信州ＴＬＯ List of Products and Services

We introduce a new positive electrode material that solves the issue of "capacity degradation" that has been a challenge for conventional nickel-zinc batteries. This positive electrode material is based on the intercalation reaction of layered double hydroxides (LDH), which consist of divalent metal hydroxide ions and trivalent metal ions. The layered structure of LDH also helps to avoid capacity degradation caused by the nickel-zinc reaction, making it suitable as a positive electrode material. It contributes to the development of secondary batteries that excel in performance and safety, serving as an alternative to non-aqueous, acid-based secondary batteries. *For more details, please download the PDF or feel free to contact us.*

• Fuel Cells

Introduction to the practical examination of "zinc fuel cells" with excellent safety and storage properties. The electrochemical reduction of zinc is easy, but there are practical challenges in uniformly controlling the shape of large quantities of zinc. A method is needed to reduce zinc into a shape that facilitates "extraction from the electrolytic cell" and "introduction into air batteries." Aiming for the practical application of fuel cells that store energy in zinc instead of hydrogen, we are advancing the development of a generation method for zinc fuel that excels in storage and handling properties. 【Features】 ■ Round-trip efficiency: More than twice that of hydrogen ■ Fuel safety: High safety due to being solid ■ Catalyst cost: Inexpensive (activated carbon) *For more details, please download the PDF or feel free to contact us.

• Fuel Cells

We would like to introduce the research and development of a cancer screening test kit. "Calmodulin-binding peptide (CBP)" can be applied as a peptide aptamer for detecting midkine (MK) in screening test kits. Since it does not bind to similar epitopes, which is a challenge with antibodies, it has high specificity. Additionally, it can be manufactured using chemical synthesis methods, allowing for a cost reduction to less than 1/10 of conventional methods. [Features] ■ Binding affinity of MK-CBP - Strong intermolecular interactions confirmed ■ Specificity of MK-CBP binding - mtCBP (mutant type) showed high specificity for MK *For more details, please download the PDF or feel free to contact us.

• Other research reagents
• Other cells
• Other Analysis

Introduction to the application of internal exposure prevention and reduction technology for the thyroid in food and beverages. Oral compositions containing cyclodextrin (CD) strongly encapsulate radioactive iodine in the gastrointestinal tract, inhibiting the absorption of radioactive iodine in the small intestine. As a result, internal exposure of the thyroid to radioactive iodine is reduced. Currently, we are working with international organizations related to radiation protection to include this technology in recommendations for nuclear disaster situations. 【Features】 - Usable for preventive purposes: Can be taken even when the risk of internal exposure to radioactive iodine is low. - Can be taken at individual discretion: Contains CD, which is also a food, and has almost no side effects. 【Intended Uses】 As food and pharmaceuticals containing cyclodextrin: - Use during nuclear disasters - Use for healthcare workers who have long-term contact with patients undergoing treatment with radioactive iodine *For more details, please download the PDF or feel free to contact us.

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We would like to introduce the effects of Jerusalem artichoke extract on the alleviation of allergy symptoms. Using a pollen allergy model mouse, we compared groups that consumed tuber extract with those that did not. The results of our examination of "scratching frequency" and "serum IgE concentration," which is a cause of pollen allergies, revealed that the tuber extract significantly alleviates allergy symptoms. Additionally, we confirmed similar effects on allergy symptoms with extracts from the leaves of the Jerusalem artichoke. We are also identifying the active components that suppress allergy symptoms. [Published Content] ■ Effects of methanol extract from Jerusalem artichoke (tuber) on alleviating allergy symptoms ■ Effects of hot water extract from Jerusalem artichoke (leaves) on alleviating allergy symptoms ■ Identification of active components and comparison of yields from tubers and leaves *For more details, please download the PDF or feel free to contact us.

• Other food and beverage ingredients

We would like to introduce the "Virus Inactivation Filter" that we handle. This filter is made by three-dimensionally integrating activated carbon and a heater using a discharge plasma sintering method. It can be applied to air purifiers, air conditioner filters, and air purification in closed spaces. 【Features】 ■ Can be heated efficiently to virus inactivation temperatures (above 80°C) ■ Proven inactivation of "99.9% or more" with activated carbon and heat ■ Sintered and formed in bulk with "various shapes" and "pore amounts and sizes" *For more details, please download the PDF or feel free to contact us.

• Filters

Shinshu TLO Co., Ltd. (Headquarters: Ueda City, Nagano Prefecture) has recently launched a new technology introduction page to further promote technological collaboration with companies. This page features technology seeds from universities and research institutions across various fields, supporting the creation of opportunities for technology exploration and collaboration in corporate research and development departments and new business development departments. It broadly introduces technologies applicable to various industries, including manufacturing, healthcare, energy, and information and communication, without being limited to specific fields. We have also established a rapid response system for technology consultations and matching from the industrial sector, promoting the creation of new value through industry-academia collaboration. *For more details on the press release, please refer to the related link. Feel free to contact us for more information.

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We would like to introduce a new method for generating ultra-fine bubbles. High-quality, high-density ultra-fine bubbles can be produced. They can be generated in large quantities in a short time, eliminating cost constraints. Additionally, long-term stable storage is possible. Applications in factory cleaning, treatment methods, pharmaceuticals, and medical devices are anticipated. 【Features of the Ultra-Fine Bubble (UFB) Generation Method】 ■ High quality, low running costs, and large-scale production in a short time ■ A greater number of ultra-fine bubbles compared to existing commercial products ■ Control of bubble size from micro to nano ■ Flow rate control is possible *For more details, please download the PDF or feel free to contact us.

• Technical and Reference Books

We will deliver noteworthy technology information from universities and other institutions via email. - Interested in the latest research trends - Looking to find seeds for new developments and new businesses - Seeking collaboration with research institutions such as universities This is recommended for you. Please register using the QR code in the image or the "Related Links" below.

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This technology is a radiation therapy support system for cervical cancer that uses radiation therapy planning DICOM data as a visual aid 3D model. It can be utilized not only for intraoperative support but also for educational guidance by senior physicians and information sharing with other staff, making it applicable for non-clinical purposes as well. 【Features】 ■ Uses radiation therapy planning DICOM data as a 3D model for intraoperative visual support ■ The only necessary equipment is a head-mounted display (HMD), allowing for low-cost development and implementation ■ Enables high-resolution intraoperative support compared to ultrasound images *For more details, please download the PDF or feel free to contact us.

• Other information systems

I would like to introduce the "Estimation of Shear Force Using Piezo Wire Sensors" conducted at the Department of Mechanical Engineering, Tokyo Denki University. Using a force gauge, vertical loads were applied to stacked materials, and tensile tests were conducted using a motor under a total of 55 conditions, including 11 vertical load conditions and 5 motor voltage conditions. The estimation accuracy of the shear force was 92.5% for sensors processed into a circular shape and 93.1% for sensors woven into fabric. 【Key Points】 - Estimation of shear force from vibration measurements using piezo wire sensors - Real-time three-dimensional visualization of shear force and vertical load inside shoes *For more details, please download the PDF or feel free to contact us.

• Other analysis and evaluation services

We would like to introduce Saitama University's development of a "hybrid urination flow measurement device." This hybrid method (image + sound) estimates flow rate using urine images (Axis Switching) and sound energy, allowing for non-contact and hygienic measurements. It can also handle low flow rates and subtle flow variations through missing data estimation using Gappy POD. High-precision flow estimation is possible across the entire flow range. 【Features】 ■ Flow estimation using urine images (Axis Switching) ■ Flow estimation using sound energy ■ Missing data estimation using Gappy POD ■ Capable of handling low flow rates and subtle flow variations *For more details, please download the PDF or feel free to contact us.

• Flow Meter

We will introduce a technology developed at Saitama University for accurately detecting spatiotemporal phenomena arising from local climate and environmental conditions. By acquiring multiple imaging data sets that include coordinate and timestamp data, we calculate the probability that specific features predetermined within the imaging data are present using a deep learning model. In the real world, we calculate the average probability computed daily within a set grid and detect or estimate changes in phenomena from the resulting time series data. 【Features】 - It is possible to understand landscapes from imaging data with location information, such as from onboard cameras. - This technology enables the understanding of regional environments and landscapes that cannot be captured by satellite observations or drones. - It is expected to be useful for detecting disaster damage, abandoned farmland, deforestation, land cover changes, landscape changes, and heat environment changes such as urban heat islands. *For more details, please download the PDF or feel free to contact us.

• Other measurement, recording and measuring instruments

"SST" is a new vibration control program capable of achieving vibration control that meets constraints on maximum speed and maximum acceleration. By enabling vibration control in near-minimum time, it reduces transport time. Optimizing acceleration trajectories alleviates the load on the equipment. Please feel free to contact us when you need assistance. 【Advantages】 ■ 122ms (SST) < 142ms (existing technology) *Example of verification results from a prototype ■ Reduction in the number of switching operations: 4 times (SST) < 9 times (existing technology) ■ Positive and negative switching of maximum acceleration: none (SST) < present (existing technology) *For more details, please download the PDF or feel free to contact us.

• Other process controls

I would like to introduce the "biomembrane potential imaging using zebrafish" research being conducted at Saitama University. At the individual level, reliable membrane potential measurements can be performed in real-time from specific cell types and tissues, and potential applications for understanding disease symptoms and treatments are anticipated. There is no need for prior procedures such as dye injection in the observed individuals, and it is almost non-invasive, relying solely on optical imaging. [Results] ■ Neural activity in the zebrafish brain was detected through ASAP1 membrane potential imaging. ■ Successful optical measurement of membrane potential at the individual level and at both single-cell and group levels while the organism is alive. *For more details, please download the PDF or feel free to contact us.

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We would like to introduce a "angiogenesis inhibitor" through the suppression of CD9 expression (siRNA). As a result of verification using a rat corneal model, it was found that the suppression of CD9 expression significantly inhibited both the motility and invasiveness of endothelial cells. Additionally, the angiogenesis inhibitory effect was confirmed in both systems with different angiogenic factors (HGF and VEGF). 【Key Points】 ■ Confirmed significant suppression of motility and invasiveness in vitro ■ Clear angiogenesis inhibitory effect confirmed in vivo ■ An angiogenesis inhibitory therapeutic agent with universal effects against different angiogenic factors *For more details, please download the PDF or feel free to contact us.

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We would like to introduce a new technology for improving the strength of non-woven fabrics using thermoplastic resins. This technology has shown the potential to address the issue of degradation of core PET fibers, which has been a problem in conventional technologies. With this technology, it has become possible to create fusion points at lower temperatures than the degradation of PET, suggesting further enhancement of the strength and dimensional stability of needle-punched non-woven fabrics. 【Contribution to Companies, PR Points】 ■ Can contribute more to companies through application development ■ Scientific backing can be provided by conducting necessary additional experiments for implementation ■ Technical guidance for full-scale implementation, etc. *For more details, please download the PDF or feel free to contact us.

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We would like to introduce the "Development of Technologies Related to Early Healing of Bone Fractures." Based on the discovery of the phenomenon where osteoblasts are induced to align in a nano-periodic structure, we verified the regeneration of fractured areas using metal fixtures (bolts/sheets) with a nano-periodic structure. In animal experiments using rats, while complete regeneration was not achieved by four weeks post-surgery, partial induction of bone formation in the superficial layer was confirmed, preceding deeper bone regeneration. 【Verification Contents】 ■ Verification of early healing due to reduced alignment induction of osteoblasts ■ Verification of early healing using nano-periodic structures combined with bone healing promoting substances ■ Verification of early healing through mechanical vibration application *For more details, please download the PDF or feel free to contact us.

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Capsaicin is said to have effects that enhance immunity and energy metabolism, but it is not easy to consume due to its "spiciness." Capsiate is a related compound to capsaicin, and similar functional properties have been reported. However, capsiate is present in small amounts in peppers, making it a difficult component to commercialize. This technology is a method for producing peppers that contain a high amount of capsiate. This enables a stable supply of capsiate. *For more details, please download the PDF or feel free to contact us.*

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This is a technology that realizes "soft robots" that combine dexterity and flexibility. Inspired by the peristaltic movement of caterpillars, it enables the rotation and movement of objects while grasping them within the robotic hand. *For more details, please download the PDF or feel free to contact us.

• Other industrial robots

The "Body Movement Detection Panel and Sleep State Monitoring System" is a technology that can determine the states of "lying down," "getting up," and "leaving the bed" of care recipients based on body movement data obtained from the body movement detection panel. By using deep learning to "predict the awake state," notifications are sent to caregivers just before the person gets up. Additionally, since it is a panel type that can be placed under the mattress, it can be installed on various types of beds. [Features] - Non-contact, non-restrictive, highly versatile body movement detection panel - Notification possible 1-2 minutes before getting up *For more details, please download the PDF or feel free to contact us.

• Other safety equipment

We will introduce the "Omnidirectional Movement Device and Its Posture Control Method." The "Ball-riding Omnidirectional Vehicle" is a vehicle that can maintain dynamic stability, while the "Joint-type Omnidirectional Vehicle" is a vehicle that can realize an omnidirectional movement device by arranging multiple omnidirectional wheels and connecting the body and chassis with a flexible joint. The ball-riding type is envisioned as a means of transportation in commercial facilities (level ground) such as large stores, while the joint type is anticipated for applications like electric wheelchairs (support for caregivers and labor-saving). [Overview] ■ Purpose of this technology (Technical Background) ■ Technology related to Ball-riding Omnidirectional Vehicles ■ Technology related to Joint-type Omnidirectional Vehicles *For more details, please download the PDF or feel free to contact us.

• Other conveying machines

I would like to introduce the "Chemical Titration Method using Microchannels." Due to its cross-shaped microchannel design, it allows for easy and inexpensive device manufacturing, and measurements can be taken in just a few seconds, making it suitable for field analysis. Additionally, it can continuously measure titration values, making it applicable for inline analysis as well. 【Features】 ■ Cross-shaped microchannel ■ Measurement in seconds + portable ■ Continuous titration value measurement *For more details, please download the PDF or feel free to contact us.

• Analytical Equipment and Devices

Introducing "high-efficiency vibrators." By utilizing high vibration frequencies from higher longitudinal waves and unique electrode patterning, we achieve improved driving efficiency. The "skin sensation display" that leverages this technology operates at a driving voltage of 909.8 kHz, 10Vp-p, with a modulation frequency of 300Hz to 400Hz, providing a skin sensation similar to a rough texture like "gritty." 【Features】 ■ Improved driving efficiency ■ Applicable to various voltage materials *For more details, please download the PDF or feel free to contact us.

• Other electronic parts

Introducing the "Microencapsulation Technology for Self-Healing Functions." By combining microcapsules (MC) containing repair agents with metal catalysts that are less prone to degradation from heat, we achieve "self-healing materials" with excellent long-term stability. Potential applications include fiber-reinforced plastics (FRP), construction materials such as roofing and exterior walls, and coating materials like paints and sealants. 【Self-Healing Mechanism】 1. Disperse MCs containing catalysts and repair agents within the material. 2. When cracks reach the MC, the repair agent is released. 3. The repair agent and catalyst initiate a curing reaction, repairing the material. *For more details, please download the PDF or feel free to contact us.

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• Composite Materials

<How to Apply and Attend> If you wish to attend, please apply through the link "Apply for the Information Session Here" below. Application deadline: Until July 31, 2024 Once you apply, you will be able to watch the recorded session for about two weeks after the event date! ◆List of Presentations 1. Presenter: Associate Professor Yasuhiro Takasaka, Advanced Materials Research Institute "Achieving Easy Molding and Rapid Stress Relaxation with Acrylic-Based Vitromers" 2. Associate Professor Tomohiko Okada, Faculty of Engineering "Recycling Silicon Cutting Chips: Resource Recovery through Surface Modification of Powdered Silicon" 3. Assistant Professor Ren Tomizawa, Faculty of Textiles "Improving the Strength of Non-Woven Fabrics with Fibers Containing Adhesives" 4. Associate Professor Masahiro Shimizu, Faculty of Engineering "Development of Proton Secondary Batteries Using Non-Aqueous Electrolytes" 5. Assistant Professor Noriyasu Iwamoto, Faculty of Textiles "A Robot that Constructs Curved Surfaces to Change Appearance and Design Space" For detailed information and applications, please check "Apply for the Information Session Here"!

• Technical Seminar

Introducing "Trajectory Control of Bearingless Motor Rotating Shaft." Within the range of air gap, complex trajectories can be set, and stable control is possible even during high-speed rotation and acceleration/deceleration. The settling time to the target trajectory is "0.4 seconds." Our unique control system enables sequential trajectory correction. Please feel free to contact us when you need assistance. 【Features】 ■ Capable of setting complex trajectories within the range of air gap ■ Stable control even during high-speed rotation and acceleration/deceleration ■ Settling time to target trajectory is "0.4 seconds" (when accelerating from 937.5 to 3750 r/min on a prototype) ■ Feedback + Feedforward control + SFT (Sequential Fourier Transform) correction *For more details, please refer to the PDF document or feel free to contact us.

• Other processing machines

Citrulline is a type of recovery amino acid. - It is a precursor to ornithine. - It is sold as a supplement or pharmaceutical aimed at improving blood flow, alleviating arteriosclerosis, enhancing muscle growth, and recovering from fatigue. For more details, please refer to the PDF document or feel free to contact us.

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We would like to introduce "New Applications of Cellulose Nanocrystals." When a suspension of carboxylated oxidized CNC is impregnated or sprayed onto fabric, it adheres to the surface of the fabric through hydrogen bonding, demonstrating deodorizing functionality without damaging the material. The oxidized CNC can be removed along with odor-causing substances during washing, allowing for repeated use of the CNC. In addition to deodorization, we are also considering applications such as coloring. Please feel free to contact us if you are interested. 【Advantages】 ■ Deodorizing ability can be imparted to the fabric in advance (before the occurrence of odors) ■ Maintains the original physical properties of the fabric (does not damage) ■ Deodorizing ability can be easily applied and removed *For more details, please refer to the PDF document or feel free to contact us.

• fiber

Introducing "Meltblown Composite of Polycarbonate/Polypropylene." We have successfully developed a composite meltblown nonwoven fabric incorporating ultra-thick polycarbonate (PC) fibers. The incorporation of PC fibers has particularly increased the maximum pore diameter. The difference in capacity retention rate becomes significant at 2C or 100 cycles. Please feel free to contact us when you need assistance. 【Overview】 Fiber blending ratio 0-17%: Increased pore diameter, decreased thermal shrinkage rate ⇒ Improved thermal stability and increased pore diameter due to PC fiber blending. *For more details, please refer to the PDF document or feel free to contact us.

• plastic

"World's fastest decomposition rate" - Decomposes formaldehyde (1g/L) in 3 hours "Easy management, transportation, and handling" - Dried microbial cells can be stored long-term while maintaining activity "Minimal capital investment" - Addition of small pre-treatment tanks or direct addition *For more details, please refer to the PDF document or feel free to contact us.

• Wastewater/wastewater treatment equipment

"Optimize the intracellular arrangement of chloroplasts" - Selectable optimal blue light intensity for each plant species "Optimal light environment for cultivation purposes" - Control leaf shape through light environment (blue light + red light) "Improving productivity in plant factories" - Increased productivity possible through optimization of the light environment *For more details, please refer to the PDF document or feel free to contact us.

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"High-Precision Deep Body Temperature Measurement Using Dual Heat Flow Method" - Air layer on the side of the temperature sensor, two independent heat flow paths - Achieves medical device level accuracy (average error: ±0.2 to 0.3℃) "Compact Module" Configurable with Implementation Technology Only - SMD temperature sensor IC, printed circuit board - Size suitable for integration into wearable devices *For more details, please refer to the PDF document or feel free to contact us.

• Thermometer

This technology allows for free design of metal surfaces using lasers. It can be applied to metals that form anodic oxide coatings, such as aluminum, titanium, magnesium, and their alloys. The laser can also be realized using commercially available lasers (such as carbon dioxide lasers). 【Features】 ■ By irradiating the metal surface with a laser and performing partial coloring, free painting is possible. ■ After coloring, applying a chemical reaction (sealing) treatment results in a highly durable coating. ■ Common paints can be used, and it is also possible to create images that stand out using fluorescent paints. *For more details, please refer to the PDF document or feel free to contact us.

• Surface treatment contract service

The technology involves the production of cellulose nanocrystals (CNC) using wheat bran (the outer layer of wheat). The amount of carboxyl groups present on the surface is significantly higher compared to those derived from wood pulp or cotton. The amount of sulfate ester groups introduced through sulfuric acid hydrolysis is also relatively high, making it effective for functional performance on the surface. 【Features】 ■ Nano composite film - Light transmittance - Reinforcement effect ■ Fiber (wet spinning) - Tensile strength *For more details, please refer to the PDF document or feel free to contact us.

• Organic Natural Materials

We would like to introduce the "Universal 3D Nutrition Labeling System." A program has been developed that visually represents nutritional characteristics using colors, shapes, and sizes. The color of the sphere represents nutritional balance, while the size of the sphere indicates the amount of energy. [Features] - Easily understand the amount and ratio of energy and nutrients at a glance - Applicable to both food and dishes *For more details, please refer to the PDF materials or feel free to contact us.

• Other information systems

The technology is a surface modification technique for powdered silicon that enables the recycling of silicon cutting waste generated during the semiconductor manufacturing process. By using a sacrificial mold method, the surface of silicon particles is coated with hectorite, providing silicon materials suitable for industrial use. Please feel free to consult us for technical guidance, evaluation analysis, joint research, sample provision, etc. 【Features】 ■ Recycling silicon cutting waste into black pigments ■ Higher thermal conductivity compared to carbon and ferric oxide ■ Hydrophobically treated, well-dispersed in a mixture of soybean oil and water ethanol *For more details, please refer to the PDF document or feel free to contact us.

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We will investigate your company's needs and introduce you to suitable experts or technologies if available. Additionally, even if there are no matching technologies immediately, we will inform you when inventions that address your challenges arise. For more details, please visit the linked page and input your company's needs.

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This is a technology that effectively utilizes food residues such as fruit peels and press cakes, which have been discarded in the processing stages as unused resources. To use the natural pigments contained in the peels of fruits like apples, grapes, and persimmons as food materials, it is important to obtain an extract of the pigments without using extraction solvents such as acids or methanol that would compromise the original flavor. This technology enables the simple and efficient production of a liquid that extracts the natural pigments and functional components contained in the fruit peels.

• Machinery and equipment installation/dismantling/relocation

"High-pressure processed rice" is a high-functional rice that has been treated with water and heat, subjected to a pressure equivalent to the water pressure at a depth of 10,000 meters (100 MPa). Compared to white rice, brown rice contains a higher amount of polyphenols, as well as B vitamins, minerals, and dietary fiber, making it beneficial for health. We can process and provide the rice of your choice up to a few kilograms (contract required), so please feel free to inquire. [Features] - Particularly high in polyphenols (about 70% of brown rice) - Less prone to breakage during milling (reducing loss) *For more details, please refer to the PDF materials or feel free to contact us.

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In functionalization through surface modification, there is a technology that forms fine patterns on the surface of the workpiece using high-energy lasers or machining. While these methods have the advantage of being able to produce highly precise patterns, they face challenges such as the high cost of equipment and the difficulty of processing three-dimensional objects. This technology enables the formation of fine patterns on three-dimensional objects in a simple and cost-effective manner by applying the optical property of speckle to lithography. Features of the new technology: - Fine processing technology utilizing speckle light - Formation of fine dot-like random resist patterns on the surface of parts (approximately a few to several hundred micrometers) - Ability to form patterns collectively on the circumferential surface of cylindrical parts - Ability to form patterns collectively on the surfaces of parts with steps (step surfaces of several tens of millimeters) The resist patterns formed by this technology are expected to provide functionality to the surface of the workpiece. (Improvements in water repellency, hydrophilicity, dirt resistance, lubricity, anti-reflection, antibacterial properties, and biocompatibility, etc.)

• Other surface treatment equipment

○Overview of the Technology We have developed a method to improve detection sensitivity using enzyme-linked immunosorbent assay (ELISA) with nanobodies. We prepared a nanobody-polysaccharide conjugate by chemically linking nanobodies to water-soluble polysaccharides, and it was confirmed that the sensitivity in the solid-phase ELISA using this conjugate was improved compared to using the nanobodies alone. ○Comparison with Conventional Technology In ELISA using nanobodies as a substitute for conventional antibodies, there was a challenge of inactivation due to solid-phase immobilization and detachment from the substrate. This technology allows for the improvement of ELISA detection sensitivity by using water-soluble polysaccharides as a scaffold for solid-phase immobilization of nanobodies. ○Features of the Technology - Application of nanobodies in sandwich ELISA - Water-soluble polysaccharides protect nanobodies - Improved binding affinity due to aggregation of nanobodies - Suppression of nonspecific adsorption

• Other inspection equipment and devices

○Overview of the Technology By incorporating aggregation-induced emission (AIE) fluorescent materials into resin beads, it is possible to manufacture highly bright fluorescent beads that were not achievable with conventional fluorescent materials. Using these fluorescent beads enables the development of immunochromatography kits with higher sensitivity than before. ○Comparison with Conventional Technology 【Influenza】 Achieved a sensitivity increase of 1000 times compared to test kits using gold colloids as labeling substances. 【Novel Coronavirus】 Achieved a sensitivity increase of approximately 20 to 40 times compared to currently available test kits on the market. ○Features of the Technology - Utilizes AIE compounds as fluorescent materials - Developed highly bright fluorescent beads without concentration quenching - Developed a background reduction sheet for fluorescent immunochromatography - Developed immunochromatography kits with higher sensitivity than conventional products - A handheld ultraviolet irradiator has been developed.

• Other inspection equipment and devices

This is a capacitive humidity sensor that combines polyimide, which has excellent heat resistance and chemical stability, with MWCNT (multi-walled carbon nanotubes) and SWCNT (single-walled carbon nanotubes), achieving a response time on the order of 10 ms, which is 100 times faster than conventional sensors. Carbon nanotubes (CNT) have a nanoscale mesh structure, making them gas-permeable electrodes. It is also important that the upper electrode does not hinder the movement of gas molecules; for example, in the case of a humidity sensor that permeates water vapor, high hydrophobicity can be expected to enable a fast response. This technology improves response speed, sensitivity, temperature change suppression, and durability compared to conventional humidity sensors by attaching CNT as the upper electrode to a thin film of polyimide, whose electrical properties change due to water vapor or gaseous chemicals.

• Thermo-hygrometer

This is a method to solve the issue of "incomplete infiltration" in tissue regeneration materials. Using vacuum-pressure infiltration, we were able to introduce cells deep into porous materials (e.g., collagen, PLA, etc.). Subsequent proliferation and differentiation have also been confirmed.

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