サーモフィッシャーサイエンティフィック株式会社／Thermo Fisher Scientific K.K. List of Products and Services

The Thermo Scientific Vanquish Fraction Collector (VFC) is a system that enables peak-triggered fractionation using UV, CAD, and MS detectors. With CAD and MS detection, it has become possible to fractionate and evaluate unknown components and impurities that were difficult to detect with conventional UV detection. This application note explains the features of the VFC equipped with innovative valve technology, using examples from plant extracts. It provides detailed practical know-how from parameter settings for accurate fractionation to applications on a semi-preparative scale. 【Features】 ■ Low contamination: Cleaning functions for needle and buffer loop ■ High precision fractionation: Automatic calculation of delay volume, peak-triggered fractionation ■ Excellent versatility: Diverse fractionation settings using UV, CAD, and MS detection ■ High reliability: Fractionation enabled by innovative valve technology

• Analytical Equipment and Devices

The HPLC Charged Aerosol Detector (CAD) system is a solution that allows for the rapid and highly accurate quantification of lipids in liposome formulations. This technical sample presents the results of validation using the ASTM method across 12 system configurations at 4 sites (Thermo Scientific Vanquish Flex UHPLC and Vanquish Core HPLC). Reliable results were obtained across all systems, and they passed the system suitability tests. Additionally, excellent separation performance was confirmed using the Thermo Scientific Hypersil GOLD column. 【Features】 ■ High precision quantification: Quantification is possible in the range of 0.2 to 300 µg/g using linear, quadratic, and log-log calibration curves. ■ High reliability: Passed system suitability tests at all sites. ■ Excellent performance: High separation capability and rapid analysis with the Hypersil GOLD column. ■ Efficient analysis: Consistent responsiveness and high-precision results obtained quickly.

• Analytical Equipment and Devices

This application note introduces the analysis of polymer compounds using size exclusion chromatography (SEC) with the Vanquish Charged-Aerosol Detector (CAD). The CAD has approximately 100 times the sensitivity compared to a differential refractive index detector (RI) and is a versatile detector capable of accurately detecting semi-volatile and non-volatile components. Its wide dynamic range and excellent stability make it ideal for analyzing molecular weight distributions. This document discusses the detection of calibration standard samples and calibration curves, comparisons of sensitivity, and changes in retention time due to sample concentration, using polystyrene samples to compare RI and explain the characteristics and advantages of CAD. 【Features】 ■ High sensitivity detection: CAD achieves approximately 100 times the sensitivity compared to RI ■ Wide dynamic range: Accurately measures samples of diverse molecular weights ■ Detection in the polymer range: Effectively detects polymers with molecular weights up to 400,000 ■ Low concentration measurement: Minimal concerns about carryover or column loading even at low concentrations ■ Stability: Provides rapid stabilization and consistent results

• Analytical Equipment and Devices

In the quality control of plating solutions, the quantification of additives is an important factor. In particular, the quantification of sulfur-containing compounds that contribute to film quality adjustment and prevention of liquid decomposition is essential. This document provides accurate and highly reproducible analytical results using a method that does not require complex pretreatment. For the HPLC measurement conditions, an ion-pair reagent was added to the mobile phase, and an injection method was adopted to reduce the influence of sample impurities. As a result, sharp peaks can be obtained without being affected by metals and inorganic ions. Additionally, by comparing the chromatograms of the standard solution and the plating solution sample, it can be confirmed that the concentration of additives is maintained consistently. Furthermore, as an evaluation of reproducibility, the same sample was measured five times, demonstrating high reproducibility. 【Features】 ■ High-sensitivity quantitative analysis without complex pretreatment ■ High reproducibility using ion-pair reagents ■ Injection method that reduces the influence of metals and inorganic ions ■ Accurate quantification through comparison of standard solutions and actual samples ■ Highly reproducible analytical results

• Analytical Equipment and Devices

The Thermo Scientific Vanquish Split Sampler significantly reduces the effort and time associated with traditional manual dilution by allowing users to set up an automated dilution program for samples. This technical note verifies the accuracy and reproducibility of automated dilution of standard solutions through the measurement of DNPH-derivatized formaldehyde. Custom injections using user-defined programs enable easy execution of multi-step dilutions and automation of calibration curve creation. Furthermore, by utilizing the e-workflow of Thermo Scientific Chromeleon CDS, the entire process from analysis to report generation can be greatly streamlined, enhancing the reliability of analyses and increasing laboratory productivity. **Features** - High reproducibility and accuracy through automated dilution - Flexible dilution settings with custom injection programs - Automation of analysis with Chromeleon CDS e-workflow, eliminating human error - Significant reduction in effort and time compared to manual dilution - High-precision preparation capable of up to 20-fold dilution

• Analytical Equipment and Devices

This document introduces a method for the high-precision separation and quantification of four types of tocopherols contained in vegetable oils using the single-loop heart-cut 2D-LC method. Under the separation conditions of a reverse-phase system using a general ODS column, the separation of β-tocopherol and γ-tocopherol is difficult; however, the 2D-LC method allows for easy separation. In the first dimension, tocopherols and interfering components in the sample are separated, and in the second dimension, the four types of tocopherols (α, β, γ, δ) are separated. The repeatability of the standard samples achieved a high reproducibility with RSD < 0.1%. Additionally, measurements conducted on multiple vegetable oils showed that quantification was possible without the influence of interfering peaks. The single-loop heart-cut 2D-LC method is the simplest technique among 2D-LC methods, making it applicable for routine analysis and a useful tool for food analysis involving samples with a high content of matrix components. 【Features】 ■ High-precision separation achieved with the single-loop heart-cut 2D-LC method ■ Separation of β-tocopherol and γ-tocopherol, which is difficult in reverse-phase systems ■ Effective separation of interfering substances in food ■ High reproducibility with repeatability of RSD < 0.1%

• Analytical Equipment and Devices

The Thermo Scientific Vanquish Duo UHPLC system is a dual LC system equipped with two independent flow paths, allowing for parallel condition testing of different separation chemistries, such as the combination of ion exchange chromatography (IEX) and ion-pair reverse phase chromatography (IP-RP), within the same system. This technical document utilizes a method scouting kit to examine various ion-pairing agents, gradient conditions, pH, and column temperatures, achieving good peak shapes for mRNA and high-sensitivity detection of impurities. By simultaneously investigating IEX and IP-RP, it is possible to understand the separation characteristics of the sample, enabling efficient determination of separation conditions. With high separation capability and sensitivity, impurities can be effectively detected during post-transcription purification, allowing for reliable mRNA purification. **Features** - Simultaneous examination of two different separation chemistries (IEX and IP-RP) using the same device. - High-sensitivity detection of impurities in post-transcription purification through mRNA profiling. - Efficient determination of suitable separation conditions using the method scouting kit. - Examination of up to 10 solvents per column type to determine appropriate mobile phase conditions.

• Analytical Equipment and Devices

Quantitative analysis of gloss agents (saccharin and 2-butin-1,4-diol) in electroplating nickel plating solution using LC-MS helps maintain a consistent composition of the plating solution and greatly aids in the quality control of gloss agents. This method analyzes the components contained in the gloss agents under two different conditions based on their chemical composition. Additionally, samples can be easily measured by simply diluting them with water, and good results ranging from 92% to 108% have been obtained in addition-recovery tests. Furthermore, analytical conditions have been devised to achieve stable measurements over a long period. By using MS, detection is possible even at low concentrations in samples containing high concentrations of impurities, such as plating solutions, and detection is possible with both UV and MS. Measurement of not only gloss agents but also decomposition and by-products is possible, leading to further evaluation of the plating solution. For more details, please download the materials. 【Features】 ■ Quality control of gloss agents achieved through quantitative analysis using LC-MS ■ Measurement of gloss agents and decomposition/by-products is possible ■ Analysis of gloss agent components under two different conditions ■ Samples can be easily measured by simply diluting with water ■ Analytical conditions enable stable measurements over a long period

• Analytical Equipment and Devices

This technical document presents a case study on the highly sensitive quantification of eight components, including monosaccharides, disaccharides, and sugar alcohols, in beverages using the Thermo Scientific ISQ EC single quadrupole mass spectrometer. There are various methods for sugar analysis using HPLC, but traditional differential refractive index detectors have challenges such as sensitivity issues and the inability to perform gradient analysis. Additionally, while fluorescence detectors can detect low concentrations, they require derivatization, making the sample preparation complicated. The ISQ EC single quadrupole mass spectrometer enables the quantification of sugars at low concentrations ranging from a few to several tens of ng/mL, thanks to its high sensitivity and selectivity. Furthermore, its user-friendly device and analysis software allow easy operation for both beginners and experts in mass spectrometry, streamlining routine analyses and enabling the rapid acquisition of reliable quantitative data. 【Features】 ■ High sensitivity: Detection limit of a few to several tens of ng/mL ■ High selectivity: Accurate quantification unaffected by interfering components ■ Improved operability: No complex sample preparation required

• Analytical Equipment and Devices

This technical document presents a case study of the simultaneous analysis of polyphenols contained in beverages and health foods with high sensitivity, unaffected by other components. A 1.5 µm solid-core particle column was used for the analysis, separating 36 types of polyphenols under gradient conditions within 10 minutes. By using standard samples of each polyphenol, calibration curves and detection limits were confirmed, achieving good linearity with a coefficient of determination of over 0.997 and detection limits in the low ng/mL range. Additionally, in the spiking recovery tests conducted on multiple health foods and beverages, approximately 100% recovery was obtained, confirming accurate quantification without interference from food components. This system reliably separates and detects components with similar structures, such as polyphenols, providing reduced analysis time and high reproducibility. Furthermore, its compact design and ease of operation streamline routine analyses. 【Features】 ■ Simultaneous analysis of 36 polyphenol components ■ High separation using a 1.5 µm solid-core particle column ■ Detection limits in the low ng/mL range and high sensitivity ■ Good calibration curves with a coefficient of determination over 0.997 ■ Accurate quantification with approximately 100% recovery, unaffected by food components

• Analytical Equipment and Devices

This technical document introduces a post-column analysis system for accurately quantifying organic acids in various beverages. The analysis column uses ion exclusion mode, and by adding BTB solution post-column, it separates and detects ten types of organic acids with good reproducibility. The e-workflow feature, which supports operations in routine analysis, is a significant advantage as it fully automates the process from device startup to measurement and report generation. The HPLC system features a compact design that incorporates a dual pump with two pumps in one module for analysis and post-column solution delivery. Additionally, even in the event of an error, the automatic switching of valves prevents the post-column reaction solution from backflowing into the analysis column, allowing for safe adoption in routine analysis. 【Features】 ■ Accurate quantification of ten types of organic acids with good reproducibility of less than 1% ■ Separation of organic acids using ion exclusion mode columns, allowing measurement without matrix effects ■ Detection limits for organic acids in this method range from a few to 7 μg/mL ■ Automation of the process from device startup to report generation with the e-workflow feature ■ Ensured safety with automatic valve switching in case of errors

• Analytical Equipment and Devices

Many amino acids do not absorb ultraviolet (UV) light, making it difficult to improve sensitivity and selectivity with conventional analytical methods, which are also complicated and lack stability. This technical document introduces a case where a custom injection program feature in the auto-sampler of the Thermo Scientific Vanquish Core HPLC system was utilized to derivatize 20 types of amino acids simultaneously using a pre-column derivatization method for simultaneous analysis. This system enables highly accurate quantitative analysis as it is not affected by the degradation after the derivatization reaction. Validation using commercially available beverages showed that selective quantification was possible even in complex sample matrices such as food. 【Features】 ■ Simultaneous derivatization and analysis of 20 types of amino acids ■ High-precision quantitative analysis achieved through pre-column derivatization ■ Provides good linearity and high reproducibility ■ Selective detection even in complex sample matrices ■ Automation by the auto-sampler avoids human error and improves work efficiency

• Analytical Equipment and Devices

This technical document introduces a rapid and quantitative analytical method for the simultaneous detection of seven types of vitamins (vitamin A, vitamin D2, vitamin D3, and four types of vitamin E isomers) in infant formula using a conventional HPLC system with a diode array detector and a fluorescence detector, following offline solid-phase extraction (SPE) and two-dimensional liquid chromatography (2D-LC) analysis. By changing the traditional liquid-liquid extraction method to solid-phase extraction, the time required for sample preparation was reduced from 3 hours to 1 hour. Additionally, by simplifying the sample preparation and optimizing the separation conditions, the influence of the matrix was reduced, allowing for the detection of target substances with higher sensitivity. ■ Simplified sample preparation through two-dimensional liquid chromatography (2D-LC) analysis ■ Simultaneous separation analysis of vitamins A, D, E, and their isomers ■ Developed a method with higher recovery rates and sensitivity than liquid-liquid extraction ■ Simplified the preprocessing process and reduced analysis time by 2.5 times ■ Reduced the influence of the matrix and provided reliable data

• Analytical Equipment and Devices

Foods containing sugar often have a high content of sucrose, making it difficult to accurately quantify sucrose and other disaccharides (such as lactose and maltose) in actual samples due to insufficient separation. This technical document adopts a single-loop heart-cut 2D-LC method, where lactose and maltose are fractionated in the sample loop after sucrose elutes in the first dimension, allowing for the separation and analysis of lactose and maltose in the second dimension, thereby avoiding the influence of sucrose. Additionally, the charged aerosol detector (CAD) used in the detection allows for gradient analysis, providing greater flexibility in separating contaminants in a variety of food samples, enabling efficient analysis. This achieves high-sensitivity analysis that was difficult with conventional refractive index detectors (RI). 【Features】 - Accurate analysis by separating lactose and maltose in foods containing sugar - Separation from contaminants possible with the single-loop heart-cut 2D-LC method - Charged aerosol detector (CAD) allows for gradient analysis and accommodates diverse samples - Achieves high-sensitivity analysis that is difficult with conventional refractive index detectors (RI)

• Analytical Equipment and Devices

A universal charged aerosol detector (CAD) that measures various analytical target substances with consistent responsiveness can provide consistent area response on chromatograms regardless of the chemical structure of non-volatile analytes, ranging from ions to proteins. Additionally, its wide dynamic range allows for high-sensitivity detection. HPLC-CAD is utilized for the detection and quantification of compounds that are difficult to measure with UV detectors in various fields such as food, pharmaceuticals, and materials science. Please refer to the PDF for practical examples.

• Analytical Equipment and Devices

Have you ever experienced issues such as liquid leakage when transporting liquids in bottles by air? One concern when using plastic bottles for air transport is that changes in air pressure during transportation can cause liquid leakage. The Thermo Scientific Nalgene IP2 bottle is a product that complies with the United Nations recommended standards for transport containers for the storage and transport of important samples. We conduct internal pressure tests that meet the standards of the International Air Transport Association (IATA) for each lot. To distinguish it from other Nalgene bottles, "IP2" is engraved on the bottom of the bottle. ▼ Certificates can be issued - Product certificates can be issued for each lot. - Internal pressure tests are conducted for each lot, and a quality assurance certificate is attached. ▼ Recommended for customers like these - Those who want to export samples in bottles by air to overseas. - Those who may use bottles at higher internal pressures than usual. - Those who have experienced liquid leakage during air transport. If you would like a sample, please indicate this in the inquiry section.

• Plastic utensils and containers

We are introducing a comprehensive range of lab pH meters/ion meters, electrodes, and consumables. We also provide information on a variety of electrodes and the principles of pH measurement and dissolved oxygen.

• Water quality testing

The Thermo Scientific Sorvall X Pro series universal centrifuge combines powerful basic performance (large capacity & high speed) required for advanced applications with "ease of use" and world-class "safety." You can choose from the tabletop type Sorvall X1 Pro with a capacity of 1.6 L and the Sorvall X4 Pro series with a capacity of 4.0 L. 【Features】 ■ Maximum capacity: 4,000 mL (X4 Pro/X4F Pro) ■ Maximum capacity: 1,600 mL (X1 Pro) ■ Maximum centrifugal force: 25,830 ×g ■ A rich set of rotors to support advanced applications ■ AutoLock system for one-touch rotor fixation (no tools required) ■ Bio-safety compliant rotors that contain aerosols ■ Easy operation via a large touchscreen ■ Advanced features compatible with GMP environments, such as user management and log data memory ■ Reliable safety (compliant with international safety standard IEC61010-2-020) *For more details, please refer to the PDF document or feel free to contact us.

• centrifuge

● Adoption of Peltier elements in the cooling system ● Forced circulation system using a fan ● Equipped with 10 temperature program functions, including 10 steps ● RS232 interface for data output ● Stainless steel interior for easy cleaning and maintenance ● Supports simple customization such as adding shelves and ports *For more details, please download the PDF. Feel free to contact us.*

• incubator

The comprehensive catalog of Immuno Plates, known for its achievements and trust, has been revised. It includes guides on the principles and basics of ELISA, as well as how to select various conditions according to your applications. - Surface treatments (hydrophobic, low hydrophilic, hydrophilic, high hydrophilic surfaces) - Plate shapes (96 well, 8, 12, 16 well modular types) - Well shapes (flat bottom (F), round bottom (U, C), star well bottom) - Plate colors (clear, white, black) Additionally, we introduce the Imobilizer series (Imobilizer Amino, Imobilizer Streptavidin) with surfaces that have covalent bonds through spacers, which offer less steric hindrance than standard surface treatments, a high S/N ratio, and can shorten assay time without the need for blocking. Please download it and check the contents!

• Other inspection equipment and devices
• Plastic utensils and containers
• Other consumables

The Thermo Scientific(TM) Pipette Service Center was accredited in 2009 as a "calibration organization" compliant with the international standard "ISO/IEC 17025" by the Japan Accreditation Board (JAB) for laboratories and calibration organizations. We also offer calibration for pipettes from other brands, not just our own, at the same rates (special models are excluded). ● Suitable for those who: - Need precision management of pipettes due to revisions in regulations or standards - Feel limited by in-house calibration - Are requesting calibration of pipettes from various brands from each manufacturer 【ISO/IEC 17025 Calibration Service Course Overview】 1. Regular Calibration Available for applications of 10 or more units. More cost-effective than spot calibration. Price example) Single-channel: 10,800 yen/unit Multi-channel: 21,600 yen/unit 2. Spot Calibration Available for applications starting from 1 unit. Price example) Single-channel: 14,100 yen/unit Multi-channel: 24,100 yen/unit *Standard delivery time is approximately 2-3 weeks for 20-30 pipettes.

• pipette
• Other physicochemical equipment

The meaning of the operation buttons on the safety cabinet is hard to understand! I don't know when to replace the HEPA filter! I don't know how to respond when the warning lamp is lit! Have you ever had such experiences? Based on over 150 years of clean air technology, we have prepared a model that fuses "comfortable operability" and "information management functions" without compromising on "safety." Herasafe 2030i 【Features】 ● Easy operation with a full-color touch panel interface ● Automatically adjusts air flow balance and displays air flow speed ● Fully open sash design allows for cleaning and installation of large equipment ● Log management and user passcode settings available ● NSF/ANSI 49 international standard certification ● Supports data collection via OPC-UA ● Custom modifications available Maxisafe 2030i 【Features】 ● Unique triple HEPA filter with dust collection efficiency 100,000 times better than standard safety cabinets ● For handling chemotherapy drugs and prions ● EN 12469 international standard certification (European standard) ● Supports data collection via OPC-UA ● Custom modifications available

• cabinet

We are pleased to announce the release of the slide materials from the seminar program "Basics of Ion Chromatography," which was popular at the Dionex IC Technology Seminar 2019 - Basic Course on Chromatography! This seminar focuses on understanding and acquiring essential foundational knowledge related to analysis, such as the principles and theories of ion exchange separation and the basic components of the equipment, making it suitable for beginners in ion chromatography.

• Analytical Equipment and Devices

Have you ever had trouble with liquid retention in pipette tips? Our Thermo Scientific(TM) ART(TM) Low Retention Tips have the following features: - High hydrophobicity of the inner wall effectively suppresses hydrophilic adsorption of samples. - No risk of leaching as it is not processed with coatings or additives. - Effective even with small volumes and highly viscous liquids. Additionally, we received a 90% satisfaction rate from customers who tried our samples (according to our research*). Here are some feedback highlights from customers who have actually used the product: - The residual beads during immunoprecipitation have been significantly reduced, leading to an expected increase in final sample yield. - Solutions containing surfactants were expelled completely without residue. There was no significant decrease in hydrophobicity even with frequent pipetting. - There are no complaints from those involved in cell culture or protein work. We encourage you to try this comfortable ART Low Retention Tip for yourself. *According to our research Results from 151 customers who used samples provided by us between July 2016 and December 2016.

• pipette

We have created a quick reference guide as a pH electrode selection guide that summarizes information to help you choose the Thermo Scientific(TM) Orion(TM) pH electrodes tailored to your needs! It includes various electrodes suitable for different samples, ranging from standard electrodes to those resistant to chemicals, physically durable ones, micro-sampling, food applications, and viscous samples. Choosing the right electrode for your application is crucial for obtaining accurate and stable measurement results. Please make use of this as a tool for electrode selection. [If you would like a demo of the pH meter, please use the inquiry form below.]

• Analytical Equipment and Devices
• Other physicochemical equipment
• Water quality testing

The Jupiter Solid Nebulizer is a solid direct analysis system that uses a galvanolaser optical system. When used in conjunction with the robust Thermo Scientific iCAP Qnova series ICP-MS, it enables analyses that were previously impossible. **Analyses Achieved by Jupiter Solid Nebulizer ICP-MS** - Direct ICP-MS analysis of solid samples - Unique high-speed multi-point ablation allows direct application of quantitative methods such as standard addition to solid samples - Eliminates weighing errors and contamination during traditional dissolution processes, as well as solvent-related interferences during measurement, resulting in higher precision - Capable of analyzing difficult-to-dissolve and insoluble materials - Eliminates the need for acids and organic solvents, improving operator safety and reducing environmental impact and costs - Quantitative imaging of trace elements - Enables 2D/3D imaging of trace elements that are difficult to detect with surface analysis devices, utilizing the high sensitivity and quantitative accuracy of ICP-MS - Unique software features allow imaging based on quantitative concentrations - No need for standard samples with the same composition as the sample - Rapid analysis of extensive areas up to several square centimeters and depths of several hundred micrometers *You can view analysis examples of this product by clicking the link below "Application for Analysis Data Collection."*

• Analytical Equipment and Devices

◆Measurement of Zinc Oxide in Sunscreen Using Ion Chromatography with Visible Absorbance Detection◆ Sunscreens are classified as over-the-counter (OTC) drugs in the United States, and zinc oxide is one of the active ingredients that has received approval from the U.S. Food and Drug Administration (FDA) for use in sunscreens (with a maximum concentration of 25%). Zinc oxide is a powdered mineral that adheres to the outermost layer of the skin, acting as a broad-spectrum blocking agent that scatters, reflects, and absorbs ultraviolet radiation, providing protection from both UVA and UVB radiation, making it unique among sunscreen ingredients. The United States Pharmacopeia (USP) has developed monographs for FDA-approved drugs, including OTC medications, and is working to obtain the necessary information to maintain high-quality pharmaceuticals. It has also initiated a global effort to update many existing monographs across all official methods. As part of this USP initiative, the addition of an ion chromatography (IC) method for zinc measurement in General Chapter <591> is proposed. This method will serve as an alternative to the existing titration-based analytical methods in the monographs for zinc-containing pharmaceuticals. *Please download from the catalog at the bottom of the page.*

• Analytical Equipment and Devices

At the Thermo Scientific(TM) Pipette Service Center, we calibrate pipettes from various brands under the same conditions and at the same rates as our own pipettes. We support customers who are struggling with pipette management, as requesting calibration from each company individually can incur costs and effort, and there can be variations in delivery times depending on the manufacturer. 【Course Overview】 1. ISO/IEC 17025 Calibration Service To comply with quality system requirements, we issue ISO calibration certificates. Price example) Single-channel 14,100 yen/piece Multi-channel 24,100 yen/piece 2. Inspection Service We conduct inspections under the same conditions as our factory and issue inspection result reports. Price example) Single-channel 4,800 yen/piece Multi-channel 11,800 yen/piece *Full channel inspection for multi-pipettes For the multi-channel pipettes in the above courses, we conduct full channel inspections, ensuring peace of mind.

• pipette
• Other physicochemical equipment

【Triple Quadrupole Mass Spectrometer Lineup】 ■Thermo Scientific TSQ Altis Plus LC-MS/MS for high-sensitivity pharmacokinetics testing and biopharmaceutical analysis ■Thermo Scientific TSQ Quantis Plus LC-MS/MS for pharmacokinetics testing and analysis of pesticides and toxic substances requiring high sensitivity ■Thermo Scientific TSQ Fortis Plus LC-MS/MS for analysis related to environmental and food safety, as well as toxic substance analysis *The liquid chromatographs that can be connected range from general-purpose UHPLC to nano-flow LC for high-sensitivity analysis, two-dimensional LC for automated sample preparation, multi-channel LC for throughput improvement, and ion chromatography suitable for the separation of ionic compounds, allowing you to choose according to your analytical needs. Of course, these systems can be operated seamlessly with a single software.

• Analytical Equipment and Devices

This document introduces the "Titration Method for Total Acid Value in Petroleum Products Using Automatic Titration Equipment." The total acid value (TAN) of petroleum products is measured using the pre-programmed "T3 TAN Method." The sample is dissolved in a specified solvent and directly titrated to a pre-set endpoint at pH 11 using an alkaline titrant prepared with isopropanol. A blank is analyzed and automatically subtracted. [Contents (excerpt)] ■ Keywords ■ Program ■ Introduction ■ Recommended Equipment ■ Required Reagents and Solutions, etc. *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices

This document introduces the "Titration Method for Total Acid Value in Petroleum Products Using Automatic Titration Equipment." The Total Base Number (TBN) in petroleum products is measured using the pre-programmed method "T4 TBN Back." After dissolving the sample in a specified solvent, a standard perchloric acid (PCA) reagent is added. The sample is then back-titrated to the equivalence point using an alkali titrant prepared in glacial acetic acid. The back-titration complies with ASTM D2896, providing a fast and reliable endpoint. [Contents (Excerpt)] ■ Keywords ■ Program ■ Introduction ■ Recommended Equipment ■ Required Reagents and Solutions, etc. *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices

By using the Click Container, easy sample collection is achieved! Safe sample transportation! A 95 kPa vacuum test is conducted as a leak prevention feature: compliant with UK standard BS EN 14401. Leak tests are conducted: compliant with UK standard BS EN 14254. ● Convenient cap and body packaging for small animal dissection and laboratory use. ● Separate packaging for cap/body that is useful for automatic dispensing of solutions such as formalin, boric acid, and sodium thiosulfate in histology, urinalysis, and water analysis applications. ● Sterilized individual packaging convenient for use in clean rooms and similar environments. ● Easy-to-remove dispenser box type.

• Resin container

We will introduce analytical instruments that play an important role in quality checks and food analysis in general, including food ingredients, containers and packaging, functional components, flavors, and tastes. ◆ Example Applications ◆ 01 Carbohydrates 02 Bitter components 03 Lipids 04 Polyphenols 05 Antioxidant capacity measurement (ORAC method) 06 Organic acids 07 Amino acids 08 Foreign substances 09 Food contact materials 10 Identification of origin and raw materials 11 Odor analysis 12 Natural toxins 13 Allergens 14 Trace element analysis

• Analytical Equipment and Devices

We will send you a free sample kit in a box containing various bottles. Please use it to check and evaluate the compatibility of vials and bottles. If you would like a sample kit, please select "Request Sample" from the "Contact Us" section at the bottom of the page. Thermo Scientific Nalgene bottles reduce the risk of liquid leakage without gaskets due to their unique structure of bottle neck sealing and cap threading. Additionally, pressure tests are conducted for each lot to ensure there are no leaks. The main plastic resins are registered with FDA DMF numbers. They can be used for storing pharmaceuticals and high-quality liquids, as well as for domestic and international transport. We offer a wide range of sizes tailored to various applications, including 0.5 mL micro vials, 2 L, and 20 L. Both non-sterile and sterile products are available. The sample kit box contains various small bottles ranging from 10 to 60 mL, vials from 0.5 to 2 mL, dropper bottles, immuno plates, and transfer pipettes. *Please select "Request Sample" from the "Contact Us" section to apply.

• Other consumables

The Thermo Scientific(TM) Orion(TM) Star T910 pH automatic titration device measures the titratable acidity (TA) of orange juice as citric acid equivalent using the pre-programmed "T1 TitraAcidity" method. This application note introduces the method for measuring titratable acidity in orange juice using the automatic titration device. It provides detailed information on recommended equipment, the setup of the titration device, method modifications, and maintenance of the equipment. [Contents] ● Recommended equipment ● Required reagents and solutions ● Setup of the titration device ● Preparation of electrodes ● Sample preparation ● Sample titration ● Results ● Titration range ● Method modifications ● Titrant ● Maintenance of equipment and electrodes *For more details, please download the PDF.

• Analytical Equipment and Devices
• Other physicochemical equipment

◆Analysis Applications for Food Contact Materials and Food Packaging◆ Food contact materials include plastics, paper, wood, composites, glass, and metals, and there is a risk of substances such as chemicals and metals migrating from these materials into food. Regulations regarding these materials are complex, so it is necessary to efficiently monitor and control them using appropriate analytical methods. The eBook introduces various analyses of food contact materials, and you can access detailed information through the links in the document. ◆Workflow for Identification and Quantification of Unknown Impurities in Medical Devices, Pharmaceutical Packaging, and Food Contact Materials◆ Components that can cause harm by contaminating products, not only in food contact materials but also in pharmaceutical packaging materials, need to be highly controlled. In addition to explanations of a wide variety of contaminants, from volatile substances to high molecular weight non-volatile molecules and even metals, we also introduce the products necessary for analysis. *Please download from the catalog at the bottom of the page.*

• Analytical Equipment and Devices

The Dionex ICS-6000 HPIC system is a high-performance modular ion chromatography system with high reliability. Its robust system design allows for operation at up to 5,000 psi, providing consistently reliable results. As a high-end model of ion chromatography systems, it is designed for users looking to expand the possibilities of ion analysis. 【Features】 ■ High-speed, high-resolution, high-sensitivity analysis ■ Modular design compatible with all applications ■ Capillary IC compatible ■ Can be combined with eluent generators ■ Settable for 2 channels ■ Remote operation via tablet *For more details, please refer to the PDF materials or feel free to contact us.

• Analytical Equipment and Devices

The Vanquish Duo HPLC system achieves increased productivity and uptime without compromising the high performance, robustness, and ease of use that the Vanquish platform offers. Furthermore, it enables a deeper understanding of samples and allows for a quicker return on investment. 【Features】 ■ Three configurations possible by combining the Vanquish platform: ・Tandem LC: A system for effective utilization of detectors ・Dual LC: Two completely independent LCs realized in a single device ・Reverse gradient system: A system for quantitative analysis using charged particle detectors ■ The dual autosampler's injection unit is completely independent to avoid cross-contamination ■ Regulatory-compliant operating environment with Chromeleon *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices

This is a triple quadrupole mass spectrometer designed for high robustness, operability, and accurate quantitative analysis of complex matrix components found in samples such as food. 【Features】 ■ Maintenance-friendly OptaMax NG ion source ■ Sweep cone that reduces contamination in the ion source ■ Matrix separator ion guide introduction system ■ Neutral blocker that enhances robustness ■ Active collision cell that avoids crosstalk effects in multi-component analysis and improves sensitivity ■ Segment quadrupole that enhances consistency in ion behavior ■ Compatible with a method library for 440 pesticide components *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices

The Q Exactive UHMR quadrupole mass spectrometer boasts significantly improved sensitivity and high m/z mass resolution, providing a unique high-performance analytical solution suitable for studying the structure and heterogeneity of protein complexes. The Q Exactive UHMR mass spectrometer can perform native intact mass analysis and top-down analysis, offering structural details that cannot be elucidated by other methods. This enables a deeper understanding of protein functions, disease mechanisms, potential therapeutic targets, and biotherapeutic compounds.

• Analytical Equipment and Devices

The tribrid structure optimizes data accuracy and high qualitative capabilities, including various MSn analyses, for low molecular identification and structural analysis. The newly implemented data acquisition algorithm, AcquireX, selectively and automatically acquires comprehensive and high-quality mass spectra for a wide range of low molecules. 【Features】 ■ Equipped with quadrupole, Orbitrap, and ion trap ■ Resolution of 500,000 (FWHM @ m/z 200) ■ Two dissociation methods: CID and HCD ■ High-speed switching measurement for positive and negative ions ■ Dynamic scan management function ■ Built-in internal standard substance introduction system (optional) ■ Calibration and analysis parameters optimized for low molecular analysis ■ Automated efficiency of MSn spectrum acquisition by AcquireX ■ Assisted CE for real-time optimization of collision energy during analysis *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices

The Thermo Scientific Orion Star T910 pH automatic titration system is designed to enhance laboratory productivity by automating titration. By combining our core electrochemical technology with an advanced reagent dispensing system, we have achieved automated titration that is easier, more reliable, and more reproducible than manual methods. Please use the Orion Star T910 pH automatic titration system for applications such as the following acid-base titrations: • Titration acidity of juices and wines • Acidity of food • Alkalinity of water • Acidity and alkalinity of consumables • Total Acid Number (TAN) • Total Base Number (TBN) *Free rental is available. (Please contact us for details.)

• Analytical Equipment and Devices
• Other physicochemical equipment

The "Thermo Scientific(TM) Orion(TM) 2111XP Online Sodium Meter" has a long track record of sales in the field of industrial water in power plants and various plants, demonstrating reliable measurement performance in various analyses. To meet the stringent needs for ultrapure water measurement and high-acid cation exchange applications with a single system, we offer measurement application packages including an ammonia package, a diisopropylamine (DIPA) package, and a cation/high-acid package. 【Features】 ■ Detection limit of 0.1 ppb ■ Prevention of corrosion-related impacts ■ Easy to use with simple operation ■ High visibility unaffected by lighting conditions thanks to a large display ■ Incorporates ROSS Ultra electrode technology for high measurement stability ■ Ability to add a pH or ORP measurement module as a second channel ■ Option for a grab sampler available *For more details, please refer to the PDF materials or feel free to contact us.

• Other measurement, recording and measuring instruments
• others

Thermo Scientific(TM) Nalgene(TM) lab supplies are an excellent alternative to glass in many life science research labs. As general-purpose plastic products, we offer a wide range of items, including: ● Flasks ● Beakers ● Funnels ● Graduated cylinders ● Burettes ● Others We also provide fluoropolymer products that are inert to almost all chemicals and have exceptional resistance to temperatures from low to high. Innovative features enhance safety in research environments, such as beakers with handles, chemical identification cleaning bottles that make contents easy to see, and graduated cylinders designed to minimize rolling when stored on their side, making them widely used as labware. You can choose from various plastic materials, sizes, and designs to suit your application. *For more details, please refer to the PDF document or feel free to contact us.

• Plastic utensils and containers

We have compiled a comprehensive guide on the analytical methods for chemical compounds found in food contact materials and food packaging. We introduce various analytical methods tailored to the measurement targets. You can directly access more detailed technical information through the links in the eBook. ■ FCM and food packaging material solutions ■ Fast solvent extraction ■ GC and GC-MS ■ GC-HRAM ■ HPLC and UHPLC ■ LC-MS ■ LC-HRAM ■ Elemental analysis ■ Peer-reviewed academic

• Analytical Equipment and Devices