-teaching teaching method" - How to change interactions with subordinates 3. Strengthening communication skills through WHI (Why-How-If) 4. Creating an environment that allows for "safe failures" and systems that support self-drive 5. Q&A

Dec 08, 2025

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PV Seminar (Free) Now Ongoing

Solar Power Measurement "See, Touch, Experience, and Learn" PV Seminar (Free. 1/21 13:00~)

  • NEW
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To learn more about solar cells, to understand measurement methods, to acquire know-how related to measurements, and to actually try using measuring instruments, we have established a "PV Technical Center" on our headquarters premises, which also serves as a showroom. This center provides support services in the field of measurements for solar power generation, addressing various questions and requests from customers. At the PV Technical Center, we hold PV seminars (free of charge). Please apply through the detailed application URL provided.

Dec 08, 2025

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December 17 (Wednesday) Event [Free! Zoom Webinar] Public Course "OJT Leader Development Course" Demonstration Seminar

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In recent years, many people have been facing the challenge of "how to ensure retention and quickly turn new employees into productive members" due to the difficulty in hiring new graduates and the diversification of the environment and values in which young employees have grown. In this seminar, we will introduce some key points of "OJT Leader Development" from the training of the public course "OJT Leader Development Course" scheduled for March next year, based on the know-how cultivated in actual OJT leader training. We will share points that can be immediately practiced in the field, and we look forward to your enthusiastic participation! *Please apply through our company website below. *We have prepared two dates. Please choose a date that is convenient for you. Date: December 17, 2025 (Wednesday) 12:00 PM - 1:00 PM Format: Zoom Webinar Cost: Free Application Deadline: December 15 (Monday) Capacity: 50 people *Registration will close once the capacity is reached. [Content] - Positive role recognition - Understanding the environment and values that have developed - Imagining the "ideal self" as an OJT leader - Skill set for development and more.

Dec 08, 2025

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December 18 (Thursday) Event [Free! Zoom Webinar] Public Course "OJT Leader Development Course" Demonstration Seminar

  • NEW
  • SEMINAR_EVENT

In recent years, many people have been facing the challenge of "how to ensure retention and quickly turn new employees into productive members" due to the difficulty in hiring new graduates and the diversification of the environment and values in which young employees have grown. In this seminar, we will introduce some key points of "OJT Leader Development," which is part of the public course "OJT Leader Development Course" scheduled for March next year, based on the know-how cultivated in actual OJT leader training. We will share points that can be immediately applied in the field, and we look forward to your enthusiastic participation! *Please apply through our company website below. *We have prepared two days for the schedule. Please choose a date that works best for you. Date: December 18, 2025 (Thursday) 14:00–15:00 Format: Zoom Webinar Cost: Free Application Deadline: December 15 (Monday) Capacity: 50 people *Registration will close as soon as we reach capacity. [Content] - Positive role recognition - Understanding the environment and values that have developed - Visualizing the "ideal self" as an OJT leader - Skill set for development and more.

Dec 08, 2025

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