一般財団法人材料科学技術振興財団　MST List of Products and Services

- We accommodate tests not only in accordance with standards but also tests tailored to your requests, even if they fall outside the standards. - We have a variety of fixtures for gripping and securing. Additionally, we can also handle the creation of custom fixtures.

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It is also possible to apply voltage to the sample, measure the temperature profile in the chamber, and conduct sampling evaluations during the specified cycle.

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- Visualization of attraction and repulsion due to the electric dipole effect of piezoelectric samples is possible. - Quantitative evaluation of the sample's expansion and contraction due to piezoelectric response is a reference value. - AFM images can also be obtained simultaneously.

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It is also referred to as HX-PES or HXPES. Due to high-energy X-ray excitation, it allows for bulk state evaluation up to approximately 50 nm deep, which is several to about 10 times deeper than conventional XPS, as well as damage-free evaluation of bonding states at interfaces. This device is a laboratory instrument equipped with a GaKα source (9.25 keV), which enables a reduction in the time lag from sample preparation to measurement. - Bulk-sensitive state evaluation (approximately up to 50 nm) - Non-destructive evaluation of buried interface bonding states - Evaluation using deep inner shell orbitals (avoiding overlapping Auger peaks in XPS, analysis using the non-split 1s orbital) It also includes options for measurements combined with sputtering using GCIB (Gas Cluster Ion Beam), angle-resolved measurements, Al source (1.49 keV), neutralization guns, and measurements under non-exposure to the atmosphere. - Damage-free sputter cleaning using GCIB (depth profiling is generally not possible) - Depth-direction comparison of bonding states using Al source and angle-resolved measurements - Evaluation under non-exposure to the atmosphere

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It is possible to evaluate organic materials such as organic EL and proteins, as well as solutions, substrates, thin films, and powders of luminescent materials. It is possible to evaluate not only the fluorescence spectrum but also at which wavelength the most emission occurs (excitation spectrum). By using low-temperature measurements (77K) and the built-in shutter, it is possible to separately acquire fluorescence and phosphorescence.

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The characteristic of methods such as ESI and FD, which are other soft ionization techniques, is that they can ionize polymers with molecular weights of tens of thousands, which are difficult to ionize using other methods. In MALDI-MS analysis, which combines MALDI with time-of-flight (TOF) mass spectrometry, mass spectra of polymer materials can be measured, allowing for qualitative analysis. By utilizing a mass spectrometer that switches between the high mass resolution spiral mode and the wide mass range linear mode, a broad range of materials can be evaluated. Furthermore, it is also possible to perform MS/MS analysis by colliding the sample molecular ions separated and detected in spiral mode with inert gas to induce fragmentation, allowing for the mass spectrum of the generated fragment ions to be measured. This enables the molecular structure analysis of polymer materials.

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NMR is a technique used to estimate the structure of compounds by observing the phenomenon (resonance phenomenon) in which atomic nuclei absorb specific electromagnetic waves corresponding to their respective chemical environments when exposed to electromagnetic waves in a magnetic field. The main constituent elements of organic compounds, such as hydrogen and carbon, allow for structural analysis and quantitative analysis of organic compounds through the measurement of 1H and 13C NMR spectra, based on their chemical shifts and integral intensities. Additionally, by analyzing the splitting patterns of the spectra, it is also possible to estimate the spatial relationships between the atomic nuclei. In inorganic compounds, insights regarding their structures can be obtained by measuring nuclei other than 1H and 13C, known as multinuclear nuclei (for example, 19F, 29Si, 31P, etc.). NMR includes solution NMR, used for samples soluble in solvents, and solid-state NMR, used for samples that are insoluble or poorly soluble in solvents.

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By analyzing characteristic X-rays using a wavelength dispersive X-ray spectrometer (WDX), measurements with higher sensitivity than those obtained with an energy dispersive X-ray spectrometer (EDX) can be achieved. Additionally, using soft X-ray emission spectroscopy (SXES) allows for the acquisition of information regarding local chemical bonding states.

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By changing the conditions of ultraviolet irradiation from carbon arc discharge, as well as the temperature, humidity, and water spray inside the chamber, it is possible to conduct accelerated testing of degradation that occurs due to outdoor use of products, parts, and materials, which takes a long time in nature.

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? Surface analysis of solid materials is possible ? Light elements such as Li, which are difficult to evaluate with EDX, can be assessed ? By using Ga ions as primary ions, evaluation can be performed with high surface resolution (on the order of tens of nm) ? The detection limit is as low as a few ppm (depending on the element), making it suitable for trace impurity element analysis compared to EDX ? Measurements can be conducted without atmospheric exposure by using a dedicated holder ? Since it is mounted on a SEM device, morphological observation and elemental analysis can be performed within the same chamber

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- It is possible to evaluate the durability against thermal and electrical stress by periodically applying a large current to the power device (On/Off state). - Equipped with a transient thermal resistance measurement mechanism (T3Ster), it measures the thermal resistance values of the entire power device and each component, allowing for quantitative assessment of degradation over cycles. - We also support the prototyping of test devices, so evaluation is possible even with the provision of individual components.

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- The transient thermal resistance value (Rthjc) of power devices, heat dissipation substrates, etc., will be measured based on JESD51-14. - If it is a power device, testing can be conducted with the actual device as is. When testing heat dissipation substrates, it is necessary to mount various semiconductor chips as heat sources. - We also support the prototyping of test devices, and evaluation can be conducted even with individual components provided.

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- This is a durability test in which a bias is applied in a direction that makes it difficult for current to flow between the collector-emitter and drain-source of power devices under high temperature or high temperature and humidity conditions. - During the test, the leakage current is monitored over time, allowing observation of behavior until insulation breakdown occurs. - It is compatible with various standards such as AQG324 and JEITA ED-4701.

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- The dielectric strength of the test sample is evaluated by applying high voltage to the test sample and measuring the voltage at which insulation breakdown occurs. - Testing in various temperature and humidity environments (such as 85°C/85%RH, 150°C, 175°C, etc.) is also possible. - It is also possible to measure the time until insulation breakdown occurs. By measuring the time to insulation breakdown at multiple voltages, a lifespan (V-t) curve can be drawn. - Testing in oil is also supported.

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Perovskite solar cells are composed of various types of organic materials depending on their purpose and role. This document presents an example of qualitative analysis of organic materials using LC/MS. By utilizing high-resolution MS spectra and MS/MS spectra, we were able to identify hole transport materials and additives in the hole transport layer. It is also possible to quantify the identified materials by comparing between samples or using standard samples. Measurement method: LC/MS Product field: Solar cells Analysis purpose: Composition evaluation and identification For more details, please download the document or contact us.

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Perovskite solar cells have excellent conversion efficiency in a film form and can be manufactured at low cost, leading to active research and development towards practical application. TOF-SIMS (Time-of-Flight Secondary Ion Mass Spectrometry) is effective for component analysis of the HTM layer (hole transport layer), evaluation of main components, dopants, and the depth distribution of impurities. This document presents a case study of depth analysis from the HTM layer to the perovskite layer. Measurement method: TOF-SIMS Product field: Solar cells Analysis purpose: Identification, distribution evaluation For more details, please download the document or contact us.

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Non-contact three-dimensional measurement device

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It is known that dipole interactions occur between spatially close atomic nuclei in molecules and crystals. The strength of this interaction is inversely proportional to the sixth power of the interatomic distance, allowing the measurement of interatomic distances using the SEDOR method (Spin Echo Double Resonance) with solid-state NMR.

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5-ALA (5-Aminolevulinic Acid) is a type of natural amino acid found in the bodies of plants and animals. It is known for activating mitochondria and is said to have effects such as fatigue recovery and mood enhancement when taken orally. This document presents a case study where the content of 5-ALA in black vinegar, amazake, sake, and wine, which are generally considered to have high levels, was quantified using LC-MS/MS. For black vinegar and amazake, analyses were conducted on two different products, and the quantification results were compared. Measurement method: LC/MS Product field: Food Analysis purpose: Composition evaluation and identification For more details, please download the document or contact us.

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FeFETs (ferroelectric transistors) using HfxZr1-xO2 (HZO) are expected to be candidates for next-generation transistors due to their high-speed operation and low power consumption, but they have the drawback of low polarization. To improve the characteristics of FeFETs, enhancing the ferroelectricity of HZO is effective, and methods have been proposed to apply stress to the HZO layer to increase the crystalline phases that exhibit ferroelectricity. This case evaluated the stress generated in each layer during cooling in a laminated structure composed of materials with different coefficients of linear expansion, such as TiN, W, Pt, and HZO, using the finite element method. Measurement Method: Computational Science, AI, Data Analysis Product Fields: LSI, Memory, Electronic Components, Manufacturing Equipment, Parts Analysis Objectives: Shape Evaluation, Structural Evaluation, Stress, Strain Evaluation For more details, please download the materials or contact us.

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There are individual differences in drug metabolism activity, and these differences are believed to be due to genetic polymorphisms. In the field of pharmacogenomics (PGx), there is an expectation for the application of personalized medicine that takes into account the effects of drugs, side effects, and drug interactions by investigating genetic polymorphisms. This document introduces the analysis of genetic polymorphisms related to drug metabolism using a designed analysis tool based on mass array methods. Genetic polymorphisms will be determined from the analysis results of SNPs (Single Nucleotide Polymorphisms) and CNVs (Copy Number Variations) for 20 drug metabolism-related genes.

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In the structural analysis of organic compounds using NMR, two-dimensional NMR is generally used in addition to one-dimensional NMR (1H-NMR and 13C-NMR) to confirm the correlations between peaks in one-dimensional NMR, allowing for the assignment of peaks and determination of the compound's structure. However, in compounds such as sugars that contain many similar structures, peaks can overlap even in two-dimensional NMR, making analysis difficult. In such cases, three-dimensional NMR is effective. This document presents examples of applying three-dimensional NMR using oligosaccharides as model compounds.

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X-ray CT allows for non-destructive observation of internal structures and dimensional measurements of products. This document presents a case study of a cylindrical lithium-ion battery (φ14mm×H50mm). X-rays were sufficiently transmitted from the outer casing to the interior electrodes, and initially, a wide-area observation was conducted to confirm the three-dimensional structure of the entire battery. Subsequently, by performing magnified observations on specific areas, we identified voids within the positive electrode, foreign substances between the positive and negative electrodes, and disturbances in the electrode layers. Additionally, measurements of the inter-electrode distance were conducted from the obtained cross-sectional images. Measurement method: X-ray CT Product field: Secondary batteries Analysis purpose: Shape evaluation, failure analysis, defect analysis, product investigation For more details, please download the document or contact us.

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Polyamines are a general term for aliphatic hydrocarbons that contain two or more amino groups. They are important components that exist within biological cells and are essential for normal metabolism, but it is known that their levels decrease with aging. On the other hand, by consuming polyamines, it is possible to replenish the reduced levels, which is why foods rich in polyamines are expected to have anti-aging effects. This document presents a case study of the quantification of three representative polyamines (putrescine, spermidine, and spermine) contained in soybean products using HPLC. Measurement method: HPLC Product field: Food Analysis purpose: Composition evaluation and identification For more details, please download the document or contact us.

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Lignin is an aromatic polymer component that accounts for about 30% of wood biomass, and attention is being drawn to its potential as an alternative to petrochemical raw materials and its use in engineering plastics. This document presents a comprehensive evaluation of lignin, starting from extraction from wood to chemical structure analysis. Measurement methods: NMR, LC/MS, GC/MS Product fields: Environment, Biotechnology, Polymer Materials Analysis purposes: Composition evaluation, identification, chemical bonding state evaluation, structural evaluation For more details, please download the document or contact us.

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Gallium oxide (Ga2O3) has a wider bandgap than SiC and GaN, and possesses excellent physical properties, making it a focus of attention as a material for power devices that can be expected to be high-efficiency and low-cost. Controlling impurity concentration and crystallinity, which influence the characteristics of the devices, is crucial for their development. This document presents the results of observations of the damage layer and changes in surface roughness caused by disturbances in the crystal structure due to ion implantation, under various annealing conditions. Measurement methods: TEM, AFM Product fields: Oxide semiconductors, power devices Analysis objectives: Shape evaluation, structural evaluation For more details, please download the document or contact us.

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In high-power lithium-ion batteries (LIBs), it is important to design the system to suppress the decomposition of the electrolyte during the charge and discharge processes. By adding components with low redox stability, it is possible to inhibit the decomposition of the main solvent during these processes and to form a high-quality SEI (Solid Electrolyte Interphase). By evaluating the redox stability of the electrolyte components through simulations, we can obtain indicators of the susceptibility of each component to decomposition during charge and discharge cycles, which can lead to the design of SEI components and characteristics. Measurement methods: Computational science, AI, data analysis Product field: Secondary batteries Analysis purpose: Evaluation of chemical bonding states and others For more details, please download the materials or contact us.

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A film (SEI) is formed at the interface between the anode of lithium-ion batteries (LIB) and the electrolyte, and its characteristics significantly affect battery performance. Research and development of functional electrolytes aimed at generating films with excellent ionic conductivity that contribute to the stability of batteries is underway. Quantum chemical calculations can be utilized in the design of such electrolytes and films. This document evaluates the electron affinity of solvents and additives in LIB electrolytes through quantum chemical calculations and assesses their reduction resistance. Additionally, the structure of reduction products can be estimated from bond dissociation energy. Measurement methods: Computational science, AI, data analysis Product field: Secondary batteries Analysis purpose: Composition evaluation, chemical bonding state evaluation For more details, please download the document or contact us.

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In semiconductor manufacturing processes, the contamination of impurities can lead to a decrease in characteristics and manufacturing yield, making the prompt identification and quantification of impurity elements crucial. At MST, we qualitatively analyze impurity elements using TOF-SIMS (Static-SIMS) and quantitatively measure the detected elements in the depth direction using D-SIMS (Dynamic-SIMS), enabling the evaluation of impurities within devices. This document presents a case study of measuring metal impurities in alkali-free glass.

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In recent years, environmental pollution and human exposure caused by per- and polyfluoroalkyl substances (PFAS) have garnered attention. Conducting blood tests is important to understand the exposure situation of PFAS. 【Test Items】 1. Simple quantitative test for PFOS and PFOA 2. Precise quantitative test for specific PFAS (PFOS, PFOA, PFHxS) and PFNA 3. Customized testing (testing for PFAS other than PFOS and PFOA) *Consultation required ◇Test Specifications Sample: Blood (whole blood, serum, plasma) can be tested even if hemolyzed. Required sample volume: 1 mL Quantification limit: 0.5 ng/mL *Upon request, analysis of PFAS other than PFOS and PFOA, testing with small sample volumes, and testing of samples other than blood are also possible. Please contact us for details. <Notes> - This testing service is intended for research purposes. Please be careful not to use it for clinical diagnosis or treatment of humans or animals. - Inquiries from individuals are not accepted, so please understand in advance.

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In precision machinery, vacuum devices, and semiconductor manufacturing equipment, contamination of the materials used can adversely affect product quality and the stable operation of the equipment. In this case, we handled glass components with disposable gloves of different types and analyzed the organic contamination adhered to the glass components using GC/MS analysis with a gas concentration device. By evaluating the contamination of the materials, it is possible to identify the components causing defects, eliminate the sources of material contamination, and consider changes to the materials.

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Rosmarinic acid, carnosol, and carnosic acid, which are abundant in plants of the Lamiaceae family represented by rosemary, are said to have antioxidant and anti-aging effects. In particular, rosmarinic acid is known as a functional ingredient included in some functional foods because of its effectiveness in reducing temporary irritability and daytime drowsiness. This document presents a case of quantifying rosmarinic acid, carnosol, and carnosic acid in cosmetics containing rosemary leaves and rosemary extract using HPLC. Measurement method: HPLC Product field: Food and cosmetics Analysis purpose: Product investigation, composition evaluation, identification, quantification For more details, please download the document or contact us.

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When impurities are mixed into metallic materials, depending on the combination of elements, it can affect the reduction of toughness and corrosion resistance. Therefore, it is important to understand the amount of impurities in metallic materials for quality control. GDMS can simultaneously analyze 77 elements without standard samples, making it effective for impurity analysis of samples with unknown contained elements, regardless of the matrix. This document presents a case study of impurity analysis of FeCoNi alloys using GDMS. Measurement method: GDMS Product field: Manufacturing equipment and parts Analysis purpose: Trace concentration evaluation For more details, please download the document or contact us.

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The analysis of odor components is effective for evaluating the scent that characterizes a product and for identifying the causes of unpleasant odors. Many odor components exist as stereoisomers, and isomers can have completely different scents from each other. When distinguishing and analyzing stereoisomers, methods such as NMR may be used; however, this case will introduce an example using GC/MS. Chromatography allows for the clear separation and evaluation of target components from other components. Additionally, by using columns designed for isomer separation, it is possible to evaluate various stereoisomers that cannot be separated using general-purpose columns. Measurement method: GC/MS Product fields: Cosmetics, daily necessities, food, environment Analysis objectives: Composition evaluation, identification, product investigation For more details, please download the materials or contact us.

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Fluoropolymer materials are chemically stable and possess various properties, making them widely used in industrial machinery, semiconductors, and electronics. LDI-MS (Laser Desorption Ionization Mass Spectrometry) is an analytical method that can ionize fluoropolymers with molecular weights of around several thousand while maintaining their molecular structure, allowing for the determination of the repeating units and molecular weights of fluoropolymers, as well as the estimation of end group compositions and structures. This document presents a case study on the structural analysis of perfluoropolyether (PFPE), which is used as a base oil in lubricants and heat transfer fluids. Measurement method: MALDI-MS Product field: Polymer materials Analysis purpose: Composition evaluation and identification, chemical bonding state evaluation For more details, please download the document or contact us.

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We conducted Slice & View on a SiC transistor where the leak location was identified using a backside emission microscope, and performed magnified observation and SEM-EDX analysis at the confirmed destruction site. Bright contrast was observed in the reflected electron images, indicating the segregation of Si and Ni. It is believed that some segregation of elements such as Si and Ni occurred due to the destruction caused by the leak. Measurement methods: Slice & View, SEM-EDX, EMS Product field: Power devices Analysis purpose: Failure analysis, defect analysis, product investigation For more details, please download the materials or contact us.

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For the SiC transistor, where the leak location was identified using a backside emission microscope, cross-sectional SEM observation was conducted using Slice & View. With Slice & View, it is possible to capture images of the leak location without missing it by performing cross-sectional observations at a pitch of several tens of nanometers around the leak area. By converting the SEM images into 3D, the leak path can be confirmed. Measurement method: Slice & View, EMS Product area: Power devices Analysis purpose: Failure analysis, defect analysis, product investigation For more details, please download the materials or contact us.

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The tape stripping method is a technique for removing the stratum corneum from the skin surface using adhesive tape, and it is an effective method for evaluating the permeability of active ingredients in cosmetics and beauty devices to the skin. Products containing tranexamic acid, known for its whitening properties (such as lotions and emulsions), were applied to a person's arm, and the process of stripping the stratum corneum with adhesive tape was repeated 30 times after a certain period. By extracting multiple pieces of adhesive tape with a solvent and analyzing the extract using LC-MS/MS, the content of tranexamic acid in the stratum corneum was quantified to evaluate its permeability to the skin. Measurement method: LC/MS Product field: Cosmetics Analysis purpose: Composition evaluation and identification For more details, please download the materials or contact us.

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Gallium nitride (GaN), a wide bandgap semiconductor, is used in a wide range of fields such as power devices and communication/optical devices. When fabricating devices, the shape and roughness of the wafer surface significantly impact device performance. During the growth of GaN wafers, a step-terrace structure is formed on the surface due to stress effects from lattice mismatch with the supporting substrate. This document introduces a case where the step-terrace structure of the GaN substrate surface was visualized using AFM, and the terrace width, step height, surface roughness, and off-angle were evaluated. Measurement method: AFM Product fields: Power devices, electronic components, lighting Analysis purpose: Shape evaluation, structural evaluation For more details, please download the document or contact us.

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In the manufacturing of semiconductor devices, the control of impurities such as dopants is a crucial process. When focusing on ion implantation, even slight differences can affect quality and performance, making precise control necessary. The high reproducibility of SIMS analysis is ideal for the development and maintenance of these processes.

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We rapidly and accurately measure proteins and hormones present in human blood and urine with high sensitivity and precision. The ECLIA method (Electrochemiluminescence Immunoassay) involves reacting antibodies (antigens) labeled with chemiluminescent substances with magnetic particle-bound antibodies (antigens), and measuring the amount of light emitted from this immunocomplex through a redox reaction on an electrode in the presence of TPA (Tripropylamine). In addition to over 60 test items corresponding to specialized fields such as thyroid, cardiology, and gynecology, we can also perform quantitative tests for antigens and antibodies related to infectious diseases, including the novel coronavirus.

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Power devices are attracting attention from the perspective of power and energy conservation as switches for high voltage and large current. In power devices, wiring defects and electrical failures occur due to the application of high voltage. Additionally, identifying and analyzing the causes of defects is essential for improving product reliability. This document presents a case study where the identification of defective areas was conducted using EMS (Emission Microscopy Method), and the analysis of defect causes was evaluated using SCM (Scanning Capacitance Microscopy) and SEM (Scanning Electron Microscopy). Measurement methods: EMS, SCM, SEM Product field: Power devices Analysis purpose: Failure analysis and defect analysis For more details, please download the document or contact us.

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SNP (Single Nucleotide Polymorphism) refers to the parts of the DNA sequence that differ by a single nucleotide among individuals. It is believed that SNPs can lead to different characteristics such as physical traits and are also related to drug response. Therefore, SNP analysis is expected to be applied in personalized medicine. This document introduces the characteristics of real-time PCR and mass array methods among SNP analysis techniques. It is effective to choose the method according to the specific SNP locations, number of SNPs, and their frequencies that need to be investigated.

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Real-time PCR is a method that detects the amplification of DNA fragments from PCR reactions as a fluorescent signal for each cycle. This introduces SNP (Single Nucleotide Polymorphism) analysis using the probe method of real-time PCR. Specific base sequences (probes) labeled with a reporter (fluorescent dye) and a quencher (quenching substance) are used to repeat the three steps shown below: 1) to 3). By using different reporters for each base, the SNP base is identified from the fluorescence intensity. Reactions at each step: 1) Thermal denaturation DNA is converted from double-stranded to single-stranded. 2) Annealing and hybridization Primers and probes specifically bind to single-stranded DNA. 3) Extension reaction The probe is degraded by the extension reaction of the primer, releasing the reporter from the quencher, resulting in fluorescence.

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Acetate cellulose, obtained through the acetylation of cellulose known as a wood component, has high biodegradability and is widely used as synthetic resin, fiber, and film. It is known that the physical properties, such as solubility, change significantly depending on the degree of acetylation (degree of substitution of acetyl groups), making the evaluation of the degree of acetylation very important for industrial applications. This document presents a case study evaluating the degree of acetylation of commercially available acetate cellulose using 13C-NMR analysis. Measurement method: NMR Product fields: Biomass, polymer materials, cosmetics, daily necessities Analysis purpose: Structural evaluation, product investigation For more details, please download the document or contact us.

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