東京インスツルメンツ List of Products and Services

It is a cutting-edge system for digital chromosome analysis that features computer-assisted counting, indexing, karyotype analysis, and automated unmanned scanning. HiBand significantly enhances laboratory productivity and increases the reliability of diagnostics for cytogenetics labs.

• Other Nucleic Acid/DNA Research
• Analytical Equipment

The digital pathology tissue analysis system PathFusion is a system that automates and assists the measurement and analysis of pathology samples that were previously done manually. By automatically scanning samples, it digitizes specimen samples (whole slide imaging) and assists with measurement, analysis, FISH, and diagnosis in an automated or semi-automated manner. Whole slide imaging (WSI) captures the original staining state of the samples, allowing for the observation of slide images in a database indefinitely. Based on digital data, it enables the matching between H&E and IHC stained slides and FISH slides, as well as clustering of IHC stained cells, thereby reducing the workload and operation time involved in tissue observation and analysis.

• Imaging and image analysis equipment
• Other appearance and image inspection equipment
• Image analysis

This is a device that enables the reuse of liquid helium, which has become difficult to obtain due to rising prices. It collects helium gas that evaporates from low-temperature experimental devices using liquid helium and achieves helium reuse by automatically recondensing it. The system consists of a dewar equipped with a mechanical refrigerator, an automatic controlled gas handling system (GHS), and a gas bag as its basic components. The configuration and liquefaction capacity can be discussed according to your preferences. It can be applied to various uses such as dilution refrigerators, scanning tunneling microscopes (STM), NMR, and ARPES (angle-resolved photoemission spectroscopy).

• others

This product is a light source device that controls up to 32 types of LED channels to reproduce and illuminate a simulated sunlight spectrum distribution. It allows for the control of LED intensities at multiple wavelengths, much like an audio device's "equalizer," enabling the reproduction of various wavelength spectrum distributions. With long-lasting LED elements (10,000 to 100,000 hours), it guarantees a more stable light irradiation for a longer duration compared to conventional light source devices using xenon lamps and air mass filters. It has been adopted in over 40 countries and is used in many university laboratories and manufacturing sites of companies.

• others

In general bioimaging, 3D images are obtained by continuously measuring 2D images in the depth direction. However, this product, the "Holographic Microscope for Cell Observation 3D Cell Explorer," utilizes holography and tomography technologies to measure the differences in refraction within cells in three dimensions with a single measurement, producing high-resolution digital images on the nanometer scale that exceed the diffraction limit of light almost instantaneously. High-resolution images can be captured in just a few seconds, and by digitally staining them, it allows for comprehensive observation of the cell interior from various perspectives. The laser light used is a weak laser that does not impact the cells, enabling non-invasive measurements to observe the cells in their natural state. Once powered on, it starts up immediately, and measurements can begin right away. Sample preparation, staining labels using expensive reagents, and the configuration of the optical system are all performed automatically, eliminating the need for complex adjustments. Additionally, user-friendly software is provided, allowing for intuitive operation despite its high functionality, making it easy to use.

• Other physicochemical equipment
• Chemicals
• Testing Equipment and Devices

Conventional organic chemistry experiments (reaction experiments and synthesis experiments) require constant stirring of solutions and temperature adjustments, which means that the experimenter must essentially be present throughout the duration of the experiment. Furthermore, these experiments often take a long time, with some lasting an entire day. They are considered more difficult than physical or inorganic experiments, and the physical and mental state of the experimenter can significantly affect the results, which has been a challenge. The device "FlexyCUBE" is a system that automates these organic chemistry experiments (reaction experiments and synthesis experiments). It can accommodate up to six reaction vessels, allowing for the simultaneous execution of six different experiments. The software interface is user-friendly, making it easy to set experimental conditions and generate reports. The number of reaction vessels can also be increased as needed. It is possible to monitor six different experiments simultaneously.

• Other physicochemical equipment
• Chemicals
• Testing Equipment and Devices

The "Nanofinder FLEX" is a versatile device equipped with the basic performance of the 3D micro laser Raman spectrometer "Nanofinder30," featuring modularized units. It maintains high spatial resolution and sensitivity while pursuing thorough miniaturization and achieving low cost. The software is the well-established dedicated Nanofinder software, which is rich in content and excels in image representation (visualization). 【Features】 ■ High performance, compact size, low cost ■ Raman spectroscopic imaging with spatial resolution below 300nm ■ High sensitivity (detecting the fourth harmonic of Si within one minute) with low illumination laser of 4mW ■ Adoption of confocal laser microscopy ■ Raman optical unit reduced to A4 size *For more details, please refer to the PDF document or feel free to contact us.

• Spectroscopic Analysis Equipment
• Analytical Equipment and Devices
• Laser microscope

The multi-focal Raman microscope Phalanx-R is the world's first Raman microscope that can capture 2D Raman images "in an instant," just like taking a photograph. It enables real-time imaging of dynamic chemical reactions, which was previously impossible, and allows for high-speed observation of molecular distribution and changes within cells while minimizing light damage to the samples.

• Spectroscopic Analysis Equipment
• Laser microscope
• Analytical Equipment and Devices

The particle inspection device PARTi (manufactured by PERSYS) is a newly proposed particle inspection device that can quickly inspect the cleanliness of items used in clean rooms (brought into clean rooms). It allows for the installation of precision machined parts, sample containers, cleanroom garments, gloves, and more in a dedicated chamber, where clean air that has passed through a HEPA filter is blown to remove adhering particles, and the particle count is measured using a particle counter mounted at the bottom of the device. No pre-treatment of the inspection items is necessary, and a dedicated sample fixture is included, allowing for inspections under various particle inspection conditions. Since there is no need to immerse the inspection items in liquid or rotate them in a drum, any item can be easily inspected. It is convenient for users to establish their own measurement conditions and is suitable for routine inspections. The device is available in two types according to the application: one for measuring particles from 0.1 to 5.0 μm and another for 0.3 to 5.0 μm. This particle inspection device is from a clean technology specialist company founded in 1988, which handles parts cleaning, technology development, production, and maintenance of equipment used in high-level clean rooms for the semiconductor industry, primarily centered in Silicon Valley, USA.

• Defect Inspection Equipment
• Visual Inspection Equipment
• Other inspection equipment and devices

The "VariWave" (manufactured by LAMBDA Technologies in the United States) is a frequency-variable microwave oven equipped with patented VFM technology (Variable Frequency Microwave) that enables "high-speed curing and precise adhesion of adhesives and resins." While conventional microwave ovens and industrial microwave heating devices use a fixed frequency of 2.45 GHz, VFM sweeps rapidly across the 5 to 7 GHz range. This VFM oven has numerous features that overturn the conventional wisdom of microwave heating, including uniform heating throughout the chamber, the ability to introduce metal objects, and temperature control of the heated items (including ramp rate control and constant temperature maintenance). These features make it possible to perform treatments in the curing process of adhesives and resins that were previously impossible, thereby establishing an innovative curing process. The device comes standard with ports for various sensors, a non-contact thermometer, closed-loop high-precision temperature control, a sample observation camera, and NW10x2 ports for gas introduction and exhaust. Additionally, it is possible to conduct treatments in a simple vacuum environment or under a gas atmosphere as needed.

• Other processing machines
• Resin processing machine
• others

EyeTech, developed by ambivalue (Netherlands), which has sold over 2,000 particle analysis devices worldwide, measures individual particle sizes and shapes quickly and accurately. This device is equipped with two measurement methods: scanning laser and camera, allowing for the evaluation of particle diameter, concentration, and shape for each individual particle. The diameter is measured based on the time the particle obstructs the scanning laser, while the particle shape is obtained from real-time analysis of images captured by the camera. Since both measurement methods accurately assess individual particles, they provide correct statistical information about the particles. A wide variety of measurement cells are available, enabling the analysis of diverse samples such as suspensions, dry powders, emulsions, and aerosols. For example, samples containing numerous unknown particles, like muddy water, can also be evaluated. The high-performance software allows anyone to easily conduct measurements, and the automatic report generation feature produces organized reports with measurement data and particle images immediately. No adjustments or calibrations of the device are necessary. It can be used in a wide range of fields, including quality control, product development, and environmental analysis.

• Water quality testing
• Soil testing
• Other powder equipment

This is an electronics module for measuring and analyzing high-speed phenomena of light using TCSPC: Time Correlated Single Photon Counting.

• Laser microscope
• Optical Measuring Instruments
• Other measurement, recording and measuring instruments

C-RED2 is an innovative near-infrared camera developed by the French company First Light Imaging, which specializes in high-speed EMCCD and MCT cameras, achieving higher speed and lower noise compared to conventional products.

• High Speed Camera

Nanofinder - High-quality Raman spectral analysis and evaluation with a spatial resolution of 200 nanometers. Tokyo Instruments pioneered the industry's first "Raman imaging with a spatial resolution of 200 nanometers" 20 years ago and continues to challenge itself with "cutting-edge analysis and evaluation technologies."

• Spectroscopic Analysis Equipment
• Analytical Equipment and Devices
• Laser microscope

The PHTORN RT (manufactured by ESSENT Optics) is a spectrophotometer that automatically measures reflectance, transmittance, and polarization of optical elements such as filters, mirrors, and PBS cubes, making it ideal for evaluating and quality controlling flat optical components. It features a unique fully automated optical setup that eliminates the need to change measurement accessories for each reflectance and transmittance measurement, allowing for continuous measurement of both. This significantly improves work efficiency and greatly reduces tact time. It is a device that manufacturers responsible for routine evaluation of optical coatings and quality control of finished products should definitely use. It supports a wide wavelength range from 185 nm to a maximum of 5200 nm (with fully automatic detector switching), includes beam shift correction during oblique incidence measurements (with fully automatic detector position correction), is equipped with P and S polarization elements (with fully automatic switching), has a mercury lamp for wavelength calibration, and features a measurement data report generation function, all designed to streamline optical element evaluation and quality control tasks. In terms of performance, it has a double beam system with a high baseline stability of 0.1%/hour, enabling high stability and high precision measurements. The device is compact, measuring 420×610×270 mm, and can be placed on a tabletop.

• Spectroscopic Analysis Equipment
• Analytical Equipment and Devices
• Other measurement, recording and measuring instruments

It specializes in processing that maximally utilizes the characteristics of femtosecond lasers, enabling precise microfabrication on delicate biological samples, transparent materials, thin films, and all kinds of materials. In recent years, it has also been anticipated as a new biological molecular scalpel, applying photon craft technology to delicate biological samples without causing damage to surrounding tissues or cells.

• Other processing machines

This is a reference sample for AFM and SPM calibration. You can choose the most suitable one according to your application. - Calibration of X-axis, Y-axis, and Z-axis - Nonlinearity detection - Detection of nonlinearity in the horizontal and vertical directions - Detection of angular deformation - Determination of tip shape parameters (aspect ratio, radius of curvature), tip degradation, and contamination control. - Detection of hysteresis, creep, and cross-coupling effects - Tip characteristics - 3-D visualization of the scanning tip - Determination of the aspect ratio of the tip - Calibration in sub-micron units on the X-axis or Y-axis It can also be used for practice in SPM measurements and for student experiments.

• Other microscopes
• Other laboratory equipment and containers

EKSPLA has been manufacturing and selling lasers and related electrical equipment for many years, consistently delivering cutting-edge products to the market. In particular, high-power electronics (high-speed/high-voltage power supplies) is one of the core technologies that EKSPLA excels in. To accommodate a wide range of applications from R&D to OEM, we also offer customization based on customer requests, so please feel free to contact us.

• Other physicochemical equipment

This is a fluorescently labeled FISH probe that stains the entire chromosome of the specified chromosome number. It allows for high-sensitivity visualization of individual chromosomes in cells during metaphase, enabling the identification of both chromosome number and structural chromosomal abnormalities. There are kits available that allow you to choose from four fluorescent colors and stain up to three different chromosome numbers simultaneously. Chromosomes are available for three species: human, mouse, and rat. 【Features】 ■ Ready-to-use product ■ Choice of fluorescent dyes from four colors ■ Simultaneous staining of up to three types of chromosomes ■ For confirming the number of chromosomes and checking for translocations between chromosomes

• Other Nucleic Acid/DNA Research
• DNA labeling kit
• Staining Reagents

The dichroic mirror is designed for an incident angle of 45°. It allows transmission on the longer wavelength side of a specific wavelength while reflecting the shorter wavelength side, enabling spectral separation.

• Other optical parts

This bandpass filter is a hard-coated filter with high transmission rate and high blocking performance. It allows transmission only in the wavelength bands around a specific wavelength, blocking other wavelength ranges.

• Other optical parts

This notch filter is a hard-coated filter with high blocking performance and a narrow bandwidth. It blocks only the narrow wavelength range before and after a specific wavelength, while allowing other wavelength ranges to pass through, enabling spectral separation. In Raman spectroscopy, it is possible to simultaneously detect Stokes Raman scattered light (longer wavelength than the laser) and anti-Stokes Raman scattered light (shorter wavelength than the laser).

• Other optical parts

The standard long pass filter is a high-performance hard-coated filter with high blocking performance and high transmittance. It has a steep edge transition (approximately 1.25% of the laser wavelength) at a specific wavelength, allowing it to transmit longer wavelengths and reflect shorter wavelengths, enabling spectral separation. In particular, in Raman spectroscopy, it is necessary to separate Rayleigh scattered light (laser wavelength) from weak Raman scattered light, and the steep edge transition and high blocking performance make it easy to measure Raman spectra.

• Other optical parts

The short-pass dichroic mirror is designed for an incident angle of 45°. It reflects wavelengths longer than a specific wavelength while transmitting shorter wavelengths, allowing for spectral separation.

• Other optical parts

EnviroESCA measures samples in a near-atmospheric pressure environment (up to 0.1 atm), eliminating the need for the ultra-high vacuum environments traditionally required. It can start measurements just a few minutes after introducing liquid, aqueous, volatile, or highly degassing porous samples into the EnviroESCA sample chamber. Not only can it analyze samples that conventional XPS would have given up on, but it also serves as a powerful tool for pioneering new research fields by freely controlling ambient gases and temperatures. It easily enables measurements under device operating conditions, known as "operando measurements," which are rapidly gaining attention. With EnviroESCA, which does not require ultra-high vacuum conditions, quality inspections on production lines that require a large number of inspections in a short time can be efficiently conducted. It is also possible to use robots and auto-loaders to batch process samples from introduction to measurement without human intervention. EnviroESCA, which dispels the conventional notion of X-ray photoelectron spectroscopy being limited to ultra-high vacuum environments, drives novel research and development and provides entirely new applications for X-ray photoelectron spectroscopy in fields such as medicine, biology, and life sciences.

• Spectroscopic Analysis Equipment

The ultra steep long pass filter is a high-performance hard-coated filter with high transmission rates and a wide blocking range. It features a steep edge transition (less than 0.5% of the laser wavelength) at a specific wavelength, allowing it to transmit longer wavelengths while reflecting shorter wavelengths, enabling spectral separation. In particular, in Raman spectroscopy, it is necessary to separate Rayleigh scattered light (laser wavelength) from weak Raman scattered light, and the steep edge transition and high blocking performance make it easy to measure Raman spectra.

• Other optical parts

The ultra steep short pass filter is a high-performance hard-coated filter with a steep cutoff, high blocking performance, and transmittance. It has a sharp edge transition at a specific wavelength, allowing shorter wavelengths to pass through while reflecting longer wavelengths, enabling spectral separation.

• Other optical parts

This product features a compact low-temperature refrigeration unit with high cooling performance. The vibration of the cold head is very low, making it ideal for cooling systems that are sensitive to vibrations. Additionally, the cold head is designed to be directly connected to a vacuum chamber, facilitating easy integration into vacuum systems. By employing a closed-loop system for cooling, it can be used maintenance-free. Our company also offers the possibility of custom system fabrication using this product.

• Refrigerators and freezers

The dichroic mirror is designed for an incident angle of 45°. It allows transmission on the longer wavelength side of a specific wavelength while reflecting the shorter wavelength side, enabling spectral separation.

• Other optical parts

This is a bandpass filter designed to optimize the detection of bright lines in gas spectra, suitable for the mid-infrared region. We offer filters with a central wavelength range of 2.7 to 9.46 μm. A variety of filters are available for wavelengths commonly used in gas detection. They can be used for detecting gases such as H2O, CH4, CO2, CO, N2O, and O3.

• Other optical parts

This bandpass filter is a hard-coated filter with high transmittance and OD value. It allows transmission only in the wavelength bands around a specific wavelength, while blocking other wavelength ranges.

• Other optical parts

This is a filter set for fluorescence measurement, composed of three high-performance filters (Exciter, Dichroic, Emitter) that boast high durability against light damage and environmental degradation. It can be mounted on filter cubes from most microscope manufacturers. (Compatibility confirmed with Olympus U-MF2 and Nikon TE-2000 filter cubes.) *Microscope filter cube is not included.

• Other optical parts

This notch filter is a hard-coated filter with high blocking performance and a narrow bandwidth. It blocks only the narrow wavelength range before and after a specific wavelength, while allowing other wavelength ranges to pass through, enabling spectral separation. In Raman spectroscopy, both Stokes Raman scattering light (longer wavelength than the laser) and anti-Stokes Raman scattering light (shorter wavelength than the laser) can be detected simultaneously.

• Other optical parts

This laser line filter is a high-performance hard-coated filter with high transmittance and a wide blocking range. It allows only a narrow band very close to a specific laser wavelength to pass through while blocking other wavelength ranges. In gas lasers, in addition to the main oscillation wavelength, there are plasma lines that can interfere with spectral measurements. In this case, only the laser oscillation line can be used, which enhances the purity of the laser.

• Other optical parts

The Nanoedge long pass filter is a high-performance hard coat filter that features a steep edge transition (less than 0.2% of the laser wavelength) at a specific wavelength, allowing it to transmit longer wavelengths while reflecting shorter wavelengths, thus enabling spectral separation. In particular, in Raman spectroscopy, it is necessary to separate Rayleigh scattered light (laser wavelength) from weak Raman scattered light, and the steep edge transition and high blocking performance make it easy to measure Raman spectra.

• Other optical parts

SFG (Sum Frequency Generation) spectroscopy is a vibrational spectroscopy method that utilizes second-order nonlinear optical effects. This spectroscopy method has high interfacial selectivity, allowing for the analysis of the molecular vibrational structure and orientation of monolayers at surfaces or interfaces. By sweeping the wavelength of infrared light across the surface (or interface) and measuring, molecules can be identified from the spectrum, and by changing the polarization of the incident and emitted light, the molecular arrangement can be measured. The wavelength range of infrared light is 4300 to 625 cm^-1 (2.3 μm to 16 μm), with a resolution of less than 6 cm^-1. There are also Phase-Sensitive SFG modules and SFG microscope modules that can measure phase and intensity. Our company is the exclusive distributor in Japan for EKSPLA's SFG spectroscopy systems.

• Spectroscopic Analysis Equipment
• Analytical Equipment and Devices
• Food Testing/Analysis/Measuring Equipment

This product is a compact design semiconductor laser that can also be used for embedded applications. We offer a wide range of 27 wavelengths from 375nm to 1064nm. It features high stability through active temperature control using electronic cooling elements, excellent beam quality (TEM00), and modulation capabilities with external signals up to 1.5MHz.

• Other physicochemical equipment

TRACEiT (non-contact 3D surface shape and roughness measurement device) is a non-contact 3D surface shape/roughness (Ra/Rq/Rz) measurement device that uses white LEDs. It can measure an area of 5 mm × 5 mm in a short time (approximately 10 seconds) with a resolution of a few micrometers. Additionally, this device is equipped with a built-in CCD camera, allowing for comparisons with CCD images. Furthermore, by using optional transmitted lighting, it can measure transparent materials, the brightness and darkness of paper, and can be combined with manual or automatic stages for extensive measurements.

• 3D measuring device

Sphere Optics manufactures transmission sheets and reflection sheets using Zenis polymer. Both have characteristics close to an ideal Lambertian over a wide wavelength range from 250 nm to 2500 nm, making them suitable for light scattering measurements and calibration. When special curves or shapes are required instead of flat reflective panels in quality control or production processes, Zenis polymer sheets, which are sheet-like, are useful. Additionally, a special adhesive for attaching Zenis polymer sheets can be optionally applied. Please consult us regarding special sizes and reflectivity. We also offer lightweight large diffusion reflection targets using reflection sheets.

• Other consumables
• Other optical parts

Confocal micro-Raman spectroscopy allows for atmospheric, non-destructive, non-contact, and trace analysis. Furthermore, it enables the analysis of aqueous solutions, glass samples, and submicron-sized foreign substances, which are difficult to measure with infrared absorption spectroscopy. The Nanofinder FLEX is a highly sensitive and high spatial resolution confocal micro-laser Raman spectrometer that can produce Raman images of small areas in a short time. Additionally, each module (excitation laser, Raman optical unit, spectrometer) is connected via fiber, allowing for flexible installation locations.

• Spectroscopic Analysis Equipment
• Analytical Equipment and Devices
• Laser microscope

Our original fluorescence lifetime measurement device and fluorescence spectrum measurement device adopt TCSPC: Time Correlated Single Photon Counting, allowing for fluorescence lifetime measurements from nanoseconds to microseconds. By combining high-sensitivity CCD detectors for spectroscopy and high-performance spectrometers, we can accommodate PL spectrum measurements and PLE measurements. Additionally, we can also support integration with Raman measurements and other techniques, broadening the scope of evaluation. We can also accommodate the reuse of existing devices and gradual system expansions. From individual components to full systems, we offer a wide range of optimal solutions.

• Other microscopes
• Spectroscopic Analysis Equipment
• Analytical Equipment and Devices

The pco.edge is a groundbreaking imaging camera equipped with sCMOS (scientific CMOS), known as the next-generation CMOS image sensor. It condenses high resolution, low readout noise, high frame rate, and a wide dynamic range into a single camera, features that are not found in conventional CMOS and CCD cameras. The pco.edge5.5 is characterized by high resolution and the ability to switch between global shutter and rolling shutter modes. It also offers the option of a color camera. The pco.edge4.2 features high quantum efficiency, low readout noise, and a wide dynamic range. Additionally, it offers several types of high-precision synchronization modes, making it suitable for various applications when mounted on microscopes. Bringing to light - this camera expands the possibilities for measurements, observations, and analyses that were previously difficult to achieve.

• Optical microscope

The ultra-compact spectrometer (manufactured by Broadcom) is an ultra-compact spectrometer designed for industrial, portable, and embedded applications, such as the popular handheld measuring devices and drone-mounted systems. In particular, the Qmini is the size of a matchbox at 64.0×42.0×14.5mm and weighs only 60g, making it an ultra-lightweight spectrometer ideal for device development that prioritizes size. For device development that emphasizes resolution, please choose the Qwave. It is equipped with a built-in 2500 to 3648 pixel CCD detector, providing high wavelength resolution measurement data at 16 bits. For OEM mass production, we can accommodate custom specifications and OEM pricing, so please consult with us. In addition to standard transmission, absorption, and reflection measurements, it supports various spectral measurements such as wavelength monitoring of variable wavelength light sources, fluorescence measurements, and colorimetry. The dedicated control software, WAVE, features a clear and concise user interface and is standard software with many distinctive functions, including spectral measurement and display. We also provide an SDK for custom program development. Models that are available for immediate delivery are also available.

• Spectroscopic Analysis Equipment
• Sensors
• Optical Measuring Instruments

This is a halogen lamp and deuterium lamp from StellarNet. It is ideal as a light source for the company's fiber multi-channel spectrometer with an SMA905 fiber optic connection. It can be widely used for various reflection and transmission measurements. There are also options available with filter mounting specifications and cuvette holder specifications. Additionally, there is a deuterium-halogen combination light source that can be used over a wide wavelength range from UV to VIS to NIR.

• Spectroscopic Analysis Equipment

The 3D Cell Explorer-fluo, a holographic and fluorescence microscope for cell observation, is an innovative device that combines 3D refractive index imaging and 2D fluorescence imaging using holography and tomography technologies. It allows for rapid and easy observation of the internal structures and organelle distributions of cells and tissues. By overlaying fluorescence images of various cellular organelles and cell membranes that have been fluorescently labeled with refractive index images, it is possible to calibrate the digital staining to match the staining images of the fluorescent labels. By applying this calibrated digital staining to the 3D refractive index image, the 2D fluorescence images can be extended into 3D images, visualizing the three-dimensional distribution. This calibration process allows for a correlation between fluorescence staining and digital staining, enabling compatibility with unstained samples. The constructed 3D images can be enlarged, reduced, rotated, and displayed in cross-sections, allowing for comprehensive observation of the interior of cells from various perspectives.

• Other cell research
• Other microscopes and optical inspection equipment
• Refractometer